Mechanistic insights into gut microbe derived siderophores and PHD2 interactions with implications for HIF-1α stabilization by Jainabbi Irshad Ahmed Patel, Jagadeesha Poyya, Apeksha Padakannaya, Namrata Manjunath Kurdekar, Ajay Sathayanarayan Khandagale, Chandrashekhar Gajanan Joshi, Santosh R. Kanade, Kapaettu Satyamoorthy

“…This study also helps in understanding the structural mechanisms by which gut microbiota regulate HIF-1α via PHD2 inhibition through the secretion of siderophores. …”
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Gaining Insight into Operative Performance: Analysis of an Automated 360-Degree Feedback Tool Among Perioperative Staff by Stefanie J. Soelling, MD, MPH, Robert D. Sinyard, MD, Lauren Spigel, MPH, Max Riley, MD, Paul Gregory, PhD, Nick Perdomo, MS, Yves Sonnay, MScPH, Steven Yule, PhD, Steven J. Fishman, MD, Douglas S. Smink, MD, MPH, FACS

“…Aggregated survey responses were provided to surgeons and surgical leadership. We performed semi-structured interviews with 10 surgeons and 5 surgical leaders. …”
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Blast loading prediction in a typical urban environment based on Bayesian deep learning by Weiwen Peng, Meilin Pan, Chunjiang Leng, Shufei Wang, Wei Zhong

“…Explosion events in urban environment, such as terrorist attacks, accidental industrial explosions and missile attacks in war, can be destructive to residents and properties, causing great casualties and structural damages. Rapid and accurate methods for blast loading prediction in urban environment are crucial for risk mitigation and emergency response planning. …”
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HDAC Inhibition Modulates Cardiac PPARs and Fatty Acid Metabolism in Diabetic Cardiomyopathy by Ting-I Lee, Yu-Hsun Kao, Wen-Chin Tsai, Cheng-Chih Chung, Yao-Chang Chen, Yi-Jen Chen

“…Electrocardiography, echocardiography, and western blotting were used to evaluate the electrophysiological activity, cardiac structure, fatty acid metabolism, inflammation, and PPAR isoform expressions in the control and streptozotocin-nicotinamide-induced DM rats with or without MPT0E014. …”
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Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study by Ken Ohata, Kuangi Fu, Eiji Sakai, Kouichi Nonaka, Tomoaki Tashima, Yohei Minato, Akiko Ohno, Takafumi Ito, Yosuke Tsuji, Hideyuki Chiba, Makoto Yamawaki, Hideyuki Hemmi, Teruo Nakaya, Junichi Fukushima, Nobuyuki Matsuhashi

“…After circumferential mucosal incision for the target lesion, structured as the isolated pig esophagus 3 cm long, either C-ESD or OTF-ESD was randomly selected for submucosal dissection. …”
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PERCEPTION OF ONLINE VERSUS PHYSICAL LEARNING AMONGUNIVERSITY STUDENTS by Ramna Shafique, Muhammad Abdullah, Tooba Nasir, Sundas Salim, Sabrina Jam, Bina Fawad

“…The data was collected online via Google Forms. A structured, self-designed questionnaire was used to gather data. …”
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Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets by Yuanyuan Zhao, Jing Wang, Hao Wang, Yonggang Huang, Ming Qi, Simeng Liao, Peng Bin, Yulong Yin

“…In conclusion, GABA supplementation can enhance intestinal mucosal immunity by promoting jejunal SIgA secretion, which might be related with the T-cell-dependent pathway and altered gut microbiota structure and metabolism.…”
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Evaluation of Five Ready-to-Use Bases for the Topical Administration of Propranolol Hydrochloride to Treat Infantile Hemangioma by Chiara Lacassia, Annalisa Cutrignelli, Flavia Maria la Forgia, Sergio Fontana, Antonio Lopalco, Nunzio Denora, Angela Assunta Lopedota

“…<b>Results</b>: The results indicated that the release of the drug was significantly influenced by the internal structure and physicochemical properties of each base. …”
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Advancements in integrating MOFs into micro-arc oxidation coatings on Mg alloys: A perspective on PEO-MOF coatings as innovative corrosion inhibitors by A.G. Ramu, Daejeong Yang, Minjung Song, Dongjin Choi

“…Large specific surface areas, customizable topologies and functionalities, ordered pore structures, and many reactive sites make these materials famous. …”
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Late-onset first epileptic seizure and cerebral small vessel disease: role of juxtacortical white matter lesions by Adrian Nasca, Adrian Nasca, Leo Sokolovič, Leo Sokolovič, Oliver Koprda, Patrick Haage, Patrick Haage, Thorsten Schmidt, Juraj Kukolja, Juraj Kukolja

“…We aimed to further investigate the impact of white matter lesion (WML) burden and distribution pattern on LOFES.MethodsWe retrospectively compared structural MRI of LOFES patients (n = 39) aged 60 years or older to controls with a transient ischemic attack (TIA, n = 38) and to patient controls (n = 35). …”
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Determinants of Implementation of Evidence-Based Practice in Clinical Decision-Making among Nurses in Primary Health Care Facilities by Opeoluwa Oluwatoyin Olabode, Funmilayo A. Okanlawon, Emmanuel O. Adesuyi, Oluwadamilare Akingbade, Chinomso Nwozichi, Yetunde Olufunmilayo Tola

