Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Employing zeolitic imidazolate framework-8 (ZIF-8) as a drug delivery platform, integrated within a temperature-sensitive injectable hydrogel, presents an intriguing strategy for the closure of various irregular wounds, modulation of inflammatory responses, and promotion of angiogenesis.Methods: Herein, ZIF-8 loaded with curcumin (Cur) combined with methylcellulose/carboxymethyl chitosan (MCC) thermosensitive hydrogel was described. …”
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Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins by Anna-Sophia Hartke, Cara S. Schreiber, Kristina Lau, Ivo Wiesweg, Inken Waltl, Ulrich Kalinke, Franziska Richter, Christopher Käufer

“…Furthermore, results from this study lend further support to the development of treatments aiming to reduce the impact of bacterial dysbiosis as a promising strategy to mitigate PD progression.…”
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Comparing short‐term outcome after implantation of the HeartWare® HVAD® and the Abbott® HeartMate 3® by Rene Schramm, Armin Zittermann, Michiel Morshuis, Michael Schoenbrodt, Ellen vonRoessing, Vera vonDossow, Andreas Koster, Henrik Fox, Kavous Hakim‐Meibodi, Jan F. Gummert

“…Patient matching was performed for age, sex, Interagency Registry for Mechanically Assisted Circulatory Support level at the time of implant, perioperative right heart failure, and implantation strategy, that is, bridge to transplant or destination therapy, as well as preoperative renal function, that is, as indicated by serum creatinine levels. …”
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Dietary supplementation with compound microecological preparations: effects on the production performance and gut microbiota of lactating female rabbits and their litters by Chengcheng Zhao, Youhao Li, Hui Wang, Ahamba Ifeanyi Solomon, Shuhui Wang, Xianggui Dong, Bing Song, Zhanjun Ren

“…Our findings highlight the potential of compound microecological preparations as an effective strategy for enhancing lactation performance, immune function, and antioxidant capacity in rabbits. …”
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Recombinant Lactococcus lactis Carrying IL-4 and IL-10 Coding Vectors Protects against Type 1 Diabetes in NOD Mice and Attenuates Insulitis in the STZ-Induced Model by Tatiane M. Preisser, Vanessa P. da Cunha, Mariana P. Santana, Vanessa B. Pereira, Denise C. Cara, Bianca M. Souza, Anderson Miyoshi

“…Therefore, our study demonstrates this innovative strategy provides immunomodulatory potential for further investigations in T1D and other autoimmune diseases.…”
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PdRu bimetallic nanoalloys with improved photothermal effect for amplified ROS-mediated tumor therapy by Yujia Liang, Shufang Ning, Mekhrdod S. Kurboniyon, Khaiyom Rahmonov, Zhengmin Cai, Shirong Li, Jinling Mai, Xiaojing He, Lijuan Liu, Liping Tang, Litu Zhang, Chen Wang

“…An emerging strategy in cancer therapy involves inducing reactive oxygen species (ROS), specifically within tumors using nanozymes. …”
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Acute Myocardial Infarction of the Left Main Coronary Artery Presenting with Cardiogenic Shock and Pulmonary Edema during Noncardiac Surgery by Sakae Takenaka, Takao Konishi, Tomoya Sato, Atsushi Tada, Takuya Koizumi, Yoshifumi Mizuguchi, Takahide Kadosaka, Ko Motoi, Yuta Kobayashi, Hirokazu Komoriyama, Yoshiya Kato, Miwa Sarashina, Kazunori Omote, Shingo Tsujinaga, Takuma Sato, Rui Kamada, Kiwamu Kamiya, Hiroyuki Iwano, Toshiyuki Nagai, Tatsuya Orimo, Hirofumi Kamachi, Akinobu Taketomi, Toshihisa Anzai

“…Early identification of the cause of hemodynamic instability during noncardiac surgery and invasive strategy are important for minimizing the myocardial injury and improving clinical outcomes in AMI of LMCA.…”
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Toward a circular carbon economy: Production of green C1 compounds through high-temperature CO2 electrolysis by Nan Zheng, Jing Zhu, Haitao Zhu, Jin Xuan, Haoran Xu, Meng Ni

“…It offers insights into system design and operational strategies aimed at enhancing the safety and efficiency of these conversions. …”
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Surgical treatment experience of seven cases of Berry syndrome by Zhangke Guo, Zhimin Li, Feng Tong, Song Bai, Xiaofeng Li

“…Two cases (2/7, 28.6%) of patients adopted the strategy of delayed sternal closure. The 6 surviving children were followed up for a period ranging from 3 to 132 months, with a median follow-up duration of 36 months. …”
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Identification of glutamine as a potential therapeutic target in dry eye disease by Xiaoniao Chen, Chuyue Zhang, Fei Peng, Lingling Wu, Deyi Zhuo, Liqiang Wang, Min Zhang, Zhaohui Li, Lei Tian, Ying Jie, Yifei Huang, Xinji Yang, Xiaoqi Li, Fengyang Lei, Yu Cheng

“…The present study suggests that glutamine metabolism plays a critical, previously unrecognized role in DED and proposes an attractive strategy to enhance glutamine metabolism by inhibiting the enzyme GLS1 and thus alleviating inflammation-driven DED progression.…”
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Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study by Roberta Bevilacqua, Elvira Maranesi, Marco Benadduci, Gabriella Cortellessa, Alessandro Umbrico, Francesca Fracasso, Giovanni Melone, Arianna Margaritini, Angela La Forgia, Pierpaolo Di Bitonto, Ada Potenza, Laura Fiorini, Carlo La Viola, Filippo Cavallo, Alessandro Leone, Andrea Caroppo, Gabriele Rescio, Mauro Marzorati, Amedeo Cesta, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Lorena Rossi

