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4801
Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein
Published 2025-03-01“…We applied these methods to evaluate condensation of the SARS-CoV-2 nucleocapsid (N) protein under GSK3 inhibitor treatment, which we had previously identified in our HCS campaign to induce condensation with well-defined structure-activity relationships (SAR). Using htSMT, we observed robust changes in N protein diffusion as early as 3 h post GSK3 inhibition. …”
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4802
Editorial
Published 2019-07-01“…Despite these heavy criticisms of established politicians and (party) structures, the authors also summarise some more hopeful suggestions by respondents centring around the role of party youth organisations. …”
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4803
Topographie et restitution du chantier de l’aqueduc d’Arles (Bouches-du-Rhône)
Published 2023-12-01“…It was greatest upstream of the crossing structure, then gradually diminished to prevent overflow caused by excessively rapid slowing. …”
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4804
The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures
Published 2016-02-01“…The empirical evidence on whether newer drugs can decrease overall healthcare expenditures may enable private and public health policymakers to develop new drug benefit structures. **Objective:** This paper investigates the impact of new drugs and drug classes on overall healthcare expenditures. …”
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4805
Recessive transition of rural residential land use from the perspective of value co-creation: A case study of Yiwu City, Zhejiang
Published 2025-01-01“…[Results] (1) Value co-creation of ural residential land follows the process model of “value consensus-value execution-value win-win” and the operational paradigm of “subject interaction - capacity embedding - benefit sharing”, driving the “element integration - structure reorganization - function optimization” of rural residential land use system, resulting in the dynamic evolution of diverse values such as residential security, economic property, production and operation, ecological protection, and cultural inheritance, and achieving the recessive rural residential land use transition. (2) Yiwu’s practice path of guiding multiple stakeholders to interact collaboratively, constructing “value consensus” for rural residential land, driving with multiple forces, and implementing “value execution” for rural residential land through multi-dimensional rule interaction is a successful model for realizing the recessive rural residential land use transformation through value co-creation. (3) Through the practice of value co-creation, Yiwu has achieved a transformation of the functional value of rural residential land from residential security orientation to economic property orientation, and then to a comprehensive and coordinated approach that encompasses residential security, production and operation, economic assets, and ecological protection, etc. …”
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4806
Experiences of working as a clinical nurse while pregnant during the coronavirus disease-2019 pandemic: a qualitative study
Published 2025-02-01“…Purposive sampling, combined with maximum variation strategy and snowball sampling, were utilized to identify and select participants from tertiary-teaching hospitals, specialized hospitals, and community hospitals in Zhejiang Province, southeastern China. Online semi-structured individual interviews were used to collect data, and conventional content analysis was used to analyze the data. …”
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4807
Cobalt titanate nanocatalyst for enhanced photodegradation of atrazine: kinetics, degradation efficiency, and mechanistic analysis
Published 2025-02-01“…Raman spectroscopic analysis showed vibrations typical for Ti–O and Co–O bonds and confirmed a well-defined cobalt titanate structure. Thermogravimetric analysis (TGA) showed that the nanoparticles remained stable up to 800 °C. …”
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4808
The role of Pharmaceutical Marketing in Prescribing Decisions in a Developing Country: A Comprehensive Study Exploiting Theory of Planned Behaviour
Published 2024-11-01“…Population was physicians in outpatient clinics in both private and governmental hospitals in Sana’a, capital city of Yemen. A structured questionnaire was designed to measure the influence of drug-promoting marketing techniques on physicians’ prescribing decisions. …”
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4809
An automated adaptive trading system for enhanced performance of emerging market portfolios
Published 2025-02-01“…At the same time, significant structural changes in the industry have occurred, with passive investing gaining momentum. …”
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4810
Computer simulation of the soil water regime under an apple orchard in a mountainous area (using the example of the leached chernozem of the experimental agricultural station Gorno...
Published 2025-01-01“…It has been established that the upper well-structured horizons of leached chernozem under an apple orchard have a greater water-holding capacity; their water-retention curves are more flattened. …”
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4811
The potential therapeutic effects of coenzyme Q10 on the sciatic nerve regeneration following short- and long-term injury
Published 2025-01-01“…Microscopic examinations indicated that LTI produced a significant change in the nerve structure than STI. CoQ10 ameliorated the degree of injury. …”
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4812
Oral health status, behavior and impact profile among naval personnel in the Malaysian naval armed forces
Published 2025-02-01“…Additionally, the oral health behaviours and oral health impact profiles of the participants were assessed through a structured questionnaire. Results A total of 176 naval personnel participated in the study. …”
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4813
Land use transition and its driving mechanisms in China’s human-elephant conflict areas
Published 2025-01-01“…In the core conflict areas, a multi-crop structure dominated by rubber has formed (accounting for 69.8% of the planting area). (2) Land use in the core conflict zone exhibits relatively extensive patterns, with land transfer rates and input-output efficiency demonstrating significantly lower values compared to those observed in peripheral regions. (3) Land use transition is influenced by multiple factors, including Asian elephant activities, economic development, and agricultural policy adjustments. …”
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4814
Role of Serum and Ultrasonometric Markers in the Early Diagnosis of Malignant Transformation of Periductal Liver Fibrosis in Patients with <i>Opisthorchis Felineus</i> Infection
Published 2024-01-01“…During the analytical stage, the relationship between the structural features of the liver ac- cording to the results of ultrasound examination (presence of opisthorchiasis-associated periductal fibrosis), clinical parameters, parasitological study data (infection intensity), and changes in biochemical, immunological parameters and tumor markers in patients against the background of O. felineus infection was assessed. …”
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4815
Visualization of Small Vessels by Micro–Computed Tomography Using Titanium Dioxide Nanoparticles as a Novel Contrast Agent
Published 2025-01-01“…No perfusion-induced damage or abnormal structures were observed. The signals of the contrast agents were detected clearly, and the tissue histology was of adequate quality for pathological diagnosis. …”
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4816
Medical students and ChatGPT: analyzing attitudes, practices, and academic perceptions
Published 2025-02-01“…Methods An anonymous, structured questionnaire was developed using Google Forms and administered to medical students as part of a cross-sectional study. …”
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4817
Des vestiges liés à la phase de construction de l’aqueduc de la Brévenne à Limonest (Métropole de Lyon) ?
Published 2023-12-01“…In the current state of our excavations and knowledge, we suggest that they should be identified as standardised structures or storage areas or as drains for evacuating rainwater during the construction of the aqueduct in somewhat clayey soils.…”
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4818
Sciatic nerve analysis in thyroid hormone transporters Mct8 and Oatp1c1 knockout mice
Published 2025-02-01“…Conclusions: Altogether, our data point to a largely unaffected sciatic nerve structure and function in the absence of MCT8 and OATP1C1.…”
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4819
FERRAMENTAS DE MARKETING: ESTUDO DE CASO COM CONSUMIDORES DE SUPERMERCADOS DA CIDADE DE CARANGOLA – MG
Published 2019-09-01“…As research tools bibliographic research and survey using questionnaires were used. semi-structured. For data analysis we used the technique of content analysis. …”
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4820
Social participation challenges and facilitators among Chinese stroke survivors: a qualitative descriptive study
Published 2025-02-01“…Individual face-to-face semi-structured interviews were conducted with 30 first-time or recurrent stroke survivors recruited from a rehabilitation unit and a community health centre in China. …”
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