BuDDI: Bulk Deconvolution with Domain Invariance to predict cell-type-specific perturbations from bulk. by Natalie R Davidson, Fan Zhang, Casey S Greene

“…BuDDI achieves this by learning independent latent spaces within a single variational autoencoder (VAE) encompassing at least four sources of variability: 1) cell type proportion, 2) perturbation effect, 3) structured experimental variability, and 4) remaining variability. …”
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InceptionDTA: Predicting drug-target binding affinity with biological context features and inception networks by Mahmood Kalemati, Mojtaba Zamani Emani, Somayyeh Koohi

“…Transformers struggle with scalability, while graph-based methods have difficulty handling large datasets and complex molecular structures. In this paper, we introduce InceptionDTA, a novel drug-target binding affinity prediction model that leverages CharVec, an enhanced variant of Prot2Vec, to incorporate both biological context and categorical features into protein sequence encoding. …”
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Application of 2D and 3D Electrical Resistivity Tomography (ERT) in Predicting Soil Erodibility in Oredide Village, Auchi in Etsako West LGA of Edo State, Southern Nigeria by D.A. Babaiwa, M.O. Ikponmwen

“…The inverted 2-D resistivity structure shows high resistivity distribution near-surface >1000 Ωm, which are indications of vulnerabilities to erosion in the study area with depth of scouring being 15 m. 3D horizontal depth slice show four layers with depths: 0 – 3.5 m, 3.5– 7.52 m, 7.52 – 12.2 m and 12.2 – 17.5 m having corresponding resistivity values that vary from 465 – 285939 Ωm across each layer respectively. …”
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Smokeless, not harmless: Understanding Naswar's cardiovascular risks in the northwestern Pakistan by Ihsanur Rahman, Fayaz Ahmad, Naveed Sadiq

“…Consecutive sampling facilitated data collection through interviews using pre-structured questionnaire. Multivariable logistic regression analyses computed adjusted odds ratios for Naswar-CAD association. …”
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Association of functional variants in miRNA genes with the risk of coronary heart disease by Taqweem Ul Haq, Muhammad Riaz Khan, Sajjad Ali, Tariq Aziz, Thamer H. Albekairi, Aftab Ali Shah

“…In MIR4242, a novel triplet insertion (CAC) was identified exclusively in CHD samples, predicated to disrupt the stem-loop structure ofmiR-4274. However, MIR3117 showed no association with CHD, as confirmed by Sanger sequencing of 40 samples. …”
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Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later by Tore K Kvien, Hilde Berner Hammer, Ida K Haugen, Barbara Slatkowsky-Christensen, Alexander Mathiessen

“…Background Structural pathology may be present in joints without radiographic evidence of osteoarthritis (OA). …”
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A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms by Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine

“…The efficacy of RCI may differ from that of synthetic ACTH treatments based on the structure of peptide; however, no head-to-head clinical trials have compared the efficacy of RCI and synthetic ACTH treatments. …”
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Computational and In silico study of novel fungicides against combating root rot, gray mold, fusarium wilt, and cereal rust. by Mollah Naimuzzaman, Md Mahabub Hasan, Ajoy Kumer, Abu Yousuf Hossin, Mohammad Harun-Ur-Rashid, Swapan Kumar Roy, Abu Noman Faruq Ahmmed, Jamal Uddin

“…However, MD was performed to check the validation and calculation the docking procedure and stability of the protein ligand docked complex accounting of RMSD, RMSF, SASA, Radius of gyration (Rg), Protein secondary structure elements (SSE), Ramachandran plot which confirm that the stability of docked complex is so high, and number of calculating the hydrogen bonds is more than good enough, as a result it is concluded the docking procedure is valid. …”
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Risk factors associated with high altitude sickness among travelers: A case control study in Himalaya district of Nepal. by Sishir Poudel, Laxman Wagle, Mukhiya Ghale, Tara Prasad Aryal, Sushan Pokharel, Binay Adhikari

“…Data were collected between September and November, 2023 via predesigned structured questionnaire by trained medical officers in, and analyzed using SPSS version 25. …”
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Complete chloroplast genomes of 13 species of the Impatiens genus for genomic features and phylogenetic relationships studies by Qinqin Yong, Meijun Li, Zhi Li, Chao Luo, Jinling Zhang, Xinxiang Bai

“…The results revealed that these chloroplast genomes all had double-stranded tetrad structures ranging in length from 151,284 bp to 152,421 bp, including a total of 113 genes, including 80 protein-coding genes, 29 transfer RNAs, and 4 ribosomal RNAs. …”
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Clinical outcomes of circumcisions and prevalence of complications of male circumcisions: A five-year retrospective analysis at a teaching hospital in Ghana. by Sylvester Appiah Boakye, Frank Obeng

