Family-focused intervention programme to foster adolescent mental health and well-being: protocol for a multicountry cluster randomised factorial trial (FLOURISH Phase 2) by Heather M Foran, Marija Raleva, Nina Heinrichs, Graham Moore, Yulia Shenderovich, Xiang Zhao, Judith Simon, Antonio Piolanti, Viorel Babii, Janina Mueller, Franziska Waller, Dennis Wienand, Swetha Sampathkumar, Ivo Kunovski

“…Effective and scalable interventions are urgently needed to address these challenges.Methods and analysis This protocol outlines a multicountry cluster randomised factorial trial, implemented according to the multiphase optimisation strategy (Phase 2), which evaluates the effectiveness and costs of three add-on components for the Parenting for Lifelong Health for Parents and Teens programme: adolescent mental health tools based on UNICEFs Helping Adolescents Thrive comics, adolescent peer support based on UNICEFs ‘I Support My Friends’ intervention and engagement booster designed to enhance attendance and programme completion through incentives. …”
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ABO-Incompatible Adult Living Donor Liver Transplantation in the Era of Rituximab: A Systematic Review and Meta-Analysis by Dipesh Kumar Yadav, Yong Fei Hua, Xueli Bai, Jianying Lou, Risheng Que, Shunling Gao, Yun Zhang, Ji Wang, Qinfen Xie, Muhammad Ibrahim Alhadi Edoo, Vikram Kumar Chutturghoon, Tingbo Liang

“…The primary aim of this study is to compare the short- and long-term outcomes between ABO-incompatible (ABOi) adult living donor liver transplantation (ALDLT) with rituximab prophylaxis and ABO-compatible (ABOc) ALDLT. Background. The strategy of ABOi liver transplantation (LT) was originated initially to increase the donor pool and to enable liver transplantation in emergency conditions. …”
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iRGD-Targeted Biosynthetic Nanobubbles for Ultrasound Molecular Imaging of Osteosarcoma by Liu T, Liang X, Liu W, Yang S, Cui T, Yan F, Li Z

“…Biocompatibility analysis showed no significant cytotoxicity of iRGD-sGVs to mice.Conclusion: Our study provides a new strategy for early diagnosis of osteosarcoma. Keywords: ultrasound molecular imaging, ultrasound contrast agents, gas vesicles, internalizing RGD, tumor imaging…”
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Cobalt (II) phthalocyanine derived Co3O4@HCNFs as highly effective bifunctional electrocatalysts for iodide redox couple reduction (IRR) and oxygen reduction reaction (ORR) by Ziyu Guo, Wenyu Gong, Jianing Guo, Mingxing Wu

“…This work is expected to provide a feasible strategy for exploring low-cost and highly effective bifunctional IRR/ORR electrocatalysts for DSCs and ZABs.…”
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Physiological and productivity responses of Tahiti acid lime grafted onto dwarfing rootstocks under different planting and mulching practices by Ana Júlia Borim de Souza, Mariângela Cristofani-Yaly, Patrícia Marluci da Conceição, Fernando Trevizan Devite, Marinês Bastianel, Paulo Vitor Sanches Romero, Pedro Henrique Barrio Padilha, Fernando Alves de Azevedo

“…Therefore, identifying the best varieties and management strategies for citrus groves has become a subject of increasing research. …”
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Effects of saffron-grape intercropping on saffron flower number and rhizosphere microbial community by Yuanyuan Tao, Guifen Zhou, Xingchang Zhang, Mengqing Feng, Liqin Li, Xiaodong Qian

“…These findings establish the foundation for the widespread application of saffron-grape intercropping and offer a promising strategy for increasing saffron yield.…”
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Medicarpin induces G1 arrest and mitochondria-mediated intrinsic apoptotic pathway in bladder cancer cells by Chen Yuan, Yin Liqi, Hao Mingxuan, Xu Wenkai, Gao Jixian, Sun Yuxin, Wang Qiao, Chen Shi, Liang Youfeng, Guo Rui, Zhang Jinku, Li Jinmei, Zhai Qiongli, Cheng Runfen, Wang Jiansong, Wang Haifeng, Yang Zhao

“…Hence, a novel therapeutic strategy in the clinical management of BC is urgently needed. …”
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Assessment of toxic response of Lactuca sativa to compost extracted from agri-food waste by Diego Andr´es Zapata-Gonz´alez, Juan Manuel Trujillo-Gonz´alez, Marco Aurelio Torres-Mora, Daniel Gonz´alez-Santamaria, Raimundo Jim´enez-Ballesta

“…Composting as a circular economy strategy that contributes to sustainable food security. …”
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Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection by Wei Dai, Xinmiao Chen, Xiaoting Xu, Zhefeng Leng, Wenwen Yu, Hui Lin, Huiying Li, Jie Lin, Zhangwei Qiu, Yuanrong Dai

“…Investigation of medical history is the best strategy for screening asymptomatic patients, especially young people, women, and people without coexisting disease, who are more likely to be asymptomatic when infected. …”
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Code-Switching in Algerian English as a Foreign Language Speakers’ Facebook Interactions: Exploring Functions and Motives by Saida Tobbi

“…This study underscores code-switching as a purposeful and multifaceted linguistic strategy that transcends conventional norms to achieve communicative goals and enhance stylistic expression. …”
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Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia by Abdilahi Ibrahim Muse, Abdilahi Ibrahim Muse, Mahdi Yonis Kayat, Mohamed Harir Aden, Jemal Beksisa Shuramu, Shikur Mohammed, Musse Ahmed Ibrahim, Musse Ahmed Ibrahim, Binyam Mohammedbirhan Berhe, Ahmed Abdi Kalinle, Sahardiid Ali Abdilahi

