Epidemiology of Soft Tissue Sarcoma in Iran: Four‐Year National Cancer Registry Data Report (2014–2017) by Mohammad Sajed Dehghan Banadaki, Vahid Rahmanian, Saeed Hosseini, Seyyed Mohammad Hossein Hosseini, Narjes Hazar

“…To develop effective preventive and treatment strategies for STS, it is essential to gain a deeper understanding of the epidemiological trends associated with the disease. …”
Get full text

Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis by Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie

“…Abstract Background Current research underscores the need to better understand the pathogenic mechanisms and treatment strategies for idiopathic pulmonary fibrosis (IPF). …”
Get full text

Impact of COVID-19 pandemic measures on hospitalizations and epidemiological patterns of twelve respiratory pathogens in children with acute respiratory infections in southern Chin... by Wei Wang, Xiaojuan Luo, Zhenmin Ren, Xiaoying Fu, Yunsheng Chen, WenJian Wang, Yanmin Bao, Yuejie Zheng, Ke Cao, Jiehua Chen

“…Continuous monitoring of these patterns is essential to understand the duration of these effects and to inform effective response strategies.…”
Get full text

Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach by Josep Garcia-Llorens, Isaac Monroy, Jan Torres-Boncompte, Jose M. Soriano, Pablo Catalá-Gregori, Sandra Sevilla-Navarro

“…<b>Conclusions</b>: These findings highlight the critical need for targeted surveillance and intervention strategies in poultry production to mitigate the risks posed by MDR <i>Enterococcus</i> to public health.…”
Get full text

ARAHAN PENGEMBANGAN PARIWISATA DI KECAMATAN DUSUN SELATAN, KABUPATEN BARITO SELATAN PROPINSI KALIMANTAN TENGAH by AZARINE HANA BASTIYANI, IRA SAFITRI

“…Setelah dianalisis menggunakan metode di atas, kemudian dilakukan analisis SWOT untuk mengetahui strategi yang nantinya akan menjadi arahan pengembangan yang ada di setiap SKP yang ada di SWP Dusun Selatan. …”
Get full text

Impact of Prone Position on 12-Lead Electrocardiogram in Healthy Adults: A Comparison Study with Standard Electrocardiogram by Yunis Daralammouri, Murad Azamtta, Hamza Hamayel, Amro Adas, Osama Sawalmeh, Yahia Ismail, Saed H. Zyoud

“…Prone position ECG resulted in significant changes in healthy adults that should be aware of this as this can affect diagnosis and management strategies. Further studies are needed to investigate the impact of prone position on ECG recording in patients with cardiovascular diseases.…”
Get full text

Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy by Sjoerd H van der Burg, Marjolein Sluijter, Thorbald van Hall, Jim Middelburg, Kristel Kemper, Janine Schuurman, Gaby Schaap, Katy Lloyd, Vitalijs Ovcinnikovs

“…Here, we examined multiple combination strategies aiming to improve survival rates in solid tumors and, simultaneously, install endogenous immunity capable of protection to tumor rechallenge.Methods Two syngeneic mouse tumor models were employed: The immunologically “cold” B16F10 melanoma and the immunologically “hot” MC38.TRP1 colon carcinoma model. …”
Get full text

A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response by Minghan Li, Chang Su, Qianru Wang, Yuetong Chen, Di Jiang, Weijia Wang, Shunjin Chen, Xiangping Li, Ming Fu, Juan Lu

“…Our results highlight the important role of ZNF32 in tumorigenesis and provide novel perspectives for potential cancer treatment strategies.…”
Get full text

Assessing caregiver stress and resource needs in pediatric cancer care by Shaimaa Mohamed Amin, Mahmoud Abdelwahab Khedr, Azza Medhat Aziz Mansy, Ahmed Hashem El-Monshed, Mohamed Gamal Noaman Malek, Ayman Mohamed El-Ashry

“…Future research should explore sustainable strategies to further reduce caregiver burden. Clinical trial number Not applicable.…”
Get full text

Elucidating the Role of HIF-1&alpha;/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study by Zhao HW, Liu ST, Wang XJ, Zhang XM, Ma X

“…Understanding the mechanisms of periodontitis, particularly the role of hypoxia in inflammation, is critical for identifying novel therapeutic strategies. This study investigated the effects of the prolyl hydroxylase (PHD) inhibitor DMOG on pro-inflammatory cytokine expression in human periodontal ligament stem cells (hPDLSCs) and examined the involvement of the HIF-1α/YAP signaling path ay in modulating inflammation.Materials and Methods: hPDLSCs were cultured and treated with lipopolysaccharide (LPS) to induce inflammation, followed by DMOG treatment. …”
Get full text

The indirect role of perceived survival expectations in the association between perceived hope and suicidal thoughts among palestinians amid war in Gaza by Feten Fekih-Romdhane, Kamel Jebreen, Tasnim Swaitti, Mohammed Jebreen, Eqbal Radwan, Wafa Kammoun-Rebai, Mahmoud A. Abu Samra, Asmaa Abusamra, Sahar Obeid, Souheil Hallit

“…Abstract Understanding how hope can be protective against suicide may improve prevention efficiency by helping identify and target those most at risk for suicide, and develop individualized treatment strategies. However, no studies have yet focused on the processes underlying the relationship between hope and suicidality in war-affected populations. …”
Get full text

