Comparative CT with stress manoeuvres for diagnosing distal isolated tibiofibular syndesmotic injury in acute ankle sprain: a protocol for an accuracy- test prospective study by João Carlos Rodrigues, Mario Lenza, Laercio Alberto Rosemberg, Durval do Carmo Santos Barros, Mario Ferretti, Alexandre Leme Godoy Santos, Marcelo Pires Prado, José Felipe Marion Alloza, Renato Amaral Masagão, Adham do Amaral e Castro, Marco Kawamura Demange

“…This study aims to investigate which strategy among an existing CT index test and two new add-on CT index tests with stress manoeuvres more accurately diagnoses syndesmotic instability. …”
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Assimilating ESA CCI land surface temperature into the ORCHIDEE land surface model: insights from a multi-site study across Europe by L.-E. Olivera-Guerra, C. Ottlé, N. Raoult, P. Peylin

“…We use the land data assimilation system for the ORCHIDEE model (ORCHIDAS) to conduct a series of synthetic twin data assimilation experiments accounting for actual data availability and uncertainty from ESA CCI-LST to find an optimal strategy for assimilating LST. Here, we test different strategies of assimilation, notably investigating (i) two optimization methods (a random search technique and a gradient-based technique) and (ii) different ways to assimilate LST using the only raw data and/or different characteristics of the LST diurnal cycle (e.g. mean daily, daily amplitude, maximum and minimum temperatures, and morning and afternoon gradients). …”
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The role of ferroptosis in colorectal cancer and its potential synergy with immunotherapy by Wenhua Xia, Wenhua Xia, Yuanhao Lv, Yuanhao Lv, Yan Zou, Zhanting Kang, Zhaoyi Li, Jiaqi Tian, Hongyan Zhou, Wei Su, Wei Su, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong

“…In summary, ferroptosis offers a promising strategy to overcome CRC therapy resistance and enhance immunotherapy efficacy, warranting further investigation and translational application.…”
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Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model by Haoshu Fang, Chuanfeng Hua, Stefanie Weiss, Anding Liu, Wenhui Cheng, Ralf Claus, Jürgen Rödel, Olaf Dirsch, Uta Dahmen

“…Our results revealed that increasing innate immunity by G-CSF pretreatment and decreasing inflammatory responses using LBPK95A improved the survival rates in a rat sepsis model and could be a novel strategy to treat sepsis.…”
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Fluorine‐Induced Lattice Oxygen Participation in 2D Layered Double Hydroxide/MXene Hybrids for Efficient Oxygen Evolution by Chengang Pei, Min‐Cheol Kim, Unbeom Baeck, Won Tae Hong, Jong Hun Kim, Hyungu Han, Jaekyum Kim, Sung Min Cho, Xu Yu, Jongwook Park, Ho Seok Park, Jung Kyu Kim

“…This study presents a promising strategy to design highly active electrocatalysts for energy conversion and storage.…”
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The influence of walking accessibility on station-to-station passenger flow and its interaction with metropolitan race/class segregation: A case study of MARTA’s heavy-rail network... by Luis Enrique Ramos-Santiago, Luke Derochers

“…Mass transit is a key transport strategy in helping cities decarbonize, adapt to an era of rapid climate change, and guide rapid urbanization. …”
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A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance by Annie Sparrow, Meghan Smith-Torino, Samuel M. Shamamba, Bisimwa Chirakarhula, Maranatha A. Lwaboshi, Christine Stabell Benn, Konstantin Chumakov

“…The unique power of vaccines is reduced by vaccination-only strategy, and in fact breeds vaccine-derived polio. …”
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Effect of Biogas Slurry on the Nutrient Cycling and Micro-organisms Community in Two Types of Soil by Pengcheng Li, Dongqi Jiang, Shuqiang Wang, Xianying Zhang, Yulan Zhang, Yonghuan Wang, Zhenhua Chen, Nan Jiang

“…Utilizing BS as fertilizer is a viable strategy applicable for Northeastern China’s agriculture, and application dosages must be adjusted according to experimental results.…”
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Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells by Qimin Hai, Peter Bazeley, Juying Han, Gregory Brubaker, Jennifer Powers, Claudia M. Diaz-Montero, Jonathan D. Smith

“…<b>Methods</b>: We refined the traditional embryoid body-based differentiation strategy to create a novel three-phase method that optimizes yield, consistent quality, and reproducibility. …”
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Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response by Jing Wang, Jin Wang, Yi-Na Wang, Yuan-Yuan Wang, Wen-Juan Bai, Nai-Jun Miao

“…Our data reveal a previously unrecognized antitumor mechanism of VBL and suggest a drug repurposing strategy combining VBL with immune checkpoint inhibitors to improve malignant tumor immunotherapy.…”
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Exploring nutraceutical approaches linking metabolic syndrome and cognitive impairment by Rebecca Sonnino, Gea Ciccarelli, Simona Moffa, Laura Soldovieri, Gianfranco Di Giuseppe, Michela Brunetti, Francesca Cinti, Eleonora Di Piazza, Antonio Gasbarrini, Enrico C. Nista, Alfredo Pontecorvi, Andrea Giaccari, Teresa Mezza

