Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage by Ji Eon Kim, Hyun Su Kim, Wonsik Kim, Eun Hae Lee, Soyeon Kim, Taewoo Kim, Eun-Ae Shin, Kyung-hee Pyo, Haesong Lee, Seo Hee Jin, Jae-Ho Lee, Soo-Min Byeon, Dong Joo Kim, Jinwook Jeong, Jeongwon Lee, Minjae Ohn, Hyojung Lee, Su Jong Yu, Dongyun Shin, Semi Kim, Jun Yeob Yoo, Seung-Chul Lee, Young-Ger Suh, Jung Weon Lee

“…We used comprehensive structure activity relationship analysis to identify TM4SF5-specific isoxazole (TSI)-based small molecules that inhibit TM4SF5-mediated effects. …”
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A preliminary investigation into self-compassion and compassion-based intervention for mental health in the performing arts by Courtney C. Walton, James N. Kirby, Sabrina McKenzie, Sabrina McKenzie, Caroline X. Gao, Caroline X. Gao, Rosemary Purcell, Rosemary Purcell, Simon M. Rice, Simon M. Rice, Margaret S. Osborne, Margaret S. Osborne

“…Descriptive pre-post data combined with thematic analysis of semi-structured interview transcripts identified performer perspectives of the compassion-based intervention.ResultsIn Study 1, 211 participants were included in the final cross-sectional analysis, which showed that the intention to be self-compassionate was associated with lower symptoms of depression and anxiety, and higher wellbeing, even while controlling for several key demographic and risk factors (stress, alcohol use, and body appreciation). …”
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Hepatitis B Birth Dose among Children in District 2 Hospital, Ho Chi Minh City, Vietnam: Prevalence and Associated Factors by Giao Huynh, Thanh Binh Nguyen, Ngoc Nga Cao, Minh Hoang Phan, Thi Bich Hop Dang, Thi Ngoc Han Nguyen

“…A prospective cross-sectional study between June and December 2017 recruited parents/caregivers of children aged 12–59 months who were randomly selected at the vaccination department in the District 2 Hospital. The structured questionnaire applied was to collect the characteristics of participants and check the vaccination schedule. …”
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Surface prereacted glass-ionomer particles incorporated into resin composites promote biocompatibility for restoration of subgingival dental defects by Yueyi Yang, Jing Huang, Xuchen Hu, Meiling Jing, Yujie Zhang, Chenci Xu, Wenduo Tan, Xiaoyu Liu, Chenguang Niu, Zhengwei Huang

“…Surface prereacted glass ionomer (S-PRG) is a novel glass particle characterized by a three-layered structure and the release of multiple ions with bioactive potential. …”
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The externalization of internal experiences in psychotherapy through generative artificial intelligence: a theoretical, clinical, and ethical analysis by Yuval Haber, Dorit Hadar Shoval, Inbar Levkovich, Dror Yinon, Karny Gigi, Oori Pen, Tal Angert, Zohar Elyoseph, Zohar Elyoseph

“…To address these challenges, we propose the SAFE-AI protocol, offering clinicians structured guidelines for responsible AI integration in therapy. …”
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En plaque meningioma of the temporal bone: A systematic review on the imaging and management of a rare tumor by Arianna Burato, Giuseppe Maruccio, Livio Presutti, Ignacio Javier Fernandez, Gabriele Molteni, Giulia Molinari

“…Magnetic Resonance Imaging (MRI) revealed dural enhancement (28 %), temporal hyperostosis (20 %), a clearly enhancing extra-axial mass (28 %), compression of the surrounding vasculo-nervous structures (8 %) and the possible involvement of the temporal lobe (8 %). …”
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Documentation of ethnoveterinary knowledge and alternative practices for cattle tick control in Sekhukhune District, Limpopo Province, South Africa by Confidence Semakane Phaahla, Jeremiah Leshweni Shai, Vincent Maduna, Resoketswe Charlotte Moropeng, Solomon Ramagoai Magano

