How close is autophagy-targeting therapy for Alzheimer's disease to clinical use? A summary of autophagy modulators in clinical studies by Sofia Miranda Fernandes, Johanna Mayer, Per Nilsson, Makoto Shimozawa

“…Modulating autophagy has been proposed as a therapeutic strategy for AD because of its potential to clear aggregated proteins. …”
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Research on a New Control System Based on L1 Adaptive Control Scheme for the Voice Coil Motor by Huaiguo Jing, Ying Li, Bo Li, Shuo Huang, RuiDian Zhan, Hao Li, Xuexi Zhang

“…Therefore, in order to better solve the problem of dynamic parameter uncertainty, external load disturbance, and tracking control of the voice coil motor servo system in motion, this paper proposes for the first time the strategy of using L1 adaptive control algorithm to control the voice coil motor servo system. …”
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Fractional order slide mode droop control for simultaneous voltage and frequency regulation of AC microgrid by Mohamad Issa Ibraheem, Mehdi Edrisi, Hassan Haes Alhelou, Mehdi Gholipour

“…The sliding mode control (SMC) strategy is normally used to control linear equations. …”
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Direct coupling analysis and the attention mechanism by Francesco Caredda, Andrea Pagnani

“…Additionally, the functional form of the energy function of the model enables us to deploy a multi-family learning strategy, allowing us to effectively integrate information across multiple protein families, whereas standard DCA algorithms are typically limited to single protein families. …”
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Review of an Improved Longwall Panel Layout for Ground Control in Longwall Mining by Z. M. Cui, P. F. Wang, Z. Li, Y. Yang

“…Theoretical, numerical analysis, and field observation results of the new strategy demonstrate that the problems mentioned above in CLL are mitigated, and the development entries using the improved longwall system have a better stress environment with associated reduction in large roadway convergence, coal bumps or outbursts, and many other issues on ground control. …”
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Maximizing network throughput by cooperative reinforcement learning in clustered solar-powered wireless sensor networks by Yujia Ge, Yurong Nan, Xianhai Guo

“…This article proposes an adaptive power manager based on cooperative reinforcement learning methods for the solar-powered wireless sensor networks to keep harvested energy more balanced among the whole clustered network. The cooperative strategy of Q -learning and SARSA( λ ) is applied in this multi-agent environment based on the node residual energy, the predicted harvested energy for the next time slot, and cluster head energy information. …”
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Exogenous Surfactant Therapy for Pediatric Patients with Acute Respiratory Distress Syndrome by James F Lewis, Jasvinder S Dhillon, Ram N Singh, Craig C Johnson, Timothy C Frewen

“…Based on the results of this pilot study, a more appropriate multicentre clinical trial should be designed to evaluate this treatment strategy.…”
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Ligating the varicose vein trunk for bleeding stomal varices in portal hypertension: a case report by Jialiang Sun, Zhanhai Tan, Jifa Zhang

“…Our team’s approach through blocking the primary trunk of variceal vein via a minimal incision under local anesthesia may offer a new treatment strategy for patients with poor liver function who cannot withstand the trauma associated with general anesthesia and major surgery.…”
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Comparative transcriptome analysis in two contrasting genotypes for Sclerotinia sclerotiorum resistance in sunflower. by Mingzhu Zhao, Bing Yi, Xiaohong Liu, Dexing Wang, Dianxiu Song, Enyu Sun, Liangji Cui, Jingang Liu, Liangshan Feng

“…Sclerotinia sclerotiorum as a necrotrophic fungus causes the devastating diseases in many important oilseed crops worldwide. The preferred strategy for controlling S. sclerotiorum is to develop resistant varieties, but the molecular mechanisms underlying S. sclerotiorum resistance remain poorly defined in sunflower (Helianthus annuus). …”
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Secure software development: leveraging application call graphs to detect security vulnerabilities by Lei Yan, Guanghuai Zhao, Xiaohui Li, Pengxuan Sun

