Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica by Young-Kyoung Park, Lucie Studena, Piotr Hapeta, Ramdane Haddouche, David J. Bell, Pablo Torres-Montero, Jose Luis Martinez, Jean-Marc Nicaud, Adriana Botes, Rodrigo Ledesma-Amaro

“…Through the modulation of key enzyme expression, we successfully demonstrated an improvement in β-caryophyllene production. This strategy suggests its potential extension to studies involving the microbial production of various industrially relevant terpenes.…”
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Enhancing the photocatalytic performance and chemical durability of AZ31 magnesium alloy by incorporating two types of nanoparticles through plasma electrolytic oxidation by Mosab Kaseem, Abdullah H. Alluhayb, Talitha Tara Thanaa, Arash Fattah-alhosseini, Mohammad Alkaseem

“…This results in a photocatalytic efficiency of 89.54% within 2 h of exposure to visible light using the BA-W-Sn sample, which outperforms other samples. This integrated strategy enables the study to contribute significantly to expanding the practical applications of MgO-based materials. …”
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Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease by Yi Xue, Tao Wang, Ji-Peng Liu, Qi Chen, Xiao-Long Dai, Min Su, Yu-Hang Cheng, Cheng-Chao Chu, Yun-Qing Ren

“…Thus, for treating skin-related diseases, antioxidant therapy may be an important strategy to alleviate these symptoms. However, traditional drug therapies have limitations in treating these conditions, such as lack of lasting effect and insufficient skin permeability. …”
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Effect of Multiple Gene Copy Number of Bacterial Lipase to Increase Lipase Production in Pichia pastoris by Esti Puspitasari, Yepy Hardi Rustam, Andreas Adhi Satya, Antonius Suwanto, Aris Tri Wahyudi, Rika Indri Astuti

“…This research aims to increase extracellular T1.2RQ lipase secretion (free lipase) with multiple gene copy number strategies in Pichia pastoris and it was first performed on lipase from Geobacillus stearothermophilus T1.2. …”
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Guanosine enhances the bactericidal effect of ceftiofur sodium on Streptococcus suis by activating bacterial metabolism by Yue Dong, Xiaona Liu, Shanshan Xiong, Mingyu Cao, Haojie Wu, Long Chen, Mengmeng Zhao, Yadan Zheng, Zhiyun Zhang, Yanyan Liu, Yanhua Li, Qianwei Qu, Chunliu Dong

“…The combination of non-antibiotic compounds with antibiotics is considered a promising strategy against multidrug-resistant bacteria. However, the mechanism by which metabolites act as antibiotic adjuvant remains unclear. …”
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Restoring riparian habitats for benefits to biodiversity and human livelihoods: a systematic map protocol for riparian restoration approaches in the tropics by Sheena Davis, Matthew Grainger, Marion Pfeifer, Zarah Pattison, Philip Stephens, Roy Sanderson

“…Heterogeneity will likely be present in the data; therefore, studies will be grouped appropriately based on the restoration strategy implemented and, on the type of outcome measured. …”
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Genome-wide development of simple sequence repeat (SSR) markers at 2-Mb intervals in lotus (Nelumbo Adans.) by Fengluan Liu, Lin Xi, Naifeng Fu

“…This work reveals a novel and convenient strategy for developing highly polymorphic SSR markers at any location throughout the lotus genome, and it sheds light on the development of SSR molecular markers in other plant species.…”
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Continuity and volume of bone cement and anti osteoporosis treatment were guarantee of good clinical outcomes for percutaneous vertebroplasty: a multicenter study by Zhen Cheng, Guangzong Ren, Ziyi Li, Xianda Gao, Di Zhang, Guiyue Chen

“…The purpose of our study was to identified the associated factors for good clinical outcomes and provide evidence for surgical strategy. Material and methods 186 patients who underwent PVP from January 2021 to January 2023 were reviewed retrospectively in the study. …”
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Design and application of a pressure relief pad for preventing pressure injuries (一种防压力性损伤减压垫的设计与应用) by ZHANG Yitian (张怡天), SUN Xiumei (孙秀梅), LI Jingwen (李静文)

“…Prone position ventilation is a kind of ventilation strategy for severe patients, especially patients with acute respiratory distress syndrome. …”
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Effectiveness of case management interventions for frequent users of healthcare services: a scoping review by Catherine Hudon, Maud-Christine Chouinard, Isabelle Dufour, Mireille Lambert, Cynthia Krieg

