Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review by Mohammad Aidiel, Maisarah Abdul Mutalib, Rajesh Ramasamy, Nik Nasihah Nik Ramli, Shirley Gee Hoon Tang, Siti Hajar Adam

“…Together, the analysis provides a useful strategy for the structure–activity relationship (SAR) of flavonoid analogs in distinct protein markers, suggesting optimal functional group positioning to achieve balanced lipophilicity, effective hydrogen bonding, and simultaneously minimized steric hindrance in targeting specific cancer cell types.…”
Get full text

Lane Changing Control of Autonomous Vehicle With Integrated Trajectory Planning Based on Stackelberg Game by Dongmei Wu, Zhen Li, Changqing Du, Changsheng Liu, Yang Li, Xin Xu

“…Secondly, the cooperative game theory model is employed to design an adaptive weight adjustment strategy for the trajectory tracking controller. The weight coefficients for vehicle stability and path tracking accuracy are dynamically adjusted within the model predictive control method to adapt to the vehicle’s stability state. …”
Get full text

Des vestiges liés à la phase de construction de l’aqueduc de la Brévenne à Limonest (Métropole de Lyon) ? by Stéphane Ardouin, Cécile André-Chaze

“…The dating of ceramics and of a complete tegula discovered at Limonest corroborates the likelihood that they were dug prior to or contemporary with the construction of the aqueduct.The similarity of these ditches, their repetition at regular intervals and their location on several sections of the aqueduct route suggest a global strategy relating to the construction of the aqueduct rather than to occasional repairs. …”
Get full text

Déjouer le spectacle de la violence. Représenter les événements du 11 septembre 2001 by Bertrand GERVAIS

“…Michal Kosakowski gives a complementary strategy of this erasure in his film Just Like the Movies. …”
Get full text

DisCo P-ad: Distance-Correlation-Based <i><b>p</b></i>-Value Adjustment Enhances Multiple Testing Corrections for Metabolomics by Debmalya Nandy, Debashis Ghosh, Katerina Kechris

“…Methods: One such multiple testing correction strategy is to estimate the number of statistically independent tests, called the <i>effective number of tests</i>, based on the eigen-analysis of the correlation matrix between the features. …”
Get full text

Everyday life and boredom of people living with dementia in residential long-term care: a merged methods study by Doris Gebhard, Julia I. Frank

“…Person-centred dementia care provides a valuable intervention strategy to meet this requirement. Clinical trial number Not applicable.…”
Get full text

EDUCATIONAL TRAINING SIMULATOR FOR MONITORING READING TECHNIQUE AND SPEED BASED ON SPEECH-TO-TEXT (STT) METHODS by Olesia Barkovska, Heorhii Ivashchenko, Dmytro Rosinskiy, Daniil Zakharov

“…The practical significance lies in the fact that the use of information and communication technologies and gamification of the learning process motivates to gain knowledge and encourages learning not only due to the game strategy, but also due to the fact that the child receives approval and the opportunity to perform the task again so to improve skills. …”
Get full text

Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor by Maria Choleva, Smaragdi Antonopoulou, Elizabeth Fragopoulou

“…In the future, additional long-term randomized controlled trials or postprandial studies are needed to draw definitive conclusions and establish a viable cardioprotective strategy that incorporates the sustainable use of winery by-products.…”
Get full text

Time Series Classification of Raw Voice Waveforms for Parkinson&#x0027;s Disease Detection Using Generative Adversarial Network-Driven Data Augmentation by Marta Rey-Paredes, Carlos J. Perez, Alfonso Mateos-Caballero

“…This work intends to address an existing research gap by introducing a novel strategy that analyzes raw voice waveforms. Despite recent advancements, one of the significant hurdles is still the lack of extensive and diverse datasets. …”
Get full text

High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance by Masanori Nakata, Boyang Zhang, Yifei Yang, Takashi Okada, Norihito Shintani, Hitoshi Hashimoto, Toshihiko Yada

“…Antagonism of VPAC1-R may prevent progression of HFD-induced insulin resistance in the liver, providing a novel antidiabetic strategy.…”
Get full text

Flexibility in PAM recognition expands DNA targeting in xCas9 by Kazi A Hossain, Lukasz Nierzwicki, Modesto Orozco, Jacek Czub, Giulia Palermo