“…ConclusionsThis research underscores the promise of merging dance therapy with interactive exergaming on a robotic platform as an innovative strategy to enhance motor function, balance, gait, and overall quality of life for patients grappling with PD.…”
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Identification of Nontuberculous Mycobacteria in Patients with Pulmonary Diseases in Gyeongnam, Korea, Using Multiplex PCR and Multigene Sequence-Based Analysis by Min-Jeong Kim, Kyu-Min Kim, Jeong-Ih Shin, Jong-Hun Ha, Dong-Hae Lee, Jeong-Gyu Choi, Jin-Sik Park, Jung-Hyun Byun, Jung-Wan Yoo, Seokyong Eum, Myunghwan Jung, Seung Chul Baik, Woo Kon Lee, Hyung Lyun Kang, Min-Kyoung Shin

“…The results of this study suggest a strategy for rapid detection and accurate identification of species using two-step mPCR and multigene sequence-based analysis. …”
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Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised... by Luregn J Schlapbach, Barbara Brotschi, Kristen S Gibbons, Florian Zapf, Rebeca Mozun, Daphné Chopard, Philipp Baumann, Anika Adam, Vera Jaeggi, Beat Bangerter, Juerg Burren

“…Introduction Digital trials are a promising strategy to increase the evidence base for common interventions and may convey considerable efficiency benefits in trial conduct. …”
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A novel conjugated polymer synthesized via a noble metal-free catalyst in photothermal therapy of hepatocellular carcinoma mediated by second near-infrared (NIR-II) laser by Shengsheng Cui, Xinni Pan, Shanshan Fan, Cheng Cao, Yingao Jiao, Yanfei Fu, Jiaqi Niu, Shujin Lin, Jingmao Lao, Yanlei Liu

“…This work comprehensively investigates the photothermal properties of PPAPA and evaluates its efficacy in tumor PTT, demonstrating its potential as a novel and effective therapeutic strategy for cancer treatment, offering new hope for patients.…”
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In situ polymerized polyetherimide/Al2O3 nanocomposites with significantly improved capacitive energy storage performance at high temperatures by Li Tan, Jiufeng Dong, Li Li, Chengyuan Wang, Yuqi Liu, Yujuan Niu, Zizhao Pan, Liang Sun, Hong Wang

“…This work provides a scalable strategy for the preparation of dielectrics with both good processability and excellent high-temperature energy storage performance.…”
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A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses by Jin-Ha Song, Seung-Eun Son, Ho-Won Kim, Se-Hee An, Chung-Young Lee, Hyuk-Joon Kwon, Kang-Seuk Choi

“…Furthermore, we demonstrated that M2e-specific immune responses, difficult to induce with inactivated vaccines, can be effectively elicited with live vaccines, suggesting a strategy to enhance M2e immunogenicity in whole influenza virus vaccines. …”
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Biomimetic ECM nerve guidance conduit with dynamic 3D interconnected porous network and sustained IGF-1 delivery for enhanced peripheral nerve regeneration and immune modulation by Teng Wan, Qi-Cheng Li, Feng-Shi Zhang, Xiao-Meng Zhang, Na Han, Pei-Xun Zhang

“…Thus, biomimetic ECM NGCs offer a therapeutic strategy for peripheral nerve regeneration with promising clinical applications and transformation prospects to regulate immune microenvironments, promoting SC proliferation and differentiation with nerve axon growth.…”
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Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…An integrated transcriptomic and metabolomic analytical strategy was employed to dissect critical pathways and identify candidate genes that could dissect DE-induced pathogenesis. …”
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Lattice Stabilized and Emission Tunable Pure‐Bromide Quasi‐2D Perovskite for Air‐Processed Blue Light‐Emitting Diodes by Yangyang Guo, Penghui Yang, Fan Dong, Huixin Li, Jialiang Gao, Zeyi Cheng, Jiandong Wu, Yadong Xu, Hongyue Wang, Hongqiang Wang

“…Here, air‐processed pure‐bromide quasi‐2D blue perovskite films are achieved with stabilized lattice and tunable emission by interstitial doping of trivalent metallic cations. This strategy improves the formation energy of the perovskite lattice, promotes energy transfer between different n phases, and suppresses intrinsic electron‐phonon coupling in the perovskite films. …”
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Combined biochemical profiling and DNA sequencing in the expanded newborn screening for inherited metabolic diseases: the experience in an Italian reference center by Simona Fecarotta, Lorenzo Vaccaro, Alessandra Verde, Marianna Alagia, Alessandro Rossi, Chiara Colantuono, Maria Teresa Cacciapuoti, Patrizia Annunziata, Sara Riccardo, Antonio Grimaldi, Tonya Fusco, Rosa De Santis, Fernando Barretta, Lucia Albano, Daniela Crisci, Fabiana Vallone, Antonietta Tarallo, Marcella Cesana, Nicola Brunetti-Pierri, Giulia Frisso, Margherita Ruoppolo, Davide Cacchiarelli, Giancarlo Parenti

“…Advanced molecular technologies point to genomic sequencing as an alternative and feasible strategy for the screening of genetic diseases, including IMDs. …”
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