Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study by Manel Mateu‐Salat, Nicole Stanton‐Yonge, Frederic Sampedro Santaló, José Ignacio Vela, Jesús Díaz Cascajosa, Eva Safont Pérez, Daniela Rego‐Lorca, Ana Chico

“…Our group described subclinical cognitive alterations, structural brain differences, and increased levels of light chain neurofilament (NfL) in people with T1D and impaired awareness of hypoglycaemia. …”
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Women and birth partners’ experiences of cervical ripening at home and in hospital by Cassandra Yuill, Mairi Harkness, Helen Cheyne, Boo Charkin, Monica Ferreira, Eloise Price, Amarnath Bhide, Mairead Black, Kathleen Boyd, Neelam Heera-Shergill, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Sarah J. Stock, Rosemary Townsend, Linda J. Williams, Christine McCourt

“…Methods We undertook a qualitative study of women and their birth partners’ experiences of cervical ripening at home and in hospital. Semi-structured interviews explored experiences, acceptability and consequences of cervical ripening. …”
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“It doesn’t make any sense to even try”: the disruptive impact of COVID-19’s first wave on people with chronic pain using medical cannabis in New York by Yuval Zolotov, Jacinta Lomba, Megan Ghiroli, Mariya Masyukova, Julia H. Arnsten, Joanna L. Starrels, Jonathan Ross, Chinazo O. Cunningham, Deepika E. Slawek

“…Methods We conducted 1:1 semi-structured qualitative telephone interviews from March through May 2020 with a convenience sample of 14 individuals enrolled in a longitudinal cohort study. …”
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Green synthesis and characterization of NiO/Hydroxyapatite nanocomposites in the presence of peppermint extract and investigation of their antibacterial activities against Pseudomo... by Ali Shakerimoghaddam, Hayder Jihad Majeed, Ali Jawad Hashim, May Jaleel Abed, Layth S. Jasim, Masoud Salavati-Niasari

“…As a result of the interesting structural properties of nanomaterials, nanoscience-based methods have emerged as promising ways to increase the movement of existing antimicrobials. …”
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A new species of Astragalus (Fabaceae) from the Irano-Turanian biodiversity hotspot: an integrative approach by Zahra Karbalaei, Ali Bagheri, Ali Asghar Maassoumi, Twan Rutten, Frank R. Blattner

“…The new species is distinguished by unique stipule characteristics, leaflet shape, inflorescence structure, and seed micromorphology. Molecular phylogenetic analysis using ITS and ycf1 sequences reveals that A. kuzehrashensis forms a clade with A. chehreganii and A. hakkianus, although it exhibits genetic differences. …”
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circICMT upregulates and suppresses the malignant behavior of bladder cancer by Xin Luo, FangMei Xie, Guoqiang Qin, Ge Zou, Xu Lu, Chaofeng Zhang, Zeping Han, Ying Zhao, Xiaoyu Song, WenFeng Luo, Yongsheng Li, JinHua He, Jian Shen

“…Background: Circular RNA (circRNA) is a new type of endogenous single-stranded RNA with a covalently closed circular structure. Increasing evidence shows that circRNA plays an important role in regulating gene expression in tumors. circICMT is a circular RNA produced by the ICMT gene. …”
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Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations by Andrea C. Thoonsen, Anika Gans, Toby T. Broeders, Ilse van Beusekom, Diana M. J. Delnoij, Martine C. de Bruijne, Hanneke Merten

“…Methods In this qualitative study, we conducted semi-structured interviews with 35 representatives of 24 different guideline organizations. …”
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Cognitive Deficit-Related Interhemispheric Asynchrony within the Medial Hub of the Default Mode Network Aids in Classifying the Hyperthyroid Patients by Mengmeng Zhi, Zhenghua Hou, Yuqun Zhang, Yingying Yue, Ling Li, Yonggui Yuan

