Nonlinear Structural Fusion for Multiplex Network by Nianwen Ning, Feiyu Long, Chunchun Wang, Youjie Zhang, Yilin Yang, Bin Wu

“…Then, we construct a node similarity network based on embedding matrices and K-D tree algorithm. (2) In NSF, we present a nonlinear enhanced iterative fusion (EIF) strategy. EIF can strengthen high-weight edges presented in one (i.e., complementary information) or more (i.e., shared information) networks and weaken low-weight edges (i.e., redundant information). …”
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In vivo imaging and pharmacokinetics of percutaneously injected ultrasound and X-ray imageable thermosensitive hydrogel loaded with doxorubicin versus free drug in swine. by Jose F Delgado, Ayele H Negussie, Nicole A Varble, Andrew S Mikhail, Antonio Arrichiello, Tabea Borde, Laetitia Saccenti, Ivane Bakhutashvili, Joshua W Owen, Robert Morhard, John W Karanian, William F Pritchard, Bradford J Wood

“…Overall, the use of POL formulation offers a promising strategy for precise and localized drug delivery, that may minimize adverse effects. …”
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The impact of primary health care on AIDS incidence and mortality: A cohort study of 3.4 million Brazilians. by Priscila F P S Pinto, James Macinko, Andréa F Silva, Iracema Lua, Gabriela Jesus, Laio Magno, Carlos A S Teles Santos, Maria Yury Ichihara, Mauricio L Barreto, Corrina Moucheraud, Luis E Souza, Inês Dourado, Davide Rasella

“…This study evaluated the impact of the exposure to one of the largest community-based PHC programs in the world, the Brazilian Family Health Strategy (FHS), on AIDS incidence and mortality.<h4>Methods and findings</h4>A retrospective cohort study carried out in Brazil from January 1, 2007 to December 31, 2015. …”
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Clinical Outcome of Third-Line Pazopanib in a Patient with Metastatic Renal Cell Carcinoma by Michela Roberto, Maria Bassanelli, Elsa Iannicelli, Silvana Giacinti, Chiara D’Antonio, Anna Maria Aschelter, Paolo Marchetti

“…In a context characterized by different emerging options, with no general consensus on the optimal treatment strategy, the use of pazopanib in pretreated patients could be a suitable choice.…”
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Simultaneous Determination of 5 Components in the Leaves of Dimocarpus longan by Quantitative Analysis of Multicomponents by Single Marker (QAMS) Based on UPLC and HPLC by Jiani Mai, Jie Liang, XianFu Liu, LiuPing Tan, Hui Xu, YaoHua Li, YuShan Zhou, ChuanChuan Yang, ChenXi Xin

“…In this paper, a new strategy of quantitative analysis of multicomponents by a single marker (QAMS) method was first established to synchronously determine 5 components (ethyl gallate (C1), astragalin (C2), quercetin (C3), luteolin (C4), and kaempferol (C5)) in Dimocarpus longan by ultra-performance liquid chromatography (UPLC) and high-performance liquid chromatography (HPLC). …”
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The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion by Jing Yang, Zhunan Li, Aicong Li, Yayi Liu, Xinyan Zhang, Yong Zhang, Yuanpeng Gao

“…This suggests that targeting bCoronin-1A as a key factor influencing mycobacterial survival may be an effective breeding strategy to develop tuberculosis-resistant dairy cows.…”
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Variants of the Sliding Mode Control in Presence of External Disturbance for Quadrotor by Irfan Ahmad, Muwaida Liaquat, Fahad Mumtaz Malik, Hameed Ullah, Usman Ali

“…Control strategies have been implemented on quadrotor which is 6 Degree of Freedom (DOF) underactuated model and it is derived via Newton-Euler(NE) equations. …”
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Development and validation of a prediction model for chronic post-surgical pain risk: a single-center prospective study of video-assisted thoracoscopic lung cancer surgery by Xiong-Fei Zhang, Chang-Guo Peng, Hua-Jing Guo, Zhi-Ming Zhang

“…And the DCA curve showed that using our model to guide decisions resulted in a higher net benefit compared to a strategy of not screening or treating all patients. …”
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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

“…Our findings reveal a novel mechanism of action of HDAC1-3 inhibitors in MDSCs and suggest a potential synergistic immunotherapy strategy for clinical benefit in HCC.…”
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Postharvest wounding treatment influences flavone production and biological activities of the hairy root cultures of Scutellaria baicalensis by Hyeon Ji Yeo, Su Young Shin, Sang Un Park, Chang Ha Park

