Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing by Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang

“…There were significant differences in microbial community structure between different severity groups, and microbial abundance was negatively correlated with disease severity. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Late-time Optical and X-Ray Emission Evolution of the Oxygen-rich SN 1996cr by Daniel Patnaude, Kathryn E. Weil, Robert A. Fesen, Dan Milisavljevic, Ralph P. Kraft

“…Thus, continued monitoring of bright and nearby SNe provides valuable clues about both the progenitor structure and its pre-SN evolution. Here we present late-time, multiepoch optical and Chandra X-ray spectra of the core-collapse SN, SN 1996cr. …”
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Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

“…Alpinia officinarum, commonly known as Galangal, is not only widely used as a medicinal plant but also holds significant ornamental value in horticulture and landscape design due to its unique plant structure and floral aesthetics in China. This study evaluates the impact of current and future climate change scenarios (ssp126, ssp245, ssp370, and ssp585) on the suitable habitats for A. officinarum in China. …”
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A randomized controlled study on the effectiveness of a diabetes self-management app in Bangladesh by Bilkis Banu, Nasrin Akter, Sujana Haque Chowdhury, Nusrat Hossain Sheba, Md. Abdul Hakim Majumder

“…Data were collected using a semi-structured questionnaire through face-to-face interview. …”
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Assessing the Dark Matter Content of Two Quasar Host Galaxies at z ∼ 6 through Gas Kinematics by Qinyue Fei, John D. Silverman, Seiji Fujimoto, Ran Wang, Luis C. Ho, Manuela Bischetti, Stefano Carniani, Michele Ginolfi, Gareth Jones, Roberto Maiolino, Wiphu Rujopakarn, N. M. Förster Schreiber, Juan M. Espejo Salcedo, L. L. Lee

“…By combining deep observations at both low and high resolution, we recover the diffuse emission, resolve its structure, and measure the rotation curves from the inner region of the galaxy to its outskirts using DysmalPy and ^3D Barolo . …”
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Lattice-based interpenetrating phase composite metamaterial fabricated with hybrid material extrusion process for tunable mechanical properties by Ritik Raj, Jung-Ting Tsai, Mayur Jiyalal Prajapati, Jeng-Ywan Jeng

“…Overall, this study presents an innovative fabrication technique for IPC metamaterials, revealing how the strategic placement and stacking sequence of secondary materials within the primary structure significantly influences their mechanical properties.…”
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Changes in the intestinal microbiota induced by the postnatal environment and their association with hypertension by Patrizia Dardi, Camille Perella Coutinho, Sarah de Oliveira, Simone Aparecida Teixeira, Renaide Rodrigues Ferreira Gacek, Eduardo Purgatto, Marco Aurélio Ramirez Vinolo, Marcelo Nicolás Muscará, Luciana Venturini Rossoni

“…In this sense, the current study explored the influence of normotensive and hypertensive postnatal environments on the intestinal microbiota structure, composition, and functional capacity of SHR and Wistar rats. …”
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Roles of core nosZ denitrifiers in enhancing denitrification activity under long-term rice straw retention by Shijie Zhang, Shijie Zhang, Mengyao Hou, Mengyao Hou, Bing Li, Bing Li, Panfeng Guan, Panfeng Guan, Qing Chi, Qing Chi, Hao Sun, Hao Sun, Hangbo Xu, Hangbo Xu, Dongjie Cui, Dongjie Cui, Yupan Zhu, Yupan Zhu

“…Correspondingly, treatments with rice straw retention resulted in the development of a similar community composition (P < 0.05), structure (P = 0.001), and more positively interconnected network, as well as similar specific keystone taxa of nosZ denitrifiers, relative to those in non-rice straw mode. …”
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RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study by Andrea Miranda-Mendizabal, Diana Vetter, Juan Zambrano, Jeff Zarp, Victor Chavarría, Anna Giménez-Palomo, Meritxell Gonzalez-Campos, Marc Valenti, Lara Walczer Baldinazzo, Sara Siddi, Maurizio Ferrari, Dinah Weissmann, Chantal Henry, Josep Maria Haro, Lars Vedel Kessing, Eduard Vieta

“…Methods and analysis Multicentre cross-sectional study including an adult sample of inpatients or outpatients diagnosed with BD or MDD, currently treated for a major depressive episode. A structured diagnostic interview based on validated scales will be conducted. …”
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Digital Literacy on SME Business Performance and The Mediating Role of Entrepreneurial Skills by Intan Novela Q.A, Hunik Sri Runing Sawitri, Asri Laksmi Riani, Suryandari Istiqomah, Anastasia Riani Suprapti, Mugi Harsono

“…Data were collected through online surveys and offline methods. Structural Equation Modeling with Partial Least Squares (SEM-PLS) was used to test the hypotheses. …”
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The hypoxia adaptation strategy of the big-belly seahorses (Hippocampus abdominalis) with tuft gills by Long-Wu Jia, Le-Le Zhang, Hong-Wei Yang, Chun-Yu Hou, Lin Shi, Yu-Ping Hou, Guo-Dong Zheng, Xiao-Lei Su, Kai Wang

“…In this study, we compared the gill structures of the big-belly seahorses (Hippocampus abdominalis, BBS) with lamellae gill fish and evaluated the effects of hypoxia on BBS. …”
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Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed Tortoise (Indotestudo elongata... by Bochaton, Corentin, Chantasri, Sirikanya, Maneechote, Melada, Claude, Julien, Griggo, Christophe, Naksri, Wilailuck, Forestier, Hubert, Sophady, Heng, Auertrakulvit, Prasit, Bowonsachoti, Jutinach, Zeitoun, Valéry