“…Recent studies suggest that abnormal structure and function in the brain network were related to cognitive and emotional impairment in hyperthyroid patients (HPs). …”
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Patient experience with eosinophilic esophagitis symptoms and impacts on daily life based on in-trial qualitative interviews by Calvin N. Ho, Harald Fjällbrant, Evan S. Dellon, Cecilio Santander, Marc E. Rothenberg, Julie Bailey, Shehan McFadden, Jason Ritchie

“…This study aimed to understand patients’ experiences with EoE. Methods Semi-structured longitudinal interviews were conducted with patients from MESSINA, a phase 3 placebo-controlled trial evaluating benralizumab for EoE. …”
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Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review by Amanda Cristina Dias de Oliveira, Sher Ali, Carlos Humberto Corassin, Sana Ullah, Karina Nascimento Pereira, James Leon Walsh, Nataša Hojnik, Carlos Augusto Fernandes de Oliveira

“…Additionally, cold atmospheric plasma-driven degradation of mycotoxins involves structural modifications, breaking key molecular bonds that reduce toxicity. …”
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Subgroups of cognitive impairments in schizophrenia characterized by executive function and their morphological features: a latent profile analysis study by Yuyan Huang, Weiyan Wang, Gangrui Hei, Tiannan Shao, Li Li, Ye Yang, Xiaoyi Wang, Yujun Long, Jingmei Xiao, Xingjie Peng, Chuhan Song, Jingda Cai, Xueqin Song, Xijia Xu, Shuzhan Gao, Jing Huang, Dongyu Kang, Ying Wang, Jingping Zhao, Yunzhi Pan, Renrong Wu

“…Across subgroups, significant gradient features of brain structure were exhibited in fronto-temporal regions, hippocampus, and insula. …”
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Disruption of seasonal influenza circulation and evolution during the 2009 H1N1 and COVID-19 pandemics in Southeastern Asia by Zhiyuan Chen, Joseph L.-H. Tsui, Jun Cai, Shuo Su, Cécile Viboud, Louis du Plessis, Philippe Lemey, Moritz U. G. Kraemer, Hongjie Yu

“…The internal movement structure within Southeastern Asia markedly diverged during the COVID-19 pandemic season, and to a lesser extent, during the 2009 A/H1N1 pandemic season. …”
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Ruxolitinib and oHSV combination therapy increases CD4 T cell activity and germinal center B cell populations in murine sarcoma by Ravi Dhital, Yeaseul Kim, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Alexia Martin, Kevin A. Cassady

“…RUX+oHSV therapy also increased cytokine-expressing CD4(+) populations, predominantly granzyme B(+) cytotoxic-like, interferon (IFN)-γ(+) T helper type 1 (Th1)-like, and interleukin (IL)-21(+) T follicular helper (Tfh)-like phenotypes, within the tumor infiltrates, suggestive of potential tertiary lymphoid structure development in the treated tumors. Here, we illustrate the utility of a high-dimensional spectral flow cytometry panel that permits simultaneous evaluation of intratumoral CD4/CD8 T cell, Treg, γδ-T cell, natural killer T (NKT) cell, B cell, NK cell, monocyte, macrophage, granulocyte, myeloid-derived suppressor cell (MDSC), and dendritic cell functional changes from RUX+oHSV-treated MPNSTs.…”
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PHAST. The Panchromatic Hubble Andromeda Southern Treasury. I. Ultraviolet and Optical Photometry of over 90 Million Stars in M31 by Zhuo Chen, Benjamin Williams, Dustin Lang, Andrew Dolphin, Meredith Durbin, Julianne J. Dalcanton, Adam Smercina, Léo Girardi, Claire E. Murray, Eric F. Bell, Martha L. Boyer, Richard D’Souza, Karoline Gilbert, Karl Gordon, Puragra Guhathakurta, Francois Hammer, L. Clifton Johnson, Tod R. Lauer, Margaret Lazzarini, Jeremiah W. Murphy, Ekta Patel, Amanda Quirk, Mariangelly Díaz Rodríguez, Julia Christine Roman-Duval, Robyn E. Sanderson, Anil Seth, Tobin M. Wainer, Daniel R. Weisz

