Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…This review covers novel drug leads with antibacterial and cytotoxic activities isolated from deep-sea, desert, cryo, and volcanic environment Streptomyces from 2009 to 2019. The structure and chemical classes of the compounds, their relevant bioactivities, and the sources of organisms are presented.…”
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Unveiling the future: Wavelet- ARIMAX analysis of climate and diarrhea dynamics in Bangladesh’s Urban centers by Md. Waliullah, Md. Jamal Hossain, Md. Raqibul Hasan, Abdul Hannan, Mohammad Mafizur Rahman

“…The Wavelet-ARIMAX method, which uses wavelet analysis within the ARIMAX structure, is better at forecasting performance and model fit than the standard ARIMAX model. …”
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Contextualizing the challenges of education graduate students in the Philippines: translating needs analysis into strategic solutions by Nilo Jayoma Castulo, Arlyne C. Marasigan, Ma. Laarni D. Buenaventura, Jayson L. de Vera, Evelyn C. Bagaporo, Mark Ponce C. San Juan, Nathaniel S. Dalida

“…Respondents predominantly prefer enhancing their research skills through structured training, seminars, and workshops. The study provides a range of recommendations to improve graduate education and the need for further research in this area.…”
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Bioprospecting of a Native Plant Growth-Promoting Bacterium <i>Bacillus cereus</i> B6 for Enhancing Uranium Accumulation by Sudan Grass (<i>Sorghum sudanense</i> (Piper) Stapf) by Longyuan Wu, Lijuan Zhang, Ning Wang, Wei Huang, Yanzhi Wang, Meng Sun, Guofeng Zheng, Wei Wang, Chong Shi

“….), noted for its robust root structure and resilience to heavy metals, has garnered significant attention. …”
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AdS3 solutions in massive IIA with small N $$ \mathcal{N} $$ = (4, 0) supersymmetry by Yolanda Lozano, Niall T. Macpherson, Carlos Nunez, Anayeli Ramirez

“…Abstract We study AdS3 x S 2 solutions in massive IIA that preserve small N $$ \mathcal{N} $$ = (4, 0) supersymmetry in terms of an SU(2)-structure on the remaining internal space. We find two new classes of solutions that are warped products of the form AdS3 x S2 x M4 x ℝ. …”
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Optimum design of wind turbine foundation according to rebar detailing by Italo Linhares Salomão, Placido Rogério Pinheiro, Napoleão Vieira Nepomuceno, Gabriel Xavier Santiago Marinho, Matheus Martins Palmela Bastos de Oliveira, Joel J.P.C. Rodrigues, Bruno Ricardo de Almeida

“…This research proposes a Mixed Integer Linear Programming model to assist structural engineers in the reinforcement detailing phase of circular foundations, with a specific focus on wind tower foundations, aiming to optimise the design process and, consequently, reduce the costs associated with constructing these elements. …”
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ADAM-multi: software to simulate complex breeding programs for animals and plants with different ploidy levels and generalized genotypic effect models to account for multiple allel... by Thinh Tuan Chu, Thinh Tuan Chu, Just Jensen

“…We found that genomic models using dense bi-allelic markers could effectively predicted breeding values of individuals in a well-structure population despite the presence of multi-allelic QTL. …”
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Understanding Hydrogen Passivation Mechanism in poly-Si Passivating Contacts via SixNy Composition: Insights From Effusion Studies by Suchismita Mitra, Dirk Steyn, William Nemeth, Sumit Agarwal, Paul Stradins

“…Next, we investigate the mechanism of hydrogen passivation on symmetrical i-poly-Si/SiO2/i-poly-Si structures with different hydrogenating layers namely Si-rich SixNy , Al2O3 and a stack of Al2O3/SixNy, and conclude that a thin 15nm Al2O3 enables the best passivation. …”
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Limitation of the constitutional rights and freedoms of a person and a citizen in connection with the military aggression of the russian federation by Shevchuk L.

“…In the process of research, such methods of scientific knowledge as comparative, systemic and structural were observed. Results. In the course of this study, an analysis of the application of restrictions on the constitutional rights and freedoms of a person and a citizen in connection with the military aggression of the russian federation, as well as the effect of these restrictions on the ordinary life of an ordinary Ukrainian, their effectiveness in relation to the security of the state as a whole, was carried out. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…This article comprehensively reviews the structure and function of MAGEA4, as well as recent research progress in solid tumors, providing a theoretical foundation for the clinical translation of MAGEA4 and its application in immunotherapy.…”
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Estimating Geomagnetically Induced Currents in Southern Brazil Using 3‐D Earth Resistivity Model by Karen V. Espinosa, Antonio L. Padilha, Livia R. Alves, Adam Schultz, Anna Kelbert

