Intermittent Fasting: Weighing the Benefits and Drawbacks for Health and Longevity – A Comprehensive Literature Review by Marta Wojtczak, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej, Alicja Kot, Natalia Myśliwiec, Adrian Różycki

“…By addressing these gaps, IF could evolve into a sustainable, evidence-based strategy for improving global health outcomes. …”
Get full text

Identifying the mentorship needs among faculty in a large department of psychiatry- support for the creation of a formal mentorship program by Mary Jane Esplen, Lisa M. Fiksenbaum, Elizabeth Lin, Shaheen A. Darani, John Teshima, Simone N. Vigod, Nicole Kozloff, Peter Szatmari, Krista L. Lanctôt, Certina Ho, Ivan Silver, Sophie Soklaridis, Jiahui Wong

“…Respondents supported a more formal, accessible, inclusive program, with training, tools, and a matching strategy based on mentee preferences. Conclusions Challenges and inequities were identified with the department’s current ad hoc approach to mentorship. …”
Get full text

Ebbs and Flows of Marine Biodiversity: Navigating Spatiotemporal Patterns of Environmental DNA in a Coastal Tidal Ecosystem by Michelle Scriver, Ulla vonAmmon, Xavier Pochon, Martin Zirngibl, Francois Audrezet, Kaeden Leonard, Kylie Pedersen, Nick Bamford, Ngairo Tahere, Jo‐Ann L. Stanton, Neil J. Gemmell, Anastasija Zaiko

“…Understanding eDNA dynamics in tidal areas is critical for guiding sampling strategy design and interpreting molecular detection results. …”
Get full text

Evaluation of Ecosystem Services and Tradeoff and Synergy in the Alpine and Canyon Region of Southwest China Based on Multi-source Geographic Data by LIU Jing, XIANG Jiayi, ZHANG Donghai, LAN Mengyao, GUAN Yinghui

“…[Objective] The alpine and canyon region of Southwest China is a crucial ecological security barrier within the national “Three Zones and Four Belts” strategy, and it plays an essential role in ensuring national ecological security and promoting regional high-quality development. …”
Get full text

Thermosensitive injectable in situ forming hydrogel incorporating anti-oxidative stress and anti-inflammatory nanoparticles for vital pulp therapy of pulpitis by Lixin Zhang, Xianling Ning, Jingyi Cui, Yanqiang Zhao, Fei Xie, Ningxin Zhu, Dan Wang, Man Qin, Zhiqiang Lin, Yuanyuan Wang

“…Overall, use of this PBNPs@PPP hydrogel has potential to be a new, safe and efficient strategy for vital pulp therapy to treat pulpitis.…”
Get full text

Single-staged Surgical Correction of Kyphotic Deformity due to Dorsal Spinal Tuberculosis in Pediatric Patients: Outcome Analysis by Mageswaran Shanmugavelu, Makesh Ram Sriraghavan, Prabhu Aloy, Poornima Kumararaja, Sai Vinay Bharadwaj Namala

“…The multifaceted goals of surgery in spinal TB underscore the importance of a thorough understanding of the disease and a collaborative approach, and it ensures a comprehensive strategy. Thus posterior surgical method is effective in accomplishing debridement, obtaining satisfactory clinical results, correcting kyphotic deformity, and maintaining the correction.…”
Get full text

Status survey of uncrossmatched type O suspended RBCs in patients with emergency transfusion by PENG Zhuoyue, XU Shilan, YANG Xinxin, CHEN Chunxia, TAN Bin

“…[Objective] To investigate the implementation of emergency transfusion strategy of uncrossmatched type O suspended RBCs based on the single-center clinical practice, which is "emergency transfusion is initiated by the authorized doctor of the emergency department, and no more than 4 U of type O uncrossmatched suspended RBCs are issued within 15 minutes in the transfusion department"(referred as the Practice), so as to provide reference for blood management. …”
Get full text

Carbon-carbon triple bond cleavage and reconstitution to achieve aryl amidation using nitrous acid esters by Zi-Ying Wang, Shoujun Wang, Nan-Nan Dai, Yao Xiao, Yu Zhou, Wen-Chan Tian, Dongru Sun, Qiang Li, Yong Wang, Wen-Ting Wei

“…Abstract C–C bond cleavage and recombination provide an efficient strategy for the modification and reconstruction of molecule structures. …”
Get full text

Oscillatory ventilation enhances oxygenation and reduces inflammation in an animal model of acute respiratory distress syndrome: an experimental study by Luiz Alberto Forgiarini Junior, Luiz Felipe Forgiarini, Arthur de Oliveira Paludo, Rodrigo Mariano, Mikael Marcelo de Moraes, Elaine Aparecida Felix, Cristiano Feijó Andrade

“…Conclusion: Variable ventilation with bi-oscillatory level of PEEP demonstrated a potential ventilatory strategy for lung protection in an experimental model of ARDS.…”
Get full text

Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes by Danmei Li, Shuai Li, Shukun He, Hongpu He, Guangxun Yuan, Binbin Ma, Yijun Zhang, Chengjie Yuan, Zhiqin Liu, Zhenhan Deng, Jian Xu

