Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics by ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong

“…The results indicated that HDPs significantly reduced the levels of pro-inflammatory factors such as interleukin-4 (IL-4), interferon-gamma (IFN-γ), and tumor necrosis factor-α (TNF-α) in mice with intestinal injury induced by alcohol, decreased the levels of lipopolysaccharide (LPS) and lipopolysaccharide binding protein (LBP), increased the level of α-amylase (AMS), and upregulated the tight junction protein Claudin 1, thereby improving intestinal barrier function. 16S rRNA sequencing revealed that compared to mice gavaged with alcohol at 114 µL/20 g mb, HDPs increased the abundance of the Lactobacillus genus and reduced alcohol exposure-induced disorders in gut microbiota diversity and structure. Metabolomics analysis found that HDPs could regulate bile acid metabolism and reduce the levels of bile acids (especially taurocholic acid and chenodeoxycholic acid) in the intestine of alcohol-exposed mice. …”
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人胚胎干细胞神经分化的方法探讨

“…【目的】 利用新建系的人胚胎干细胞株SYSU-7,运用胚体形成的方法,探讨不同的分化条件对胚胎干细胞神经分化的影响【方法】 首先检测人胚胎干细胞株SYSU-7的Oct4SSEA4(stage-specific embryonic antigen-4)TRA-1-60和AKP(Alkaline phosphatase)等胚胎干细胞特异性标志物的表达及体内外三胚层分化的能力;之后,应用含20% Knockout Serum Replacement (KSR)的培养液和神经干细胞培养液(neural progenitor medium, NPM)分别诱导细胞形成悬浮的拟胚体(悬浮时间为4 d或7 d),然后将拟胚体贴壁于多聚鸟氨酸(Polyornithine, PO)和纤维粘连蛋白(Fibronectin, FN)包被的培养皿中继续培养4 ~ 10 d在分化的不同时间点利用免疫荧光染色的方法检测胚胎干细胞和神经细胞相关的标志性抗原【结果】 SYSU-7胚胎干细胞表达未分化细胞特异性标志Oct4SSEA4,TRA-1-60,AKP染色呈强阳性,在体内外具有向三胚层分化的潜能;在体外诱导其向神经分化,结果发现KSR培养液比神经干细胞培养液更有利于胚胎干细胞的神经分化,悬浮生长7 d的拟胚体贴壁后出现特征性的玫瑰花环样结构(rosette structure)的时间更早数量更多【结论】 SYSU-7细胞系具有自我更新及多向分化潜能等胚胎干细胞特性本实验为研究人胚胎干细胞的神经分化提供了新的细胞模型和研究思路…”
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A proposal to measure the resilience of the Andalusian Commnunity Social Services by Elena Ferri-Fuentevilla, Ana Vallejo-Andrada, Aleix Morilla-Luchena, Rocío Muñoz Moreno

“…Critical indicators to assess social service resilience were put forward, in line with the research conducted by Kruk et al. who propose a resilience index for healthcare. Structural indicators, such as budget allocation and personnel, play pivotal roles, though data availability challenges persist, particularly in municipalities with over 20,000 inhabitants. …”
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Prevalence, Infectivity, and Associated Risk Factors of Hepatitis B Virus among Pregnant Women in Yirgalem Hospital, Ethiopia: Implication of Screening to Control Mother-to-Child T... by Anteneh Amsalu, Getachew Ferede, Setegn Eshetie, Agete Tadewos, Demissie Assegu

“…A total of 475 pregnant women were recruited, and data on sociodemography and potential risk factors were collected using a structured questionnaire. In addition, blood samples were tested for HBsAg, and HBsAg positive samples were retested for HBeAg using commercially available strip test. …”
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Analysis of the Multilevel Impact of Social Network Quality on Personality Dimensions in Purchasing by Maryam Akhavan Kharazian, Sona Shafieirad

“…Data analysis was performed using partial least squares structural equation modeling (PLS-SEM) with SmartPLS software.   …”
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Boards' strategic involvement models: Past, present, and future by Bozhinovska Tihona, Eftimov Ljupcho

“…Study design/methodology/approach: Having in mind that boards' strategic involvement is a multi-disciplinary area, we first conducted an integrative literature review, to detect the competing groups of models, and afterwards we conducted a semi-structured literature review in order to identify the most important topics in this area and to draft the future research agenda. …”
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Marker-assisted breeding of hybrid lines of <i>Triticum dicoccon</i> (Schrank) Schuebl. × <i>Triticum aethiopicum</i> Jakubz. with purple grain by P. I. Stepochkin, E. I. Gordeeva, Е. K. Khlestkina

“…The content of anthocyanins in whole-grain flour was measured in 12 lines, a structural analysis of plants was carried out, and their quantitative characteristics were assessed.   …”
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Effect of Mining Thickness on Overburden Movement and Underground Pressure Characteristics for Extrathick Coal Seam by Sublevel Caving with High Bottom Cutting Height by Yongkang Yang, Yanrong Ma, Chunxu Ji, Tianhe Kang, Xingyun Guo

