Engineering hydrophobicity and manufacturability for optimized biparatopic antibody–drug conjugates targeting c-MET by Andreas Evers, Simon Krah, Deniz Demir, Ramona Gaa, Desislava Elter, Christian Schroeter, Stefan Zielonka, Nicolas Rasche, Julia Dotterweich, Christine Knuehl, Achim Doerner

“…The resulting biparatopic anti-c-MET ADCs were comparably active on c-MET expressing tumor cell lines as REGN5093 exatecan DAR6 ADC. Structural molecular modeling of paratope combinations for preferential inter-target binding combined with protein engineering for manufacturability yielded deep insights into the capabilities of rational and library approaches. …”
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Multimodal Autism Spectrum Disorder Method Using GCN With Dual Transformers by Tianming Song, Zhe Ren, Jian Zhang, Yawei Qu, Yingying Cui, Zhengda Liang

“…Co-training is introduced to simultaneously harness both functional magnetic resonance imaging and structural magnetic resonance imaging data, improving the model’s capacity to generalize across different datasets. …”
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A Multibeam Solar Grid Antenna Integrated With Monocrystalline Silicon Solar Cell by Fuwei Wang, Xuechen Zhang, Rong Sun, Bokai Ding, Ke Li, Chen He

“…Meanwhile, the grid-like structure of the antenna ensures good optical transmission, allowing it to be positioned above the solar panel without significantly affecting the performance of the solar cell. …”
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Multi-Step Forecasting of Chlorophyll Concentration with Multi-Attention Collaborative Network by Yingying Jin, Feng Zhang, Xia Wang, Lei Wang, Kuo Chen, Liangyu Chen, Yutao Qin, Ping Wu

“…In order to overcome these obstacles, we propose a Multi-Attention Collaborative Network (MACN)-based triangle-structured prediction system. In particular, the MACN consists of two branch networks, with one named <b>NP-net</b>, focusing on non-predictive variables, and the other named <b>T-net</b>, applied to the target variable. …”
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Microscopic damage evolution and physical–mechanical behavior of high-temperature red sandstone under varying heating and cooling durations by Mingze Qin, Yue Su, Xiaolan Wang, Huawu Niu, Yifan Zhang, Dongxu Zhang, Nan Qin

“…The findings show that elevated temperatures and prolonged heating significantly alter the microstructure and composition of red sandstone, including pore formation, void development, and structural modifications. Heating induces cracking, voids, and chemical reactions, with extended exposure leading to changes in feldspar minerals (K/Ca/Na). …”
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Short-Time High-Oxygen Pre-Treatment Delays Lignification of Loquat (<i>Eriobotrya japonica</i> Lindl.) During Low-Temperature Storage by Runlei Kou, Mengfei Peng, Jiaxuan Zheng, Shuangdi Hou, Linyuan Ma, Xia Liu

“…Meanwhile, 80% SHOP improved the antioxidant enzyme system and maintained the structural integrity of the cells. Furthermore, SHOP retained the color and suppressed decay and weight loss and the decline in the soluble solids content (SSC) and titratable acidity (TA). …”
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COPPER HEXACYANOFERRATE (II): SYNTHESIS, CHARACTERIZATION, AND CESIUM, STRONTIUM ADSORBENT APPLICATION by Dinh Trung Nguyen, Vu Tram Anh Le, Dong Phuong Truong, Thi Dan Thy Kieu, Tran Thuy Hong Nguyen, Ping Ning, Thi Huong Giang Duong, Kim Dan Ho

“…Copper hexacyanoferrate, Cu13[Fe(CN)6]14.(2K).10H2O, has a cubic structure (space group F-43m) in the range of 10-30 nm and a Brunauer-Emmett-Teller (BET) surface area of 462.42 m2/g. …”
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Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis by Xinyan Hao, Yucheng Tang, Wenjie Xu, Ming Wang, Jiayi Liu, Yongjiang Li, Jun He, Yanjin Peng, Pengcheng Sun, Dehua Liao, Xiongbin Hu, Tiantian Tang, Min Zhou, Ruyue Han, Jiemin Wang, João Conde, Daxiong Xiang, Junyong Wu

“…For the effective delivery of CDDP, the CDDP-polyphenol nanocomplexes were prepared, and catalase and copper ions were incorporated to fortify structural integrity, enhance glutathione (GSH) responsiveness, and ameliorate tumor hypoxia. …”
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Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway by Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale

“…The angiopoietin-like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins structurally related to factors modulating angiogenesis known as angiopoietins. …”
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Current Control in Field-Excited Flux Switching Machines: No-Load Induced Voltage Impact Based on the Winding Connection by Diogo P. V. Galo, Thales A. C. Maia, Braz de J. Cardoso Filho

“…Doubly salient reluctance machines exhibit a simple structure, robust mechanical strength, excellent fault tolerance, and a wide range of speed regulation, which makes them suitable for in-wheel applications. …”
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Wind Field Characteristics of the 13 June 2014 Downburst Event in Beijing Based on Meteorological Tower Records by Shi Zhang, Yibo Wang, Zengzhi Qian, Kexin Guo, Xiaoda Xu, Daxing Zhou, Qing Cao

