Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4 by Asma Khatoon Zaidi, Anurag Kumar, Rohit Kumar, Jyoti Singh, Sneha Yadav, Archana Bharti Sonkar, Dharmendra Kumar, Neeraj Kumar Shrivastava, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas

“…We screened 2,11,192 potential leads through ZINC database, which were atleast 50 % structurally similar with SYR. After in-depth analysis, 900 molecules were shortlisted based on Lipinski's rule, optimal molecular weight, binding energy, hydrogen bonding, and ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties that render them viable MCT-4 inhibitors. …”
Get full text

Geoelectric Field Estimations During Geomagnetic Storm in North China From SinoProbe Magnetotelluric Impedances by Qihe Shao, Ying Liu, Yinhe Luo, Graham Heinson, Yixian Xu, Jinsong Du, Chao Chen

“…The measured impedances from 119 SinoProbe MT sites were convolved with geomagnetic observatory data to account for the Earth's complex three‐dimensional electrical resistivity structure. The resultant geoelectric field was then used to model the induced voltage distribution across the regional power transmission network in North China. …”
Get full text

Two for the Road: Measuring Regional Disparity and Agglomeration in Human Development Level and Transportation Infrastructure by Zhiheng Wang, Tao Xing, Daikun Wang, Hongkui Fan, Dongchuan Wang, Yanwang Wu, Qiaozhen Guo, Lina Xiu

“…The pattern of human development level in Qinghai-Tibet Plateau presents a “core-periphery” spatial structure with the transportation network as the axis. (2) On the whole, with the improvement of location conditions influenced by transportation infrastructure, the spatial aggregation of human development level is constantly improving, and the spatial disparity continues to decrease. (3) Locally, four spatial interaction patterns of high/low clustering are recognized and analyzed. …”
Get full text

MCU expression in hippocampal CA2 neurons modulates dendritic mitochondrial morphology and synaptic plasticity by Katy E. Pannoni, Quentin S. Fischer, Renesa Tarannum, Mikel L. Cawley, Mayd M. Alsalman, Nicole Acosta, Chisom Ezigbo, Daniela V. Gil, Logan A. Campbell, Shannon Farris

“…Fragmented mitochondria might have functional changes, such as altered ATP production, that could explain the structural and functional deficits at cKO synapses. …”
Get full text

EXPANDING PREVENTION THROUGH DESIGN (PtD) IN PRACTICE: INNOVATION, CHANGE, AND A PATH FORWARD by John Gambatese, Alistair Gibb, Phil Bust, Michael Behm

“…The researchers conducted fourteen structured focus group interviews of six different professional communities in the United Kingdom (UK), where PtD is integrated in practice through regulation. …”
Get full text

Association of burnout and working environment conditions in respiratory care professionals in Saudi Arabia: a cross-sectional study by Saad Al-Anazi, Saad Al-Anazi, Syed Shahid Habib, Thamir Al-khlaiwi, Abdulaziz Alhomaidi Alodhayani, Abdulmueen Alotaibi, Abdulmueen Alotaibi, Saja Aldulejan, Sufana Al Safadi, Fahad Saad Alshammari, Aqeelah Marar, Afaf Alrashdi, Alhanouf G. Almutairi, Mohammed Alshahrani

“…This study examines factors associated with burnout and working environment among respiratory therapists in Saudi Arabia.MethodsA structured questionnaire was used to collect data from respiratory therapists. …”
Get full text

The impact of individual and organizational factors on employee innovative work behavior: Empirical evidence from private companies in Vietnam by Tran Hai Yen, Chu Tien Minh, Nguyen Ngoc Diep, Khuc Dai Long

“…To test the hypotheses quantitatively, the study uses a two-stage second-order partial least squares structural equation modeling (PLS-SEM) method and a questionnaire-based study with 706 employees from private businesses in Vietnam. …”
Get full text

Physical, Spatial, and Molecular Aspects of Extracellular Matrix of In Vivo Niches and Artificial Scaffolds Relevant to Stem Cells Research by Maria Akhmanova, Egor Osidak, Sergey Domogatsky, Sergey Rodin, Anna Domogatskaya

“…Biochemical characteristics of natural extracellular matrix molecules regard diversity and structural complexity of matrix molecules, affinity and specificity of epitope interaction with cell receptors, role of non-affinity domains, complexity of supramolecular organization, and co-signaling by growth factors or matrix epitopes. …”
Get full text

Development of a Novel, Sensitive, Selective, and Fast Methodology to Determine Malondialdehyde in Leaves of Melon Plants by Ultra-High-Performance Liquid Chromatography-Tandem Mas... by Melisa E. Yonny, Ariel Rodríguez Torressi, Mónica A. Nazareno, Soledad Cerutti

