Treatment of early stage Supraglottic squamous cell carcinoma: meta-analysis comparing primary surgery versus primary radiotherapy by Krupal B. Patel, Anthony C. Nichols, Kevin Fung, John Yoo, S. Danielle MacNeil

“…Thus, a definite treatment strategy for early stage supraglottic SCC remains undefined. …”
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Correlation between low testosterone levels and the risk of osteoarthritis: a cross-sectional analysis of NHANES data (2011–2016) by Ning Ma, Fang Gao

“…The observed non-linear relationship suggests that maintaining optimal testosterone levels may be important for joint health, and testosterone replacement therapy could be explored as a preventative strategy for individuals with testosterone deficiency.…”
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Colonic Gastrointestinal Stromal Tumor: A Population-Based Analysis of Incidence and Survival by Zhiqiang Liu, Yan Sun, Yongfeng Li, Jingyuan Zhao, Shihong Wu, Zibo Meng, Heshui Wu

“…Therefore, a population-based analysis was useful to guide the clinical treatment strategy. Methods. The patients were selected from 2000 to 2015 based on Surveillance, Epidemiology, and End Results (SEER) database. …”
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Universal, untargeted detection of bacteria in tissues using metabolomics workflows by Wei Chen, Min Qiu, Petra Paizs, Miriam Sadowski, Toma Ramonaite, Lieby Zborovsky, Raquel Mejias-Luque, Klaus-Peter Janßen, James Kinross, Robert D. Goldin, Monica Rebec, Manuel Liebeke, Zoltan Takats, James S. McKenzie, Nicole Strittmatter

“…Here, we describe a biomarker-based strategy that utilises bacterial small molecular metabolites and lipids for direct detection of bacteria in complex samples using mass spectrometry (MS). …”
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Prospectiva del desarrollo local. Caso: Sistema de Riego El Cenizo, Estado Trujillo, Venezuela by Ligia Nathalie García Lobo

“…The organizational structure, resources for (R & D) staff are responsible for the process, methods for product`s development and organizational strategy as a differentiating factor, are the key success factors in the (R & D) of new SME products in Táchira.…”
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Non-pharmacological interventions for the prevention of type 2 diabetes in low-income and middle-income countries: a systematic review of randomised controlled trials by K M Saif-Ur-Rahman, Md Shariful Islam, Anupam Sarker, Rina Das, Saraban Ether

“…No meta-analysis was performed due to the lack of homogenous intervention strategies and study settings.Result A total of five studies were included for the review with a combined population of 1734 from three countries. …”
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Protocol for a systematic review on tertiary prevention interventions for patients with stroke in African countries by Adamu Addissie, Eva Johanna Kantelhardt, Thomas Frese, Eric Sven Kroeber, Lucas Adam, Alexander Bauer, Susanne Unverzagt

“…We will search from inception of each database and repeat this strategy 3 months prior to review submission. Details of all eligible studies will be extracted and risk of bias for outcomes on global disability or dependence in daily living will be assessed. …”
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Protective and risk factors of mental health of working age adults with adventitious total bilateral blindness and low vision: A scoping review protocol. by Nneoma Dike, Lucia D'Ambruoso, Heather May Morgan, Zoë Skea, Emma-Louise Tarburn

“…A three-step search strategy will be employed. Searches will be carried out in the following databases: Medline, Embase, PsycInfo, PsycArticles, CINAHL and Web of Science. …”
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Use of Coffee Silverskin and Stevia to Improve the Formulation of Biscuits by Garcia-Serna Esther, Martinez-Saez Nuria, Mesias Marta, Morales Francisco J., Castillo M. Dolores del

“…Decreasing the amount of sugar added to biscuits is a good strategy to obtain a healthy product. However, a reduction in the quantity of sugar may affect its nutritional value and quality. …”
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Facile synthesis of nanoporous Mg crystalline structure by organic solvent-based reduction for solid-state hydrogen storage by Hyesun Kim, HyeonJi Kim, Wonsik Kim, Choah Kwon, Si-Won Jin, Taejun Ha, Jae-Hyeok Shim, Soohyung Park, Aqil Jamal, Sangtae Kim, Eun Seon Cho

“…It is expected that the synthetic strategy conceived in this study can be further implemented to prepare different kinds of reactive porous metals in a facile and scalable way for the development of large-scale and distributed hydrogen storage systems for the emerging low-carbon hydrogen economy.…”
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Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia by Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida

