Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms by Monika Jürgenson, Keerthana Chithanathan, Aivar Orav, Külli Jaako, Janeli Viil, Mithu Guha, Kalev Kask, Alexander Zharkovsky

“…These findings provide valuable insights into the anti-obesity mechanisms of fluorinated D-vitamin analogs and suggest potential therapeutic strategies for obesity prevention.…”
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Optimized methods for the targeted surveillance of extended-spectrum beta-lactamase-producing Escherichia coli in human stool by Sarah Gallichan, Sally Forrest, Esther Picton-Barlow, Claudia McKeown, Maria Moore, Eva Heinz, Nicholas A. Feasey, Joseph M. Lewis, Fabrice E. Graf

“…ABSTRACT Understanding transmission pathways of important opportunistic, drug-resistant pathogens, such as extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli, is essential to implementing targeted prevention strategies to interrupt transmission and reduce the number of infections. …”
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An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced bi... by Shaker Hassan S. Alshehri, Mastour Saeed Alshahrani, Saeed Y. Al Adal, Faisal M. Alyazedi, Hani Hassan Alnakhli, Ravi Shankar Reddy

“…Integrating cognitive-behavioral strategies may enhance proprioceptive accuracy and stability outcomes in this population.…”
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Prevalence of attention deficit hyperactive disorder (ADHD) symptoms in selected government primary schools in Wakiso District, Uganda by Josephine Ssirimuzaawo, Miph Musoke, Pio Frank Kiyingi

“…Practical implications – The researcher recommends that further research is needed in other districts; also, there is a need to develop early intervention strategies for teachers and parents with ADHD children. …”
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A nomogram model based on albumin-bilirubin score for predicting 90-day prognosis in patients with acute-on-chronic liver failure by Wei Ding, Wei Ding, Jiandong Shen, Li Zhang, Li Zhang, Jianguo Shao, Zhaolian Bian, Hong Xue

“…Calibration curves demonstrated the accuracy of the model, and DCA results suggested that the model was clinically useful when the threshold was below 0.6.ConclusionThe nomogram model incorporating ALBI with CR, Gender and ascites can predict the 90-day prognosis of ACLF patients, potentially helping to optimize treatment strategies and improve patient outcomes.…”
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MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS by Chunlai Yin, Xue Yan, Jinyi Ren, Cheng Zhang, Jiaqing Liu, Zilong Wang, Jing Liu, Weiping Li, Xia Li

“…These findings provide novel insights into MDS MSCs-metabolism-Exosome axis in ineffective hematopoiesis and offer new strategies for the treatment of MDS.…”
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PROSPECTS FOR THE DEVELOPMENT OF BIODIESEL PRODUCTION IN UKRAINE WITH CONSIDERATION OF SOCIO-ECONOMIC AND ENVIRONMENTAL EFFICIENCY by Ihor Kupchuk, Tatiana Yemchyk, Yaroslav Gontaruk

“…The research findings can be used to develop effective strategies for promoting bioenergy in Ukraine. Practical implications. …”
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Sociodemographic index–age differences in the global prevalence of cardiovascular diseases, 1990–2019: a population-based study by Xunliang Li, Channa Zhao, Mengqian Liu, Wenman Zhao, Haifeng Pan, Deguang Wang

“…While the global prevalence of CVD has generally decreased, the rise in CVD prevalence in lower SDI countries and younger populations calls for tailored intervention strategies. Addressing these disparities is crucial to mitigating the growing burden of CVD and promoting cardiovascular health on a global scale.…”
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No rumen fermentation profiles and associated microbial diversities difference were found between Hu sheep and Karakul sheep fed a cottonseed hull diet by Jishu Wang, Guangxu E, Meng Zhang, Yanlong Zhang, Tiantian Bai, XuanXuan Pu, Junfeng Liu, Xuefeng Guo, Subir Sarker, Long Cheng

“…These results provide a scientific basis for further understanding the rumen function of sheep and for optimizing their feeding strategies. Video Abstract…”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…Sustainable control strategies are urgently needed including the exploration of medicinal plants as safer alternatives to chemical anthelmintics. …”
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Acquiring Pragmatic Competence during Short-Term Study Abroad: The Service Encounter Request by Todd Hernández, Paulo Boero

“…Further, the SA participants’ request strategies also improved in both scenarios. Findings indicated that incorporating pragmatic instruction before and during students’ SA experience is an effective method for facilitating their L2 pragmatic development. …”
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Immunological mechanisms of tuberculosis susceptibility in TB-infected individuals with type 2 diabetes mellitus: insights from mycobacterial growth inhibition assay and cytokine a... by Bindu Dasan, Anuradha Rajamanickam, Arul Nancy Pandiarajan, Sivakumar Shanmugam, Sujatha Nott, Subash Babu

