MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban. by Hongyu Li, Jimiao Qiu, Chang Liu, Guobing Yu, Danyu Wu, Yichun Chu, Kai Wang

“…Changes in the structural integrity of the mouse heart were identified with HE and MASSON staining, while TUNEL staining was used to evaluate the TUNEL-positive cells of cardiomyocytes. …”
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Multi-step pre-treatment of rice husk for fractionation of components including silica by Shinnosuke Ishida, Shinji Kudo, Shinji Kudo, Shusaku Asano, Shusaku Asano, Jun-ichiro Hayashi, Jun-ichiro Hayashi

“…This study introduces a novel multi-step pre-treatment process to fractionate these components efficiently, enabling their comprehensive valorization.MethodsThe process begins with hydrothermal treatment, selectively extracting hemicellulose while preserving the structural integrity of other components. This is followed by an organosolv treatment using ethanol/water mixture, optimized to dissolve and extract organosolv lignin effectively. …”
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Drop-size-dependent effects in leading-edge rain erosion and their impact on erosion-safe mode operation by N. Barfknecht, D. von Terzi

“…<p>Leading-edge rain erosion poses a significant challenge for the wind turbine industry due to its detrimental effects on structural integrity and annual energy production. Developing effective mitigation strategies requires understanding the precipitation conditions driving erosion. …”
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In vitro sperm generation from immature mouse testicular tissue using plasma rich in growth factors by Seyyed Amir Moradian, Mansoureh Movahedin

“…Conclusions The findings suggest that 5%PRGF is a viable alternative to KSR in mouse testicular tissue cultures, promoting structural integrity and spermatogenesis up to the production of flagellated sperm. …”
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Optimization of Calcined Beans Pod Ash – Cement Blended Concrete Mix Using Taguchi Method by Oluwatoyin P Joseph, Adeola A Adedeji, Mokuolu A Olubunmi, Alomaja A Jonathan, Emmanuel O Ajadi

“…But improper mix design can result in inherent defects or local imperfections, which can significantly deteriorate the performance properties of concrete and jeopardize the structural integrity and durability of concrete structure. …”
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A Hybrid FEM-CNN for Image-Based Severity Prediction of Corroded Offshore Pipelines by Mohammad Fadzil Najwa, Muda Mohd Fakri, Abdul Shahid Muhammad Daniel, Aziz Norheliena, Mohd Mohd Hairil, Mohd Amin Norliyati, Mohd Hashim Mohd Hisbany

“…The combination of the Finite Element Method (FEM) with Convolutional Neural Networks (CNNs) presents a key breakthrough in the assessment of the structural integrity of offshore pipelines. The advantage of the standard FEM is in stress visualization, but it is time-consuming due to high computational analysis. …”
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Impact of Water-Cement Ratio and Desert Sand Powder on the Mechanical Properties of Eco-Self-Compacting Concrete by Said Zaouai, Farid Benmerioul, Abdelkadir Makkani, Ahmed Tafraoui, Rachid Rabehi

“…The findings reveal that decreasing the w/c ratio reduces porosity and improves the concrete's overall structural integrity. Capillary absorption tests indicate that while E-SCC with a 0.40 w/c ratio shows slightly higher initial absorption rates over the first two hours, it demonstrates better long-term performance over 24 hours compared to higher w/c ratios. …”
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Dynamic response of aerodynamic flutter of blooie line during gas drilling in mountain areas by Dianchen Liu, Peng Yang, Ke Deng, Shijie Tian, Hai Yan, Hongtao Li

“…This blockage is found to expose the blooie line to a significant risk of fracture, thereby threatening its structural integrity. The higher the gas production, the more severe the aerodynamic flutter of the blooie line. …”
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Analysis of the Feasibility of the OrthoNail Hybrid Intramedullary Implant in the Human Body with Respect to Material Durability by Dominika Grygier, Piotr Kowalewski, Mariusz Opałka, Jakub J. Słowiński, Mateusz Dziubek, Dariusz Pyka

“…Under axial compression, it withstood forces of up to 1400 N, maintaining structural integrity. Fatigue testing revealed resilience under dynamic loading conditions for over 1,000,000 cycles at a load of 500 N, with no mechanical failure or material degradation observed. …”
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Evaluating the Protective Effects of MitoQ and Antifreeze Protein III on Cryopreserved Canine Sperm by Abbas Farshad, Emilia Diel, Axel Wehrend

“…Cryopreservation can adversely affect sperm motility, structural integrity, and fertilization ability. This study investigated the effects of MitoQ and antifreeze protein III (AFP III) on frozen–thawed semen from eight adult dogs using a Tris–fructose extender. …”
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Design and Analysis of a Serial Manipulator for Pick and Drop Objects for Material Handling at Uiri Metal Forming Workshop. by Behangana, Abert

