Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway by Ryosuke Isotani, Masaki Igarashi, Masaomi Miura, Kyoko Naruse, Satoshi Kuranami, Manami Katoh, Seitaro Nomura, Toshimasa Yamauchi

“…Hence, this study identifies a NIC-triggered pathway regulating the stemness and tumorigenicity of ISCs and suggests the use of DBZ as a potential therapeutic strategy for treating intestinal tumors.…”
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Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus by Maheswata Sahoo, Lingaraja Jena, Sangeeta Daf, Satish Kumar

“…The protease activity of NS3 is necessary for viral replication and its prohibition could be considered as a strategy for treatment of ZIKV infection. Amongst these four drugs, berberine has shown highest binding affinity of –5.8 kcal/mol and it is binding around the active site region of the receptor. …”
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Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasi... by Rigaud, Thierry, Balourdet, Aude, Bauer, Alexandre

“…The acanthocephalan Pomphorynchus laevis, a fish intestinal helminth, infecting freshwater gammarid amphipods as intermediate hosts, is using such a strategy of protection-then-exposure to predation by the definitive host. …”
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Full-space trifunctional metasurface with independent control of amplitude and phase for circularly polarized waves by Li Xi Ming, Zhao Yuan, Lu Ren Pan, Sun Xiao Feng, Yang Zhao, He Hai Dan, Liu Yan Hui, Du Guo Hong

“…Herein, an innovative strategy of trifunctional metasurface is proposed to independently and simultaneously manipulate the amplitude and phase of circular polarized waves in full space. …”
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lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587 by Xirui Ma, Ziming Mao, Jing Zhu, Huifang Liu, Fengling Chen

“…Due to its poor diagnosis strategy and inefficient clinical intervention, HCC has brought terrible life experiences for patients worldwide. …”
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Is in situ simulation in emergency medicine safe? A scoping review by Guillaume Martel, Andrew Petrosoniak, Marcel Émond, Jennifer Truchot, Valérie Boucher, Éliane Raymond-Dufresne, Winny Li, Eva Jouhair

“…Objectives To provide an overview of the available evidence regarding the safety of in situ simulation (ISS) in the emergency department (ED).Design Scoping review.Methods Original articles published before March 2021 were included if they investigated the use of ISS in the field of emergency medicine.Information sources MEDLINE, EMBASE, Cochrane and Web of Science.Results A total of 4077 records were identified by our search strategy and 2476 abstracts were screened. One hundred and thirty full articles were reviewed and 81 full articles were included. …”
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Effectiveness of Sports-Based Interventions for Mental Health in At-Risk Youth: A Systematic Review by Katarzyna Rowińska, Karolina Siembab, Daria Bednarczyk, Julia Białeta, Agnieszka Napieralska, Alicja Černohorská, Wiktor Garbarczyk, Michalina Jurkiewicz, Albert Kapla, Wiktoria Pysiewicz

“…Sports-based interventions have emerged as a promising strategy to promote mental health by leveraging the psychological and social benefits of physical activity. …”
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Renal failure due to rectal neoplastic polyp: McKittrick–Wheelock syndrome—a case report by Ivan Valentinov Dimitrov, Theophil Angelov Sedloev, Ivan Petrov Vasilev, Slavyana Slavcheva Usheva, Yavor Asenov Nikolov, Nikolay Metodiev Penkov, Plamen Ivanov Penchev, Maria-Elena Boyadzhieva, Georgi Chavdarov Jelev

“…Employing a multidisciplinary strategy that includes prompt recognition, timely intervention, and thorough preoperative stabilization is crucial for achieving successful outcomes.…”
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Ankle muscle strength and activation are associated with walking patterns in preschool and school-age children. by Sudarat Apibantaweesakul, Shiho Omura, Weihuang Qi, Natsuki Sado, Hiroto Shiotani, Fumiko Tanaka, Plaiwan Suttanon, Yasuo Kawakami

“…We investigated musculature, biomechanics, and muscle activation strategies and their relevance to walking performance in preschool (PS) and school children (SC), with adults (AD) as reference. …”
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Left atrial appendage cannulation for left ventricular unloading in a patient with ventricular thrombus on extracorporeal life support by Anne-Kristin Schaefer, Dominik Wiedemann, Gottfried Heinz, Julia Riebandt, Robert Zilberszac

