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35521
A Review: CRISPR Cas System and the Mechanism With an Inhibition of Binding of CRISPR Cas‐9
Published 2025-01-01“…This review emphasizes the effect of DNA structure and chromosomal protein on Cas 9 binding with a distinct classification of Cas types. …”
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35522
Exploring the interplay between social connectedness, job control, and organizational commitment: the mediating role of work engagement among Chinese teachers
Published 2025-01-01“…Social connectedness, job control, and work engagement were measured using self-reported scales. Structural equation modeling (SEM) was utilized to examine the hypothesized relationships. …”
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35523
The Strange Case: The Unsymmetric Cisplatin-Based Pt(IV) Prodrug [Pt(CH3COO)Cl2(NH3)2(OH)] Exhibits Higher Cytotoxic Activity with respect to Its Symmetric Congeners due to Carrier...
Published 2022-01-01“…The biological behavior of the axially unsymmetric antitumor prodrug (OC-6-44)-acetatodiamminedichloridohydroxidoplatinum(IV), 2, was deeply investigated and compared with that of analogous symmetric Pt(IV) complexes, namely, dihydroxido 1 and diacetato 3, which have a similar structure. The complexes were tested on a panel of human tumor cell lines. …”
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35524
Methods Research on Correction for Intracranial Metal Artifacts Based on Prior Image Utilization
Published 2025-01-01“…Results: Compared with linear interpolation and the ADN algorithms, this algorithm achieves the highest structure similarity and peak signal-to-noise ratio and lowest root mean square error in corrected images. …”
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35525
Insight into the Molecular Imaging of Alzheimer’s Disease
Published 2016-01-01“…Multimodal neuroimaging techniques have indicated changes in brain structure and metabolic activity, and an array of neurochemical variations that are associated with neurodegenerative diseases. …”
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35526
Effects of Anodization-Assisted Electrodeposition Conditions on the Fabrication of CuO-Cu2O Coatings on Nanoporous Stainless Steel
Published 2020-01-01“…The present study investigated influences of HClO4 concentration, reaction temperature, and load voltage on the morphology, structure, and composition of the coatings. SEM images showed that appropriate nanopores with an average size of about 93 nm were formed on the stainless steel surface and then were successfully filled with CuO-Cu2O. …”
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35527
Mesoscale heterogeneity is a critical determinant for spiral pattern formation in developing social amoeba
Published 2025-01-01“…Together with perturbation experiments, our detailed analysis of the structural change in mesoscale heterogeneity and associated wave dynamics demonstrated the functional importance of mesoscale heterogeneity in generating the spiral wave pattern, whose experimental observations were first realized. …”
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35528
An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders
Published 2019-01-01“…This modification leads to a charge shift, which affects the protein structure, protein-protein interactions, and hydrogen bond formation, and it may cause protein denaturation. …”
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35529
Identification of a simplified mathematical model of an unmanned aerial vehicle
Published 2020-08-01“…The results of computer modeling confirmed the validity of the synthesized mathematical model obtained on the basis of structural and parametric identification. This approach can be used to obtain simplified mathematical models that are used to solve problems of synthesis and optimization of control systems not only for UAVS, but also for other dynamic objects.…”
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35530
Perspectivas docentes sobre la implementación del enfoque orientado a la acción en entornos rurales: Estudio de caso único
Published 2025-01-01“…Using a qualitative case study design, semi-structured interviews were conducted with two English as a foreign language teachers and a rural primary school principal during June and July 2023. …”
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35531
Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
Published 2017-01-01“…In this paper, we will review some current scientific research on how our experiences are able to modulate the structural organization of the brain and how a healthy lifestyle (regular physical activity, correct sleep hygiene, and healthy diet) appears to positively affect cognitive reserve.…”
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35532
Boost Full Bridge Bidirectional DC/DC Converter for Supervised Aeronautical Applications
Published 2014-01-01“…First, a boost full bridge electrical structure is selected, adopting a Parallel Input Parallel Output (PIPO) interleaving technique and an optimal turns ratio selection for the transformers in order to reduce both weight and size of the equipment. …”
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35533
Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
Published 2025-01-01“…Herein, we demonstrate that human STELLA (hSTELLA) is inadequate, while mouse STELLA (mSTELLA) is fully proficient in inhibiting the abnormal DNA methylation and oncogenic functions of UHRF1 in human cancer cells. Structural studies reveal a region of low sequence homology between these STELLA orthologs that allows mSTELLA but not hSTELLA to bind tightly and cooperatively to the essential histone-binding, linked tandem Tudor domain and plant homeodomain (TTD-PHD) of UHRF1, thus mediating ortholog-specific UHRF1 inhibition. …”
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35534
Fracture characteristics of slag-based geopolymer mortars with recycled aggregates under mode I and mode II Loading
Published 2025-02-01“…This study concludes that while SGPM with RFA offers environmental benefits, careful consideration of RFA proportions and notch-to-depth ratios is crucial to maintain desired structural properties.…”
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35535
ENHANCING THE SMALL RUMINANT VALUE CHAIN USING SWOT ANALYSIS IN MAFRAQ GOVERNORATE, JORDAN
Published 2024-12-01“…Surveys were conducted with 156 out of 5824 farmers, and semi-structured interviews were carried out with other stakeholders in the value chain to gather qualitative data in 2021. …”
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35536
Beyond Cations: Expanding the Horizons of Ferrocene-Based Electrochemical Sensors for Neutral and Anionic Molecules
Published 2024-12-01“…Ferrocene (Fc) has long been celebrated for its remarkable redox properties and structural versatility, making it a cornerstone of electrochemical sensor development. …”
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35537
Temperature Field and Gradient Effect of a Steel-Concrete Composite Box Girder Bridge
Published 2021-01-01“…The temperature gradient heating and cooling model fitted by the measured temperature field can be used as a reference for the structural design of similar local bridges.…”
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35538
Multi-step multivariate forecasting of transmission power in NPPs using operational and meteorological data
Published 2025-02-01“…In this study, we explored how to effectively handle the long-term dependence problem and various data characteristics to increase the forecasting accuracy of transmission power in NPPs by introducing a Seq2Seq model with an encoder-decoder structure and an attention mechanism, beyond traditional time series deep learning models, especially LSTM. …”
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35539
Human Security in Asia: Interrogating State, Society, and Policy, edited by Debasish Nandy, and Debtanu Majee. Palgrave Macmillan, Singapore, 2024. XXI, 346 pp. https://doi.org/10....
Published 2024-12-01“…The different chapters of this book analyze the structured and organized dimensions of human security that shed light on the economic, food, health, community, environment and political security conditions in Asian countries. …”
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35540
Optimal Scheduling Strategy for Regional Microgrid considering Large-Scale Access of Electric Vehicles
Published 2022-01-01“…In recent years, renewable energy, especially photovoltaic (PV) generation, has been widely applied in commercial and residential areas, forming the structure of regional microgrids (MG). On the other hand, as large-scale electric vehicles (EVs) are connected to the regional MG, their disordered charging and discharging will enable extremely bad effects. …”
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