“…Static and dynamic analyses conducted via ANSYS Workbench validated the manipulator's structural integrity under a 50N load, confirming its resistance to significant deformation during operation. …”
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Improving the N-glycosylation occupancy of plant-produced IgG1 by engineering the amino acid environment at Asn297 by Kathrin Göritzer, Valentina Ruocco, Ulrike Vavra, Shiva Izadi, Omayra C. Bolaños-Martínez, Thareeya Phetphoung, Nuttapat Pisuttinusart, Waranyoo Phoolcharoen, Richard Strasser

“…The transient expression of trastuzumab and SARS-CoV-2 neutralizing IgG1 antibody COVA2-15 in N. benthamiana, with mutations such as Y300L, resulted in a notable improvement in glycosylation occupancy. While the structural integrity and monodispersity of the IgG1 variant remained unaltered, an improvement in thermal stability was observed. …”
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Structural conditions for relay ramp fault development on the edge of the collision wedge: a case study from the East Slovak Basin by Jacko, Stanislav, Ďuriška, Igor, Janočko, Juraj, Farkašovský, Roman, Thiessen, Alexander Dean

“…The relay ramps had four developmental phases: (a) initial crustal bending, (b) intact ramp formation with structural integrity disturbance, (c) breaching with crustal breakage, and (d) final fault growth. …”
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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…We hypothesized that the supplement group would increase, maintain, or show attenuated loss in hypothesized regions-of-interest (ROIs) while the placebo group would show age-related declines in brain structural integrity over the course of the trial. While results showed age-related declines for frontal and temporal gray and white matter volumes, as well as fornix white matter microstructure across both groups, only minimal differences were found between the supplement and placebo groups. …”
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Numerical Analysis on the Load Sharing Performance of Long-Short CFG Pile Composite Foundation Subjected to Rotation of Adjacent Retaining Wall by Bantayehu Uba Uge, Yuancheng Guo, Yunlong Liu

“…The soil movement disturbs the load sharing performance and structural integrity of cement-fly ash-gravel (CFG) pile composite foundations existing in the vicinity, which merits considerable research work. …”
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Insights into corrosion behavior of AlCrFeTi and AlCrFeTiY coating for fuel cladding in static and flowing liquid lead bismuth at 550°C by Jingyi Liang, Wei Zhang, Qingyu Li, Ke Zhao, Jun Xiao, Jijun Yang, Shaoyu Qiu, Sheng Huang

“…Double-layered compact oxide layers were formed on the surface of AlCrFeTi coating which consist of outer Fe/Cr oxide layer and inner Al/Ti oxide layer after exposure in static liquid lead bismuth for 2000 h, while uneven Fe/Cr oxide layers formed on AlCrFeTiY coating and the oxygen content significantly increase inside the coating, indicating the weaker antioxidant properties of AlCrFeTiY. Besides, structural integrity of AlCrFeTi was well preserved after erosion test in flowing lead bismuth (∼2 m/s) for 1000 h, localized bulges existed in eroded AlCrFeTiY coating. …”
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Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

“…We also observed progressive gray matter atrophy in broadly distributed gray matter regions and gradual micro-structural integrity damage in widespread white matter tracts along the AD continuum. …”
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High performance synthetic fiber-reinforced concrete mixed with nanoparticles: A proof-of-concept green railway sleeper product by Radhika Sridhar, Satjapan Leelatanon, Monthian Setkit, Thanongsak Imjai, Elhem Ghorbel, Boksun Kim

“…To further enhance structural integrity, the study incorporates fibers such as polypropylene fiber (PPF) and polyvinyl alcohol fiber (PVA) at a constant volume fraction of 0.5%. …”

Experimental Approach for the Evaluation of the Performance of a Satellite Module in the CanSat Form Factor for In Situ Monitoring and Remote Sensing Applications by Juan Sebastián Rodríguez, Andrés Yarce Botero, Diego Valle, Julián Gálvez- Serna, Francisco Botero

“…To know the dynamic response and ensure the structural integrity of the satellite module, shock, oscillation, and sinusoidal tests were applied through a shaker. …”
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Optimizing the gelation, structure, and thermal stability of alkali-induced duck egg white gels with calcium chloride by Pin-Chun Tseng, Wen-Yuan Yang, Yi-Chen Chen, Yen-Po Chen, Jia-Shian Shiu, Sheng-Yao Wang

“…The addition of calcium ions at appropriate concentrations enhances the gelation rate, structural integrity, and thermal stability of alkali-induced duck egg white gels and offers a safe and efficient method for utilizing surplus duck egg whites. …”
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