“…Some conclusions can be drawn as follows: (i) under the “beam-hinged cantilever beam rocks” structure theory, the rock pillar thickness which needs to be controlled increases linearly as a function of mining thickness is achieved, and the reason of increased of support resistance in full-mechanized caving mining in extremely thick seams is explained in the theory; (ii) based on the results of the theoretical analysis and the lab simulation tests, the law of the abutment pressure peak is inverse to the full-seam mining thickness, and the distance between abutment peak and working face is proportional to the full-seam mining thickness, that is to say that the damage range of overlying strata increased; (iii) there are three working states of loading support in extrathick coal seams, such as normal circumstance, lower main roof pressure, and higher main roof pressure, meanwhile these states keep changing; (iv) under the guarantee of stope safety conditions, due to lower support strength, it will benefit the special thick seam top-coal caving under normal circumstance; (v) increasing the supporting strength can balance the impact loading under the lower main roof pressure, guaranteeing valid support for roof strata; (vi) by releasing high pressure, due to lower production, lower recovery rate of coal and other measures guarantee the stability of the stope support in the case of the higher main roof pressure.…”
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Magnitude and Associated Factors of Unintended Pregnancy among Pregnant Women at Saesie Tsaeda Emba Woreda Eastern Zone of Tigray, North Ethiopia, 2018 by Gebrehiwot Gebremariam Weldearegawi, Kidanemaryam Berhe Tekola, Berhane Fseha Teklehaymanot

“…Data was collected though face to face interview by structured questioner. It was entered, clean and analyzed using SPSS version 20. …”
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Numerical Weather Data-Driven Sensor Data Generation for PV Digital Twins: A Hybrid Model Approach by Jooseung Lee, Jimyung Kang, Sangwoo Son, Hui-Myoung Oh

“…The proposed model utilizes a hybrid data-driven model structure combining supervised learning-based long short-term memory (LSTM) and unsupervised learning-based generative adversarial network (GAN) to enhance both average and variance accuracy. …”
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Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment by Ma G, Li B, Diao J, Zhang Y, Zhang B, Wu D, Gui H, Zhong J, Zhu H, Zhang D

“…Meanwhile, the antibacterial effects showed 99% of bacteria died after 10 min under the action of a 2 W/cm2 laser and the structure of bacteria was destroyed. Finally, the transcriptomic results suggest that bacteria death may be related to membrane destruction, metabolic disorders, and transport damage. …”
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Malapposed Struts with Cre8, Biomatrix, and Xience Stents Assessed with OCT Immediately after Implantation and at 6-Month Follow-Up: Can the Different Biomechanical Characteristics... by Cristina Giglioli, Emanuele Cecchi, Chiara Formentini, Marco Chiostri, Niccolò Marchionni, Salvatore Mario Romano

“…Therefore, the malapposition observed at six-month follow-up in our study population could be mainly considered as acquired and attributable to biomechanical reasons due to the structural differences among the three stents. This trial is registered with Clinical Trials.gov Identifier: NCT02850497.…”
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APPLICATION OF OPTICAL CHARACTER RECOGNITION AND MACHINE LEARNING TECHNOLOGIES TO CREATE AN INFORMATION SYSTEM FOR AUTOMATIC VERIFICATION OF OFFLINE TESTING by Vadym Ziuziun, Nikita Petrenko

“…To save time, some educators use test sheets to structure responses, simplifying grading tasks. Consequently, developing a system that automates the grading of offline tests has become increasingly relevant. …”
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Ecological typology of woody vegetation of the Starohut forest massif as a component of the restoration of disturbed ecotopes by Olena Tykhonova, Tatiana Marukha, Petro Rybalko, Serhii Butenko, Serhii Horbas

“…The study aimed to determine the typological structure of the Starohut forest massif within the Desniansko-Starohutskyi National Nature Park based on the Ukrainian school of forest typology by Alekseev-Pogrebnyak. …”
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Multilevel relationships and loyalty in the microfinance industry: evidence from Tanzania by Amani Gration Tegambwage

“…Regression techniques and structural equation modeling were utilized to analyze the data. …”
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Geology, Fluid Inclusion, and H–O–S–Pb Isotope Constraints on the Mineralization of the Xiejiagou Gold Deposit in the Jiaodong Peninsula by Peng Chai, Zeng-qian Hou, Hong-rui Zhang, Lei-lei Dong

“…Mineralization and alteration are structurally controlled by the NE-striking fault. Three stages of mineralization were identified with the early stage being represented by (K-feldspar) sericite quartz pyrite, the middle stage by quartz gold polymetallic sulfide, and the late stage by quartz carbonate. …”
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Prevalence, Antimicrobial Susceptibility Pattern, and Associated Factors of Urinary Tract Infections among Pregnant and Nonpregnant Women at Public Health Facilities, Harar, Easter... by Degu Abate, Dadi Marami, Shiferaw Letta

“…Pertinent data were collected through a face-to-face interview using a structured questionnaire. The midstream urine specimen was collected and cultured on cysteine-lactose-electrolyte-deficient agar and blood agar. …”
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FEATURES OF THE MODEL OF A SPECIALIZED GEOSPATIAL DATABASE FOR VISUALIZING INDICATORS OF HUMAN SOCIO-ECONOMIC SECURITY IN WARTIME CONDITIONS by Zakharii S. Varnalii, Oleksii P. Fedchenko, Ihor V. Pampukha, Ihor V. Tolok

“…It examines the role of GIS in studying the impact of war on individual socio-economic security and proposes a model structure for a specialized geospatial database to visualize socio-economic indicators of occupied regions using the ArcGIS system as an effective decision-making support tool in management. …”
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Improving general practitioners’ approaches to functional somatic syndromes: a pilot training program with a focus on compassion and communication by Gonthier Ariane, Linder Audrey, Sommer Johanna, Despland Jean-Nicolas, Ambresin Gilles

“…The qualitative study consisted of five individual semi-structured interviews and one focus group of five persons, investigating the impact of the training session on the clinical practices, as perceived by the participants. …”
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Biofilm as a supracellular organization of pathogenic bacteria by B.P. Kuzminov, K.D. Mazhak

“…The search for new active substances with anti-biofilm activity based on the analysis of literature data on the structure of bacterial biofilms, mechanisms of their resistance to antimicrobial agents was the purpose of this work. …”
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