“…In addition, a semi-structured questionnaire and a guided field survey were employed to collect data.ResultsA total of 250 participants, with an age range from 18 to over 60 years, were recruited. …”
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Association of contraception use and pregnancy intention with perinatal depression risk among Omani mothers—a longitudinal cohort study by Atika Khalaf, Atika Khalaf, Nawal Al Amri, Pernilla Ny, Rebecca Mathew

“…A significantly higher proportion (87.8%) of women with planned pregnancies were primiparous (p < 0.001). Besides family structure (core family, p = 0.025) and monthly income (1,000 OMR or below, p = 0.021), mothers who were pregnant for the first time (p < 0.001), and those who were primiparous (p < 0.001) did not use contraception. …”
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Monitoring changes of forest height in California by Samuel Favrichon, Jake Lee, Yan Yang, Yan Yang, Ricardo Dalagnol, Ricardo Dalagnol, Fabien Wagner, Le Bienfaiteur Sagang, Le Bienfaiteur Sagang, Sassan Saatchi, Sassan Saatchi, Sassan Saatchi

“…Mapping and monitoring the structure of these forests at high spatial resolution provides the necessary data to better manage forest health, mitigate wildfire risks, and improve carbon sequestration. …”
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One-Pot Synthesis and Enhanced Vis-NIR Photocatalytic Activity of NiTiO₃/TiO₂ Templated by Waste Tobacco Stem-Silks by Weidong Yuan, Xiaohong Chen, Yi Zhao, Ying Fang, Han Zhang, Daomei Chen, Jiaqiang Wang

“…The boosting photocatalytic activity has been shown to be attributed to efficient charge separation and transfer across a direct Z-scheme heterojunction between NiTiO₃ and TiO₂ and enhanced light-harvesting ability of special flaky structure reduplicated from tobacco stem-silks. This reported strategy provides a new idea for the multifunctional utilization of waste tobacco stem-silks and the synthesis of novel photocatalysts for the potential application in wastewater treatment.…”
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Biomimetic ECM nerve guidance conduit with dynamic 3D interconnected porous network and sustained IGF-1 delivery for enhanced peripheral nerve regeneration and immune modulation by Teng Wan, Qi-Cheng Li, Feng-Shi Zhang, Xiao-Meng Zhang, Na Han, Pei-Xun Zhang

“…However, utilising tailored biomimetic three-dimensional (3D) topological porous structures combined with multiple bio-effect neurotrophic factors to create environments similar to neural tissues, regulate local immune responses, and develop a supportive microenvironment to promote peripheral nerve regeneration and repair poses significant challenges. …”
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The dynamics of sea otter prey selection under population growth and expansion by Clinton B. Leach, Benjamin P. Weitzman, James L. Bodkin, Daniel Esler, George G. Esslinger, Kimberly A. Kloecker, Daniel H. Monson, Jamie N. Womble, Mevin B. Hooten

“…The absence of a spatial gradient in the size of prey captured late in the study suggests that feedbacks between the top‐down effects of sea otter foraging, sea otter dispersal processes, and local variation in habitat productivity may have homogenized the size structure of available prey across Glacier Bay.…”
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New Solitary Wave Solutions of the Lakshamanan–Porsezian–Daniel Model with the Application of the Φ⁶ Method in Fractional Sense by Hicham Saber, Hussien Albala, Khaled Aldwoah, Amer Alsulami, Khidir Shaib Mohamed, Mohammed Hassan, Abdelkader Moumen

“…According to this methodology, effective and accurate solutions for wave structures within various types can be produced in the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">FLPD</mi></semantics></math></inline-formula> model framework. …”
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Dutch Validation of the Self-Evaluation of Negative Symptoms Scale (SNS) by Tim van Brouwershaven, Anika Poppe, Gerdina Hendrika Maria Pijnenborg, André Aleman, Nynke Boonstra, Shiral Gangadin, Sonia Dollfus, Wim Veling, Stynke Castelein, Jan Alexander de Vos, Edith Liemburg, PHAMOUS-researchers, Lisette van der Meer

