Distal protein-protein interactions contribute to nirmatrelvir resistance by Eric M. Lewandowski, Xiujun Zhang, Haozhou Tan, Aiden Jaskolka-Brown, Navita Kohaal, Aliaksandra Frazier, Jesper J. Madsen, Lian M. C. Jacobs, Jun Wang, Yu Chen

“…Particularly, L50F and other non-active site mutations can enhance the Mpro dimer-dimer interactions and help place the nsp5-6 substrate at the enzyme catalytic center. The structural and enzymatic activity data of Mpro L50F, L50F/E166A/L167F, and others underscore the importance of considering the whole substrate protein in studying Mpro and substrate interactions, and offers important insights into Mpro function, resistance development, and inhibitor design.…”
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Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (<i>Z</i>)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5<i>H</i>)-one Analogs: In Vitro and In Vivo Insight... by Hee Jin Jung, Hye Jin Kim, Hyeon Seo Park, Hye Soo Park, Jeongin Ko, Dahye Yoon, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon

“…Fifteen compounds (<b>1</b>–<b>15</b>) constructed on a hybrid structure combining a β-phenyl-α,β-unsaturated carbonyl template and a 2-aminothiazol-4(5<i>H</i>)-one scaffold were designed and synthesized as potential novel anti-tyrosinase substances. …”
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Culinary Arts: A Motivator Towards Community-Based Festival Attendance and Sustainability by Ibraheem Kukoyi, Abioye Adedipe, Tajudeen Yusuf, Opeyemi Ijaya

“…Convenience sampling method was further used to select 100 festivals attendees, making a total of 150 respondents and a structured close-ended questionnaire was administered for data gathering. …”
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Electrochemically-driven solid oxide tubular membrane reactor for efficient separation of oxygen and argon by Yuanhui Tang, Yutao Hu, Sisi Wen, Song Lei, Yakai Lin, Li Ding, Haihui Wang

“…The tubular membrane reactor featured an anode/electrolyte/cathode sandwich structure, offering a compact design particularly suited for gas separation. …”
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Variabilities in Retinal Hemodynamics Across the Menstrual Cycle in Healthy Women Identified Using Optical Coherence Tomography Angiography by Vlad Constantin Donica, Alexandra Lori Donica, Irina Andreea Pavel, Ciprian Danielescu, Anisia Iuliana Alexa, Camelia Margareta Bogdănici

“…The present study attempts to evaluate retinal and choroidal vascular and structural changes in healthy female subjects over the course of a menstrual cycle using OCT-A. …”
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Autoencoder Reconstruction of Cosmological Microlensing Magnification Maps by Somayeh Khakpash, Federica B. Bianco, Georgios Vernardos, Gregory Dobler, Charles Keeton

“…Enhanced modeling of microlensing variations in light curves of strongly lensed quasars improves measurements of cosmological time delays, the Hubble Constant, and quasar structure. Traditional methods for modeling extragalactic microlensing rely on computationally expensive magnification map generation. …”
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Effect of ultrasonic amplitude on microstructure and properties of wire arc additive manufactured ultra-high strength steel deposited metal by Tianli Zhang, Weifeng Li, Wen Wu, Lianyong Xu, Donghai Hu, Geng Chen, Wei Li, Erika Hodúlová

“…The nucleation sites of acicular ferrite are further increased, the multiphase segmentation structure is more obvious, and the impact toughness is further improved. …”
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MXenes in biosensing: Enhancing sensitivity and flexibility – A review of properties, applications, and future directions by Ali Mohammad Amani, Lobat Tayebi, Ehsan Vafa, Alireza Jahanbin, Milad Abbasi, Ahmad Vaez, Hesam Kamyab, Lalitha Gnanasekaran, Shreeshivadasan Chelliapan

“…In the context of biosensing, MXenes are particularly noteworthy because of their layered structure and composition, which render them suitable for both electrochemical and optical biosensors. …”
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Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines by Wilfredo Hernández, Juan Paz, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Jorge Manzur, Lothar Hennig, Joachim Sieler, Steffen Blaurock, Lothar Beyer

“…The palladium(II) bis-chelate complexes of the type [Pd(TSC1-5)2] (6–10), with their corresponding ligands 4-phenyl-1-(acetone)-thiosemicarbazone, HTSC1 (1), 4-phenyl-1-(2′-chloro-benzaldehyde)-thiosemicarbazone, HTSC2 (2), 4-phenyl-1-(3′-hydroxy-benzaldehyde)-thiosemicarbazone, HTSC3 (3), 4-phenyl-1-(2′-naphthaldehyde)-thiosemicarbazone, HTSC4 (4), and 4-phenyl-1-(1′-nitro-2′-naphthaldehyde)-thiosemicarbazone, HTSC5 (5), were synthesized and characterized by elemental analysis and spectroscopic techniques (IR and 1H- and 13C-NMR). The molecular structure of HTSC3, HTSC4, and [Pd(TSC1)2] (6) have been determined by single crystal X-ray crystallography. …”
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Dynamics and diversity of vaginal microbiota in bacterial vaginosis among Thai patients treated with metronidazole by Auttawit Sirichoat, Pranom Buppasiri, Kiatichai Faksri, Viraphong Lulitanond

“…Conclusions: This study provides valuable insights into the structure and dynamics of the VMB in Thai women with BV before and after treatment, offering potential markers for predicting treatment outcomes.…”
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Together throughout the year: seasonal patterns of bacterial and eukaryotic microbial communities in a macrotidal estuary by Vincent Hervé, Jérôme Morelle, Josie Lambourdière, Pascal Jean Lopez, Pascal Claquin