“…This article introduces a thorough method for detecting vulnerabilities using dynamic and static analysis, focusing on a cryptographic function dominance tree. This strategy systematically minimizes the likelihood of integrity breaches in cryptographic applications. …”
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(Re-)Positioning and recognising the influence of internal communication on employee engagement for maximum organisational performance by Tsietsi Mmutle

“…Although some evidence exists on the relationship between internal communication strategies and employee engagement outcomes, the accentuated value that can be derived from internal communication practice is yet to be fully explored. …”
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Unstructured Grid Solutions for Incompressible Laminar Flow over a Circular Cylinder Using a Particular Finite Volume-Finite Element Method by Mahdi Yousefifard, Parviz Ghadimi, Rahim Zamanian

“…Results have been compared with the structured grid results, both cases with equal cell numbers and same strategy for the mesh refinement. Current results display good agreement with the experimental values. …”
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Model-free current control solution employing intelligent control for enhanced motor drive performance by Muhammad Usama, Jaehong Kim

“…Abstract The study presents an intelligent, model-free current control strategy that eliminates the need for explicit plant models while efficiently reducing the effect of plant parameter perturbation. …”
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THE PHENOMENON OF FLAGSHIP UNIVERSITIES OF REGIONAL ECONOMY IN MODERN RUSSIA by S. A. IVANOV, E. N. SOKOL-NOMOKONOV

“…The paper considers features of universities activity which focus on solving problems of the development of the regional economy; features of flagship universities activity of the regional economy in the context of the “Strategy for Scientific and Technological Development of the Russian Federation”. …”
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Minimally processed fruits with added probiotics: A review by Vanessa Caroline de Oliveira, Maria José do Amaral e Paiva, Daniele Juliana Rodrigues Gonçalves, Nataly de Almeida Costa, Érica Nascif Rufino Vieira, Bruno Ricardo de Castro Leite Júnior

“…In parallel, the review presents the viability of probiotics in minimally processed fruits, the challenges encountered and the best strategy for the incorporation of these microorganisms into plant matrices. …”
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Interaction of Schistosoma mansoni Sporocysts and Hemocytes of Biomphalaria by D. Negrão-Corrêa, A. C. A. Mattos, C. A. J. Pereira, R. L. Martins-Souza, P. M. Z. Coelho

“…The schistosome-resistant Biomphalaria can be an alternative strategy for the control of schistosomiasis.…”
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Aptamers: A Feasible Technology in Cancer Immunotherapy by M. M. Soldevilla, H. Villanueva, F. Pastor

“…The advantages provided by aptamers could enhance the therapeutic index of a given strategy and therefore enhance the antitumor effect. …”
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Barriers and pathways to environmental surveillance of antibiotic resistance in middle- and low-income settings: a qualitative exploratory key expert study by Ann-Christin Peters, D. G. Joakim Larsson, Ramanan Laxminarayan, Christian Munthe

“…Environmental surveillance solutions are increasingly highlighted as a strategy to help overcome such problems, and thus to promote global health as well as the local management of ABR in LMI countries. …”
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From Concept to Creation by Maricica STOICA, Carmelia Mariana BĂLĂNICĂ-DRAGOMIR, Cezar Ionuț BICHESCU, Alina Mihaela CEOROMILA, Angela Stela IVAN, Larisa ȘAVGA, Dimitrie STOICA

“…The results highlight the importance of a balanced strategy for idea generation to promote effective and sustainable innovations in food product development. …”
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Time-Series Load Online Prediction of Wind Turbine Based on Adaptive Multisource Operational Data Fusion by Ruojin Wang, Xiaodong Wang, Deyi Fu, Bin Yang, Yingming Liu

“…According to the 15 MW semisubmersible offshore WTG load prediction example, the prediction error of this method is about 4% under normal data conditions and 6% under abnormal data conditions, and the calculation time of 200 sets of test data is 0.053 s, which meets the needs of pitch control and has the potential to be applied in the optimization of pitch control strategy.…”
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