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15641
Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology
Published 2025-02-01“…These observations also provide an opportunity for innovative vaccine development strategies employing ionizing radiation to disrupt the B. burgdorferi genome, while maintaining antigenic potency. …”
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15642
Surface functionalization of titanium implants with controlled-release glutathione conjugate for antioxidant and osteogenesis
Published 2025-01-01“…Altogether, the proposed strategy demonstrates the potential application of novel antioxidant Ti biomaterials to promote osteogenesis against oxidative stress.…”
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15643
Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree
Published 2023-05-01“…We expect soil types to affect both, functional traits in relation to resource acquisition strategy as already described at the interspecific level, and growth strategies due to resource limitations with reduced growth on poor soils. 3. …”
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15644
Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastoma
Published 2025-01-01“…These preclinical results suggest that combining VPA with NKG2D CAR-T therapy represents a promising strategy for improving glioblastoma treatment, warranting further clinical investigation.…”
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15645
USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer
Published 2025-02-01“…Conclusions: These data revealed the potential role of DGS/X-ray co-therapy in controlling ESCA resistance to radiotherapy by inhibiting the USP14/YAP1 axis, providing a candidate strategy for ESCA treatment.…”
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15646
Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants
Published 2025-12-01“…Background The development of bivalent or multivalent vaccines offers a promising strategy for combating SARS-CoV-2 mutations.Research design and methods In this phase 2 trial, conducted from 1 December 2021, to 25 July 2023, 392 unvaccinated adults aged ≥18 years were randomized to receive a primary series of two doses and a booster dose of SCTV01C, a bivalent protein SARS-CoV-2 vaccine.Results Geometric mean titers (GMTs) of neutralizing antibodies (nAb) against live Alpha, Beta, Delta, and Omicron showed 85.4-, 100.0-, 32.1-, and 9.8-fold increase from baseline on 28 days, and 49.4-, 55.3-, 5.7-fold increase against live Alpha, Beta, and Omicron on 90 days after primary series. …”
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15647
Three different methods for ZnO-RGO nanocomposite synthesis and its adsorption capacity for methylene blue dye removal in a comparative study
Published 2025-01-01“…Zinc oxide- reduced graphene oxide (ZnO-RGO) nanocomposite is used in this study as an adsorbent for the adsorption of methylene blue (MB) dye from an aqueous solution. An easy strategy was used for the synthesis of reduced graphene oxide nanoparticles (RGO), Zinc oxide nanoparticles (ZnO) and ZnO-RGO nanocomposite. …”
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15648
Personality and help-seeking for psychological distress: a systematic review and meta-analysis
Published 2025-01-01“…Procedures followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search strategy included two concepts: personality and help-seeking and was carried out on PubMed, Embase, Web of Science, and PsycINFO. …”
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15649
Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study
Published 2025-06-01“…Conclusions: A substantial proportion of postnatal women experience transient symptoms that are distinguishable from enduring symptoms through a refined two-stage screening strategy. This approach significantly improves referral efficiency and minimizes over-pathologization, enhancing clinical practice in perinatal mental health.…”
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15650
Hairy vetch influence on nitrous oxide and nitrate leaching losses during corn growing seasons in reduced and no-till systems
Published 2025-01-01“…We conclude that in soils with claypan and fragipans in humid climates, NT is not an effective strategy to decrease N2O-N fluxes. Hairy vetch benefits corn grain yield and supplements N but increases N loss through NO3-N leaching and N2O-N emissions.…”
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15651
Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study
Published 2024-12-01“…Conclusions These results suggest that intensified conditioning containing Dec might be a better strategy than standard myeloablative conditioning for adult patients with KMT2A-r leukemia undergoing allo-HSCT.…”
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15652
Effect of Physical Activity on Physical and Mental Health in Young Cancer Patients and Survivors: A Systematic Review of RCTs and CCTs