“…However, intraoperative TEE showed resolution of the LV thrombus, enabling to change the strategy to left ventricular assist device implantation only, which was performed successfully. …”
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The Effect of Sensorimotor Synchronization on Gait Spatiotemporal Parameters in Women with Multiple Sclerosis by Mozhgan Memarmoghadam, Mansoureh Shahraki, Behzad Mohammadi Orangi, Luca Correale, Leonardo A. Peyré-Tartaruga

“…Conclusion: Therefore, synchronizing gait with a rhythmic visual stimulus can be an effective therapeutic strategy to improve gait and main temporal parameters in patients with MS. …”
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Endoscopic endonasal approach for pituitary neuroendocrine tumor with septal mucosa incision tailored to tumor extension intending unilateral septal mucosa preservation by Hiroyoshi Kino, Hiroyoshi Akutsu, Shuho Tanaka, Takuma Hara, Yusuke Morinaga, Hidetaka Miyamoto, Rieko Ii, Koutarou Osawa, Eiichi Ishikawa

“…Thus, PTSA with K-R incision was effective in preserving the nasal septal mucosa on one side and gaining a sufficient surgical corridor with lateral expansion of the anterior sphenoidotomy on the other side. Our strategy may be preferable to improve maneuverability of instruments during tumor resection.…”
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The Effectiveness of Novel Growth Regulator and Fertilizer to Improve Quality and Yield of Spring Wheat by Shimendi G. Okbagabir, Mohammed H. Al-Mamoori, Elena N. Pakina, Meysamr Zargar

“…In conclusion, proficient handling of plant growth regulators (PGR) and fertilizers (F) can be considered as a crop management strategy to boost yield and quality by improving chemical fertilization, utilization efficiency, and reducing environmental pollution. …”
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Designing social behaviour change in households: sustainable mobility intervention and follow-up study by Saga Sofia Santala, Saga Sofia Santala, Merja Honkanen, Michael Lettenmeier, Michael Lettenmeier, Michael Lettenmeier, Jari Kolehmainen, Salla Lahtinen

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Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway by Yifan Lai, Jiawei Qiu, Kuang Zheng, Xiang Li, Yinuo Lin, Zhengzheng Li, Haiqiu Sun

“…Overall, our results suggest that metformin may represent a promising and innovative therapeutic strategy for mitigating the onset of hearing loss.…”
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Identifying Incident Causal Factors to Improve Aviation Transportation Safety: Proposing a Deep Learning Approach by Tianxi Dong, Qiwei Yang, Nima Ebadi, Xin Robert Luo, Paul Rad

“…Prevention is clearly the best strategy for aviation transportation safety. Learning from past incident data to prevent potential accidents from happening has proved to be a successful approach. …”
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Advertising as a tool to stimulate the sales market of construction company services by N. M. Suray, M. A. Vasilenko

“…The urgency of this study is due to the constant growth of demand for residential real estate, which requires effective marketing strategies to attract customers. The aim of the work is to analyze the methods and techniques of advertising used by these construction organizations. …”
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Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease by Stephanie French, Rachael Da Silva, Janet Storm, Christida E. Wastika, India Cullen, Martijn ten Have, Grant L. Hughes, Cassandra M. Modahl

“…In terms of mosquito-borne diseases, paratransgenesis strategies have been developed to target Plasmodium. …”
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Retrotransposon-Based Genetic Diversity of <i>Rhodiola rosea</i> L. (Crassulaceae) from Kazakhstan Altai by Oxana Khapilina, Ainur Turzhanova, Moldir Zhumagul, Damelya Tagimanova, Olesya Raiser, Serik Kubentayev, Vladislav Shevtsov, Maria Hohn

“…The analysis of genetic diversity in natural populations of valuable medicinal plant species experiencing overexploitation is a key aspect of their natural conservation strategy. Mobile genetic elements and other interspersed repeats, which are major components of eukaryotic genomes, serve as effective tools for studying plant biodiversity and variability. …”
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Case report: Movement-related neuroplasticity in a patient after spinal cord injury in response to task-oriented bimanual training by Di Ma, Roy Rongyue Zeng, Sofina Sy Chan, Yu Pan, Jack Jiaqi Zhang

“…BackgroundBimanual motor training is an effective neurological rehabilitation strategy. However, its use has rarely been investigated in patients with paralysis caused by spinal cord injury (SCI). …”
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