Showing 61 - 80 results of 101 for search '"structural biology"', query time: 0.04s Refine Results
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    Energetics of substrate transport in proton-dependent oligopeptide transporters by Balaji Selvam, Nicole Chiang, Diwakar Shukla

    Published 2024-12-01
    “…Despite advancements in structural biology, including cryogenic electron microscopy structures resolving PepTSo in different states, the molecular basis of peptide recognition and transport by PepTSo is not fully elucidated. …”
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    Serious issues with cryo-EM structures of human prothrombinase by James A. Huntington, Alexandre Faille, Fatma Isik Ustok

    Published 2025-01-01
    “…As is the norm in structural biology, the original paper was reviewed without access to the coordinates and maps, and it was therefore not possible for referees to assess the validity of the structures or their interpretations. …”
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    Characterization of the C-terminal tail of the Arc protein. by Melissa Boldridge, Jody Shimabukuro, Keith Nakamatsu, Christian Won, Chad Jansen, Helen Turner, Lei Wang

    Published 2020-01-01
    “…In this study, we characterized the C-terminal tail of Arc using integrated bioinformatic and structural biology techniques. We compared the sequences of Arc proteins in different mammal species and found that the amino-acid composition in the C-terminal tail region has a significantly higher degree of variation rate than the rest of the protein. …”
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    Antigen Delivery Platforms for Next-Generation Coronavirus Vaccines by Aziz A. Chentoufi, Jeffrey B. Ulmer, Lbachir BenMohamed

    Published 2024-12-01
    “…This review will (1) present the current state of antigen delivery platforms involving a multifaceted approach, including bioinformatics, molecular and structural biology, immunology, and advanced computational methods; (2) discuss the challenges facing the development of safe and effective antigen delivery platforms; and (3) highlight the potential of nucleoside-modified mRNA encapsulated in lipid nanoparticles (LNP) as the platform that is well suited to the needs of a next-generation pan-CoV vaccine, such as the ability to induce broad-based immunity and amenable to large-scale manufacturing to safely provide durable protective immunity against current and future Coronavirus threats.…”
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    A fiducial-assisted strategy compatible with resolving small MFS transporter structures in multiple conformations using cryo-EM by Pujun Xie, Yan Li, Gaëlle Lamon, Huihui Kuang, Da-Neng Wang, Nathaniel J. Traaseth

    Published 2025-01-01
    “…Abstract Advancements in cryo-EM have stimulated a revolution in structural biology. Yet, for membrane proteins near the cryo-EM size threshold of approximately 40 kDa, including transporters and G-protein coupled receptors, the absence of distinguishable structural features makes image alignment and structure determination a significant challenge. …”
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