“…The findings also highlight the importance of integrated care strategies for managing both T2DM and TB, particularly in TB-endemic regions, and point to the need for further research to develop more effective interventions tailored to this vulnerable population.…”
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Healthy aging in frail older adults: Active aging project of a national survey by Jisu Seo, Kyungok Joo, Yuelin Li, Nayoung Kim, Eunna Oh, Lkhagvajav Gansukh, Rhayun Song

“…Conclusion: Cognitive and physical function, alongside resilience and social support as mediators, significantly associated with healthy aging in frail older adults through daily activity. Health promotion strategies could focus on resilience and social support to empower individuals and strengthen social connectedness, thereby supporting independence in daily life and healthy aging. …”
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Biosynthesis, characterization, and in-vitro anticancer effect of plant-mediated silver nanoparticles using Acalypha indica Linn: In-silico approach by Luailik Madaniyah, Saidun Fiddaroini, Elok Kamilah Hayati, Moh. Farid Rahman, Akhmad Sabarudin

“…The World Health Organization emphasizes the need for effective prevention, early detection, and treatment strategies to address this public health challenge. …”
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Assessment of hand hygiene practices among nurses at a regional hospital in Kandahar, Afghanistan: A cross-sectional study based on the World Health Organization (WHO) ‘Your 5 Mome... by Abdul Qadeer Baseer, Asmatullah Usmani, Shafiqullah Mushfiq, Mohammad Hassan Hassand, Bilal Ahmad Rahimi, Abdul Wahid Monib, Mohammad Salim Daqiq, Parwiz Niazi

“…Enhanced training programs, tailored strategies, and regular audits are essential for improving hand hygiene practices and strengthening infection prevention and control efforts, ultimately enhancing patient safety in resource-limited settings. …”
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Challenges of Corporate Misconduct: The Organisational, Social, Economic and Financial Dynamics of Workplace Sexual Harassment in the Restaurant Industry in the USA by Darrell Norman Burrell, Stacey L. Morin, Theresia Wansi, Virginia Bianco Mathis, Carlo Ninassi, Susanne Ninassi

“…By examining a real-world case study, the research offers insights into how these dynamics manifest in practice, contributing to actionable strategies for fostering a safer, more respectful workplace. …”
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Short- and long-term changes in neurological, behavioural, and blood biomarkers following repeated mild traumatic brain injury in rats—potential biological sex-dependent effects by Rodrigo Moraga-Amaro, Oscar Moreno, Jordi Llop, Marion Bankstahl, Marion Bankstahl, Jens P. Bankstahl

“…New approaches to early diagnose this disease are crucial to facilitate the translation of novel treatment strategies to the clinic. Several studies have found suitable candidate biomarkers, but the results are not straightforward. …”
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The Role of School Management Committee and Pupils' Performance in Government Primary Schools in RuhiJa Town Council Rubanda District. by Niwagaba, Alex

“…The recommendations included; the school management committee through meetings with members of teaching staff and their head teachers should advise them properly and allow them to execute their duties as expected in order to alleviate levels of understanding to children that lead to excellent academic performance; more research should be carried out to allow the school management committees not to dwell on advising head teachers only on matters of children's performance by suggesting strategies but also the entire stakeholders whose effort can promote academic performance of children in primary schools; need to formulate academic committees advised by the members of school management committee on how to perform through motivational element aiming at doing well academically to promote the names of the school; it is imperative that the schools get in touch with the members of the school management committees who have some formal education to quickly understand the value of education and how plans for developments of certain sectors in school especially academic performance could be made; need to foster supervision that involves cooperation towards pupils 'performance by all stakeholders; appointing an active team that can do supervision to let children advance academically is healthy.…”
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Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in sub-Saharan Africa: a systematic review and... by Mwesigwa, Alex, Ocan, Moses, Musinguzi, Benson, Nante, Rachel Wangi, Nankabirwa, Joaniter I., Kiwuwa, Steven M., Kinengyere, Alison Annet, Castelnuovo, Barbara, Karamagi, Charles, Obuku, Ekwaro A., Nsobya, Samuel L., Mbulaiteye, Sam M., Byakika‐Kibwika, Pauline

“…These findings suggest a need for malaria control strategies and surveillance efforts considering regional-specific factors underlying Plasmodium falciparum infection.…”
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Human Resource Practices and Employee Retention in Local Governments in Uganda: A Case of Kabale District Local Government. by Baingana, Alex

“…The study recommended that it is crucial for KDLG to reevaluate its retention strategies, focusing on enhancing job satisfaction, professional development opportunities, and overall workplace conditions to mitigate turnover and ensure the retention of valuable talent. …”
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