“…We also present seamless population maps of the entire M31 disk, which show relatively well-mixed distributions for stellar populations older than 1–2 Gyr, and highly structured distributions for younger populations. The combined PHAST + PHAT photometry catalog of ∼0.2 billion stars is the largest ever produced for equidistant sources and is available for public download by the community.…”
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Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids by Su-Jin Lee, Eunji Kim, Yeeun Jeong, Jae Boum Youm, Hyoung Kyu Kim, Jin Han, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Sung Joon Kim, Hyang-Ae Lee

“…The hCOs, characterized by expression of key cardiac markers (cTnT) and functional ion channels (Cav1.2, Nav1.5, hERG), exhibited structural and electrophysiological properties reflective of human cardiac physiology. …”
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Practice patterns among early-career primary care (ECPC) physicians and workforce planning implications: protocol for a mixed methods study by Richard J Gibson, Tara Sampalli, Tara Kiran, Richard H Glazier, Agnes Grudniewicz, Kimberlyn McGrail, David Snadden, Ian Scott, M Ruth Lavergne, Laurie J Goldsmith, David Rudoler, Emily Gard Marshall, Megan Ahuja, Doug Blackie, Fred Burge, Steve Hawrylyshyn, Lindsay Hedden, Jacalynne Hernandez-Lee, Kathleen Horrey, Mike Joyce, Adrian MacKenzie, Maria Mathews, Rita McCracken, Madeleine McKay, Charmaine McPherson, Goldis Mitra, Gail Tomblin Murphy, Sabrina T Wong

“…We will conduct semi-structured in-depth interviews with family medicine residents and early-career PCPs and analyse survey data collected by the College of Family Physicians of Canada. …”
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A qualitative study on the impact and participation in the AGELESS multidomain intervention: Insights from older adults with cognitive frailty and their caregivers by Ying Qian Ong, Suzana Shahar, A’isyah Mohd Safien, Norhayati Ibrahim, Ai-Vyrn Chin, Francesca Mangialasche, Miia Kivipelto, Devinder Kaur Ajit Singh

“…Methods This qualitative study was conducted following the completion of AGELESS multidomain intervention. Semi-structured interviews covering domains such as perceptions, benefits, barriers, facilitators, and program preferences were conducted among 17 older adults with CF and 10 caregivers following the completion of the intervention. …”
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Time to act: Institutional mental health support for Ukrainian academic staff during wartime by Natalia Tsybuliak, Volodymyr Vakhitov, Hanna Mytsyk, Hanna Lopatina, Maryna Nesterenko, Artem Polulyakhov, Yuriy Petrushenko

“…The study underscores the importance of structured mental health support in fostering resilience within the academic community, with implications for policy and practice in war-affected educational environments. …”
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Cancer-associated fibroblasts and their role in tumor progression by M. S. Ermakov, A. A. Nushtaeva, V. A. Richter, O. A. Koval

“…The stromal elements of a malignant tumor can promote cancer progression and metastasis. The structure of the tumor stroma includes connective tissue elements, blood vessels, nerves, and extracellular matrix (ECM). …”
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Stability of a Roadway below a Coal Seam under Dynamic Pressure: A Case Study of the 11123 Floor Gas Drainage Roadway of a Mine in Huainan, China by Pingsong Zhang, Yuanchao Ou, Chang Liu, Binyang Sun, Chong Xu

“…The field data obtained showed that, when stabilized by rock bolts and other fixed components in the surrounding rock mass of the floor gas drainage roadway, under the influence of mining, the area of concentrated stress appeared at a depth of 20.7 m, when cracks eventually formed, but the overall structural stability of the surrounding rock mass remained good. …”
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