Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy by Zheng Y, Williams GR, Hu R, Tong S, Xu J, Wang T, Zhang Y, Wu J, Li F, Cai Y, Zhu LM

“…Robust in vitro and in vivo data demonstrate the efficacy of this approach and CaO2@ZIF8:CUR@PAA as an anticancer platform, paving the way for nanomaterials in immune-triggered cancer therapy.Highlights: - A new calcium accumulation nanoplatform plays a role in activate antitumor immunity.- Double-locked structure slows down the premature decomposition of CaO2.- The platform allows Ca2+ and H2O2 to accumulate in tumor cells.- This leads to mitochondrial dysfunction, apoptosis, and M1 macrophage polarization.- Potent anti-tumor effects are seen both in vitro and in vivo.Keywords: Calcium ion load, controlled-release nanomaterials, two-layer protective shell, pH responsive drug release, reactive oxygen species, anti-cancer…”
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Computing the time-dependent activity rate using non-declustered and declustered catalogues – a first step towards time-dependent seismic hazard calculations for operational earthq... by D. Montiel-López, S. Molina, S. Molina, J. J. Galiana-Merino, J. J. Galiana-Merino, I. Gómez, I. Gómez, A. Kharazian, J. L. Soler-Llorens, J. A. Huesca-Tortosa, A. Guardiola-Villora, G. Ortuño-Sáez

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L’ensemble monumental du Pâtis à Vieillevigne (Loire-Atlantique) : un nouvel exemple de complexe sur cour laténien en Gaule by Yann Dufay-Garel, Marie Grall, Sandrine Paradis-Grenouillet, Rémy Wassong

“…The construction of the building’s load-bearing structure is homogeneous, with no signs of repair. …”
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Prevalence and drivers of malaria infection among asymptomatic and symptomatic community members in five regions with varying transmission intensity in mainland Tanzania by Gervas A. Chacha, Filbert Francis, Salehe S. Mandai, Misago D. Seth, Rashid A. Madebe, Daniel P. Challe, Daniel A. Petro, Dativa Pereus, Ramadhani Moshi, Rule Budodo, Angelina J. Kisambale, Ruth B. Mbwambo, Catherine Bakari, Sijenunu Aaron, Daniel Mbwambo, Stella Kajange, Samuel Lazaro, Ntuli Kapologwe, Celine I. Mandara, Deus S. Ishengoma

“…Demographic, anthropometric, clinical, parasitological, type of house, and socio-economic status (SES) data were captured using structured questionnaires. Associations between parasite prevalence and potential drivers were determined by logistic regression, and the results were presented as crude (cOR) and adjusted odds ratios (aOR), with 95% confidence intervals (CIs). …”
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THE PUBLIC DEBT OF UKRAINE: A NEW DIMENSION OF DYNAMICS AND ARCHITECTURE OF THE MODEL FRAMEWORK OF THE MANAGEMENT SYSTEM by Serhii Petrukha, Nina Petrukha, Roman Miakota

“…The purpose of the work is to provide a long-term assessment (up to 2029) of fiscal stability, taking into account the invariance of macroeconomic factors and forecasts - GDP growth rates, inflation, exchange rate and debt structure. To this end, two target levels of public debt have been used in the study: 82% of GDP (according to IMF forecasts) and 60% of GDP (according to the Maastricht Treaty). …”
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Transition to competent oral feeding in preterm infants: Analyzing timing and determinants by Gabriela Bolea Muguruza, Cristina de Frutos Martínez, M. Teresa Tamayo Martínez, Judith Martín Corral

“…Conclusions: Our findings highlight the importance of structuring the transition to oral feeding and identifying the most at-risk group, which in our study were infants with severe morbidity associated with prematurity, for the purpose of targeting potential interventions. …”
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Two Novel Compounds Isolated from the Marine Fungal Symbiont of Aspergillus unguis Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells: In vitro Study by Bashari MH, Agung MUK, Ariyanto EF, Al Muqarrabun LMR, Salsabila S, Chahyadi A, Rosandy AR, Afifah E, Afni M, Atmaja HE, Putri T, Utami F, Subhan B, Syafrizayanti, Andriani Y, Elfahmi

“…Subsequently, ethyl acetate extraction and isolation of chemical constituents produced was performed. The structures of the isolated compounds were identified using several spectroscopic methods, ie, UV, NMR, and mass spectrometry. …”
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Incidence of unintended pregnancies and pregnancy experience among adolescents living with perinatally-acquired HIV in West Africa: a mixed-method study by Désiré Lucien Dahourou, Clément Tisseron, Caroline Yonaba, Joël Djaha, Marie-Sylvie N’Gbeche, Corinne Moh, Kouakou Kouadio, Patricia Nindjin, François Eboua, Belinda Bouah, Karen Malateste, Jean-Claude Azani, Eulalie Kangah, Elisabeth Thio, Philippe Msellati, Julie Jesson, Valériane Leroy, for the IeDEA West-African Collaboration

“…We estimated the 18-month incidence rate of pregnancy per 100 woman-years (WY) among those older than 14 years at inclusion. In Abidjan, semi-structured interviews were also conducted with eight adolescents who became pregnant since their inclusion to report their pregnancy experience. …”
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Suspected Mpox Symptoms and Testing in Men Who Have Sex With Men in the United States: Cross-Sectional Study by Kaitlyn Atkins, Thomas Carpino, Amrita Rao, Travis Sanchez, O Winslow Edwards, Marissa Hannah, Patrick S Sullivan, Yasmin P Ogale, Winston E Abara, Kevin P Delaney, Stefan D Baral