“…Early production of melon plant (Cucumis melo) is carried out using tunnels structures, where extreme temperatures lead to high reactive oxygen species production and, hence, oxidative stress. …”
Get full text

Examining Competitive Strategies in Growing Coffee Industry with Game Theory by Hüseyin Daştan, Gürkan Çalmaşur, Meryem Aysin, Fatmanur Oral

“…It has become extremely important for the local economy that local businesses can compete and survive with these more institutionalized structures that also have brand advantages in competition. …”
Get full text

Material Characterization of High Dielectric Constant Polymer–Ceramic Composite for Embedded Capacitor to RF Application by Yang Rao, Jireh Yue, C. P. Wong

“…Polymer–ceramic composites have been of great interest as embedded capacitor material because they combine the processability of polymers with the desired electrical properties of ceramics. A novel nano-structure polymer–ceramic composite with very high dielectric constant (εr∼150 , a new record for the highest reported εr value of nano-composite) has been developed in our previous work. …”
Get full text

Experience of Filipinos with Spinal Cord Injury in the Use of Assistive Technology: An Occupational Justice Perspective by Daryl Patrick G. Yao, Kaoru Inoue, Michael P. Sy, Peter Bontje, Natsuka Suyama, Chiyomi Yatsu, Dante A. Perez, Yuko Ito

“…Filipinos with SCI deal with numerous structural and contextual factors in daily life. There has been partial enablement of OJ as they incorporate AT in their daily lives as occupational rights are far from being recognised and respected. …”
Get full text

Usability Evaluation of a Digital Teleradiology Case Study Using the System Usability Scale in the WFDT Project by Anna BOEHM, Thomas LUX

“…Conclusions: The content structure, integration of tasks, and examples will be retained for this and other case studies. …”
Get full text

Biological and urban environmental variables as correlates of adolescents' physical activity by Julio Brugnara Mello, Michael Duncan, Arieli Dias, Gabriel Bergmann, Anelise Gaya, Adroaldo Gaya

“…After this, to examine the interrelationship between biological, urban environment variables and PA in structural equation analysis. This was a cross-sectional study with an adolescents’ randomized sample. …”
Get full text

Cost Management at Higher Education Institutions – Cases of Bosnia and Herzegovina, Croatia and Slovenia by Martina Dragija Kostić, Tatjana Jovanović, Jelena Jurić

“…The research results confirm poorly conceptualised and structured reporting of accounting information for management purposes, offering several applicable platforms for creation of performance management approaches and strategies in the public sector. …”
Get full text

Impact of tube shapes on the energy storage and thermal-hydraulic performances of finned latent heat energy storage systems by Zihao Cheng, Juan Du, Shuao Jia, Chengxiang Xiao, Feng Jiao, Yuxiang Hong

“…This study suggests a novel polygonal tube LHTES system that combines the fins and tube wall into a single structure in order to increase the heat storage power, improve the system's heat transfer efficiency, and effectively enhance thermal conductivity to better meet the needs of industrial production. …”
Get full text

Helical Phase Inflation and Monodromy in Supergravity Theory by Tianjun Li, Zhijin Li, Dimitri V. Nanopoulos

“…In the model, inflation is driven by the phase component of a complex field whose potential possesses helicoid structure. We construct phase monodromy based on explicitly breaking global U(1) symmetry in the superpotential. …”
Get full text

Guide to evaluate the simulation integration into the Medicine degree study plan: its evaluation in Cienfuegos by Mabel Rocha Vázquez, Dunia María Chávez Amaro, Víctor René Machado Navarro, Norma Mur Villar

“…Its basis in the principles for the development of self-assessment and structuring by variables and indicators gives it novelty and responds to quality management.…”
Get full text

A Design Method of Inland River Channel Based on Hydrodynamic Response of Ship by ZHANG Lei, FENG Shaoxiong, TAN Kun, GUO Tao, SONG Chengguo, CHU Xiumin, MIAO Yang

“…The analyses of flow details and experiences of engineers are extensively used for the design of channel nowadays, without thorough consideration of the fluid-structure interaction between flow and ships. In this paper, an inland channel design method based on ship hydrodynamic response is proposed. …”
Get full text

Do we need mother tongue language maintenance in Aceh? Voices from the school setting by Mulyani Mulyani, Ika Kana Trisnawati, Syarfuni Syarfuni, Mulyadi Syahputra, Sariakin Sariakin, Rosdiana Rosdiana

“…Employing a mixed-methods research design, data was collected through surveys and semi-structured interviews. The survey was distributed via Google Forms to 217 schoolteachers selected through voluntary sampling in Aceh, while interviews were conducted with seven teachers who willingly participated in the study. …”
Get full text