Peptide Design for Enhanced Anti-Melanogenesis: Optimizing Molecular Weight, Polarity, and Cyclization by Putri SA, Maharani R, Maksum IP, Siahaan TJ

“…Cyclization of peptides enhances their structural stability, serum resistance, and binding affinity while reducing toxicity. …”
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A Personalised Optimising Level Adaptation (OLA) Difficulty Algorithm for Scenario Simulations in Professional VR Simulators by Marcin Wolański Robert, Karol Jędrasiak

“…Each scenario was divided into ten blocks of varying difficulty (easy, medium, difficult), dynamically adjusted based on the user's performance. This structure enables rapid adaptation, making it particularly beneficial for fire and rescue training, where realistic, yet scalable, scenario complexity is critical to preparing for unpredictable conditions in the field. …”
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

“…Shuhan Liu,1– 3 Haisong Li,4 Shiwen Xi,1,2 Yuning Zhang,1,2,* Tianmeng Sun1,2,5,6,* 1Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, Institute of Immunology, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 2National-Local Joint Engineering Laboratory of Animal Models for Human Diseases, Changchun, People’s Republic of China; 3Cancer Center, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 4Department of Neurosurgery, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 5International Center of Future Science, Jilin University, Changchun, People’s Republic of China; 6State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianmeng Sun; Yuning Zhang, The First Hospital of Jilin University, 71 Xinmin St, Changchun, Jilin, People’s Republic of China, Email tsun41@jlu.edu.cn; zhangyuning@jlu.edu.cnAbstract: Given the complexity of the central nervous system (CNS) and the diversity of neurological conditions, the increasing prevalence of neurological disorders poses a significant challenge to modern medicine. …”
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Does Democracy Still Fall? A Bibliometric Analysis Two Decade 2004-2024 by Henky Fernando, Yuniar Galuh Larasati, Julia Magdalena Wuysang, Putri Rahmah Nur Hakim, Novita Cahyani

“…However, these studies have not been able to intervene and respond to the structural, cultural, and even spiritual challenges that underlie the difficulty of implementing a democratic political system in the era of globalization. …”
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Amphetamine use as a predictor of cardiovascular and cerebrovascular mortality and morbidity: a longitudinal cohort study of criminal justice clients by Ada Åhman, Jonas Berge, Anders Håkansson

“…In addition, in a criminal justice system, illicit drug use and psychiatric comorbidity is common, whereas structured treatment and follow-up is uncommon, and stimulant use is common in this setting. …”
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Spatial Patterns of Taxonomic, Functional, and Phylogenetic Diversity of Mammals in Southern Mexico by Cintia Natalia Martín‐Regalado, Mario C. Lavariega, Miguel Briones‐Salas

“…As observed globally, functional diversity was higher in temperate areas; however, redundancy was not found in tropical ecosystems but rather in semiarid ones, suggesting that environmental filtering plays an important role in structuring communities. Contrary to expectations, phylogenetic diversity increased in tropical ecosystems, where dispersal events allow species to accumulate through invasion processes. …”
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TIPIFICACIÓN MORFOLÓGICA DE CURSOS PRINCIPALES. CUENCA DEL ARROYO EL NEGRO, SISTEMA DE VENTANIA, ARGENTINA by Alicia M. Campo, Verónica Gil, Guadalupe Ybarra Alcaráz, Antonela Volonté

“…Morphology varies according to the structure and the drainage network. Fluvial systems typification classifies and characterize rivers in order to provide substantial information about every section. …”
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The impact of export market orientation on SME market performance: Exploring the moderating effect of government policy and the mediating effect of information access by Sunday Noya, Stefanus Yufra M. Taneo, Melany

“…The collected data were then analyzed using structural equation modeling (SEM) techniques. The findings demonstrate that export market orientation significantly boosts SME market performance (path coefficient = 0.512, p < 0.001), highlighting its critical role in fostering customer-oriented practices and adaptive marketing strategies. …”
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TAXATION OF AGRICULTURAL ACTIVITY IN POLAND: THE CURRENT STATE AND FUTURE PROSPECTS by Marian Podstawka, Łukasz Podstawka

“…Therefore, when a new income tax structure is introduced, its rate should not exceed 10%. …”
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Increase in blood pressure precedes distress behavior in nursing home residents with dementia. by Kenneth S Boockvar, Tianwen Huan, Kimberly Curyto, Sei Lee, Orna Intrator

“…Each individual with a BP reading and a DBD incident according to a structured behavior note on a calendar day (DBD group) was compared with an individual with a BP reading but without a DBD incident on that same day (comparison group). …”
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The Application of Numerical Simulation in Debris Flow Disaster Early Warning: A Case Study of Shiyang Gully, China by Hao Zheng, Lanlan Guo, Jifu Liu, Bin Chen, Lianyou Liu

