Proof of concept of fully automated adaptive workflow for head and neck radiotherapy treatments with a conventional linear accelerator by Gaia Muti, Marco M. J. Felisi, Angelo F. Monti, Chiara Carsana, Roberto Pellegrini, Edoardo Salmeri, Mauro Palazzi, Paola E. Colombo

“…The organs at risk (OARs) of the H&N district and five additional structures (air, fat, tissue, bone and patient’s exterior) subsequently used for the creation of the synthetic CT are auto-contoured with the Elekta ADMIRE® software. …”
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A Native LH1–RC–HiPIP Supercomplex from an Extremophilic Phototroph by Kazutoshi Tani, Ryo Kanno, Kenji V. P. Nagashima, Mai Kawakami, Naho Hiwatashi, Kazuna Nakata, Sakiko Nagashima, Kazuhito Inoue, Shinichi Takaichi, Endang R. Purba, Malgorzata Hall, Long-Jiang Yu, Michael T. Madigan, Akira Mizoguchi, Bruno M. Humbel, Yukihiro Kimura, Zheng-Yu Wang-Otomo

“…Here we present the cryo-EM structures of (1) a unique native Hlr. halophila triple-complex formed from light-harvesting (LH1), the reaction center (RC), and high-potential iron–sulfur protein (HiPIP) at 2.44 Å resolution, and (2) a HiPIP-free LH1–RC complex at 2.64 Å resolution. …”
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Cassava–soybean intercropping alleviates continuous cassava cropping obstacles by improving its rhizosphere microecology by Huixian Chen, Lixia Ruan, Sheng Cao, Wen He, Haixia Yang, Zhenhua Liang, Hengrui Li, Wanling Wei, Zhenling Huang, Xiu Lan

“…Phenol glucuronide, 2,3-butanediol, L-phenylalanine, deoxyguanosine and other carbohydrates, alcohols, purine nucleotides, and amino acids were significantly positively correlated with organic matter, available nitrogen, soil porosity, and pH.DiscussionTherefore, cassava–soybean intercropping can effectively alleviate the obstacles of continuous cassava cropping by affecting the accumulation of metabolites and microbial community structure in continuous cropping soil, thereby improving the adverse factors of severe soil acidification, soil compaction, and nutrient decline.…”
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Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis by Mengmeng Zhang, Hong Lv, Xiaoyin Bai, Gechong Ruan, Qing Li, Kai Lin, Hong Yang, Jiaming Qian

“…Compared with young colitis mice, DSS-induced colitis in the aged mice exhibited more severe inflammation, damaged mitochondrial structure and lower ATP levels in colonic tissues. …”
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A dextrorotatory residues-incorporated bioactive dodecapeptide against enterohemorrhagic Escherichia coli by Ping Zeng, Xuemei Yang, Kwok-Yin Wong, Sheng Chen, Kin-Fai Chan, Sharon Shui Yee Leung, Lanhua Yi

“…Results: Peptide zp39 presented an amphiphilic helical structure. It effectively inhibited the growth of E. coli O157:H7 at a concentration of 4 μmol/L in a bactericidal mode. …”
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Effects of Dietary Nano-Composite of Copper and Carbon on Antioxidant Capacity, Immunity, and Cecal Microbiota of Weaned Ira White Rabbits by Ying-Huan Zhou, Xiao-Ping Liu, Xiao-Ming Gu, Hai-Xuan Lv, Yun Yang, Zai-Xing Cai, Bin Di, Chang-Kang Wang, Yu-Yun Gao, Ling Jin

“…In addition, the metagenomic analysis of 16 S rRNA showed significant differences in the cecal microbial structure of weaned Ira white rabbits in the NCCC III group compared with the CON, NCCC I, and NCCC II groups (<i>p</i> < 0.05). …”
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A Wideband Chemical Survey of Massive Star-forming Regions at Subarcsecond Resolution with the Submillimeter Array by Charles J. Law, Qizhou Zhang, Arielle C. Frommer, Karin I. Öberg, Roberto Galván-Madrid, Eric Keto, Hauyu Baobab Liu, Paul T. P. Ho, Andrés F. Izquierdo, L. Ilsedore Cleeves