“…These results suggest its potential as a promising therapeutic strategy for tendon disorders.…”
Get full text

Understanding crystallinity indexes benchmarking concept from optimized parametric ionic liquid pretreatment using 1-ethyl-3-methylimidazolium Acetate [EMIM]Ac on oil palm biomass by Amizon Azizan, Rosmaria Abu Darim, Intan Suhada Azmi, Rafidah Jalil, Shareena Fairuz Abdul Manaf

“…The optimized pretreatment strategy indicated a moderate balance between ionic liquid concentration percentage and operating temperature on a solid loading per volume basis. …”
Get full text

Determinants of Halal Tourism of Setu Babakan Jakarta Based on Global Muslim Travel Index and Importance Performance Analysis by Tati Handayani, Sufyati HS, Purwanto Widodo, Pusporini, Anggi Angga Resti

“…These findings are expected to facilitate managers and local governments to develop the right strategy so that visitors to Setu Babakan increase by improving facilities that are lacking.   …”
Get full text

Improving polyketide biosynthesis by rescuing the translation of truncated mRNAs into functional polyketide synthase subunits by Yan Liu, Chaoyi Song, Qingwen Cui, Hongluan Sun, Chanjuan Jiang, Ruofei Guo, Ruoting He, Zhen Li, Ji Luan, Hailong Wang

“…The truncated mRNA translation rescue strategy will facilitate engineering of multi-domain proteins to enhance their functions.…”
Get full text

Efficacy of non-invasive ventilation and oxygen therapy on immunocompromised patients with acute hypoxaemic respiratory failure: protocol for a systematic review and meta-analysis... by Juhong Shi, Gang Liu, Meng Wang, Tao Wang, Yi Li, Yi Yang, Xuezhong Yu, Huadong Zhu, Yong Ma, Zongru Li, Lixi Zhang, Kun He, Jianqiang He

“…This meta-analysis aims to evaluate whether NIV or oxygen therapy is the more appropriate initial oxygenation strategy for the immunocompromised patients with acute respiratory failure.Method We will search all the RCTs that compared the efficacy of NIV and oxygen therapy on immunocompromised adult patients with acute hypoxaemic respiratory failure on the major databases (Cochrane Library, MEDLINE, EMBASE, Web of Science and others), conference proceedings and grey literature. …”
Get full text

Prioritizing Forestation in China Through Incorporating Biogeochemical and Local Biogeophysical Effects by Yu Li, Pengyi Zhang, Huanhuan Wang, Hui Ma, Jie Zhao, Mengyang Xu, Mengyu Wang, Chenhui Guo, Chao Yue

“…Abstract Forestation is a key strategy for climate mitigation in China through its biogeochemical (BGC) effect of ecosystem carbon sequestration. …”
Get full text

Effect of probiotics combined with immune checkpoint suppressors and chemotherapeutic agents on digestive system function, intestinal immunity and prognosis in patients with metast... by Xiaolei Wang, Yuxia Huang, Zhen Yang, Yang Yang, Fenfen Wei, Min Yan, Fanfan Li, Chenghao Wang

“…This combination therapeutic strategy can balance the imbalanced intestinal flora, improve intestinal function, and lessen the incidence of adverse events, so it is worthy of clinical application and can lessen the incidence of adverse reactions.…”
Get full text

A Lipiodol Pickering Emulsion Stabilized by Iron‐Doped Carbon Nanozymes for Liver Transarterial Chemoembolization by Xiancheng Xia, Yang Li, Rongkang Huang, Yuanbin Wang, Wenxuan Xiong, Hui Zhou, Min Li, Xidong Lin, Youchen Tang, Bo Zhang

“…Abstract Transarterial chemoembolization (TACE) utilizing a water‐in‐oil lipiodol emulsion is a preferable therapeutic strategy for advanced liver cancer in clinical practice. …”
Get full text

Integrating machine learning and structure-based approaches for repurposing potent tyrosine protein kinase Src inhibitors to treat inflammatory disorders by Muhammad Waleed Iqbal, Muhammad Shahab, Zakir ullah, Guojun Zheng, Irfan Anjum, Gamal A. Shazly, Atrsaw Asrat Mengistie, Xinxiao Sun, Qipeng Yuan

“…Due to the specificity and selectivity problems of previously discovered inhibitors like dasatinib and bosutinib, we employed an integrated machine learning and structure-based drug repurposing strategy to find novel, targeted, and non-toxic Src kinase inhibitors. …”
Get full text

Effect of a Nutritional Education Intervention on the Reduction of Added Sugar Consumption in Schoolchildren in Southeastern Mexico: Community Study by Carmen Morales-Ruán, Teresa Shamah-Levy, Danae Gabriela Valenzuela-Bravo, Rebeca Uribe-Carvajal, Corin Hernández-Palafox, María Concepción Medina-Zacarías, Ignacio Méndez Gómez-Humarán

“…Consumption of added sugars negatively affects schoolchildren’s health, making it essential to promote strategies designed to reduce their intake through educational interventions. …”
Get full text

MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…Targeting and inhibiting miRNA-21 in CD44+ cells could represent a promising novel strategy in OSCC treatment.…”
Get full text