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46481
Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine‐based approach in diverse healthcare systems
Published 2025-01-01“…The algorithm uses the Observational Medical Outcomes Partnership (OMOP) Common Data Model and queries structured and unstructured data elements, including diagnosis codes, laboratory measurements, and radiology and pathology modalities. …”
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46482
Cross-cultural adaptation and validation of the Spanish version of the Prevent for Work questionnaire
Published 2025-01-01“…Furthermore, the P4Wq showed good to excellent item response stability (weighted kappa = 0.75–0.96) and good for the total score (ICC = 0.98).ConclusionThe Spanish version of the P4Wq was face-valid and exhibited a similar structure as the original version. Additionally, good internal consistency and construct validity were found. …”
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46483
Triglyceride to high density lipoprotein cholesterol ratio and major adverse cardiovascular events in ACS patients undergoing PCI
Published 2024-12-01“…Patients in the high quartile TG/HDL-C category demonstrated significantly higher risks for MACE compared to those in the low quartile category, with hazard ratio (HR) [95%confidence interval (CI)] of 1.46 (1.17–1.83); conversely, they showed significantly lower risks for all-cause bleeding compared to their counterparts in the low quartile group, with HR (95%CI) of 0.72 (0.65–0.81). The structure of subgroup analyses remained robust and consistent, with gender being the sole factor interacting with TG/HDL-C specifically in relation to MACE events (P for interaction = 0.037). …”
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46484
Facile Synthesis of Novel Conducting Copolymers Based on N-Furfuryl Pyrrole and 3,4-Ethylenedioxythiophene with Enhanced Optoelectrochemical Performances Towards Electrochromic App...
Published 2024-12-01“…In this article, a series of novel conducting copolymers P(FuPy-<i>co</i>-EDOT) are prepared via cyclic voltammetry electropolymerization method by using N-furfuryl pyrrole (FuPy) and 3,4-ethylenedioxythiophene (EDOT) as comonomers. The molecular structure, surface morphology, electrochemical, and optical properties of the resulting copolymers are characterized in detail upon varying the feed ratios of FuPy/EDOT in the range of 1/1 to 1/9. …”
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46485
Strontium nitrate-dopped zinc oxide-loaded alginate gels with gentamicin for improved wound healing
Published 2025-01-01“…The linear viscoelastic region shows constant G’ and G” within the sample structure. In this study, we used three gels with different mixtures of ingredients: Gels A, B, and C contain sodium alginate (1% w/v) and 0.5 mL of Sr nitrate (4% w/v). …”
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46486
Computer-assisted discovery of natural inhibitors for platelet-derived growth factor alpha as novel therapeutics for thyroid cancer
Published 2025-01-01“…In this context, we proposed the PDGFRA inhibitors by an optimized structure-based drug design approach. We performed a virtual screening of metabolites derived from anticancer medicinal plants (Swertia chirayita, Myristica fragrans, and Datura metel) and successfully identified seven hits, namely cis-Grossamide K, Daturafoliside O, N-cis-feruloyltyramine, Maceneolignan H, Erythro-2-(4-allyl-2, 6-dimethoxyphenoxy)-1-(3, 4, 5-trimethoxyphenyl) propan-1, 3-diol, Myrifralignan C, and stigmasteryl-3-O-β-glucoside as potential PDGFRA inhibitors. …”
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46487
Virtual online consultations: advantages and limitations (VOCAL) study
Published 2016-01-01“…Data will be analysed and synthesised using a sociotechnical framework developed from structuration theory.Ethics approval City Road and Hampstead NHS Research Ethics Committee, 9 December 2014, reference 14/LO/1883.Planned outputs We plan outputs for 5 main audiences: (1) academics: research publications and conference presentations; (2) service providers: standard operating procedures, provisional operational guidance and key safety issues; (3) professional bodies and defence societies: summary of relevant findings to inform guidance to members; (4) policymakers: summary of key findings; (5) patients and carers: ‘what to expect in your virtual consultation’.Discussion The research literature on video consultations is sparse. …”
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46488
Impact of Economic Agglomeration on Carbon Emission Intensity and Its Spatial Spillover Effect: A Case Study of Guangdong Province, China
Published 2025-01-01“…The spatial spillover effect of the openness degree on carbon emission intensity was positive, while GDP per capita and industrial structure had negative effects. Further, the economic agglomeration effects of Guangdong Province increased the carbon emission intensity of major cities and smaller neighboring cities. …”
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46489
Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels
Published 2025-01-01“…Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain functional connectivity (FC) and consequently affects the levels of cognitive impairment in AD patients remains unknown. …”
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46490
Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime
Published 2025-01-01“…However, such models fail to reproduce the observed decrease in BLR size with increasing L / L _Edd at fixed optical luminosity, implying that gas density or BLR structure may systematically change with accretion rate.…”
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46491
Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity?