“…Overall, these results demonstrate that the SMA's wide bandwidth is a powerful tool to untangle the complex molecular gas structures associated with massive star formation.…”
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System Design and Optimisation Study on a Novel CCHP System Integrated with a Hybrid Energy Storage System and an ORC by Jie Ji, Zujun Ding, Xin Xia, Yeqin Wang, Hui Huang, Chu Zhang, Tian Peng, Xiaolu Wang, Muhammad Shahzad Nazir, Yue Zhang, Baolian Liu, Xiaoying Jia, Ruisheng Li, Yaodong Wang

“…The key idea of this study is designing a novel structure of a hybrid CCHP system and evaluating its performance. …”
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Two-dimensional semantic morphological feature extraction and atlas construction of maize ear leaves by Hongli Song, Hongli Song, Weiliang Wen, Weiliang Wen, Ying Zhang, Ying Zhang, Yanxin Zhao, Xinyu Guo, Xinyu Guo, Chunjiang Zhao, Chunjiang Zhao, Chunjiang Zhao

“…The morphological and structural variations observed in maize ear leaves are numerous and contribute significantly to the yield. …”
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Physico-Chemical Properties of Granular Sorbents Based on Natural Bentonite Modified by Polyhydroxocations of Aluminum and Iron (III) by Co-Precipitation by Bakytgul Kussainova, Gaukhar Tazhkenova, Ivan Kazarinov, Marina Burashnikova, Raigul Ramazanova, Yelena Ivashchenko, Bekzat Saurbayeva, Batima Tantybayeva, Ainur Seitkan, Gulsim Matniyazova, Khalipa Sadiyeva, Aisha Nurlybayeva, Aidana Bazarkhankyzy

“…It was found that modification of natural bentonite with iron (III) polyhydroxocations (mod. 1_Fe_5 GA) and aluminum (III) (mod. 1_Al_5 GA) by the “co-precipitation” method leads to a change in their chemical composition, structure, and sorption properties. It is shown that modified sorbents based on natural bentonite are finely porous (nanostructured) objects with a predominance of pores measuring 1.5–8.0 nm, with a specific surface area of 55–65 m²/g. …”
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Impact of gut microbial diversity on egg production performance in chickens by Liping Wu, Tao Zhang, Zhihua Luo, Huiyuan Xiao, Di Wang, Cailong Wu, Xinyan Fang, Jiawei Li, Jing Zhou, Junjie Miao, Hongli Tan, Yanan Wang, Qing Liu, Jianhua Huang

“…The results reveal significant differences in gut microbiota structure among chicken groups with varying egg production levels. …”
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Comparison of the adequacies of the OSCE and vOSCE to assess the competencies required under Brazilian medical curriculum guidelines: a multicenter study by Hervaldo Sampaio Carvalho, Maria do Carmo Barros Melo, Fabiana Maria Kakehasi, Priscila Menezes Ferri Liu, Fernanda Gontijo Minafra Silveira Santos, Ricardo Luiz de Melo Martins, Marilene Vale de Castro Monteiro, Marcelo Esteves Chaves Campos, Roberto Zonato Esteves, Matheus Belloni Torsani, Iolanda de Fátima Lopes Calvo Tiberio, Akihito Inca Atahualpa Urdiales, Andrea Mora De Marco Novellino, Rosiane Viana Zuza Diniz, Helena Ferreira Moura, Maria Alice de Vilhena Toledo, Célia Regina Machado Saldanha, Andrea Pedrosa Ribeiro Alves Oliveira, Patricia Zen Tempski, Itamar de Souza Santos, Milton de Arruda Martins

“…This study aimed to compare the objective structured clinical examination (OSCE) and the virtual objective structured clinical examination (vOSCE), based on expert opinion, as tools for assessing the competencies needed under medical curriculum guidelines in Brazil. …”
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Evaluation of ecological geological environment carrying capacity and analysis of driving mechanisms based on normal cloud model and geodetector model by Rongkun Dai, Changlai Xiao, Xiujuan Liang, Lin Jia, Yi Jia, Jiarui Yao, Weifei Yang, Jiang Zhang, Linzuo Zhang, Weifeng Li