“…This study aimed to examine the evidence of the effectiveness of CM interventions for frequent users of healthcare services.Design Scoping review.Data sources An electronic literature search was conducted using the MEDLINE, Scopus and CINAHL databases covering January 2004 to December 2015. A specific search strategy was developed for each database using keywords ‘case management’ and ‘frequent use’.Eligibility criteria for selecting studies To be included in the review, studies had to report effects of a CM intervention on healthcare use and cost or patient outcomes. …”
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Outcomes of a pilot randomized clinical trial testing brief interventions to increase HIV pre-exposure prophylaxis uptake among rural people who inject drugs attending syringe serv... by Hilary L. Surratt, Sarah Brown, Abby L. Burton, Will Cranford, Laura C. Fanucchi, Christie Green, Stephanie M. Mersch, Rebecca Rains, Philip M. Westgate

“…Expanding access to pre-exposure prophylaxis (PrEP) has been endorsed as a key HIV prevention strategy; however, uptake among people who inject drugs (PWID) has been negligible in rural areas. …”
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PENERAPAN PENDEKATAN STUDENT CENTERED LEARNING (SCL) UNTUK MENINGKATKAN KETERAMPILAN BERPIKIR KREATIF DAN KOMUNIKATIF MAHASISWA PENDIDIKAN FISIKA SEMESTER III UNIVERSITAS BENGKULU by Rosane Medriati, Eko Risdianto

“…ABSTRAK   Penelitian ini bertujuan untuk medeskripsikan peningkatan keterampilan berpikir kreatif dan keterampilan komunikasi setelah diterapkan pendekatan student centered learning pada matakuliah Strategi Pembelajan Fisika. Penelitian ini menggunakan pendekatan statistik deskriptif. …”
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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…Our findings highlight the possible role of the IL-33/sST2 axis in the progression of AIH, opening a new door for developing a novel therapeutic strategy for AIH.…”
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The epidemiology of Hepatitis B, C and D in Germany: A scoping review. by Gyde Steffen, Ida Sperle, Siv Aina Leendertz, Navina Sarma, Sandra Beermann, Roma Thamm, Viviane Bremer, Ruth Zimmermann, Sandra Dudareva

“…To meet the world Health Organization (WHO) viral hepatitis (VH) elimination goals, a national strategy was developed by the German government in 2016. …”
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Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy by Yanjiao Li, Yanjiao Li, Jinyu Zhu, Congyang Yue, Siyuan Song, Limin Tian, Yi Wang, Yi Wang, Yi Wang

“…Overall, the ability to convert α-cells into β-cells represents a transformative strategy for diabetes treatment, offering hope for more effective and sustainable therapies for patients with severe β-cell loss.…”
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Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma by Ruilan Ma, Dian Yang, Peng Wang, Ziyi Zhang, Xuehong Zhang, Jialiang Song, Han Liu, Shuyan Liu, Yingqiu Zhang, Lijuan Zou

“…Hence, our study unravels a novel aspect of RIT1 mutations in lung cancer and suggests ferroptosis induction as a potential therapeutic strategy to treat lung cancer patients carrying RIT1 mutations.…”
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Sexual and reproductive health and rights, HIV and migration in southern Africa: A rapid review by G Musuka, I Chingombe, E Moyo, T Chikava, B Moyo, M Mapingure, H Musuka, T Dzinamarira

“…Utilising a population-concept-context framework, the review focuses on understanding the scope, nature and extent of interventions, identifying lessons learnt, and assessing existing policies and strategies. A comprehensive search strategy and screening process resulted in 19 studies and reports for inclusion. …”
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Effectiveness of community-based first aid training on head injury outcomes by Akilbekov Dzhumatovich, Mohamad Sorani

“…In conclusion, CBFA training is an effective strategy for improving head injury outcomes, particularly in disaster-prone and underserved regions. …”
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Prevalence and Associated Risk Factors of Childhood Obesity and Overweight in Erbil City, Kurdistan, Iraq: A Household Survey by Sabah Shareef Mohammed, Sherzad Abdulahad Shabu

“…This study was a household survey based on a cross-sectional study that was conducted, and a multi-stage sampling strategy was used to choose the study sample. A questionnaire was conducted to collect the data, SPSS was used for analysing the data, and Chi-square (X²), was used to identify any kind of association between different variables in the study, whereas the p-value was considered (0.05). …”
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Nanodrug‐Engineered Exosomes Achieve a Jointly Dual‐Pathway Inhibition on Cuproptosis by Hanxiao Sun, Yang Zou, Zhengtai Chen, Yan He, Kai Ye, Huan Liu, Lihong Qiu, Yufan Zhang, Yuexue Mai, Xinghong Chen, Zhengwei Mao, Wei Wang, Chenggang Yi

“…The local and controlled release of EXOsiFDX1‐PDA@CQ ensures the retention of the therapeutic agent at wound beds, effectively promoting wound healing. The strategy of engineered exosomes with functional nanoparticles (NPs) proposed in this study offers an efficient and scalable new approach for regulating cuproptosis.…”
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