Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis by E.A. Burylova, L.A. Mamaeva, A.S. Berdnikova, O.K. Fedorova

“…Multidisciplinary diagnostic and treatment approach to suspected sarcoidosis provides timely verified diagnosis and management strategy. This paper addresses case report of systemic sarcoidosis in a 34-year-old man. …”
Get full text

Enhancing mechanical properties of (HfMoNbZrTa)1-xNx films through multi-phase structures in substoichiometric compositions by Yiming Ruan, Jigang Xie, Lin He, Fugui Zhang, Jie Shi, Hengning Hu, Yun Chen, Rui Shu, Liuquan Yang, Hao Du

“…Elemental composition design is a common strategy for tuning the crystallographic structure of films, thereby optimizing their mechanical properties. …”
Get full text

Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint by Yan Wang, Xiaoye Jin, Rui Qiu, Bo Ma, Sheng Zhang, Xuyang Song, Jinxi He

“…Personalized cancer therapy has emerged as a promising strategy to enhance treatment effectiveness and precision. …”
Get full text

Enhancement of Fertilizer Efficiency Through Chinese Milk Vetch and Rice Straw Incorporation by Tahir Shah, Adnan Anwar Khan, Yahya Mohammed Ali Aljerib, Muhammad Tariq, Donghui Li, Mingjian Geng, Yajun Gao, Qiang Zhu

“…The above findings suggest that combining RS returning with CMV incorporation is a long-term sustainable strategy for maintaining soil health, and it could reduce fertilizer addition by 20% without prejudicing rice grain yield under a rice-green manure rotation system.…”
Get full text

Single-molecule manipulation of copper nanoclusters for modulating nonlinear optics by Xuekun Gong, Zhuang-Hua Liu, Qinghua Xu, Lin Wang, Qingxiang Guo, Jian Zhang, Qiao-Hong Li, Wei-Hui Fang, Hui Shen

“…This study highlights the potential of structurally precise copper nanoclusters as OL materials and advances the understanding of nanoparticulate material fabrication using a single-molecule strategy.…”
Get full text

Field Development Optimization for Low-Productivity Gas Wells under Intermittent Production by Wei Tian, Yi Liu, Xuri Li, Youliang Jia, Yixuan Wang, Li Li, Zhengyan Zhao, Weihong Ding, Wenxin Zhou, Wenyue Sun

“…Intermittent production, where wells are periodically shut-in and open, is a common approach to address these problems. This strategy allows formation pressure recovery during the shut-in period, which leads to a higher gas rate during the production period to carry liquids out of the wellbore. …”
Get full text

Measuring how healthcare organizations respond after patients experience harm: perspectives and next steps by Lauge Sokol-Hessner, Lauge Sokol-Hessner, John Adams, Carole Hemmelgarn, Beth Miller, Diane O'Connor, Melissa Parkerton, Leilani Schweitzer, J. Matthew Austin, J. Matthew Austin

“…Ongoing engagement and strategy will be essential to move CRP measurement forward.…”
Get full text

Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques. by Christopher T Edwards, Kirti A Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagne, Nadia Golden, Hadj Aoued, Kathryn L Pellegrini, Matthew R Burnett, Christopher Cole Honeycutt, Stacey A Lapp, Thang Ton, Mark C Lin, Amanda Metz, Andrei Bombin, Kelly Goff, Sarah E Scheuermann, Amelia Wilkes, Jennifer S Wood, Stephanie Ehnert, Stacey Weissman, Elizabeth H Curran, Melissa Roy, Evan Dessasau, Mirko Paiardini, Amit A Upadhyay, Ian N Moore, Nicholas J Maness, Daniel C Douek, Anne Piantadosi, Raiees Andrabi, Thomas R Rogers, Dennis R Burton, Steven E Bosinger

“…As the next step in the pre-clinical testing of S2-directed antibodies as a strategy to protect from SARS-CoV-2 infection, we evaluated the in vivo efficacy of CC40.8 in a clinically relevant non-human primate model by conducting passive antibody transfer to rhesus macaques (RM) followed by SARS-CoV-2 challenge. …”
Get full text

Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy by Tarek Kamal Abouzed, Seiichi Munesue, Ai Harashima, Yusuke Masuo, Yukio Kato, Khaled Khailo, Hiroshi Yamamoto, Yasuhiko Yamamoto

“…Treatment with salicylate and pyridoxamine could prevent the development of diabetic nephropathy in mice and, therefore, would be a potentially useful therapeutic strategy against kidney problems in patients with diabetes.…”
Get full text

In Vivo Evaluation of the Combined Anticancer Effects of Cisplatin and SAHA in Nonsmall Cell Lung Carcinoma Using [18F]FAHA and [18F]FDG PET/CT Imaging by Skye Hsin-Hsien Yeh, Ming Hsien Lin, I. I. Leo Garcia Flores, Uday Mukhopadhyay, Danial Young, Kazuma Ogawa, Jeong-Hwan Jeong, William Tong, Juri G. Gelovani, Nobuyoshi Fukumitsu