“…CFA confirmed the five-factor structure of the SNS. The SNS was significantly correlated (all <i>p</i> < 0.001) with the PANSS positive (r = 0.31), PANSS negative (r = 0.33), HoNOS (r = 0.37), FR (r = 0.27) and the ManSA (r = −0.40). …”
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Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma by Nan Li, Haiying Qin, Rosa Nguyen, Mitchell Ho, Ming Sun, Eytan Ruppin, Michael C Kelly, Yingying Cao, Reona Okada, Jeyshka M Reyes-González, Hannah G Stack, Charlie Seibert, Carol J Thiele

“…We developed a new chimeric antigen receptor (CAR) targeting glypican-2 (GPC2) and conducted iterative preclinical engineering of the CAR structure to maximize its anti-tumor efficacy before clinical translation.Methods We evaluated different GPC2-CAR constructs by measuring the CAR activity in vitro. …”
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Nutritional Profiling of Wild Edible Plants: Quantification of Macronutrients and Minerals via Energy Dispersive X-ray (EDX) Fluorescence Spectroscopy by Muhammad Ibrahim, Naveed Akhtar, Asghar Khan, Sara, Yasir Anwar, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy, Abdur Rauf, Yogesh Kumar Ahlawat, Nisha Sharma, Luciano de Almeida Lopes

“…Ethno-medicinal profiles were obtained through semi-structured interviews with local informants. Mineral elements were analyzed using Energy Dispersive X-ray Fluorescence (EDX) Spectroscopy. …”
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Retinal thickness and vascular density changes in Keratoconus: A systematic review and meta-analysis by Hadi Vahedi, Mirsaeed Abdollahi, Reza Moshfeghinia, Shima Emami, Navid Sobhi, Rana Sorkhabi, Ali Jafarizadeh

“…Conclusion: In KC patients, significant alterations in retinal structure and vascular density have been observed. …”
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Prevalence and Risk Factors of Helicobacter pylori Infection among Children Aged 1 to 15 Years at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda by Phoebe Aitila, Michael Mutyaba, Simon Okeny, Maurice Ndawula Kasule, Rashid Kasule, Frank Ssedyabane, Benson Okongo, Richard Onyuthi Apecu, Enoch Muwanguzi, Caesar Oyet

“…After obtaining informed consent from parents/legal guardians, illegible children who presented with gastrointestinal complaints at Holy Innocents Children’s Hospital were recruited; structured questionnaires were administered to the parents/guardians to collect information on sociodemographic data and risk factors of H. pylori infection. …”
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Organizational readiness for change towards implementing a sepsis survivor hospital to home transition-in-care protocol by Elaine Sang, Elaine Sang, Ryan Quinn, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Jiyoun Song, Jiyoun Song, Jiyoun Song, Karen B. Hirschman, Karen B. Hirschman, Karen B. Hirschman, Sang Bin You, Sang Bin You, Katherine S. Pitcher, Katherine S. Pitcher, Nancy A. Hodgson, Nancy A. Hodgson, Nancy A. Hodgson, Patrik Garren, Melissa O'Connor, Sungho Oh, Sungho Oh, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles

“…Post-acute care informants had a mean 4.39-unit higher ORIC score compared to hospital informants (p = 0.03).ConclusionsPost-acute care informants had higher organizational readiness of change than hospital informants, potentially attributed to differences in health policies, expertise, organizational structure, and priorities. These findings and potential inferences may inform sepsis survivor transition-in-care protocol implementation. …”
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Identifying Factors Influencing Urban Bus Drivers’ Distraction: A Qualitative Study in Tehran, Iran by Fatemeh Sadat Mirnajafi Zadeh, Mojtaba Khosravi Danesh, Ali Nahvi, Abbas Rahimi Foroushani, Mohammad Javad SheikhMozafari, Adel Mazloumi

“…Data were collected through semi-structured interviews with the drivers as well as on-site observations. …”
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