An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India... by Vaman Khadilkar, Tarun Reddy Katapally, Jasmin Bhawra, Neha Kajale, Rubina Mandlik, Vivek Patwardhan, Demi Miriam, Dipali Ladkat, Chidvilas More, Ketan Gondhalekar, Anuradha Vaman Khadilkar

“…The long-term data analysis plan includes longitudinal modelling, time-series analyses, structural equation modelling, multilevel modelling and sex-based analyses to investigate growth trajectories and intergenerational patterns of health risks. …”
Get full text

Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This would suggest that education and self-management skills should be seen as an integral component of asthma management and should be incorporated in structured patient care to achieve optimal asthma control.…”
Get full text

A bioinformatic search for correspondence between differentially expressed genes of domestic versus wild animals and orthologous human genes altering reproductive potential by M. P. Ponomarenko, I. V. Chadaeva, P. M. Ponomarenko, A. G. Bogomolov, D. Yu. Oshchepkov, E. B. Sharypova, V. V. Suslov, A. V. Osadchuk, L. V. Osadchuk, Yu. G. Matushkin

“…Belyaev’s discovery of destabilizing selection during the domestication of animals and that this selection affects only gene expression regulation (not gene structure) and influences systems of neuroendocrine control of ontogenesis in a stressful environment. …”
Get full text

Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

“…Furthermore, HG9-91-01 was found to protect the retinal structure and reduce the loss of retinal layers in an acute glaucoma model. …”
Get full text

Diagnosis of hepatocellular carcinoma using liquid biopsy-based biomarkers: a systematic review and network meta-analysis by Yutong Jiang, Yutong Jiang, Shangwen Qi, Shangwen Qi, Rongrong Zhang, Rongrong Zhang, Ruixia Zhao, Yu Fu, Yuxuan Fang, Yuxuan Fang, Mingyi Shao

“…Subsequent analysis of circRNA and mRNA highlighted hsa_circ_000224, hsa_circ_0003998, KIAA0101 mRNA and GPC-3mRNA as the optimal diagnostic biomarkers for distinguishing HCC from healthy populations and liver disease patients, respectively. Well-structured prospective studies are crucial to comprehensively validate these findings.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/,identifier CRD42024521299.…”
Get full text

Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies by Lindiwe Khumbuzile Zuma, Ofentse Jacob Pooe, Nonduduzo Hlengiwe Mabaso, John Alake, Vincent A. Obakachi, Sinethemba Yakobi, Nothando Gasa, Rajshekhar Karpoormath, Mthokozisi Simelane

“…FTIR experiments confirmed interactions between the compounds and the secondary structure of the proteins. Direct protein–ligand interaction studies analysis using microscale thermophoresis (MST) showed a KD value of 0.1036 ± 0.6001 µM for the PfLDH-BA complex and 0.7473 ± 0.3554 µM KD value for PfLDH-IMA. …”
Get full text

Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation by Yudi Li, Yudi Li, Alona Armstrong, Alona Armstrong, Christopher Simmons, Noah Z. Krasner, Noah Z. Krasner, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez

“…Marked differences in vegetation across micro-patches indicated that GPVs drive changes in plant community composition, structure, and productivity. Compared to open spaces, vegetation near and within the PV array footprint displayed greater species richness (+8.4%), taller maximum height (+21%), reduced coverage of sun-loving plants (−71%), and less dead biomass accumulation (−26%), from shade-driven effects. …”
Get full text

Both light and soil moisture affect the rhizosphere microecology in two oak species by Jinshuo Lian, Keke Cai, Aijing Yin, Yuan Yuan, Xinna Zhang, Chengyang Xu

“…To elucidate the response of the rhizosphere microecology of Quercus dentata and Quercus variabilis seedlings to water and light conditions, and to clarify how plants modulate the structure and function of rhizosphere microbial communities under drought stress, we conducted 12 water-light gradient control experiments. …”
Get full text

Hydrothermal synthesis of a nickel-oxide-infused orange peel nanobiocomposite for enhanced heavy metal removal from mining wastewater by Jacques Romain Njimou, Velma Fai, Mary Tamwa Sieugaing, Djimongbaye Nguenamadje, John Godwin, Oben Bessem Genola, Guy Bertrand Noumi, Bankim Chandra Tripathy

“…Characterization techniques such as FTIR, XRD, SEM, and EDS reveal a highly porous morphology due to NiO nanoparticle integration within the OP matrix, a structure that provides numerous active sites for adsorption. …”
Get full text

Refinement of a meaning-centered counseling program for Chinese patients with advanced cancer: integrating cultural adaptation and implementation science approaches by Florence Lui, Qingyi Zhang, George Chengxi Bao, Bharat Narang, Ruo Yan Chen, Yunshan Niu, Jennifer Leng, William Breitbart

“…Methods Fifteen purposively sampled mental health professionals who work with Chinese cancer patients completed surveys providing Likert-scale ratings on acceptability and comprehensibility of MCP-Ch content (guided by the EVM) and pre-implementation factors (guided by PRISM), followed by semi-structured interviews. Survey data were descriptively summarized and linked to qualitative interview data. …”
Get full text