“…Abstract Geomagnetically induced currents (GICs) result from the interaction of the time variation of ground magnetic field during a geomagnetic disturbance with the Earth's deep electrical resistivity structure. In this study, we simulate induced GICs in a hypothetical representation of a low‐latitude power transmission network located mainly over the large Paleozoic Paraná basin (PB) in southern Brazil. …”
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Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] by Jelena Ostojic, Safija Herenda, Semira Galijasevic, Borivoj Galic, Mladen Milos

“…The values of Arrhenius constants were found to be different; A = 4.635 s−1 was measured in the absence of inhibitor while in the presence of inhibitor Arrhenius constant was 1.745 s−1 showing that K2[B3O3F4OH] initiates conformational change in the structure of the HRP and subsequently reduces its activity.…”
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Feature selection enhances peptide binding predictions for TCR-specific interactions by Hamid Teimouri, Hamid Teimouri, Zahra S. Ghoreyshi, Zahra S. Ghoreyshi, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Jason T. George, Jason T. George, Jason T. George, Jason T. George

“…The results of our feature selection method are consistent with findings from hybrid approaches that utilize both sequence and structural data as input as well as experimental data.DiscussionOur theoretical approach highlights the role of feature selection in peptide-TCR interactions, providing a quantitative tool for uncovering the molecular mechanisms of the T-cell response and assisting in the design of more advanced targeted therapeutics.…”
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The problem of the oil-contaminated geo-environment and ways to solve it by K. L. Chertes, V. N. Pystin, O. V. Tupitsyna, I. M. Evgrafova

“…On the other hand, it is a potential basis for the construction of structures. Construction works are constantly carried out at the sites of oil producing and oil processing enterprises. …”
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Defining the Need for Causal Inference to Understand the Impact of Social Determinants of Health: A Primer on Behalf of the Consortium for the Holistic Assessment of Risk in Transp... by Nrupen A. Bhavsar, PhD, Rachel E. Patzer, PhD, David J. Taber, PharmD, Katie Ross-Driscoll, PhD, Rhiannon Deierhoi Reed, PhD, Juan C. Caicedo-Ramirez, MD, Elisa J. Gordon, PhD, MPH, Roland A. Matsouaka, PhD, Ursula Rogers, BS, Wendy Webster, MBA, Andrew Adams, MD, PhD, Allan D. Kirk, MD, Lisa M. McElroy, MD

“…This is partially due to the unstandardized and incomplete capture of the complex interactions between patients, their neighborhood environments, the tertiary care system, and structural factors that impact access and outcomes. …”
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Digital healthcare services in community pharmacies in Switzerland: Pharmacist and patient acceptability, and pharmacist readiness–the Pneumoscope™ pilot study by Claudine Backes, Coralie Godot, Cédric Yan Gujer, Noémie Obegi, Alexandre Perez, Alain Gervaix, Marie P. Schneider

“…Methods A 2-stage exploratory approach was conducted using mixed methods: 1) a qualitative analysis of pharmacists’ acceptability and readiness was developed using semi-structured interviews and focus groups ; 2) followed by a quantitative cross-sectional survey of patients’ acceptability of the device in CPs. …”
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Understanding the behavioral intention of rural women to engage in green poultry farming: A psychological analysis by Pouria Ataei, Hamed Ghadermarzi, Hamid Karimi, Meysam Menatizadeh, Nasim Izadi

“…A sample of 420 women was selected using a multi-stage clustering technique, and data were gathered through structured interviews. Statistical analysis was conducted with SPSS and PLS software to evaluate the relationships between HBM constructs and behavioral intention. …”
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Xanthomonas citri subsp. citri requires a polyketide cyclase to activate the type III secretion system for virulence by Shuying Zhu, Siyu Wu, Yanmin Liu, Zaibao Zhang, Huasong Zou

“…Here, we report the role of a polyketide cyclase (PKC) on the virulence in X. citri subsp. citri. Methods The structure of PKC was precisely predicted using Alphafold3. …”
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From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Bi... by Cíntia Marques, Alexandre Porcello, Marco Cerrano, Farid Hadjab, Michèle Chemali, Kelly Lourenço, Basste Hadjab, Wassim Raffoul, Lee Ann Applegate, Alexis E. Laurent

“…To specifically address this PDRN/PN ambiguity, this narrative review proposes a standardized structure-based nomenclature for these DNA-derived polymers, the “Marques Polynucleotide Cutoff”, set at 1500 kDa. …”
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A novel method for alumina preparation by electrotransformation AlCl3 solution under NH4Cl-catalyzed and CO2-injected conditions by Han X.-X., Liu Y.-M., Yang L.-X., Lu Y.-F., Wang R.-T., Zhang T.-A.

“…The results showed that, when the solution in the cathodic chamber was NH4Cl with CO2 injection, with electrotransformation time extension, pH increased slowly and the morphology of electrotransformation products were all rough and fluffy block structures. Increasing initial NH4Cl concentration effectively improved the product crystallization states, roasting products D(50) and D(90), and Al recovery rate.…”
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