Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study. by Md Mostafa Kamal, Kazi Fahmida Haque Shantanu, Shamiha Tabassum Teeya, Md Motiar Rahman, A K M Munzurul Hasan, Douglas P Chivers, Tanveer A Wani, Atekah Hazzaa Alshammari, Mahesh Rachamalla, Francisco Carlos da Silva Junior, Md Munnaf Hossen

“…Finally, MD simulation revealed consistent fluctuation in RMSD and RMSF, consequently Rg, hydrogen bonds, and PCA in the mutant proteins compared with wild-type, which might alter the functional and structural stability of CTLA4 protein. The current comprehensive study shows how various nsSNPs in the CTLA4 gene can modify the structural and functional characteristics of the protein, potentially influencing the pathogenesis of diseases in humans. …”
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Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2 by Amr S. Abouzied, Saad Alqarni, Kareem M. Younes, Sanad M. Alanazi, Dana M. Alrsheed, Rawabi K. Alhathal, Bader Huwaimel, Akram M. Elkashlan

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Reduction of absorption of Ta2O5 monolayers through the suppression of structural defects by employing an appropriate ionic oxygen concentration by Lin Wang, Weili Zhang, Ruijin Hong, Kun Wang, Menglei Wang, Qinmin Wang, Kui Yi, Jianda Shao

“…In this study, Ta2O5 monolayers were deposited using an ion-assisted electron beam evaporation technique, and the weak absorption at 1064 nm, temperature rise, optical band gap, element content, and binding energy were tested and analyzed. The band structure and microdefects of the Ta2O5 films were characterized, and their correlation with the absorption properties was established. …”
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Obstructive sleep apnea and structural and functional brain alterations: a brain-wide investigation from clinical association to genetic causality by Kang Wu, Qiming Gan, Yuhong Pi, Yanjuan Wu, Wenjin Zou, Xiaofen Su, Sun Zhang, Xinni Wang, Xinchun Li, Nuofu Zhang

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Structural Formation, Evolution, and Genetic Mechanisms of Fault in Controlling Hydrocarbon Migration of Unconventional Rocks: A Case Study of Zhuangnan Fault by Jing Wang, Yongwei Guo, Youwei Cui, Ke Sun, Huili Chu

“…On the other hand, the present structure framework of Zhanhua sag was reconstructed by Zhuangnan fault zone. …”
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Structural Characterization of Polygonum divaricatum L. Polysaccharide and Its Inhibitory Effect on Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells by CUI Yanyan, YUAN Yongxu, GUO Mingkun, HE Wenbing, LI Ming, PEI Shichun, LI Dajun

“…(PSPDL). Methods: The structure of PSPDL was characterized using high-performance gel permeation chromatography (HPGPC), high-performance liquid chromatography (HPLC), Fourier transform-infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and nuclear magnetic resonance spectroscopy (NMR). …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…While the PC ratio per biliary structure (cilia ratio status, CRs) was similar between BA patients and controls, PC length was decreased in BA patients. …”
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Machine learning based QSAR and Molecular Dynamics simulations in the structural design and mechanism of action of imidazole derivatives with anti-melanoma activity by Rosalvo Ferreira de Oliveira Neto, Sérgio Ruschi Bergamachi Silva, Cintia Emi Yanaguibashi Leal, Edilson Beserra de Alencar Filho

“…Here, Artificial Intelligence algorithms were used to select molecular descriptors and build a QSAR model, highlighting structural characteristics related to enhanced molecular potency. …”
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Comparing the Structural and Physicochemical Properties of Highland Barley <i>β</i>-Glucan from Different Sources: A Focus on Color by Ping Yu, Xuemin Kang, Pengfei Liu, Zhengzong Wu, Yue Cheng, Bo Cui, Wei Gao

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A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins by Jun Ma, Ming Chen, Yujie Wang, Jiaying Li, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen

“…Within 10 min, the complex induced complete degradation of tertiary structure pockets composed of α-helices and β-sheets located at residues MET1-GLU23, TYR73-ARG93, and SER147-PRO157. …”
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Preparation of Chloro Penta Amine Cobalt(III) Chloride and Study of Its Influence on the Structural and Some Optical Properties of Polyvinyl Acetate by Nada K. Abbas, Majeed Ali Habeeb, Alaa J. Kadham Algidsawi