“…Understanding their efficacy could provide practical tools to complement lifestyle changes, offering a more comprehensive strategy for managing metabolic-cognitive syndrome.…”
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Nanosurface‐Reconstructed Fuel Electrode by Selective Etching for Highly Efficient and Stable Solid Oxide Cells by Yueyue Sun, Jun Zhou, Jiaming Yang, Dragos Neagu, Zhengrong Liu, Chaofan Yin, Zixuan Xue, Zilin Zhou, Jiajia Cui, Kai Wu

“…This novel selective etching method in perovskite oxides provides an appealing strategy to fabricate hierarchical electrocatalysts for highly efficient and stable SOCs with broad implications for clean energy systems and CO2 utilization.…”
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AbaComplex Enhances Mitochondrial Biogenesis and Adipose Tissue Browning: Implications for Obesity and Glucose Regulation by Serena Sagliocchi, Elisabetta Schiano, Lucia Acampora, Fortuna Iannuzzo, Annunziata Gaetana Cicatiello, Caterina Miro, Annarita Nappi, Federica Restolfer, Mariano Stornaiuolo, Stefano Zarrilli, Fabrizia Guerra, Gian Carlo Tenore, Monica Dentice, Ettore Novellino

“…The browning of WAT, whereby white fat cells acquire characteristics of brown adipose tissue (BAT) with enhanced thermogenic capacity, represents a promising strategy to enhance metabolic health. In this study, we investigated the effects of chronic supplementation with an infusion based on lyophilized, thin nectarines rich in abscisic acid (ABA), named AbaComplex, on promoting browning of WAT and activating BAT in mice. …”
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Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…The hydrogel group exhibited a significant promotion in collagen content and reduction in HIF-1α, which effectively hastened tract maturation.Conclusion: Therefore, our study provides new and critical insights into a strategy to design bioactive hydrogels with multiple functions, which can open up a new avenue for accelerated wound healing after gastrostomy. …”
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Mindfulness Intervention for Health Information Avoidance in Older Adults: Mixed Methods Study by Chenyu Gu, Liquan Qian, Xiaojie Zhuo

“…Findings offer practical recommendations for improving digital health information delivery and health management strategies for older adults.…”
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Sputum Smear Positive Pulmonary Tuberculosis Diagnostic Dropout Rate in Public Health Facilities, Addis Ababa, Ethiopia by Daniel Melese Desalegn, Kumera Terfa Kitila, Boja Dufera Taddese, Tinsae Kidanemariam Hailu, Tariku Takle Dinku, Kassahun Demisse Asferie, Hanna Mekonnen Balcha, Chalachew Sisay Gebeyehu, Girmay Medhin

“…In this study smear positive pulmonary tuberculosis diagnostic dropout rate was high compared to WHO reported for the new strategy shift implying the importance of shifting to same-day approach. …”
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Changes of the ecological environment status in villages under the background of traditional village preservation: a case study in Enshi Tujia and Miao Autonomous Prefecture by Fu Li, Huiqiong Xia, Jie Miao, Jialin Yang

“…Abstract The preservation of Chinese traditional villages plays a crucial role in promoting the sustainable development of rural natural, cultural, and ecological environments. It is also a key strategy for achieving rural revitalization. Current research on traditional villages predominantly focuses on the realm of cultural landscapes, with an emphasis on preserving the cultural ecological value of these communities. …”
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Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems by Hasan Nikkhah, Zahir Aghayev, Amir Shahbazi, Vassilis M. Charitopoulos, Styliani Avraamidou, Burcu Beykal

“…Building on this foundation, we extend this strategy to solve a high-dimensional and highly constrained nonlinear crude oil refinery operation problem that has not been previously tackled in this context. …”
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Fault tolerant &amp; priority basis task offloading and scheduling model for IoT logistics by Asif Umer, Mushtaq Ali, Ali Daud, Lal Hussain, Amal Bukhari, Ali Imran Jehangiri

“…Successful offloaded tasks are allocated to suitable VMs in the cloud and fog nodes. The proposed strategy selects the most suitable VM for offloaded tasks using a multi-criteria decision-making process to reduce energy consumption, SLA violations, and execution costs. …”
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Intraoperative haemodynamic optimisation using the Hypotension Prediction Index and its impact on tissular perfusion: a protocol for a randomised controlled trial by Javier Ripollés-Melchor, Ane Abad-motos, Juan Victor Lorente, Ignacio Jimenez, Alejandra Becerra, Wilbert Wesselink, Francesca Reguant, Irene Mojarro, Maria de los Angeles Fuentes, Elizabeth Agudelo, Francisco Herrero-Machancoses, Paula Callejo, Joan Bosch, Manuel Ignacio Monge

“…This study aims to determine whether a treatment protocol based on the prevention of arterial hypotension using the HPI algorithm reduces the duration and severity of intraoperative hypotension compared with the recommended goal-directed fluid therapy strategy and may improve tissue oxygenation and organ perfusion.Methods and analysis We will conduct a multicentre, randomised, controlled trial (N=80) in high-risk surgical patients scheduled for elective major abdominal surgery. …”
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