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15061
Costs analysis of integrating group interpersonal therapy into HIV care services in Senegal
Published 2025-01-01“…The scenario analysis also illustrated the importance of parameters like the screening strategy, training activities, and allocation to cover transport costs mobilized by participants. …”
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15062
Selective light olefin synthesis with high ethylene abundance via CO2 hydrogenation over (Ga-In)2O3/SSZ-13 catalysts
Published 2025-01-01“…The findings presented here provide a strategy to tune CO2 hydrogenation product distributions toward specific target products.…”
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15063
Controllable synthesis of nonlayered high-κ Mn3O4 single-crystal thin films for 2D electronics
Published 2025-01-01“…Here, we report a hydrate-assisted thinning chemical vapor deposition (CVD) technique to grow manganese oxide (Mn3O4) single crystal nanosheets, enabled by a strategy to minimize the substrate lattice mismatch and control the growth kinetics. …”
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15064
Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis
Published 2025-01-01“…Besides, inhibiting TRIB3 to turn “cold tumor” hot has also been proved to be an effective therapeutic strategy for BC. Thus, this study aim to find drugs that can bind to TRIB3 to inhibit BC progression, and further elucidate its mechanism.MethodsThe possible inhibitors of TRIB3 were screened by high-throughput molecular docking, CETSA, and CO-IP assay. …”
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15065
Cannabinoid type-1 receptors in CaMKII neurons drive impulsivity in pathological eating behavior
Published 2025-02-01“…Methods: We applied a genetic strategy to reconstitute cannabinoid type-1 receptor (CB1) expression at functional levels specifically in CaMKII+ neurons (CaMKII-CB1-RS) and adipocytes (Ati-CB1-RS), respectively, in a CB1 deficient background. …”
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15066
Developing and Assessing a Scalable Digital Health Tool for Pretest Genetic Education in Patients With Early-Onset Colorectal Cancer: Mixed Methods Design
Published 2025-01-01“…ConclusionsThe findings revealed that Nest-CRC is a promising strategy for facilitating pretest education and promoting GT. …”
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15067
OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines
Published 2019-01-01“…Finally, we will discuss how system biology “OMICs” data can be used to design bioinformatic tools to predict the vaccination outcome providing genetic and molecular “signatures” of protective immune response. This strategy may soon enable identification of signatures highly predictive of vaccine safety, immunogenicity, and efficacy/protection thereby informing personalized vaccine interventions in vulnerable populations.…”
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15068
Influence of religion and spirituality on head and neck cancer patients and their caregivers: a protocol for a scoping review
Published 2025-01-01“…A comprehensive search strategy will include Embase, CINAHL, Scopus, and APA PsycINFO. …”
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15069
A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial
Published 2023-12-01“…Objective: Our study seeks to test a non-physician led virtual self-management implementation strategy to reduce ASCVD risk among people living with HIV (PWH). …”
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15070
The change rule of smoke dispersion and temperature evolution in fires within lithium iron phosphate energy storage prefabricated cabin
Published 2025-01-01“…The research results in the article can provide theoretical guidance for the distributed deployment strategy in energy storage prefabricated cabin and fire safety design of monitoring and warning devices.…”
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15071
Ultrasound outcomes and surgical parameters of the double-layer purse-string uterine closure technique in cesarean delivery: a systematic review and meta-analysis of randomized tri...
Published 2025-02-01“…Results A total of 353 studies were identified through the search strategy, with 8 studies included in the analysis. …”
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15072
Establishment of a Breeding Approach Combined with Gamma Ray Irradiation and Tissue Regeneration for Highbush Blueberry
Published 2025-01-01“…This study introduces a mutation breeding strategy for the highbush blueberry cultivar <i>Vaccinium corymbosum</i>. …”
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15073
Melatonin Reverses the Loss of Stemness Induced by TNF-α in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression
Published 2019-01-01“…Our results also provide a practical strategy for the application of BMMSCs in tissue engineering and cell therapy.…”
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15074
Real world federated learning with a knowledge distilled transformer for cardiac CT imaging
Published 2025-02-01“…Our two-step semi-supervised strategy distills knowledge from task-specific CNNs into a transformer. …”
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15075
PD-L1 positive platelets mediate resistance to immune checkpoint inhibitors in patients with colorectal cancer
Published 2025-01-01“…Clinical combination treatment with ICIs and antiplatelet agents may be an effective therapeutic strategy for treating CRC.…”
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15076
Tuberculosis screening among cough suppressant buyers in pharmacies and drug outlets in Guinea: a cross-sectional study
Published 2024-12-01“…We evaluated an intensified TB case finding strategy in Guinea which targeted customers who bought cough suppressants from pharmacies or drug outlets.Methods We involved 25 pharmacies and 25 drug outlets in Matoto, Conakry, Guinea. …”
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15077
Real-world effectiveness of intravenous belimumab in adults with systemic lupus erythematosus: results of the observational OBSErve study in the Russian Federation
Published 2025-01-01“…Conclusions Patients with SLE receiving IV belimumab for 6 months in real-world settings in the Russian Federation experienced overall clinical improvements and reductions in glucocorticoid use, which is an important long-term strategy of SLE treatment.…”
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15078
Exploring the Potential of SGLT-2 Inhibitors in Cancer Treatment: Mechanisms, Preclinical Findings, and Clinical Implications
Published 2025-01-01“…Conclusions SGLT-2 inhibitors represent a novel therapeutic strategy in oncology, with potential to improve outcomes in combination with traditional therapies. …”
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15079
USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression
Published 2025-01-01“…Downregulation of USP39 effectively suppressed lung cancer growth, and therefore targeting USP39 provides novel therapeutic strategy to treat lung cancer.…”
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15080
Determination of Sequential Well Placements Using a Multi-Modal Convolutional Neural Network Integrated with Evolutionary Optimization
Published 2024-12-01“…Moreover, the M-CNN-optimized well placement strategy yields a substantial 47.40% improvement in field cumulative oil production compared to the original configuration. …”
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