“…Therefore, new strategies to enhance the effect of venetoclax are highly sought. …”
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Dietary Variations in a Multiethnic Parkinson’s Disease Cohort and Possible Influences on Nonmotor Aspects: A Cross-Sectional Multicentre Study by Anna Sauerbier, Anette Schrag, Pablo Martinez-Martin, Lynsey J. Hall, Miriam Parry, Laurie K. Mischley, Panagiotis Zis, K. Ray Chaudhuri

“…These data support the importance of considering ethnic diversity as part of recruitment strategy in nutrition and clinical studies.…”
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Venereal Diseases Treatment for Merauke’s Marind (Marind-Anim) Tribe in the Dutch Colonial Period by Rosmaida Sinaga, Hafnita Sari Dewi Lubis, Yushar Tanjung, Lister Eva Simangunsong

“…The government built hospitals and clinics and invented doctors who specialize in venereal disease to treat the patients. These strategies has succeeded in treating and eradicating venereal diseases among the Marind Tribe.…”
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Factors Influencing Behavioral Intention to Apply Freemium Services in Islamic Lifestyle Digital Applications Using Unified Theory of Acceptance and Use of Technology (UTAUT) by Yan Putra Timur, Ririn Tri Ratnasari, Anwar Allah Pitchay, Dyah Permata Sari, Muhammad Rifqi

“…To ensure sustainable revenue for ILDA developers, freemium strategy needs to be implemented. However, there is a lack of research examining the factors that influence the adoption of freemium strategies in ILDA products. …”
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Effectiveness and Safety of Using Standardized Treatment Protocols for Hypertension Compared to Usual Care: A Meta‐Analysis of Randomized Clinical Trials by Gautam Satheesh, Rupasvi Dhurjati, Vivekanand Jha, Aletta E. Schutte, Bolanle Banigbe, Dorairaj Prabhakaran, Andrew E. Moran, Abdul Salam

“…STPs can, therefore, be an efficient strategy to implement evidence‐based treatments and upscale treatment coverage, given the large untreated and uncontrolled hypertension burdens globally.…”
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Tailoring pyridine bridged chalcogen-concave molecules for defects passivation enables efficient and stable perovskite solar cells by Muhammad Azam, Yao Ma, Boxue Zhang, Xiangfeng Shao, Zhongquan Wan, Huaibiao Zeng, Haomiao Yin, Junsheng Luo, Chunyang Jia

“…Our work provides insight into the bowl-shaped Lewis base in defects passivation by coordinated strategy for high-performance photovoltaic devices.…”
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IL-1β and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype by Yongkang Wu, Bei Cai, Junlong Zhang, Beilei Shen, Zhuochun Huang, Chunyu Tan, Carla C. Baan, Lanlan Wang

“…Both IL-1β and IL-6 are highly expressed cytokines in RF+IgE+ SLE subtype which may be related to the pathogenesis of this special SLE subtype and provide accurate treatment strategy by neutralizing IL-1β and IL-6.…”
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Marine actinobacteria metabolites: unlocking new treatments for acne vulgaris by María Clara De La Hoz-Romo, María Clara De La Hoz-Romo, Luis Díaz, Luis Díaz, Javier Gómez-León, Marynes Quintero, Luisa Villamil

“…These findings highlight the therapeutic potential of marine actinobacteria in underexplored environments as a promising strategy for treating acne vulgaris, a chronic inflammatory skin condition.…”
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Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13 by Kun-Chi Wu, Hui-I Yang, Yu-Hsun Chang, Raymond Yuh-Shyan Chiang, Dah-Ching Ding

“…Therefore, miR-7704-overexpressed EVs derived from HUCMSCs showed potential as an innovative therapeutic strategy for treating OA. Further investigations should focus on optimizing dosage, understanding mechanisms, ensuring safety and efficacy, developing advanced delivery systems, and conducting early-phase clinical trials to establish the therapeutic potential of HUCMSC-derived EVs for OA management.…”
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Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK-Targeting Drugs in Psor... by Martina Morelli, Claudia Scarponi, Laura Mercurio, Francesco Facchiano, Sabatino Pallotta, Stefania Madonna, Giampiero Girolomoni, Cristina Albanesi

“…Thus, JAK targeting appears to be a reasonable strategy to treat psoriasis. Tofacitinib is an inhibitor of JAK proteins, which, similarly to SOCS, impedes JAK phosphorylation. …”
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