“…Simulation results showed that cumulative rainfall exceeding 90 mm or rainfall intensity surpassing 200 mm/8 h significantly increases debris flow depth, impact force, and affected areas, leading to severe structural damage. Expanding the rainfall range to the entire basin further amplifies disaster risks, increasing both inundation depth and exposed elements. …”
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A multi-strain human skin microbiome model provides a testbed for disease modeling by Angela L. Maloney, Tyler Crawford, Jordan Hurlbut, Monica Martinez, Thomas J. Mulhern, Elizabeth L. Wiellette, Else M. Vedula, Vidhya Vijayakumar

“…Skin cells formed a complex tissue structure over two weeks and maintained stable or increasing TEER after 7 days of co-culture with the microbial consortium. …”
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Workforce outcomes among substance use peer supports and their contextual determinants: A scoping review protocol. by Justin S Bell, Tina Griffin, Sierra Castedo de Martell, Emma Sophia Kay, Mary Hawk, Michelle Hudson, Bradley Ray, Dennis P Watson

“…; 2) What is known about how the structure of work impacts these outcomes?; and 3) How do these outcomes differ by service setting type?…”
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Temporal shifts in dengue epidemic in Guangdong Province before and during the COVID-19 pandemic: a Bayesian model study from 2012 to 2022. by Jiaqing Xu, Xiaohua Tan, Yi Quan, Dexin Gong, Hui Deng, Jianguo Zhao, Xing Huang, Yingtao Zhang, Zhoupeng Ren, Zuhua Rong, Weilin Zeng, Xing Li, Wenyuan Zheng, Shu Xiao, Jianpeng Xiao, Meng Zhang

“…Based on the counterfactual framework, we constructed the Bayesian structural time series (BSTS) model to capture the epidemic trends of dengue.…”
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Principles for increasing equity in WASH research: understanding barriers faced by LMIC WASH researchers by J'Anna-Mare Lue, Salamata Bah, Kaelah Grant, Justine Lee, Leila Nzekele, James B. Tidwell

“…Five interviews were conducted with key WASH research funders to assess perceptions of obstacles faced by LMIC researchers, successes achieved and challenges faced by these organisations when working towards more equitable research processes within the WASH sector.Results The results were analysed using an emergent framework that categorised experiences based on power differentials and abuse of power; structural barriers due to organisational policies; institutional and individual indifference; othering speech, action and practices; and context-specific discrimination. …”
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The Mutual Inhibition of FoxO1 and SREBP-1c Regulated the Progression of Hepatoblastoma by Regulating Fatty Acid Metabolism by Yu Hu, Hongyan Zai, Wei Jiang, Zhenglin Ou, Yuanbing Yao, Qin Zhu

“…After the knockdown of the SREBP-1c gene, the structure of tumor cells was deformed. Conclusion. …”
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The Relevance of Cognitive and Affective Factors to Explain the Acceptance of Blockchain Use: The Case of Loyalty Programmes by Mar Souto-Romero, Mario Arias-Oliva, Jorge de Andrés-Sánchez, Miguel Llorens-Marín

“…A partial least squares-structural equation modelling analysis suggests that, to explain the expected response of BEHAV, only the positive relationships of the cognitive constructs with the response variable are significant. …”
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How I experienced tele-intervention: Qualitative insights from persons who stutter by Raadhiyah Hoosain, Shabnam Abdoola, Esedra Krüger, Bhavani Pillay

“…Objectives: The study aims to explore clients’ experiences with tele-intervention for stuttering therapy, and to provide recommendations to improve service delivery. Method: Semi-structured interviews were conducted with 11 persons who stutter (PWS) recruited through purposive sampling. …”
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Effectiveness of deliberate practices versus conventional lecture in trauma training for medical students by Suksan Kanoksin, Bhapapak Na Songkhla, Amarit Tansawet, Issaree Laopeamthong, Pakkapol Sukhvibul, Suphakarn Techapongsatorn

“…The primary outcome was the students’ scores on the Objective Structured Clinical Examination (OSCE), whereas the secondary outcome was their overall grades. …”
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Ethnicity-specific distribution of <em>TRPM8</em> gene variants in Eurasian populations: signs of selection by T. A. Potapova, A. G. Romashchenko, N. S. Yudin, M. I. Voevoda

“…Apparently in the process of human colonization of Eurasia, minor alleles of these SNPs diverged depending on rs7593557 structure in exon 11. We analyzed sequences of five TRPM8 mRNA isoforms extracted by researchers from different tissues. …”
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