Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson’s Disease? The Potential Role of Zolpidem in the Treatment of Parkinso... by Antonio Daniele, Francesco Panza, Antonio Greco, Giancarlo Logroscino, Davide Seripa

“…Since a high density of zolpidem binding sites is in the two main output structures of the basal ganglia which are abnormally overactive in PD (internal globus pallidus, GPi, and substantia nigra pars reticulata, SNr), it was hypothesized that in PD patients zolpidem may induce through GABAA receptors an inhibition of GPi and SNr (and, possibly, of the subthalamic nucleus also), resulting in an increased activity of motor cortical areas (such as supplementary motor area), which may give rise to improvement of motor symptoms of PD. …”
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The expanded theory of planned behavior for energy saving among academics in Romania, Bulgaria, Turkey, and Slovakia by Silvia Puiu, Sidika Ece Yilmaz, Mihaela Tinca Udriștioiu, Janka Raganova, Zhelyazka Raykova, Hasan Yildizhan, Arman Ameen

“…The research hypotheses were tested using partial least squares structural equation modelling. The findings show that individual factors (attitude and perceived behaviour control) influence the energy-saving intention of academics but not the organisational factors due to the weak identification with their universities. …”
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An Improved Form of 2D SPH Method for Modeling the Excavation Damage of Tunnels Containing Random Fissures by Xuhua Ren, Shuyang Yu, Jixun Zhang, Haijun Wang, Zhaohua Sun

“…The excavation damage of deep tunnels is one of the most important factors contributing to the failure of tunnel structures. In order to investigate the influence of tunnel shapes and fissure geometries, the kernel function in the traditional SPH method has been improved, which can realize the brittle fracture characteristics of particles and can be called the Improved Kernel of Smoothed Particle Hydrodynamics (IKSPH-2D). …”
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Research on Fatigue Model of Semi-Rigid Base Asphalt Pavement before and after Polymer Grouting by Bei Zhang, Xu Zhang, Yanhui Zhong, Xiaolong Li, Meimei Hao, Xianwei Sang, Xiaoliang Wang, Jianyang Liu

“…This study proposes a fatigue damage model for pavement and polymer materials and uses the finite element method to establish a three-dimensional numerical model of a semirigid base asphalt pavement structure. Moreover, it compares and analyzes the mechanical response and fatigue damage of this pavement before and after polymer repair. …”
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SerpensGate-YOLOv8: an enhanced YOLOv8 model for accurate plant disease detection by Yongzheng Miao, Yongzheng Miao, Wei Meng, Wei Meng, Xiaoyu Zhou, Xiaoyu Zhou

“…Key enhancements include the incorporation of Dynamic Snake Convolution (DySnakeConv) into the C2F module, which improves the detection of intricate features in complex structures, and the integration of the SPPELAN module, combining Spatial Pyramid Pooling (SPP) and Efficient Local Aggregation Network (ELAN) for superior feature extraction and fusion. …”
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Crafting the Path: Robust Query Rewriting for Information Retrieval by Ingeol Baek, Jimin Lee, Joonho Yang, Hwanhee Lee

“…In this paper, we propose a novel structured query rewriting method called Crafting The Path tailored for retrieval systems. …”
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Natural Gas Migration Pathways and Their Influence on Gas Hydrate Enrichment in the Qiongdongnan Basin, South China Sea by Tingna Zuo, Ren Wang, Yulin He, Wanzhong Shi, Jinqiang Liang, Litao Xu, Hao Du, Yan Deng, Xiaofeng Xu

“…The basin modeling results show the following: (1) Diapirs, fault structures, and fractures constitute the three main types of natural gas migration pathways that transport the thermogenic gas from the deep to shallow layers in the QDNB. (2) The three migration pathways impact hydrate enrichment in different ways. …”
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Balancing act: Europeans' privacy calculus and security concerns in online CSAM detection by Răzvan Rughiniş, Simona-Nicoleta Vulpe, Dinu Ţurcanu, Daniel Rosner

“…Drawing on theories of structuration and risk society, we analyze how individual agency and institutional frameworks interact in shaping privacy attitudes in high-stakes digital scenarios. …”
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Facebook addiction among medical students: prevalence and consequences by Eman Fouad Mohamed, Amany Elshabrawy Mohamed, Amira Mohamed Youssef, Mohammad Gamal Sehlo, Eman Seif Alnasr Soliman, Abdallah Saad Ibrahim

“…Methods Six-hundred twenty-seven students from the Faculty of Medicine, Zagazig University, at Egypt were included at this cross-sectional study. A semi-structured questionnaire designed by authors was used to collect sociodemographic data and data about academic performance and sleep. …”
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Model Predictive Control for an Aerial Tree-Pruning Robot Based on Alternating Direction Method of Multipliers by Changliang Xu, Zhong Yang, Hao Xu, Qiuyan Zhang, Dongsheng Zhou, Kaiwen Lu, Jiaming Han, Luwei Liao