Evaluation of the Psychiatric Disorders among Amphetamine Addicts in Rehabilitation Centers: A Cross-Sectional Analysis by Saud D. AlOtaibi, Hossam A. Elsisi, Mohammed J. AlShammary, Saud A. AlQader, Hejab A. AlHarbi, Bayan R. AlOlaiyan, Ahmad O. Alanazi, Firas S. AlMendeel, Yazeed N. AlHarbi, Ibrahim AlKhalaf, Ahmad H. Alhowail, Abdelhamid Mohamed Elwy, Ashraf M. Emara

“…Therefore, this research aimed to examine conditions such as depression, anxiety, mood, cognitive abilities at the workplace, and social responsibilities by using sociodemographic factors as useful tools in determining effective strategies for preventing, managing, and treating amphetamine addiction. …”
Get full text

Recruiting participants for focus groups in health research: a meta-research study by Jonas Lander, Simon Wallraf, Dawid Pieper, Ronny Klawunn, Hala Altawil, Marie-Luise Dierks, Cosima John

“…Researchers may benefit from more practical support, such as early training on key principles and options for effective recruitment strategies provided by institutions in their immediate professional environment, e.g. universities, faculties or scientific associations.…”
Get full text

Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons by Huizi Li, Shishi Wang, Ruihong Guo, Xijiao Chen, Yuanyuan Huang, Weixin Jia, Zhangyong Ning

“…To verify the role of C4BPM in replication of AIVs, C4BPM knockout (C4BPM-KO) and stable overexpressing (C4BPM-overexpressing) DF-1 cells were generated using lentivirus-mediated CRISPR/Cas9 gene editing technology and molecular cloning strategies. Replication of H5N1 and H9N2 AIVs were promoted in C4BPM-overexpressing DF-1 cells with inhibited expression of type I IFNs (IFN-α, IFN-β), protein kinase R (PKR), cholesterol 25-hydroxylase (CH25H), interferon regulatory factor (IRF) 3, and mitochondrial antiviral signaling protein (MAVS) compared to that of the DF-1 cells. …”
Get full text

Assessing and optimizing the potential for climate change mitigation and carbon sequestration in urban residential green spaces: energizing sustainable cities by Hancheng Liu, Jialong Zhang, Zijun Wang

“…Additionally, CO2 concentrations were monitored across the four residential areas, providing insights into the spatial and temporal dynamics of carbon sequestration.DiscussionBased on the findings, optimization strategies were proposed, such as prioritizing the selection and integration of high-performing evergreen tree species in urban green space design and incorporating diverse plant types to enhance year-round carbon sequestration. …”
Get full text

OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer by Qihui Sun, Xiaoqi Zhu, Qi Zou, Yang Chen, Tingting Wen, Tingting Jiang, Xiaojia Li, Fang Wei, Keping Xie, Jia Liu

“…Identifying key factors that regulate the immunosuppressive landscape is crucial for improving treatment strategies. Methods We constructed a prognostic and risk assessment model for pancreatic cancer using 101 machine learning algorithms, identifying OSBPL3 as a key gene associated with disease progression and prognosis. …”
Get full text

Spatial Distribution of Tsetse Flies and Trypanosome Infection Status in a Vector Genetic Transition Zone in Northern Uganda by Robert Opiro, Okello Allele Moses, Robert Opoke, Francis A. Oloya, Esther Nakafu, Teresa Iwiru, Richard Echodu, Geoffrey M. Malinga, Joel L. Bargul, Elizabeth A. Opiyo

“…Reliable data on the vector distribution and the trypanosome species they carry is pertinent for planning sustainable control strategies. This study was carried out to estimate the spatial distribution, apparent density, and trypanosome infection rates of tsetse flies in two districts that fall within a vector genetic transition zone in northern Uganda. …”
Get full text

Enhancing food security while reducing environmental impacts: Life cycle assessment of cultivation-irrigation systems and yield gap closure in paddy fields by Abdullah Darzi-Naftchali, Markus Berger, Fereshteh Batoukhteh, Ali Motevali

“…Based on the results, incorporating YG reduction strategies in DDSR-D can enhance the environmental sustainability of rice production and accelerate progress toward achieving sustainable development goals.…”
Get full text

Temporally enhanced RSEI and nighttime lights reveal long-term ecological changes and effective protection in China’s inaugural national parks by Chunhui Wen, Tengfei Long, Guojin He, Weili Jiao, Wei Jiang

“…Rational assessments of long-term change in ecological environment quality within these areas are crucial for informing effective conservation strategies and policy decisions. This study addresses the challenges of long-term ecological monitoring by improving the Remote Sensing Ecological Index (RSEI) to analyze spatiotemporal changes in ecological quality of China’s inaugural national parks (NPs) from 2000 to 2022. …”
Get full text

A Phenomenological Study of the Role of Store Mannequins on the Experienced Responses of Generation-Y Female Customers by Kobra Najafi, Kambiz Heidarzadeh Hanzaee, Mohsen Khounsiavash

“…By recognizing the effects of visual stimuli (mannequins), retailers can use marketing strategies to create a good shopping experience. According to the findings from the motivational tool, mannequins prove to be effective in fostering a positive attitude among customers. …”
Get full text