“…This suggests targeted outreach is needed to reduce structural barriers to mpox services among GBMSM in rural areas, Black and GBMSM, and GBMSM living with HIV. …”
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Agricultural Drought Assessment using Remote Sensing Data (Case study: Tuyserkan County) by Maedeh Malmir, Kamran Shayesteh, Iman Pazhouhan

“…Introduction In recent years, with the growing significance of drought and climate change, there is an increasing need for a well-structured plan to implement effective management strategies and monitor drought conditions. …”
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Hepatitis B and C Viruses’ Infection and Associated Factors among Pregnant Women Attending Antenatal Care in Hospitals in the Amhara National Regional State, Ethiopia by Mulat Dagnew, Yihenew Million, Mucheye Gizachew, Setegn Eshetie, Gashaw Yitayew, Lakachew Asrade, Mulat Adefris, Feleke Moges, Moges Tiruneh

“…Data on sociodemographic and associated factors were collected using a structured questionnaire. Serum samples were tested for hepatitis B surface antigen (HBsAg) and anti-hepatitis C virus antibody (anti-HCV) using ELISA. …”
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Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against <i>Aspergillus</i> Species by Tatevik Sargsyan, Lala Stepanyan, Henrik Panosyan, Heghine Hakobyan, Monika Israyelyan, Avetis Tsaturyan, Nelli Hovhannisyan, Caterina Vicidomini, Anna Mkrtchyan, Ashot Saghyan, Giovanni N. Roviello

“…Given the rising concerns about antifungal resistance, these amino acid derivatives, with their unique bioactive structures, could serve as a novel class of therapeutic agents. …”
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Fracture-seepage characteristic zones of the overburden of extra-thick coal seams: Evolutionary patterns and their engineering applications by Xiangguo KONG, Tianshuo ZHAO, Haifei LIN, Pengxiang ZHAO, Xu WANG, Yuchu CAI, Pengfei JI, Di HE, Ke LI, Chuanyu XU

“…Objective and Methods Given that the overburden’s structure significantly influences pressure relief gas extraction, this study aims to explore the gas migration patterns of the overburden of thick coal seams during coal seam mining. …”
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Global biogeography of N₂-fixing microbes: <i>nifH</i> amplicon database and analytics workflow by M. Morando, J. D. Magasin, S. Cheung, S. Cheung, M. M. Mills, J. P. Zehr, K. A. Turk-Kubo

“…One widely used approach for understanding diazotroph diversity and biogeography is polymerase chain reaction (PCR) amplification of a portion of the <i>nifH</i> gene, which encodes a structural component of the <span class="inline-formula">N₂</span>-fixing enzyme complex, nitrogenase. …”
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Aides à la navigation, pratique de la navigation et construction des paysages maritimes en Atlantique du Nord-Est : quelques éléments de réflexion by Pascal Arnaud

“…The example of the Mediterranean highlights the extreme diversity of these structures that are visible from a great distance, sometimes identified by their inscription. …”
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Deep-Learning-Based Reconstruction of Single-Breath-Hold 3 mm HASTE Improves Abdominal Image Quality and Reduces Acquisition Time: A Quantitative Analysis by Felix Kubicka, Qinxuan Tan, Tom Meyer, Dominik Nickel, Elisabeth Weiland, Moritz Wagner, Stephan Rodrigo Marticorena Garcia

“…Compared with DL-HASTE-5 mm (1.10 × 10⁻⁵ ± 6.93 × 10⁻⁶), DL-HASTE-3 mm (1.56 × 10⁻⁵ ± 8.69 × 10⁻⁶) provided a significantly higher SNR Laplacian variance (<i>p</i> < 0.001) and sharpness sub-scores for the intestinal tract, adrenal glands, and small anatomic structures (bile ducts, pancreatic ducts, and vessels; <i>p</i> < 0.05). …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“… Buffaloes are excellent converters of highly fibrous feeds into edible products like milk and meat due to the rumen microbiome structure and their functionality. About 37– 44% of global methane emissions, mainly due to enteric fermentation of feeds by fibrolytic bacteria and formation of methane by methanogenic archaea, present in the rumen, is contributed by ruminants and a major source of methane production in the agriculture sector. …”
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Evaluasi TKTI Puri Saron Hotel Seminyak dengan Framework Cobit 5 by Norsa Yudhi Arso, Made Wisnu Antara Kesiman, Dewa Gede Hendra Divayana

“…Puri Saron Hotel Seminyak has in place a structured process to innovate and define strategy, define and convey each risk to the associated corporate value with the use of IT, and maximize ongoing operations within the scope of the organization.There is a significant gap between management capabilities current IT men and what to expect; Of the 11 domains and IT processes analyzed, 6 domains are two levels behind the expected, and 5 domains are one level behind the expected, and the findings of this study are presented in the form of a table of recommendations for improvement that can be implemented immediately at Puri Saron Hotel Seminyak. …”
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The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease by James P. Hardwick, Byoung-Joon Song, Paul Rote, Charles Leahy, Yoon Kwang Lee, Alexandra Rudi Wolf, Danielle Diegisser, Victor Garcia

“…Chronic liver diseases (CLDs) can lead to portal hypertension, which is a major cause of complications of cirrhosis. CLDs cause structural alterations across the liver through increased contents of extracellular matrix (ECM), driving dysfunction of liver sinusoidal endothelial cells (LSECs) alongside hepatic stellate cells (HSCs) and activated resident or infiltrating immune cells. …”
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Investigating the Role of Artificial Intelligence Enablers and Companies' Readiness in Adopting an Artificial Intelligence-integrated Customer Relationship Management System by Soheila Mohammadzadeh Vanestan, Rahim Abedi

“…To test the research hypotheses, structural equations were tested using a partial least squares approach, employing the third version of SMART-PLS software. …”
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