Published 2025-01-01“…Physical activity (PA) is increasingly recognized as a strategy to address physical, mental, cognitive, and social challenges faced by YCP and survivors (Braam et al., 2016). …”
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15653
Genetic investigations of autosomal recessive inherited ichthyosis impressed by fetal ultrasound: Exome sequencing and haplotype linkage analysis
Published 2025-01-01“…Disease-cause haplotyping by STR markers and ARMS-qPCR for PGT-M strategy were conducted in family 1. Linkage analysis in conjunction with STR was used in the first case, whereas unequal coverage of WES was deciphered with the inspiration of the second case a few years later. …”
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15654
Therapeutic Potential of <i>Cajanus cajan</i> (L.) <i>Millsp</i>. Leaf Extract in Modulating Gut Microbiota and Immune Response for the Treatment of Inflammatory Bowel Disease
Published 2025-01-01“…Overall, CCLE represents a promising natural product-based therapeutic strategy for treating IBD by restoring gut microbiota balance and modulating systemic immune responses.…”
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15655
Influence of Organ‐Specific Extranodal Involvement on Survival Outcomes in Stage IV Diffuse Large B‐Cell Lymphoma
Published 2025-01-01“…Notably, patients with spleen involvement appear to benefit from ASCT, suggesting that this strategy could be useful in this subgroup. Further prospective studies are needed to confirm and incorporate these findings into clinical practice.…”
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15656
Presenting the indigenous model of organizational self-leadership with an emphasis on training in non-governmental organizations
Published 2024-11-01“…Research methodology The strategy used in the current research is Data-based (Strauss and Corbin). …”
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15657
Presenting Iran's new economic diplomacy model with an export approach for neighboring countries with an emphasis on cultural and media diplomacy capacities
Published 2024-12-01“…Improving such a situation requires an export development strategy. The export development strategy is based on the premise that third world countries increase their export income using new methods in order to obtain capital (Atieh Kar et al, 2022). …”
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15658
Design and validation of consumer behavior model based on user-generated content in the banking industry
Published 2024-09-01“…In fact, in order for marketing strategies to have the ability to persuade customers to buy a product or service, a correct understanding of consumer behavior must first be created. …”
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15659
Telerehabilitation /
Published 2013Table of Contents: “…Introduction to Telerehabilitation -- Challenges and Trends Driving Telerehabilitation -- Telerehabilitation in the Military -- Nonverbal Communication and Telerehabilitation -- Telerehabilitation Interface Strategies for Enhancing Access to Health Services for Persons with Diverse Abilities and Preferences -- Telerehabilitation as a Means of Health-Care Delivery -- Implementation and Management of a Successful Telerehabilitation Program in Speech Language Pathology -- Speech Therapy Telepractice -- Applications in Teleaudiology -- Telehealth Opportunities in Occupational Therapy -- Tele-Ergonomics -- Electronic Record and Telerehabilitation -- Health Information Management and Rehabilitation: Moving Toward an Adequate Ethical Framework for Telerehabilitation -- Remote Accessibility Assessment System -- TeleAbilitation: GameAbilitation -- Virtual Reality Technologies and the Creative Arts in the Areas of Disability, Therapy, Health, and Rehabilitation -- Design, Construction, and Integration in Instrumented Walkways of a Portable Kit for the Assessment of Gait Parameters in Telerehabilitation -- Design and Construction of a Wearable Tool for Fall-Risk Detection in Telerehabilitation -- Professional Associations, State Licensure, and the Reimbursement of Telerehabilitation -- Making a Business Case for eHealth and Teleservices -- Speech-Language Pathology and Telerehabilitation.…”
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15660
Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trialResearch in context
Published 2025-01-01“…Summary: Background: Dual inhibition of cytotoxic T-lymphocyte associated protein 4 (CTLA-4) and programmed death ligand 1 (PD-L1) has been shown to be an effective treatment strategy in many cancers. We sought to determine the objective response rate of combination durvalumab (D) plus tremelimumab (TM) in parallel cohorts of patients with carefully selected rare cancer types in which these agents had not previously been evaluated in phase II trials and for which there was clinical or biological rationale for dual immune checkpoint inhibitor therapy to be active. …”
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