“…To date, the taxonomy of the microbial diversity present in this anthropized estuary remains elusive and the drivers of the microbial community structure are still unknown. Results The metabarcoding analysis of 147 samples revealed both a high bacterial and eukaryotic diversity, dominated by Proteobacteria, Bacteriodota, Actinobacteriota and Bacillariophyta, Spirotrichea, Dinophyceae, respectively. …”
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Evidence for a Specific Diabetic Cardiomyopathy: An Observational Retrospective Echocardiographic Study in 656 Asymptomatic Type 2 Diabetic Patients by Isabelle Pham, Emmanuel Cosson, Minh Tuan Nguyen, Isabela Banu, Isabelle Genevois, Patricia Poignard, Paul Valensi

“…SMI, obesity, and poor glycemic control contribute to structural and functional LV abnormalities.…”
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Silver-blend hydroxyapatite bio-ceramics for enhanced photocatalytic degradation of methylene blue by Manoj V. Junnarkar, Prateek V. Sawant, Mahadev A. Parekar, Avadhut V. Kardile, Ashish B. Thorat, Ramakant P. Joshi, Ravindra U. Mene

“…X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscope (SEM)/energy-dispersive X-ray spectroscopy (EDS) are used to analyze the structural, functional, morphological, and elemental properties of the samples. …”
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Service innovation in telecommunication: The path to customer loyalty through enhanced customer satisfaction by Manoj Kumar Chaudhary, Dinesh Mani Ghimire, Madan Dhungana, Rajesh Kumar Chaudhary, Madhav Adhikari, Shubhechchha Thapa

“…Based on a sample of 245 telecom customers, this study investigates how innovative service offerings lead to higher satisfaction levels and, in turn, greater customer loyalty. This study uses structural equation modeling (SEM) and a quantitative research approach to examine the association between customer satisfaction, customer loyalty, and service innovation in Nepal’s telecom industry. …”
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Experience of Kenyan researchers and policy-makers with knowledge translation during COVID-19: a qualitative interview study by Edwine Barasa, Benjamin Tsofa, Mike English, Sassy Molyneux, Dorcas Mwikali Kamuya, Fatuma Hassan Guleid, Alex Njeru, Joy Kiptim, Emelda Okiro, David Kariuki

“…Data were collected from March 2021 to August 2021.Analysis A thematic analysis approach was adopted using a predetermined framework to develop a coding structure consisting of the core thematic areas. Any other theme that emerged in the coding process was included.Results Both groups reported that the KT activities increased evidence availability and accessibility, enhanced policy-makers’ motivation to use evidence, improved capacity to use research evidence and strengthened relationships. …”
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Additive-manufactured ceramics for dental restorations: a systematic review on mechanical perspective by Yuqing Lu, Anouk van Steenoven, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Li Wang, Li Wang, Cornelis J. Kleverlaan, Albert J. Feilzer, Albert J. Feilzer

“…This systematic review aimed to update the latest advances in additive manufacturing of restorative ceramics with a focus on their mechanical properties.MethodsThis systematic review was structured using the 5-step methodology based on the research question: what are the mechanical properties of additive-manufactured restorative ceramics in comparison with subtractive manufacturing? …”
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Foliar application of humic liquid extract from vermicompost improves garlic (Allium sativum L.) production and fruit quality by D. M. Balmori, C. Y. A. Domínguez, C. R. Carreras, S. M. Rebatos, L. B. P. Farías, F. G. Izquierdo, R. L. L. Berbara, Andrés Calderín García

“…At 125 days after planting, the plants were collected, and growth and production parameters were determined: quantity of garlic cloves, fresh and dry bulb, diameter of garlic cloves and bulb, as well as parameters of fruit quality including caliber, firmness, acidity, brix, pungency, carbohydrate and protein contents. Results The structure of HS in HEVC is composed mainly of carbohydrates and peptides as well as lignin fragments, explaining the stimulus effects on plant metabolism. …”
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Dynamic recrystallization and mechanical behavior of Mg alloy AZ31: Constraints from tensile tests with in-situ EBSD analysis by Boissonneau, Gaëtan, Tommasi, Andréa, Barou, Fabrice, Lopez-Sanchez, Marco Antonio, Montagnat, Maurine

“…This long incubation period is followed by acceleration of DRX, with faster grain boundary migration allowing for development of a DRX-necklace structure, whose spatial heterogeneity controls the final strain localization at strains > 60%. …”
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Perspectives of push-pull-mooring effects on a desire for switching to alternative crops among tobacco farmers in Thailand: A qualitative study by Chakkraphan Phetphum, Artittaya Wangwonsin, Atchara Prajongjeep, Saksin Simsin

“…This study aims to provide insight into why tobacco farmers desire to switch to alternative crops and the support required for a successful transition. Methods Semi-structured interviews were conducted with 34 tobacco farmers expressing a desire to transition to other crops in two communities in Thailand. …”
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Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol by Hanna Maria Dragoș, Adina Stan, Livia Livinț Popa, Roxana Pintican, Diana Feier, Nicu Cătălin Drăghici, Dragoș-Cătălin Jianu, Diana Chira, Ștefan Strilciuc, Dafin F. Mureșanu

“…Brain reserve refers to the brain’s structural capacity to compensate for damage, with markers like hippocampal atrophy and white matter lesions indicating reduced reserve. …”
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