Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain by Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg

“…Nearly all evidence of genome structural variation in human brains comes from studies detecting changes in single cells which were interpreted as derived from independent, isolated mutational events. …”
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Exposure of Apis mellifera (Hymenoptera: Apidae) colonies to imidacloprid impairs larval development, promotes oxidative stress in pupae, and induces changes in the midgut of adult... by Daiani Rodrigues Moreira, Tuan Henrique Smielevski de Souza, Douglas Galhardo, Cinthia Leão Figueira, Samara Calvi Baulli, Breno Gabriel da Silva, Francieli das Chagas, José Washington Santos Oliveira, Jean Samel Rocha, Angélica de Souza Khatlab, Eliane Gasparino, Vagner de Alencar Arnaut de Toledo, Adriana Aparecida Sinópolis Gigliolli, Maria Claudia Colla Ruvolo-Takasusuki

“…The midgut of adult bees contaminated with IMDCF showed only structural remnants of the peritrophic membrane and absence of regenerative cell nests. …”
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A novel TGFBR2 mutation causes Loeys-Dietz syndrome in a Chinese infant: A case report by Xin Liu, Kaiqing Liu, Lifu Hu, Zixiao Liu, Xinhua Liu, Jiantao Wang

“…Molecular dynamics simulations and in vitro cell experiments further analyzed the structural changes and functional abnormalities of the variation. …”
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Effect of recycling on the time- and temperature-dependent mechanical properties of PP/MWCNT composite liner materials by Attila Bata, Péter Gerse, Krisztián Kun, Emese Slezák, Ferenc Ronkay

“…These preliminary findings reveal that recycled PP/MWCNT composites can provide structural integrity, making them suitable for high-performance applications like hydrogen storage. …”
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Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives by Yan Feng, Zengqiang Li, Xiangjun Kong, Aziz Khan, Najeeb Ullah, Xin Zhang

“…These strategies included changes in cellular membranes and chloroplast structure, regulating cold signals related to phytohormones and plant growth regulators (ABA, JA, GA, IAA, SA, BR, ET, CTK, and MET), reactive oxygen species (ROS), protein kinases, and inorganic ions. …”
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Talking with pregnant women exposed to cannabis use after cannabis legalization: Experiences of professionals working in Québec's social and healthcare system by Karen A. Dominguez-Cancino, Rose Chabot, Yolaine Frossard de Saugy, Kristelle Alunni-Menichini, Lysiane Robidoux-Léonard, Genève Guilbert-Gauthier, Karine Bertrand, Christophe Huỳnh, Pablo Martínez, Helen-Maria Vasiliadis, Nadia L'Espérance, Victoria Massamba, Julie Loslier, José Ignacio Nazif-Munoz

“…Methods: This is a qualitative study using semi-structured interviews. Purposeful sampling was employed to recruit 19 professionals, including physicians, nurses, psychologists, and social workers. …”
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Melatonin Ameliorates Organellar Calcium Homeostasis, Improving Endoplasmic Reticulum Stress-Mediated Apoptosis in the Vastus Lateralis Muscle of Both Sexes of Obese Diabetic Rats by Diego Salagre, Miguel Navarro-Alarcón, Luis Gerardo González, Mohamed A. Elrayess, Marina Villalón-Mir, Rocío Haro-López, Ahmad Agil

“…Our previous research showed that melatonin raises intracellular calcium and preserves muscle structure by enhancing mitochondrial function in obese diabetic rats. …”
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Influences on safety of intrapartum electronic fetal heart rate monitoring practices: a scoping review by Cathy Winter, Mary Dixon-Woods, Isla Kuhn, Guillaume Lamé, Elisa Liberati, Jenni Burt, Sarah Kelly, Alice Egerton, Tim J Draycott, Harry Kyriacou, Kathryn Jones, Harry Dunn, Xueying Nancy Zheng, Zi Qi Kok

“…Findings were synthesised using a best-fit framework approach, structured using an existing 19-domain framework of contributory factors for patient safety incidents in hospitals.Results 142 articles and 14 reports were included. …”
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Role of acute respiratory diseases in pathogenesis of distal limb infections in cattle by A. D. Alekseev, O. G. Petrova, M. I. Barashkin, I. M. Milshtein, V. D. Moskvin

“…Low molecular weight circulating immune complexes settle in various organs and tissues of the body, lead to inflammation and damage the normal tissue structure. Most frequently, immune complexes affect the endothelium of blood vessels, renal glomeruli and joints. …”
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How to transform cultivated land protection on the Northeast Tibetan Plateau？ A multifunctional path exploration by Rongrong Ma, Yuhan Huang, Wei Zhou, Jun Ren, Hongyu Wang, Zeyu Shi, Juan Wang