“…Combining standard drugs with low doses of histone deacetylase inhibitors (HDACIs) is a promising strategy to increase the efficacy of chemotherapy. …”
Get full text

Spermine driven water deficit tolerance in early growth phases of sweet corn genotypes under hydroponic cultivation by Tahoora Batool Zargar, Mawia Sobh, Oqba Basal, Tibor Janda, Magda Pál, Szilvia Veres

“…Abstract Sweet corn is highly susceptible to water deprivation, making it crucial to identify effective strategies for enhancing its tolerance to water deficit conditions. …”
Get full text

Marine Shale Gas Occurrence and Its Influencing Factors: A Case Study from the Wufeng-Longmaxi Formation, Northwestern Guizhou, China by Taotao Cao, Hu Liu, Anyang Pan, Mo Deng, Qinggu Cao, Ye Yu, Yanran Huang, Zhenghui Xiao

“…Shale gas occurrence, free gas/sorbed gas ratio, and their influencing factors are crucial for shale gas exploitation strategy. Results indicated that the Wufeng-Longmaxi shales are dominated by type I kerogen, with total organic carbon (TOC) and equivalent vitrinite reflectance (eqvRo) of 0.77%–6.98% and 2.37%–2.53%, respectively. …”
Get full text

Interpretation of COVID-19 Epidemiological Trends in Mexico Through Wastewater Surveillance Using Simple Machine Learning Algorithms for Rapid Decision-Making by Arnoldo Armenta-Castro, Orlando de la Rosa, Alberto Aguayo-Acosta, Mariel Araceli Oyervides-Muñoz, Antonio Flores-Tlacuahuac, Roberto Parra-Saldívar, Juan Eduardo Sosa-Hernández

“…Detection and quantification of disease-related biomarkers in wastewater samples, denominated Wastewater-based Surveillance (WBS), has proven a valuable strategy for studying the prevalence of infectious diseases within populations in a time- and resource-efficient manner, as wastewater samples are representative of all cases within the catchment area, whether they are clinically reported or not. …”
Get full text

Exploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis by Emily J. Tomas, Yudith Ramos Valdes, Jennifer Davis, Bart Kolendowski, Adrian Buensuceso, Gabriel E. DiMattia, Trevor G. Shepherd

“…Interestingly, our results suggest that specifically targeting aurora kinase A (AURKA) may represent a promising therapeutic strategy since our cells were equally sensitive to Alisertib treatment as both spheroids and organoids. …”
Get full text

The Impact of Creatine Supplementation on Physical Performance, Cognitive Functions, and Safety – A Literature Review by Adam Sobiński, Matylda Czerwonka, Zuzanna Kościuszko, Katarzyna Kurza, Silvia Ciraolo, Julianna Podolec, Agnieszka Kulczycka-Rowicka, Katarzyna Lesiczka-Fedoryj, Joanna Wojda, Anna Walczak

“…Conclusions: Creatine supplementation is a safe, effective strategy for enhancing physical performance, especially with resistance training. …”
Get full text

Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6 by Johannes Woelk, Florian Hornsteiner, Stephanie Aschauer-Wallner, Patrizia Stoitzner, Gottfried Baier, Natascha Hermann-Kleiter

“…The therapeutic targeting of NR2F6 may be a promising strategy for boosting NKp46-dependent NK-cell-mediated tumor surveillance and metastasis.…”
Get full text

A Multi-Year Study of Forchlorfenuron’s Effects on Physical Fruit Quality Parameters in <i>A. chinensis</i> var. <i>chinensis</i> by Giovanni Mian, Michele Consolini, Antonio Cellini, Andrea Strano, Tommaso Magoni, Marco Mastroleo, Irene Donati, Francesco Spinelli

“…Overall, CPPU can be a potential strategy to enhance fruit quality, but its effectiveness depends heavily on field management practices. …”
Get full text

pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG by Jing Wu, Shuang Li, Tete Li, Xinping Lv, Mingyou Zhang, Guoxia Zang, Chong Qi, Yong-Jun Liu, Liang Xu, Jingtao Chen

“…These results are relevant to the further study of the role and mechanism of pDC-induced antitumor effects and may aid in the development of a new strategy for future tumor immunotherapy.…”
Get full text

Influences of non-uniformly distributed forming loads on deformation sequence and texture evolution in tailor heat treated Al6014 blanks by Nan Xiang, Meng-han Yang, Wan-ting Sun, Tao Huang, Hai-rui Zhang, Peng-yi Wang, Fei-yang Cheng

“…In this study, to address these issues, a control strategy that utilizes non-uniformly distributed pressure (NUDP) to regulate the regional deformation behaviors of tailor heat treated blank (THTB) is proposed. …”
Get full text

Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…The effects of NX210c on claudin-5 and biomarkers influencing BBB integrity—and the overarching brain protection it offers—provide a novel therapeutic strategy targeting an underlying driver of neurodegenerative conditions for which disease-modifying treatments are limited or not available.…”
Get full text