“…Data were collected through a structured questionnaire administered via the online survey platform Google Forms. …”
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Assessment of Knowledge, Attitude, and Associated Factors of Mpox Among Healthcare Professionals at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cros... by Teklehaimanot Kiros, Mulat Erkihun, Mitikie Wondmagegn, Andargachew Almaw, Ayenew Assefa, Ayenew Berhan, Dessie Tegegne, Alemie Fentie, Tegenaw Tiruneh, Birhanemaskal Malkamu, Mahider Shimelis, Eninur Dejen, Birhanu Getie, Shewaneh Damtie, Yenealem Solomon, Bekele Sharew

“…A pretested, and well‐structured, questionnaire was used to assess the sociodemographic characteristics, knowledge, and attitudes of HCPs. …”
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The formation mechanism of geological disasters on loess fill slopes revealed by the deformation characteristics of remolded loess under different stress paths by Shuran Meng, Shuran Meng, Dunyu Lv, Dunyu Lv, Ru Liu, Mancang Yu, Mancang Yu, Jianyu Zhang, Jianyu Zhang

“…When the lateral constraint is reduced to a critical state, the structure is completely unstable, and the deformation develops rapidly in a short time until it is destroyed. …”
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Deficiency of purinergic P2Y2 receptor impairs the recovery after renal ischemia-reperfusion injury and accelerates renal fibrosis and tubular senescence in mice by Kyuho Jeong, Jihyun Je, Theodomir Dusabimana, Jacques Karekezi, Tatang Aldi Nugroho, Edvard Ntambara Ndahigwa, Hyun Joon Kim, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park

“…KO mice showed severe kidney dysfunction and structural damage compared to WT mice. KO mice showed higher senescence-associated β-galactosidase expression and shorter telomere length than WT mice. …”
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Association of Self-DNA Mediated TLR9-Related Gene, DNA Methyltransferase, and Cytokeratin Protein Expression Alterations in HT29-Cells to DNA Fragment Length and Methylation Statu... by István Fűri, Ferenc Sipos, Sándor Spisák, Gergő Kiszner, Barnabás Wichmann, Andrea Schöller, Zsolt Tulassay, Györgyi Műzes, Béla Molnár

“…DNMT3A expression could also be induced by type-1 DNA treatment. DNA structure may play a significant role in activation of the TLR9-dependent and even independent proinflammatory pathways. …”
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Prospective cohort study of the evaluation of patient benefit from the redevelopment of a complete national forensic mental health service: the Dundrum Forensic Redevelopment Evalu... by Harry G Kennedy, Mary Davoren, Ken O’Reilly, Damian Mohan

“…The aim of Dundrum Forensic Redevelopment Evaluation Study (D-FOREST) is to complete a structured evaluation study of a complete national forensic mental health service, at the time of redevelopment of the National Forensic Mental Health Service for the Ireland.Methods and analysis D-FOREST is a multisite, prospective observational cohort study. …”
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The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice by Nikola Ferara, Vedran Balta, Domagoj Đikić, Dyana Odeh, Ana Mojsović-Ćuić, Lana Feher Turković, Dario Dilber, Anđelo Beletić, Irena Landeka Jurčević, Ivana Šola

“…The alterations in myocardial parameters were assessed by measuring metabolic, inflammatory, structural, and antioxidant markers. Our findings revealed that subchronic exposure to sinigrin in the myocardia of female mice resulted in a significant increase (<i>p</i> ≤ 0.05) in the levels of the myokine irisin, matrix metalloproteinases (MMP-2, MMP-9), catalase (CAT), and total glutathione (tGSH), alongside a marked decrease (<i>p</i> ≤ 0.05) in the levels of atrial natriuretic peptide (ANP), compared to the control group consisting of both female and male mice. …”
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Explaining the technological cooperation of knowledge and business ecosystems: an approach based on ecotone and ambidextrous organization theories by Bahman Norouzpour, Mahmoud Moradi, Mohamad Rahim Ramezanian, Mostafa Ebrahimpour Azbari

“…The systematic procedure of Strauss and Corbin was used to create a suitable structure for better understanding and classification of data and findings. …”
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Metabolite concentrations and the expression profiles of the corresponding metabolic pathway genes in eggplant (Solanum melongena L.) fruits of contrasting colors by M. A. Filyushin, E. A. Dzhos, A. V. Shchennikova, E. Z. Kochieva

“…Biochemical data corresponded to the differential expression pattern of the key genes encoding the structural proteins of metabolism and transport of the compounds analyzed.…”
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Development of Sr modified Al–Si–Mg–Fe based alloys for automotive components by H.R. Ammar, E. Samuel, A.M. Samuel, E. Elsharkawi, H.W. Doty, F.H. Samuel

“…The process of fragmentation/dissolution of the β-Al5FeSi phase during solution treatment at 540 °C is associated with the ductile Al matrix characterized by the formation of dimple structure. The lack of an age hardening response of the ternary Al–12%Si-0.045%Sr alloy results in low alloy strength, making this alloy unsuitable for automotive components that may be exposed to high temperatures. …”
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