Double degree programs and education for sustainable development implementation: Experience of Ukrainian and UK universities cooperation in wartime by Iryna Skliar, Mykola Kostel’, Olena Melnyk, Kseniia Bliumska-Danko

“…This study employed semi-structured interviews. Interviewees were selected from the academic staff of five of the six Ukrainian universities involved in DDPs. …”
Get full text

Patient centered medication treatment for opioid use disorder in rural Vermont: a qualitative study by Emily G. Hichborn, Owen B. Murray, Eilis I. Murphy, Tess E. Gallant, Sarah K. Moore, Bethany M. McLeman, John Saroyan, Anthony Folland, Megan Mitchell, Lisa A. Marsch

“…Methods Fifteen semi-structured telephone interviews were conducted from August through November of 2021 regarding patient experiences receiving MOUD in 13 Vermont Hub and Spoke clinics. …”
Get full text

Hybridization-based discovery of novel quinazoline-2-indolinone derivatives as potent and selective PI3Kα inhibitors by Changqun Liu, Yuening Cao, Yi Zuo, Chaozheng Zhang, Senmiao Ren, Xin Zhang, Chuanqi Wang, Yingjie Zeng, Jie Ling, Yilan Liu, Zixian Chen, Xiujun Cao, Zhengzhi Wu, Chuantao Zhang, Jun Lu

“…Methods: 26 quinazoline-2-indolinone derivatives were obtained by molecular hybridization, and their structure–activity relationship was analyzed by MTT, in vitro kinase activity and molecular docking. …”
Get full text

Combining genotyping approaches improves resolution for association mapping: a case study in tropical maize under water stress conditions by Fernanda Carla Ferreira de Pontes, Ingrid Pinheiro Machado, Maria Valnice de Souza Silveira, Antônio Lucas Aguiar Lobo, Felipe Sabadin, Roberto Fritsche-Neto, Júlio César DoVale

“…Recent studies show SNP-Array, GBS, and Mock yield similar results for population structure, heterotic groups definition, tester selection, and genomic hybrid prediction. …”
Get full text

Factors associated with perceived changes in physical activity and sedentary behavior in the Brazilian university community during the COVID-19 pandemic by Marcos Cezar Pitombo da Silva Junior, Enaiane Cristina Menezes, Sand Araújo Tenório, Sueyla Ferreira da Silva dos Santos, Thiago Ferreira de Sousa, Luiz Rodrigo Augustemak de Lima

“…Methods: It is an observational, cross-sectional, multicenter study conducted with the academic community of higher education institutions in Brazil. A structured and validated questionnaire was utilized, and multinomial logistic regression was applied with a 95% confidence interval. …”
Get full text

Risk Values of Weight and Body Mass Index for Chest Wall Thickness in Patients Requiring Needle Thoracostomy Decompression by Chia-Hung Hsu, Tzu-Yin Lin, Ju-Chi Ou, Jiann Ruey Ong, Hon-Ping Ma

“…A catheter of suitable length may not be available immediately or the muscle structure of the chest wall may be modified in pneumothorax. …”
Get full text

Values and professional identity of student-age population by I. A. Koch, В. A. Orlov

“…The main empirical methods of sociological research involve observation and mass questionnaire survey of students of Ural State Mining University (Ekaterinburg) and Ural Institute of Management of the Russian Presidential Academy of National Economy and Public Administration (Ekaterinburg). 606 full-time students were interviewed.Results and scientific novelty. The value structure and professional preferences of young people transformed by external causes, their recognition of the acquired profession and their role in the implementation of their own life plans were analysed in a comprehensive manner. …”
Get full text

Discoloration and Degradation of Bamboo under Ultraviolet Radiation by Haixia Yu, Shengliang He, Wenfu Zhang, Mengyao Zhan, Xiaowei Zhuang, Jin Wang, Wenji Yu

“…Particularly, 2,6-dimethylbenzoquinone which contained a cyclohexenedione structure without benzene rings, was more chemically stable than other conjugated double bonds with benzene rings, and was supposed to be the final product (chromogenic group) during bamboo photodegradation. …”
Get full text

Assessment of MPOX infection-related knowledge levels, concerns, and associated factors: a community-based cross-sectional study by Mehmet Emin Arayici, Suleyman Dolu, Hasan Ozdek Sayilir, Hatice Simsek, Sükran Kose

“…Socio-demographic data were collected, and MPOX knowledge and concerns were assessed using a structured data form. To assess knowledge levels regarding MPOX, 15 questions were defined with 1 point given for each correct answer, and these questions were then categorized as high knowledge (≥ 10 correct answers) and low knowledge (< 10 correct answers). …”
Get full text

Influence of Abutment Screw-Tightening Methods on the Screw Joint: Immediate and Long-Term Stability by Manlin Sun, Yusen Shui, Yuqiang Zhang, Ruiyang Ma, Yuwei Zhao, Hongyu Chen, Ping Yu, Zhi Li, Tingting Wu, Haiyang Yu

“…The operating time of method A was much longer than those of methods B and C (P<0.001). The structural integrity disruption of the screw thread was observed according to the SEM results in all postloading groups. …”
Get full text