“…This dual functionality highlights how xCas9 broadens PAM recognition and underscores the importance of fine-tuning the flexibility of the PAM-interacting cleft as a key strategy for expanding the DNA targeting potential of CRISPR-Cas systems. …”
Get full text

Financial security as a factor of military security by O. P. Getmanets, D. V. Korobtsova

“…Based on the analysis of the Economic Security Strategy of Ukraine, it has been found that the state of the country’s financial security is assessed as unsatisfactory. …”
Get full text

Development of Korean Teaching Model for Surgical Procedures in Trauma -Essential Surgical Procedures in Trauma Course- by Hohyun Kim, Chan-Yong Park, Hyun-Min Cho, Kwang-Hee Yeo, Jae Hun Kim, Byungchul Yu, Seung-Je Go, Oh Sang Kwon

“…The ESPIT course may be an effective strategy for teaching surgical procedures, thus promoting better management of traumatic injuries.…”
Get full text

Assessing Microbial Diversity in Páramo Soils (Multistrategy Analysis): Effects of Potato Farming and Livestock Grazing in Nevados National Natural Park, Colombia by Lizeth Manuela Avellaneda-Torres, Tomás León Sicard, Edlin Guerra Castro, Esperanza Torres-Rojas

“…Four of the six evaluated matrices (physicochemical, enzymatic activities, most probable number, and arable functional groups) revealed significant differences according to land use. The strategy adopted by the arable functional group matrix, in which the diversity of nitrogen fixation, phosphate solubilization, and cellulolytic compounds was evaluated, showed the most significant impacts of the different factors (land use, season, and elevation), especially those caused by potato cultivation and livestock. …”
Get full text

Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81 by Meiyue Wang, Zejie Wu, Xiaoyu Zheng, Yishu Huang, Yizhou Jin, Jiaxin Song, Wanzhen Lei, Hua Liu, Riyue Yu, Haoqing Yang, Runtao Gao

“…Abstract Background The cartilage tissue regeneration mediated with mesenchymal stem cells (MSCs) is considered as a viable strategy for temporomandibular joint osteoarthritis (TMJOA). …”
Get full text

Cell-membrane targeting sonodynamic therapy combination with FSP1 inhibition for ferroptosis-boosted immunotherapy by Jian Chen, Qiyu Zhan, Lie Li, Simin Xi, Longmei Cai, Ruiyuan Liu, Lujia Chen

“…This work represents a promising tumor therapeutic strategy combining cell membrane targeting SDT and FSP1 inhibition, potentially inspiring further research in developing logical and effective cancer therapies based on synergistic SDT/ferroptosis.…”
Get full text

Polymeric nanoreactors for catalytic applications by Abou-Fayssal, Chantal Joseph, Poli, Rinaldo, Philippot, Karine, Riisager, Anders, Manoury, Eric

“…Anchoring the catalyst inside the polymer core protects it from the surrounding environment. This strategy also provides an efficient way to separate the catalyst from the products, thus permitting its recovery and recycling. …”
Get full text

Inheritance of scald resistance in four barley landraces by G. S. Konovalova, E. E. Radchenko

“…Therefore, the most rational plant breeding strategy should envisage broadening of genetic diversity of cultivated varieties. …”
Get full text

Can the African weaver ant be used as a vector of entomopathogenic fungi to bolster the biological control of tephritid fruit fly pests? by Thibault Nève de Mévergnies, Samba Diop, Massamba Diakhaté, Claire Detrain, Frédéric Bouvery, Thierry Brévault, Anaïs Chailleux

“…Entomovectoring is an environmentally friendly pest control strategy where insects act as precision vectors of a biocide to target pest populations through phoretic dispersal. …”
Get full text

Improving the Competitiveness of the Leading Universities of the North Caucasus Federal District in Sync with the Objectives of Regional Development by D. V. Petrosyants, V. V. Zubenko, P. S. Seleznev, I. V. Arzhanova

“…The purpose of the work is an analysis of the current state of the universities of the North Caucasus Federal District from the point of view of creating competitive regional development centers, bearing in mind the Spatial Development Strategy of Russia.The research methodology is based on empirical research methods (observation, comparison, data collection and study), current and prospective analysis and synthesis of theoretical and practical material, multivariate systems analysis, sociology, statistical analysis, etc.Results. …”
Get full text