“…Abstract The Luoyang area of the Yellow River Basin, as a typical resource-based city, its special industrial structure and complex geological structure make the ecological and geological environment of the area extremely fragile. …”
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Laryngeal recurrence sites in patients previously treated with transoral laser microsurgery for squamous cell carcinoma by P. Horwich, M. H. Rigby, C. MacKay, J. Melong, B. Williams, M. Bullock, R. Hart, J. Trites, S. M. Taylor

“…Abstract Background The laryngeal framework provides a natural barrier preventing tumour spread to extralaryngeal structures. Transoral laser microsurgery (TLM) for laryngeal squamous cell carcinoma (SCC) may violate these boundaries, altering the pathways of tumor spread for potential recurrences. …”
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Effect of Fish Meal Substitution with Black Soldier Fly (Hermetia illucens) on Growth Performance, Feed Stability, Blood Biochemistry, and Liver and Gut Morphology of Siamese Fight... by Zulhisyam Abdul Kari, Guillermo Téllez-Isaías, Noor Khalidah Abdul Hamid, Nor Dini Rusli, Khairiyah Mat, Suniza Anis Mohamad Sukri, Muhammad Anamul Kabir, Ahmad Razali Ishak, Nazri Che Dom, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Martina Irwan Khoo, Faizuan Abdullah, Md Shahjahan, Md Fazle Rohani, Simon J. Davies, Lee Seong Wei

“…The 13% BSFL diet group had an intact epithelial barrier in the goblet cell arrangement and a well-organized villus structure and tunica muscularis, compared to the other treatment groups. …”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

“…Of the 113 analogs designed, 93 demonstrated a more negative binding energy to the Sec61 channel compared to CADA. Structure-binding energy analyses were done to the top-binding analogs to show favorable structural modifications. …”
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AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease by Lulu Zhang, Yi Zheng, Mingyan Shao, Aiping Chen, Meiyi Liu, Wenlong Sun, Tianxing Li, Yini Fang, Yang Dong, Shipeng Zhao, Hui Luo, Juan Feng, Qi Wang, Lingru Li, Yanfei Zheng

“…Futher analysis of their structures using AlphaFold3 algorithms, yielded high-ranking scores of 0.97 and 0.93, respectively. …”
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Patient, Caregiver, and Provider Perspectives on Improving Provider-Patient Interactions in Hemodialysis: A Qualitative Study by Melanie D. Talson, Priscila Ferreira da Silva, Juli Finlay, Krista Rossum, Kaytlynn V. Soroka, Michael McCormick, Arlene Desjarlais, Hans Vorster, Rachelle Sass, Matthew James, Manish M. Sood, Allison Jaure, Neesh Pannu, Karthik Tennankore, Stephanie Thompson, Marcello Tonelli, Clara Bohm

“…Design: Multicentre qualitative study using focus groups and semi-structured interviews to elicit the perspectives of patients, caregivers, and health care providers. …”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…Background: This study investigated the association between photoreceptor structural restoration and visual function outcomes in patients undergoing surgery for closed macular holes (MHs). …”
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Anti-Inflammatory, Antithrombotic, and Antioxidant Properties of Amphiphilic Lipid Bioactives from Shrimp by Alexandros Tsoupras, Paschalis Cholidis, Dimitrios Kranas, Evangelia Aikaterini Galouni, Anna Ofrydopoulou, Pavlos Efthymiopoulos, Katie Shiels, Sushanta Kumar Saha, George Z. Kyzas, Chryssa Anastasiadou

“…Phenolic (TPC) and carotenoid (TCC) contents, antioxidant activities (DPPH, ABTS, FRAP assays), and biological effects on platelet-activating factor (PAF) and ADP-induced platelet activation were evaluated. Structural analyses were performed using ATR-FTIR spectroscopy, while LC-MS was used to elucidate the fatty acid composition and overall structure of polar lipids (PLs) present in shrimp TAC extracts. …”
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