“…Conclusions Our results indicate that postharvest wounding treatment is a good strategy to increase flavone production and enhance the antibacterial activity of S. baicalensis hairy root cultures. …”
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In Vitro Studies of Bacterial Cellulose and Magnetic Nanoparticles Smart Nanocomposites for Efficient Chronic Wounds Healing by Bianca Galateanu, Mihaela-Cristina Bunea, Paul Stanescu, Eugenia Vasile, Angela Casarica, Horia Iovu, Anca Hermenean, Catalin Zaharia, Marieta Costache

“…The quality of life of patients with chronic wounds can be extremely poor and, therefore, over the past decades, great efforts have been made to develop efficient strategies to improve the healing process and the social impact associated with these conditions. …”
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Combined Use of Excimer Laser and High-Speed Rotational Atherectomy to Overcome a Severely Calcified Lesion in Endovascular Therapy by Keisuke Nakabayashi, Shinya Hata, Nobuhito Kaneko, Akihiro Matsui, Kazuhiko Tanaka, Hiroshi Ando, Minoru Shimizu

“…Therefore, we have to refrain from frequent use of this strategy; however, this method provides an option for severely calcified lesions.…”
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Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation by Xuan Deng, Lu Chang, Lingyu Tang, Haoqin Jiang, Xiao Xu, Xinju Zhang, Jian Chen, Liu Dong, Qianqian Xu, Ruoshui Cao, Jianbin Xiang, Ming Guan

“…As the most abundant antioxidant, glutathione (GSH) enables cancer cell survival and chemoresistance, by scavenging excessive reactive oxygen species (ROS) induced by platinum. Therapeutic strategy targeting GSH synthesis has been developed, however, failed to produce desirable effects in preventing cancer progression. …”
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Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in rats by Essia Hamdi, Slah Hidouri, Ana-Belén Muniz-Gonzalez, Marwa Kechnebbou, Salem Amara

“…Ascorbic acid grafted to silica nanoparticles (SiO2-NPs@AA) was used as a therapeutic strategy aimed to reduce ROS levels and enhancing antioxidant defenses. …”
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Therapy of Prostate Cancer by Nanoyam Polysaccharide by Cheng Peng, Bo Han, Baishan Wang, Gaoyang Zhao, Fang Yuan, Yeyu Zhao, Liang Liang, Dingge Liu, Zhaohui Zhai, Yanping Shen

“…Our results suggested that nanoyam polysaccharide strongly suppressed the growth of prostatic cancer by inducing the overexpression of caspase-3 and may be a potent anticancer strategy.…”
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Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

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Expression and prognosis of cellular senescence genes in head and neck squamous cell carcinoma by Chen Feng, Lijuan Zhu, Wei Mao, Pin Dong, Xinwei Chen

“…In recent years, numerous studies have shown that inducing tumor cells to enter a senescent state has become a feasible tumor control strategy. At present, cellular senescence has become a research hotspot in tumor prevention and treatment, as well as in cell biology. …”
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A scoping review on the psychosocial interventions used in day care service for people living with dementia. by Dympna Tuohy, Liz Kingston, Eileen Carey, Margaret Graham, Liz Dore, Owen Doody

“…<h4>Methods</h4>Inclusion/Exclusion criteria were identified and guided the search strategy. Participants were people aged 60 years and over living with dementia attending day care services. …”
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Effects of culturally-appropriate group education for migrants with type 2 diabetes in primary healthcare: pre-test-post-test design by Katarina Hjelm, Emina Hadziabdic

“…Furthermore, it is recommended for daily practice in primary healthcare, supporting healthcare professionals with a proven strategy to increase knowledge.…”
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Building a practice-based research network for healthcare integration: a protocol paper for a mixed-method project by Danielle Mazza, Sanne Peters, Grant Russell, Christopher Barton, Elizabeth Ann Sturgiss, Samantha Paubrey Chakraborty, Timothy Staunton-Smith, Maria De Leon - Santiago

“…Our iterative approach will be informed by a programme logic model and consists of: preparation work (pre-implementation assessment, literature review, community and stakeholder engagement), adaptation and building for a sustainable collaboration (strategy for recruitment and sustainment of members) and planning for network action (designing and implementing priority initiatives, monitoring and follow-up).Ethics and dissemination This project was approved by the Monash Health ethics committee (ERM Reference Number: 76281; Monash Health Ref: RES-21-0000-392L) and the Monash University Human Research ethics committee (Reference Number: 29786). …”
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