“…A five-year retrospective descriptive and analytic study was conducted at Ho Teaching Hospital, using a structured data extraction sheet to collect demographic, clinical, and circumcision-related data from 186 cases. …”
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Integrated high-precision real scene 3D modeling of karst cave landscape based on laser scanning and photogrammetry by Congyuan Zhang, Jianping Chen, Ping Li, Sipeng Han, Jie Xu

“…By combining ground-based and aerial remote sensing techniques, and based on 3D laser scanning and photogrammetry, we have successfully constructed a real scene 3D model of the internal structure of a karst cave with a precision better than 4 cm. …”
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Individual differences in developmental trajectory leave a male polyphenic signature in bulb mite populations by Deere, Jacques A., Smallegange, Isabel M.

“…When alternative phenotypes show different life history trajectories, developmental plasticity can also affect, and be affected by, population size-structure in an eco-evolutionary interaction. Developmental plasticity often functions to anticipate future conditions but it can also mitigate current stress conditions. …”
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The Serbian version of the Pandemic-Related Pregnancy Stress Scale (PREPS-SRB)-A validation study. by Konstantin Kostić, Aleksandra Kostić, Aleksandra Petrović, Andrija Vasilijević, Jelena Milin-Lazović

“…The CFA showed very good fit indices for the Serbian sample, confirming the factor structure of the original English version. The RMSEA value of 0.056 (0.036-0.075) and values for fit indices TLI (0.961) and CFI (0.974) were above the cut-off of ≥0.95, indicating an excellent fit. …”
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Patient experiences and discomfort associated with mid-palatal temporary skeletal anchorage devices by Aoife P. Barry, Vanessa Knode, Padhraig S. Fleming, Björn Ludwig

“…Abstract Background Mid-palatal placement of temporary skeletal anchorage devices (TSADs) has become increasingly popular among clinicians due to high success rates, low associated risk and streamlining and enhanced customization of associated supra-structures. There is however limited patient data in relation to associated experiences and impacts. …”
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Subjective Career Success in The Modern Career: A Parallel Mediation of Perceived Internal and External Employability by Syahrizal Syahrizal, Tika Rahma Yani Siregar

“…To test the hypotheses, a quantitative approach incorporating structural equation modelling (SEM) was employed using SmartPLS 4.0. …”
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Design and experiment of air-suction drum-type seedling seeder for irregular-shaped vegetable seeds by Yanjun Li, Yunqiang Liu, Yichao Ning, Hongxin Wu, Yaqian Zhao

“…Abstract In order to meet the requirements of hole tray seedling transplanting operation for tomato, pepper and other irregular-shaped vegetable seeds, and to solve the problems of poor seeding performance of irregular-shaped vegetable seeder, this study designed an Air-suction Drum-type Precision Seeder. The basic structure and working principle of the seeder were elaborated, the key components were designed, and the distribution of the airflow field in the flow paths of the suction nozzles of three different hole types was simulated and analyzed by Fluent software; the relationship between the main influencing factors of the seeder’s operational performance (suction air pressure, clearing air pressure, and vibration frequency of the seed cassette) and the sowing indexes (replanting rate, cavity rate, and qualification rate) was investigated and the relationship between the factors and the sowing indexes (reseeding rate, cavity rate, and qualification rate) was analyzed by the quadratic orthogonal combination experiment method. …”
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Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing fact... by Ilkay Celik Gulsoy, Terrens N V Saaki, Michaela Wenzel, Simon Syvertsson, Taku Morimoto, Tjalling K Siersma, Leendert W Hamoen

“…Bacterial cytokinesis begins with polymerization of the tubulin homologue FtsZ into a ring-like structure at midcell, the Z-ring, which recruits the late cell division proteins that synthesize the division septum. …”
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Saintes/Mediolanum, cité des Santons et Bordeaux/Burdigala, cité des Bituriges Vivisques : destins croisés by Louis Maurin, Alain Bouet, Eneko Hiriart, Guilhem Landreau, Christophe Sireix, Dominique Tardy

“…AD, above all in the establishing of an urban layout and the construction of structures for convenience and health (fountains, aqueducts); though none of this is that distinctive for Roman Gaul. …”
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On occupational safety in Ukraine in the context of social risks of preserving human capital by Olga Hrynkevych, Petro Ostroverkh, Vasyl Hrynkevych

“…The authors use desk research methods, statistical methods to analyze the dynamics and structure of indicators of official statistics, and administrative data on occupational diseases, injuries, and industrial accidents, considering the SDG monitoring program in Ukraine. …”
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