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Structural, elastic, electronic, magnetic and thermal properties of X3FeO4 (X = mg, ca and Sr) materials by Mohammed El Amine Monir, Abdelkarim Bendoukha Reguig, M. A. Ghebouli, K. Bouferrache, Faisal Katib Alanazi, M. Fatmi, H. Bouandas

“…The calculated elastic constants confirm their stability in the cubic structure. The electronic characteristics calculated using the GGA and GGA + U approaches prove that all these compounds are semi-metallic with a wide band gap (EHM) and a high Curie temperature (TC). …”
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Synthesis, Characterization, and DNA-Binding Kinetics of New Pd(II) and Pt(II) Thiosemicarbazone Complexes: Spectral, Structural, and Anticancer Evaluation by Simon N. Mbugua, Lydia W. Njenga, Ruth A. Odhiambo, Shem O. Wandiga, Mervin Meyer, Nicole Sibuyi, Roger A. Lalancette, Martin O. Onani

“…The compounds had low to moderate anticancer potency with their spectral and structural properties correlating with the corresponding anticancer activity profiles. …”
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Biodiversity and Structural Analysis of Woody Plant Species of Home Gardens in Basona Worana District, North Shoa Zone of Central Ethiopia by Almaz Woldeyohannes, Admasu Moges

“…The purpose of this study was to investigate the biodiversity and structure of woody plants of HGs in the Basona Worana district (BWD). …”
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Exopolysaccharides from camel milk-derived Limosilactobacillus reuteri C66: Structural characterization, bioactive and rheological properties for food applications by A.K.M. Humayun Kober, Mohamed Abdin, Athira Subhash, Shao-Quan Liu, Enes Dertli, Basim Abu-Jdayil, Pau-Loke Show, Mutamed Ayyash

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Design, synthesis, structural characterization, in vitro anticancer activity, and in silico studies of some new hydroxylated and fluorinated-substituted hydrazone derivatives by Reşit Çakmak, Eyüp Başaran, Ömer Erdoğan, Suraj N. Mali, Semiha Köprü, Haya Yasin, Shailesh S. Gurav, Giray Topal

“…In this study, novel hydroxylated and fluorinated-substituted hydrazone derivatives bearing an aromatic nitro moiety (2a-d and 3a-d) were designed as potential anticancer drug candidates, synthesized for the first time, and evaluated for their anticancer activity against chondrosarcoma (SW1353), a common primary malignant cartilage-forming tumor, neuroblastoma (SH-SY5Y), a type of brain cancer, and healthy (L929) cell lines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method for 24 h. The chemical structures of the target molecules were confirmed by FT-IR, 1D NMR (1H- and 13C- NMR, and APT), 2D NMR (COSY, HETCOR, and HMBC), and elemental analysis. …”
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Effect of Pitch Angle on Structural and Aerodynamic Characteristics of Vertical-Axis Wind Turbines (VAWTs) Using Leading-Edge Protuberance Blades by Karthikvel Elangovan, S. Nadaraja Pillai

“…An experimental investigation was carried out to understand the effects of LEP (leading-edge protuberance) blades on the structural characteristics of VAWTs. A series of experiments were performed on VAWTs with straight and LEP blades for a wide range of wind velocity (6 m/s to 20 m/s) and pitch angles (−20° to 20°), and the structural excitations on the VAWT structure were measured using a triaxial accelerometer in each case. …”
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Using airborne LiDAR and enhanced-geolocated GEDI metrics to map structural traits over a Mediterranean forestZenodo by Aaron Cardenas-Martinez, Adrian Pascual, Emilia Guisado-Pintado, Victor Rodriguez-Galiano

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The effect of sexual health literacy on sexual function mediated by sexual satisfaction and sexual self-efficacy: Structural equation modeling approach. by Mojdeh Banaei, Saeed Hosseini, Shiva Alizadeh, Nasibeh Roozbeh, Behnaz Jahanshahloo, Elham Ghasemi, Vida Ghasemi

“…A cross-sectional study was conducted using structural equation modeling (SEM) with 431 eligible women of childbearing age recruited from health centers in Asadabad city, Hamadan, Iran, from 2023 to 2024 through convenience sampling method. …”
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Retraction notice: Exploring the influencing factors of environmental deterioration: evidence from China employing ARDL–VECM method with structural breaks

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