“…In this article, an aerial tree-pruning robot with a novel structure is designed to improve the pruning operation efficiency and enhance the safety of the staff. …”
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Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023) by Hesham R. El-Seedi, Mohamed S. Refaey, Nizar Elias, Mohamed F. El-Mallah, Faisal M. K. Albaqami, Ismail Dergaa, Ming Du, Mohamed F. Salem, Haroon Elrasheid Tahir, Maria Dagliaa, Nermeen Yosri, Hongcheng Zhang, Awg H. El-Seedi, Zhiming Guo, Shaden A. M. Khalifa

“…Additionally, the review highlights the innovative strategies employed in the isolation, structural elucidation, and chemical modification of marine natural products to enhance their potency, selectivity, and pharmacological properties. …”
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Investigation of a Biochemical Model with Recycling in Case of Negative Cooperativity by Svetoslav G. Nikolov, Vassil M. Vassilev, Momchil I. Nenov

“…Thus, we obtain that three different dynamical conditions (regimes) take place: (1) structurally unstable, (2) the existence of an unstable limit cycle with an external stable limit cycle, and (3) the existence of a stable limit cycle with an external unstable limit cycle. …”
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Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis by Sunish Mohanan, Brian D. Cherrington, Sachi Horibata, John L. McElwee, Paul R. Thompson, Scott A. Coonrod

“…Citrullination can significantly affect biochemical pathways by altering the structure and function of target proteins. Five mammalian PAD family members (PADs 1–4 and 6) have been described and show tissue-specific distribution. …”
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Cellular and Molecular Mediators of Neuroinflammation in the Pathogenesis of Parkinson’s Disease by Sandeep Vasant More, Hemant Kumar, In Su Kim, Soo-Yeol Song, Dong-Kug Choi

“…Neuroinflammation is a host-defense mechanism associated with restoration of normal structure and function of the brain and neutralization of an insult. …”
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Facile Method for Obtaining Gold-Coated Polyester Surfaces with Antimicrobial Properties by M. Drobota, M. Butnaru, N. Vornicu, O. Plopa, M. Aflori

“…The morphological and structural analyses have shown a good adhesion of AuNps at treated film surfaces. …”
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Extraction of Protein-Enriched Fractions from Sunflower and Hemp Seeds: Composition and Colloidal Stability of Less Refined Fractions as a Function of Initial pH by Simone Bleibach Alpiger, Sandra Beyer Gregersen, Amanda May Ellermann, Tenna Ji Jing Dissing, Milena Corredig

“…These findings demonstrate that improving fractionation efficiency between proteins and oleosomes requires a better understanding of biomacromolecule interactions and their resulting functional colloidal structures, before full adoption of these new, less refined ingredients in food formulations.…”
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Optical genome mapping to decipher the chromosomal aberrations in families seeking for preconception genetic counseling by Kaili Yin, Mengmeng Li, Hanzhe Zhang, Jiazhen Chang, Qingwei Qi, Xiya Zhou, Jiangshan Guo, Yaru Wang, Xuequn Mao, Na Hao, Yulin Jiang

“…Abstract Optical genome mapping (OGM) offers high consistency in simultaneously detecting structural and copy number variants. This study aimed to retrospectively evaluate the efficacy and potential applications of OGM in preconception genetic counseling. …”
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Performance and Characterization for Blend Membrane of PES with Manganese(III) Acetylacetonate as Metalorganic Nanoparticles by H. Abdallah, M. S. Shalaby, A. M. H. Shaban

“…The scanning electron microscopy (SEM) images have displayed a typical asymmetric membrane structure with a dense top layer due to the migration of Mn(acac)3 nanoparticles to membrane surface during the phase inversion process. …”
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A Novel Hybrid GCN-LSTM Algorithm for Energy Stock Price Prediction: Leveraging Temporal Dynamics and Inter-Stock Relationships by Babak Amiri, Amirali Haddadi, Kosar Farajpour Mojdehi

“…By employing a graph structure derived from Dynamic Time Warping (DTW), the GCN captures inter-stock relationships, while the attention mechanism within the LSTM component refines the modelling of temporal dynamics, allowing the model to focus on the most relevant historical information. …”
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Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14α-Demethylase Inhibitors by Nafiz Öncü Can, Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Serkan Levent, Büşra Korkut, Yusuf Özkay, Zafer Asım Kaplancıklı, Ali Savaş Koparal

“…Due to anticandidal importance of azole compounds, a new series of benzimidazole-triazole derivatives (5a–5s) were designed and synthesized as ergosterol inhibitors. The chemical structures of the target compounds were characterized by spectroscopic methods. …”
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