“…It can be prevented by two doses of the measles vaccine, either alone or in combination with measles-rubella (MR), which is a low-cost strategy for lowering morbidity and mortality among children.ObjectivesTo conduct spatial analysis of measles cases and vaccination coverage in the Somali region, Eastern Ethiopia.MethodsThis retrospective study was done by using public health emergency directorate measles data from 2022 to 2023 and four years (July 2019–July 2023) of vaccination data from district health information system version 2.36. …”
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Enhancing antibacterial photodynamic therapy with NIR‐activated gold nanoclusters: Atomic‐precision size effect on reducing bacterial biofilm formation and virulence by Chengyu Liu, Tenghui Tian, Yujia Shi, Meiqi Li, Le Hong, Jing Zhou, Jia Liu, Yuan Zhong, Xue Wang, Zhenyu Wang, Xue Bai, Lin Wang, Chunyan Li, Zhennan Wu

“…Moreover, this study highlights the unique role of ICG‐AuNCs in suppressing quorum sensing, virulence, and ABC transporters compared to their larger counterparts. This strategy demonstrates that atomic‐precision size effect of AuNCs paves the way for innovative approaches in antibacterial photodynamic therapy for infection control.…”
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3D‐Printed Metacarpal Prosthesis in the Treatment of Primary Osteosarcoma of the First Metacarpal: A Novel Surgical Technique by Xuanhong He, Leilei Tian, Chang Zou, Minxun Lu, Zhuangzhuang Li, Guy Romeo Kenmegne, Yitian Wang, Yi Luo, Yong Zhou, Li Min, Chongqi Tu

“…We tend to introduce a novel strategy to reconstruct the first metacarpal and restore the hand function. …”
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Protocol for a randomised ‘screen-and-treat’ Helicobacter pylori eradication trial in 14–18-years-old adolescents residing in three regions of Chile: effectiveness and microbiologi... by Ximena Aguilera, Camila Cabrera, Sergio George, Yalda Lucero, Beatriz Zabala Torres, Lilian Fernández, Nora Mamani, Anne Lagomarcino, Miguel O'Ryan

“…The purpose of this study is to determine the potential benefit of a ‘screen-and-treat’ strategy targeting persistently infected, asymptomatic adolescents. …”
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Blockchain-assisted improved interval type-2 fuzzy deep learning-based attack detection on internet of things driven consumer electronics by Rana Alabdan, Bayan Alabduallah, Nuha Alruwais, Munya A. Arasi, Somia A. Asklany, Omar Alghushairy, Fouad Shoie Alallah, Abdulrhman Alshareef

“…Finally, the bald eagle search (BES) model strategy improves the intrusion recognition rate. A series of investigations is accomplished to ensure the enhanced accomplishment of the ICOA-IT2FDL model. …”
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Fiber length distribution characterizes the brain network maturation during early school-age by Yanlin Yu, Qing Cai, Longnian Lin, Chu-Chung Huang

“…Our results suggest that the dual process of short- and long-range fiber changes reflects a cost-efficient strategy for optimizing network organization during this critical developmental stage.…”
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Dopamine‐conjugated extracellular vesicles induce autophagy in Parkinson's disease by Jae Hoon Sul, Sol Shin, Hark Kyun Kim, Jihoon Han, Junsik Kim, Soyoung Son, Jungmi Lee, Seung Hyun Baek, Yoonsuk Cho, Jeongmi Lee, Jinsu Park, Donghoon Ahn, Sunyoung Park, Leon F. Palomera, Jeein Lim, Jongho Kim, Chanhee Kim, Seungsu Han, Ka Young Chung, Sangho Lee, Tae‐in Kam, Yunjong Lee, Jeongyun Kim, Jae Hyung Park, Dong‐Gyu Jo

“…These findings collectively indicate that surface modification of EVs with dopamine presents a potent strategy for targeting dopaminergic neurons in the brain. …”
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Effects of high-pressure homogenization on phenolics profile, antioxidant activity, α-glucosidase inhibitory activity, and insulin resistance of peach juice during simulated gastro... by Yijin Peng, Shenke Bie, Shengbao Cai, Linyan Zhou, Chaofan Guo

“…These findings highlighted HPH as an innovative strategy for developing functional fruit-based beverages with enhanced nutritional and therapeutic value.…”
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Active biomonitoring in streams by using multimarker approaches of mussels by T. Ukasha, N.U.H. Faisal, B.K. Adji, A.P. Nugroho

“…This active biomonitoring strategy identified sensitive and specific biomarkers for the presence of metal and pesticide contaminants in stream ecosystems. …”
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Disturbed shear stress promotes atherosclerosis through TRIM21‐regulated MAPK6 degradation and consequent endothelial inflammation by Feng Wang, Shu‐Yu Wang, Yue Gu, Shuai Luo, Ai‐Qun Chen, Chao‐Hua Kong, Wen‐Ying Zhou, Li‐Guo Wang, Zhi‐Mei Wang, Guang‐Feng Zuo, Xiao‐Fei Gao, Jun‐Jie Zhang, Shao‐Liang Chen

“…Conclusions Our study illuminates the advantages of MAPK6 in decelerating plaque progression, highlighting the potential of safeguarding MAPK6 as a novel therapeutic strategy against atherosclerosis. Key points Disturbed flow activates the ubiquitin‒proteasome degradation pathway of MAPK6 in endothelial cells, which is contingent on the binding of the ubiquitin ligase TRIM21 to MAPK6. …”
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