“…Correlation analysis and a coupled coordination degree model are used to understand the intrinsic structural characteristics that impact the multifunctionality of CLs. …”
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Streaming Torque with Turbulent Diffusion by Qiang Hou, Cong Yu

“…The dust diffusion will smooth the short-wavelength structure of the the quasi-drift mode and split it into two predominant D-drift modes with opposite directions. …”
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A comprehensive review of AI-based collagen valorization: Recent trends, innovations in extraction, and applications by Arthi Srinivasan, Arun Gupta, Vigneswaran Narayanamurthy

“…Collagen, constituting approximately 30 % of total body proteins, is a critical structural protein with extensive applications in biomedical, cosmetic, and food industries. …”
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Long-term Spectral Monitoring of Active Asteroid (6478) Gault: Implications for the H Chondrite Parent Body by Adam Battle, Vishnu Reddy, Juan A. Sanchez, Neil Pearson, Benjamin N. L. Sharkey, Theodore Kareta

“…The low-level thermal metamorphism interpretation of Gault’s surface suggests that it formed from the outermost portion of the progenitor of the Phocaea family, assuming an “onion shell’ structure, which was catastrophically disrupted 1.2 Gyr ago. …”
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Precision Adverse Drug Reactions Prediction with Heterogeneous Graph Neural Network by Yang Gao, Xiang Zhang, Zhongquan Sun, Payal Chandak, Jiajun Bu, Haishuai Wang

“…Next, a GNN‐based model is utilized to learn latent representations of the patient nodes and facilitate the propagation of information throughout the graph structure. By employing patient embeddings that consider their diseases and drugs, potential ADRs can be accurately predicted. …”
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Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study by Wenjing Cao, Zefu Yang, Liumei Mo, Zhenhao Liu, Jiawei Wang, Zhenhong Zhang, Kui Wang, Wei Pan

“…BackgroundHeart failure (HF) is a clinical syndrome resulting from structural damage or dysfunction of the heart. Previous investigations have highlighted the critical involvement of immune cells in the progression of heart failure, with distinct roles attributed to different types of immune cells. …”
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Blood Glucose Lowering Efficacy of Strawberry Extracts Rich in Ellagitannins with Different Degree of Polymerization in Rats by Juśkiewicz Jerzy, Jurgonski Adam, Kołodziejczyk Krzysztof, Kosmala Monika, Milala Joanna, Zduńczyk Zenon, Fotschki Bartosz, Żary-Sikorska Ewa

“…The results clearly showed that the separate mechanisms (glucose transport across the intestine, intestinal mucosal disaccharidases inhibition activity, pancreatic α-amylase inhibitory activity) leading to decreased postprandial glycaemia upon dietary administration of strawberry ellagitannins largely depended on their chemical structure, i.e. degree of polymerization.…”
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Two novel entomopathogenic fungal species of Lecanicillium isolated from soil in China by Tongyi Liu, Wei Chen, Yanhong Tang, Fen Liu, Liyan Yao, Qiongbo Hu, Ke Zhang, Qunfang Weng

“…They differ from known closely related species primarily in sporulation structure, conidia and colony morphological characteristics, and sequence variations in the LSU, SSU, ITS, and TEF gene regions of the ribosomal DNA. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Mechanistic insights were further gained through DNA methylation profiling and chromatin structure analysis. Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. …”
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Using stone dust as an improvement material for cement gravel column by Raksiri Sukkarak, Pornkasem Jongpradist, Panich Voottipruex, Pitthaya Jamsawang, Suraparb Keawsawasvong, Teerawut Pansuwannakun, Ittipon Meepon

“…A cement gravel (CG) column was employed for ground improvement in foundation engineering, offering increased load-bearing capacity and structure stability. This research explores the feasibility of incorporating stone dust into cement gravel columns to enhance their mechanical properties and sustainability profile. …”
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Three local plants adapt to ecological restoration of abandoned lead-zinc mines through assembly of rhizosphere bacterial communities by Wei Gao, Shuyi Chen, Xin Yu, Sumin Chen, Caijing Wan, Ying Wang, Peng Wu, Qiang Li

“…Following the planting of the three types of ecologically restored plants, the soil bacterial community structure partially recovered. In addition, different plants have been found to have different functions in the lead-zinc ecological restoration process, including iron complex transport system-permitting proteins and ATP binding cassettes.DiscussionThis study confirms for the first time that plants adapt to the remediation process of abandoned lead-zinc mines by non-randomly assembling rhizosphere bacterial communities and functions, providing a reference for screening microbial remediation bacterial resources and plant microbe joint bioremediation strategies for lead-zinc mines.…”
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