Published 2025-03-01“…Tests on the kidney showed damage to its tubules inside, with changes in their structure under a microscope. Closer examination revealed that the energy-producing parts of the cells, called mitochondria, were swollen and had fewer folds (cristae), which are essential for energy production. …”
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46492
Bug off or bug out: mapping flight secrets of Triatoma garciabesi (Hemiptera: Reduviidae) through climate, geography, and greenery
Published 2025-01-01“…Here, we aim to examine how phenotypic variation in flight-related traits is structured, determine the association between these traits and geographic distance, and identify the climatic, geographic, and/or vegetation cover variables that best explain the morphometric variation in flight-related traits.MethodsA total of 198 males of T. garciabesi from 24 populations in Argentina and Paraguay were included in this study, covering almost the entire T. garciabesi distribution range. …”
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46493
Laboratory Study of Local Scour Around an Array of Pile Groups in Clear-Water Scour Conditions
Published 2025-01-01“…Current-induced local scour around pile groups weakens the capacity of structures. In this paper, experimental tests of local scour around an array of 5 × 5 pile groups were conducted in a steady current in a hydraulic flume. …”
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46494
Application of Wasted Oolong Tea as a Biosorbent for the Adsorption of Methylene Blue
Published 2019-01-01“…The intraparticle diffusion of MB molecules into pore structures of wasted tea powder is the rate-limiting step for the adsorption process in this study. …”
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46495
Strength and Durability Performance of Hybrid Alkaline Clay Brick Waste –Coconut Shell Ash Cement
Published 2024-12-01“…Hybrid Alkaline Cement (HAC) has the potential to reduce carbon dioxide (CO2) and improve concrete structure. The durability of a hybrid alkaline mortar made from a mixture of calcined clay brick waste (CBW) and coconut shell ash (CSA) was compared with that of ordinary Portland cement (OPC) and pozzolanic Portland cement (PPC), which are the two common types of Portland cement. …”
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46496
Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates
Published 2025-01-01“…Despite the presence of contaminants, mainly in the form of albumin and lipoproteins, the material isolated with the 2,000 × g protocol contained red blood cell‐derived vesicular structures. It was reproducible, could predict the number of extracellular vesicles obtained with the 20,000 × g protocol and better discriminated between the three vesiculation cohorts than haemolysis at the legal expiry date of 6 weeks. …”
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46497
YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database
Published 2025-01-01“…Abstract Background The advancements in second-/third-generation sequencing technologies, alongside computational innovations, have significantly enhanced our understanding of the genomic structure of Y-chromosomes and their unique phylogenetic characteristics. …”
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46498
Seabed Acoustic Mapping Revealing an Uncharted Habitat of Circular Depressions Along the Southeast Brazilian Outer Shelf
Published 2025-01-01“…The modern maintenance of these structures could be due to low sedimentation regime areas shaped by biotic excavation.…”
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46499
Ion recognition enables fast Mg–Cl bond dissociation kinetics and better Mg plating/stripping reversibility
Published 2024-12-01“…The exposed electron-rich N/O sites and electron-deficient Co sites can regulate the adsorbing structure configuration of [Mg-Cl]+ complex ions by selectively bonding with the Mg2+ and Cl– through chemical coordination linkage, respectively. …”
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46500
Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China
Published 2025-01-01“…Methods From November 4, 2022, to January 15, 2023, HCWs in our hospital were enrolled to document clinical symptoms, prevention, and treatment for COVID‐19 using a structured questionnaire. Results A total of 1101 HCWs were included, with SARS‐CoV‐2 infection detected in 78.20% (861/1101) during the observation period. …”
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