Non-Linear Biomechanical Evaluation and Comparison in the Assessment of Three Different Piece Dental Implant Systems for the Molar Region: A Finite Element Study by Jesus Alejandro Serrato-Pedrosa, Ignacio Villanueva-Fierro, Rodrigo Arturo Marquet-Rivera, Rosa Alicia Hernández-Vázquez, Salvador Cruz-Lopez, Verónica Loera-Castañeda

“…This biomechanical approach could provide a promising strategy for predicting micro-strains and micromotion in implant system pieces and geometries. …”
Get full text

Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis by Xinyan Hao, Yucheng Tang, Wenjie Xu, Ming Wang, Jiayi Liu, Yongjiang Li, Jun He, Yanjin Peng, Pengcheng Sun, Dehua Liao, Xiongbin Hu, Tiantian Tang, Min Zhou, Ruyue Han, Jiemin Wang, João Conde, Daxiong Xiang, Junyong Wu

“…A notable activation of immune cells was observed within tumors and lymph nodes, indicative of a synergistic effect of chemotherapy and immunotherapy, underscoring its potential as a safe and efficacious therapeutic strategy against GBM.…”
Get full text

“Ashamed of being seen in an HIV clinic”: a qualitative analysis of barriers to engaging in HIV care from the perspectives of patients and healthcare workers in the Daraja clinical... by Elialilia S. Okello, Robert N. Peck, Benson Issarow, Godfrey Kisigo, Kelvin Abel, Donati Malibwa, Severin Kabakama, Marco Charles, Myung Lee, Thomas Rutachunzibwa, Daniel Fitzgerald, Philip Ayieko, Heiner Grosskurth, Lisa R. Metsch, Saidi Kapiga

“…The Daraja intervention, a context-tailored case management strategy implemented and tested through a randomized trial in Tanzania, was associated with improved HIV clinic linkage, retention, and ART initiation and adherence. …”
Get full text

USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins by Xu Y, Li J, Qiu Y, Wu F, Xue Z, Liu B, Fan H, Zhou Y, Wu Q

“…This study highlights the potential of sEVs-loaded scaffolds as a promising strategy for scarless vaginal repair following vaginoplasty, offering a novel approach for regenerative medicine with significant translational potential for clinical application. …”
Get full text

Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice by Rose Hilal, Marine Poittevin, Adrien Pasteur-Rousseau, Adrien Cogo, Gabrielle Mangin, Marie Chevauché, Yasmine Ziat, José Vilar, Jean-Marie Launay, Jean-François Gautier, Dong Broquères-You, Bernard I. Levy, Tatyana Merkulova-Rainon, Nathalie Kubis

“…If confirmed, this rapid, noninvasive bedside cell therapy strategy could be applied to stroke patients at the acute phase.…”
Get full text

Biomineralized PEEK cages containing osteoinductive CaP bioceramics promote spinal fusion in goats by Qiujiang Li, Bowen Hu, Linan Wang, Lei Wang, Cong Feng, Zhuang Zhang, Zhipeng Deng, Yang Xiao, Bo Yuan, Xiangdong Zhu, Xiangfeng Li, Xi Yang, Yueming Song, Xingdong Zhang

“…In this study, a novel strategy for preparing bioactive biomineralized PEEK cages was developed using a unique combination of osteoinductive CaP bioceramic fillings in the cage window, acid sulfonation and simulated body fluid incubation. …”
Get full text

Factors associated with Physical Activity Counseling by Health Workers Questionnaire: construction, validation and reliability by João Miguel de Souza Neto, Sanderson Soares da Silva, José Cazuza de Farias Júnior, Filipe Ferreira da Costa

“…In the third step, a pilot study was carried out with 20 professionals (doctors, nurses and community health agents) from the Joao Pessoa, Paraíba Family Health Strategy. In the last step, reliability index was assessed among a sample of 53 health workers from five health units. …”
Get full text

Atmospheric reductive catalytic fractionation of lignocellulose integrated with one-pot catalytic conversion of carbohydrate yielding valuable lignin monomers and platform chemical... by Meng-Ying Liu, Zhe-Hui Zhang, Xue-Qi Wang, Qian Sun, Chen Zhang, Yu Li, Zhuohua Sun, Katalin Barta, Feng Peng, Tong-Qi Yuan

“…Herein, taking advantage of the “lignin first” strategy, corn straw is converted to valuable chemicals including lignin monomers, furfural and 5-methoxymethylfurfural via a two steps process. …”
Get full text

Does music counteract mental fatigue? A systematic review. by Cong Ding, Soh Kim Geok, He Sun, Samsilah Roslan, Shudian Cao, Yue Zhao

“…Several studies have investigated strategies to counteract mental fatigue. However, potential health risks and contextual restrictions often limit these strategies, which hinder their practical application. …”
Get full text

Sustained release of miR-21 carried by mesenchymal stem cell-derived exosomes from GelMA microspheres inhibits ovarian granulosa cell apoptosis in premature ovarian insufficiency by Xiaofei Zhang, Linzi Ma, Xiaotong Liu, Xingyu Zhou, Ao Wang, Yunhui Lai, Jun Zhang, Ying Li, Shiling Chen

“…These findings provide a novel and promising treatment strategy for POI patients.…”
Get full text

Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study by Bianca Uliana Picolo, Nathália Rabello Silva, Mário Machado Martins, Hebréia Oliveira Almeida-Souza, Letícia Cristina Machado de Sousa, Richard Costa Polveiro, Luiz Ricardo Goulart Filho, Robinson Sabino-Silva, Vivian Alonso-Goulart, Luciana Saraiva da Silva

“…Proteomics using saliva is a key strategy for identifying potential disease biomarkers.MethodsWe analyzed the untargeted proteomic profiles of saliva samples from 20 individuals with end-stage kidney disease (ESKD) (n = 10) and healthy individuals (n = 10) using liquid chromatography–tandem mass spectrometry (LC–MS/MS) to identify potential biomarkers for CKD. …”
Get full text

Spatially Resolved Multiomics: Data Analysis from Monoomics to Multiomics by Changxiang Huan, Jinze Li, Yingxue Li, Shasha Zhao, Qi Yang, Zhiqi Zhang, Chuanyu Li, Shuli Li, Zhen Guo, Jia Yao, Wei Zhang, Lianqun Zhou

“…On the basis of the spatial multiomics technology, we propose a data integration strategy with cross-platform, cross-slice, and cross-modality. …”
Get full text

Malva neglecta essential oil: A promising approach for bio-preserving mayonnaise and assessing variable correlations through principal component analysis and heat map by Amin Abbasi, Hedayat Hosseini, Hadi Pourjafar, Samaneh Moradi, Saeedeh Shojaee-Aliabadi

“…The MNEO-based bio-preservation strategy efficiently diminished microbial growth (S. aureus > E. coli O157:H7 > P. aeruginosa > S. enteritidis) and augmented the mayonnaise sample's shelf life (>40 days). …”
Get full text

DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells by Maria Cristina Grimaldi, Sara Bozzer, Dick J. Sjöström, Dick J. Sjöström, Linnea I. Andersson, Tom Eirik Mollnes, Tom Eirik Mollnes, Per H. Nilsson, Per H. Nilsson, Luca De Maso, Federico Riccardi, Michele Dal Bo, Daniele Sblattero, Paolo Macor

“…IntroductionThe functionalization of nanoparticles (NPs) with an antiCD19 targeting mechanism represents a promising approach for the selective delivery of drugs and nucleic acids into normal and tumor B cells. This strategy has the advantage of minimizing off-target effects by restricting gene delivery to the desired cell population. …”
Get full text

Development of Cross-Sector Collaboration Indicators for Accelerating the Reduction of Stunting in South Sulawesi, Indonesia by Balqis Balqis, Suci Rahmadani, Muh. Yusri Abadi, St. Rosmanely, Arif Anwar, Laksmi Trisasmita, Ni Made Viantika Sulianderi, Faizal Fahmi, Arsunan Arsin, Muh. Amri Arfandi, Nur Annisa Hamka, Amaliah Amriani. AS

“…Background: To reduce stunting, the government of Indonesia, which has the fifth-highest prevalence of stunting in toddlers, launched the National Strategy for the Acceleration of Stunting Prevention (StraNas Stunting). …”
Get full text

Enhanced Piezoelectric Properties of Poly(L‐lactide) Nanocomposite Microfiber Scaffolds Due to Polydopamine‐Coating of Barium Titanate Nanoparticles by Richard Schönlein, Xabier Larrañaga, Asier Panfilo, Yu Li, Aitor Larrañaga, Guoming Liu, Alejandro J. Müller, Robert Aguirresarobe, Jone M. Ugartemendia

“…This contribution presents, for the first time, a nanocomposite strategy to enhance the piezoelectric properties of PLLA, while maintaining cytocompatibility. …”
Get full text

O2-self-supplying and glutathione-depleting scaffold for synergistic cancer therapy by Jiajia Zeng, Chongxian He, Xinna Bai, Cijun Shuai, Hao Pan

“…In summary, introducing the Ti3C2 nanosystem loaded with nanozyme into PLLA scaffold is a promising strategy to develop bone scaffold with multimodal anti-tumor function.…”
Get full text

Immediate and residual effect of tobacco powder compost and of NPK on N2O emissions and on N use in a wheat/corn crop succession by Pâmela Oruoski, Celso Aita, Stefen Barbosa Pujol, Heitor Luís Santin Bazzo

“…Considering its residual effect is an important strategy to optimize its use and mitigate N2O emissions to the atmosphere.…”
Get full text

Wildfire indicators modeling for reserved forest of Vellore district (Tamil Nadu, India) by Yara EzAl Deen Sultan, Kanni Raj Arumugam Pillai, Archana Sharma

“…This study examines the parameters contributing to wildfires in the Vellore Reserve Forest This paper aims to develop GIS-based risk maps and models to enhance fire protection, fuel mitigation strategies, and land use decisions by improving wildfire risk recognition and prediction. …”
Get full text

Development and validation of a UV/visible spectrophotometric method for simultaneous assay of paracetamol and ibuprofen by Timothée Mavanga Mabaya, Jocelyn Mankulu Kakumba, Mannix Mayangi Makola, Adelard Mbenza Puati, Didi Mana Kialengila, Jean Mavar Tayey Mbay, Jérémie Mbinze Kindenge

“…Subsequently, individual solutions were prepared to obtain calibration and validation standards for the method validation, using the total error strategy and studying various validation criteria (specificity, precision, accuracy, linearity, robustness). …”
Get full text