“…Understanding the characteristics of downburst wind fields is crucial for studying structural resistance to downbursts. Based on measured data from the 325 m meteorological tower in Beijing, this paper investigates the spatiotemporal evolution of mean and fluctuating winds during a non-stationary downburst. …”
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The Adoption of Technology Acceptance Model in E-commerce with Artificial Intelligence as a Mediator by Aram Massoudi, Muslim N. Zaidan, Azwar Qasim Agha

“…A survey was conducted with 352 Iraqi participants who participate in online shopping. Structural equation modelling was applied for data analysis. …”
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Heteronuclear Fe-Mn Cyclopentadienyl Complexes Supported on Boehmite. Thermochemistry and Thermodynamics of their Decomposition by A.I. Rustamova, R.M. Muradxanov, S.N. Osmanova, F.K. Pashayeva, A.N. Mammadov, D.B. Tagiyev, E.H. Ismailov

“…However, the electron paramagnetic resonance (EPR) spectra of these samples clearly show intense signals characteristic of superpara/ferromagnetic particles of iron and manganese oxides, as well as EPR signals from isolated Fe3+ substituting Al3+ ions in the aluminum oxide structure. EPR spectra most of the iron and manganese is stabilized on the surface of poorly crystallized aluminum oxide in the form of nanostructured iron and manganese oxides. …”
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Determinants of ICT Adoption and Performance in Healthcare: The Role of Individual Attributes and Organizational Contextual Factors by Abey Jose, Alejandro F. Mac Cawley, Luis Enberg Gaete, Guilherme Luz Tortorella, Roberto Vassolo, Manisha Kumar, Nick Rich, Maneesh Kumar

“…Data was analyzed using Partial Least Squares Structural Equation Modelling (PLS-SEM) and multiple regression for micro-level constructs. …”
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Analysis of the Spatial and Temporal Differences of China’s Power Carbon Footprint by Zhen-Yu Zhao, Shu-Guang Yuan, Yu Fu, Ying Wang, Heng Li

“…Moreover, through the statistics of China’s power production, this paper calculates the depth of China’s PCF and analyzes the temporal and spatial differences of China’s PCF depth from the three aspects of regional power installation structure, power deficit, and PCF transfer. The results obtained illustrate, firstly, that China’s overall PCF continues to increase, with the depth of PCF moving eastward. …”
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Complex Modeling of the Effects of Blasting on the Stability of Surrounding Rocks and Embankment in Water-Conveyance Tunnels by Xian-qi Zhou, Jin Yu, Jin-bi Ye, Shi-yu Liu, Ren-guo Liao, Xiu-wen Li

“…Calculation results demonstrated that displacement generally attenuated from the tunnel wall to the internal structure of rocks under the effect of blasting seismic waves. …”
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Antiviral and Immunoenhancing Properties of 7-Thia-8-Oxoguanosine and Related Guanosine Analogues by Donald F Smee, Howard B Cottam, Brahma S Sharma, Ganesh D Kini, Ganapathi R Revankar, Emmanuel A Ojo-Amaize, Robert W Sidwell, Weldon B Jolley, Roland K Robins

“…7-thia-8-oxoguanosine (TOGuo) is the first reported structure of a family of modified guanosine analogues exhibiting antiviral activity in rodent models. …”
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A dendritic hexamer acceptor enables 19.4% efficiency with exceptional stability in organic solar cells by Tao Jia, Tao Lin, Yang Yang, Lunbi Wu, Huimin Cai, Zesheng Zhang, Kangfeng Lin, Yulong Hai, Yongmin Luo, Ruijie Ma, Yao Li, Top Archie Dela Peña, Sha Liu, Jie Zhang, Chunchen Liu, Junwu Chen, Jiaying Wu, Shengjian Liu, Fei Huang

“…Recently emerging giant molecular acceptor (GMA) materials offer various advantages, such as precise chemical structure, high molecular weight (beneficial to film stability under several external stress), and impressive device efficiency, making them a promising candidate. …”
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Efficacy of a complex plant-based preparation for poultry mycotoxicosis by E. V. Kuzminova, E. P. Dolgov, M. P. Semenenko, P. V. Miroshnichenko

“…Antitoxin therapy had a positive effect on liver structure and functions and that fact was confirmed by a decrease in aminotransferase level in serum and normal levels of total protein. …”
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Natural selection and adaptive traits in the Maniq, a nomadic hunter-gatherer society from Mainland Southeast Asia by Tobias Herzog, Maximilian Larena, Wibhu Kutanan, Helmut Lukas, Martin Fieder, Helmut Schaschl

“…Genes under positive selection were enriched in pathways related to immunity, metabolic regulation, structural adaptation, cardiovascular performance, and neuromodulatory traits. …”
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