“…This allowed us to study the size structure of the archaeological populations at different sites and to reveal the human exploitation strategies of these animals. …”
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Altitudinal patterns of bacterial communities across soil layers in the alpine meadows of the Qinghai-Tibet Plateau by Zhiyuan Chen, Yeteng Xu, Xinyue Wang, Tong Ma, Yang Liu, Xiang Qin, Wei Zhang, Tuo Chen, Guangxiu Liu, Binglin Zhang

“…Microorganisms in the soils of alpine meadows on the Qinghai-Tibet Plateau are pivotal in sustaining ecosystem functionality and stability. The community structure and functional composition of these microbes exhibit pronounced altitudinal variations; however, specific distribution patterns across different soil layers remain inadequately elucidated within alpine meadow ecosystems. …”
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Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis by Kaiwen Sheng, Jun Chen, Ruitang Xu, Haoqiang Sun, Ran Liu, Yongjie Wang, Wenwen Xu, Jiao Guo, Miao Zhang, Shuai Liu, Juan Lei, Yawen Sun, Yang Jia, Dianhao Guo

“…Results Our study identified enhancer-specific activation within epithelial cells orchestrated by the three-dimensional structure of chromatin that regulates SERPINH1 transcription, and promotes the epithelial-mesenchymal transition (EMT) and metastasis of ESCC. …”
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Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Our Galaxy [version 2; peer review: 2 approved] by Pamela Klaassen, Maria Beltrán, Alessio Traficante, Mark Booth, Kate Pattle, Jonathan Marshall, Joshua Lovell, Brandt Gaches, Alvaro Hacar, Nicolas Peretto, Caroline Bot, Doris Arzoumanian, Thomas Stanke, Gaspard Duchêne, Ana Duarte Cabral, Antonio Hales, David Eden, Patricia Luppe, Jens Kauffmann, Elena Redaelli, Sebastian Marino, Álvaro Sánchez-Monge, Andrew Rigby, Dmitry Semenov, Eugenio Schisano, Mark Thompson, Silvia Spezzano, Claudia Cicone, Friedrich Wyrowski, Martin Cordiner, Tony Mroczkowski, Doug Johnstone, Luca Di Mascolo, Minju Lee, Eelco van Kampen, Thomas Maccarone, Daizhong Liu, Matthew Smith, Amélie Saintonge, Sven Wedemeyer, Alexander Thelen

“…Here we present a plan for observing the Galactic Plane and circumstellar environments to quantify the physical structure, the magnetic fields, the dynamics, chemistry, star formation, and planetary system evolution of the galaxy in which we live with AtLAST; a concept for a new, 50m single-dish sub-mm telescope with a large field of view which is the only type of facility that will allow us to observe our Galaxy deeply and widely enough to make a leap forward in our understanding of our local ecology.…”
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High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding by Michell, Craig, Collins, Joanna, Laine, Pia K., Fekete, Zsófia, Tapanainen, Riikka, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.

“…The genome was assembled using 25X PacBio HiFi sequencing data and scaffolded utilizing a Hi-C chromosome structure capture approach. After manual curation, the assembled genome length was 2,930,972,003 bp with N50 scaffold of 125.8 Mb. 93.16% of the assembly could be assigned to 25 identified chromosomes (23 autosomes plus X and Y), matching the published karyotype. …”
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Effects of Artemisia argyi leaf water extract (AWE) on growth performance, muscle quality, intestinal microbial, and metabolomics of common carp (Cyprinus carpio) by Di Sun, Nanyang Zeng, Yingjia Pan, Qingsong Shu, Jixing Zou, Yingshi Huang, Guoxia Wang, Jun Shi

“…The effects of AWE supplementation were assessed through various parameters including growth performance, flesh quality, biochemical indices, tissue structure, intestinal microbiota composition, and metabolomics analysis. …”
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DeepGolf: A fine-grained perception framework for golf course distribution in the real world based on multi-source remote sensing data by Ning Li, Yingchao Feng, Wenhui Diao, Xian Sun, Liang Cheng, Kun Fu

“…This paper presents DeepGolf, an advanced framework that integrates geographic information with deep neural features to accurately extract golf course distributions in real-world scenarios. DeepGolf is structured into three main modules: geographic query, detection, and fine extraction. …”
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Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons by Jones, Auriane G., Schaal, Gauthier, Boyé, Aurélien, Creemers, Marie, Derolez, Valérie, Desroy, Nicolas, Fiandrino, Annie, Mouton, Théophile L., Simier, Monique, Smith, Niamh, Ouisse, Vincent

“…Here, we analyze a dataset composed of macrobenthic invertebrate abundances and environmental variables (hydro-morphology, water, sediment and macrophytes) gathered across 29 Mediterranean coastal lagoons located in France, to characterize the main drivers of community composition and structure. Using correlograms, linear models and variance partitioning, we found that lagoon hydro-morphology (connection to the sea and lagoon surface), which affects the level of environmental variability (salinity and temperature), as well as lagoon-scale benthic habitat diversity (using macrophyte morphotypes) seemed to regulate macrofauna distribution, while eutrophication and associated stressors like low dissolved oxygen, acted upon the existing communities, mainly by reducing species richness and diversity. …”
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