Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021 by Xi Chen, Xi Chen, Dandan Ma, Hangyu Li, Yilin Liu, Guixing Xu, Xinyu Deng, Qi Li, Junqi Li, Hui Pan

“…Continuous monitoring and age-targeted interventions are essential. Future healthcare strategies must address the aging population to manage the projected increase in asthma cases and deaths.…”
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The impact of dietary phosphorus levels on growth, slaughter, and digestive metabolism in growing sheep by Shoupei Zhao, Xiaojun Ni, Jia Zhou, Xiaoqi Zhao, Xiao Wen, Xiaolin Wang, Mingyu Cao, Yanfei Zhao, Chong Shao, Lianghao Lu, Yuanyuan Chen, Bao Zhang, Huaming Yang, Bai Xue, Guobo Quan

“…The recommended dietary P level was 0.40%, with maintenance and growth requirements of 0.06 g/EBW and 5.34–6.19 g/kg EBW, respectively, providing a foundation for P reduction strategies.…”
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Social determinants of oral health in an indigenous community of Chile: preliminary data of a mixed qualitative and quantitative study by Cynthia Cantarutti, Gerardo Yévenes, Agueda Muñoz-del-Carpio-Toia, Daniela Adorno-Farias, Ricardo Fernández-Ramires, Alan Roger Santos-Silva, Jean Nunes dos Santos, Ignacio Molina-Ávila, Wilfredo Alejandro González-Arriagada

“…We emphasize the need for implementing strategies for oral health promotion and prevention that consider cultural, linguistic and specific needs of these communities.…”
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Explore the evolution of winter wheat production and its response to climate change under varying precipitation years in the Loess Plateau of China by Donglin Wang, Yanbin Li, Binbin Zhang, Tengcong Jiang, Siyu Wu, Wenjie Wu, Yi Li, Jianqiang He, Deli Liu, Qinge Dong, Hao Feng

“…This study provides an important reference for formulating long term adaptation strategies to enhance the resilience of agricultural production against climate change.…”
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Climate response to stratospheric aerosol injection during the Harmattan season in West Africa by Francis Nkrumah, Gandome Mayeul Leger Davy Quenum, Kwesi A Quagraine, Simone Tilmes, Nana Ama Browne Klutse, Atanas Dommo, Hubert A Koffi, Patrick Essien, Rebecca Bediako

“…These findings also highlight the potential for SAI to improve air quality in certain areas but also underscore the need for careful consideration of implementation strategies and possible trade-offs. The changes from SAI observed are specific to the ARISE simulation and may differ from other SAI simulations.…”
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Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight man... by Hiba Jebeile, Natalie B Lister, Sol Libesman, Kylie E Hunter, Caitlin M McMaster, Brittany J Johnson, Louise A Baur, Susan J Paxton, Sarah P Garnett, Amy L Ahern, Denise E Wilfley, Sarah Maguire, Amanda Sainsbury, Katharine Steinbeck, Lisa Askie, Caroline Braet, Andrew J Hill, Dasha Nicholls, Rebecca A Jones, Genevieve Dammery, Alicia M Grunseit, Kelly Cooper, Theodore K Kyle, Faith A Heeren, Fiona Quigley, Rachel D Barnes, Melanie K Bean, Kristine Beaulieu, Maxine Bonham, Kerri N Boutelle, Braulio Henrique Magnani Branco, Simona Calugi, Michelle I Cardel, Kelly Carpenter, Hoi Lun Cheng, Riccardo Dalle Grave, Yngvild S Danielsen, Marcelo Demarzo, Aimee Dordevic, Dawn M Eichen, Andrea B Goldschmidt, Anja Hilbert, Katrijn Houben, Mara Lofrano do Prado, Corby K Martin, Anne McTiernan, Janell L Mensinger, Carly Pacanowski, Wagner Luiz do Prado, Sofia M Ramalho, Hollie A Raynor, Elizabeth Rieger, Eric Robinson, Vera Salvo, Nancy E Sherwood, Sharon A Simpson, Hanna F Skjakodegard, Evelyn Smith, Stephanie Partridge, Marian Tanofsky-Kraff, Rachael W Taylor, Annelies Van Eyck, Krista A Varady, Alaina P Vidmar, Victoria Whitelock, Jack Yanovski, Anna L Seidler, Eating Disorders In weight-related Therapy (EDIT) Collaboration

“…The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. …”
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Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America by Lilian Da Silva Santos, Hans Wolff, François Chappuis, Pedro Albajar-Viñas, Marco Vitoria, Nguyen-Toan Tran, Stéphanie Baggio, Giuseppe Togni, Nicolas Vuilleumier, François Girardin, Francesco Negro, Laurent Gétaz

“…To conclude, the high prevalence rates of persistent viral and parasitic infections and their potential coinfections among SSA and LA detained migrants highlight the need to implement control strategies and programs that reach people in detention centers in nonendemic countries.…”
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dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors by Yasser Hayek-Orduz, Dorian Armando Acevedo-Castro, Dorian Armando Acevedo-Castro, Juan Sebastián Saldarriaga Escobar, Brandon Eli Ortiz-Domínguez, María Francisca Villegas-Torres, Paola A. Caicedo, Álvaro Barrera-Ocampo, Natalie Cortes, Edison H. Osorio, Andrés Fernando González Barrios

“…Therapeutic strategies for Alzheimer’s disease (AD) often involve inhibiting acetylcholinesterase (AChE), underscoring the need for novel inhibitors with high selectivity and minimal side effects. …”
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Antibody Responses to mRNA COVID-19 Vaccine Among Healthcare Workers in Outpatient Clinics in Japan by Teruhime Otoguro, Keita Wagatsuma, Toshiharu Hino, The Society of Ambulatory and General Pediatrics of Japan, Yusuke Ichikawa, Tri Bayu Purnama, Yuyang Sun, Jiaming Li, Irina Chon, Hisami Watanabe, Reiko Saito

“…These findings provide valuable insights for developing personalized vaccination strategies and future vaccine development.…”
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Injury characteristics, mechanisms, and game circumstances in junior community-level Australian football by Indianna L. Franke, Andrea B. Mosler, Brooke E. Patterson, Kay M. Crossley, Patrick Clifton, Steven McPhail, Mark J. Scholes, Matthew G. King

“…Conclusion: The head was the most frequently reported injured body region, with approximately one in every two reported head impacts resulting in a diagnosed/suspected sports-related concussion. Injury prevention strategies that promote safety when tackling and being tackled may reduce the frequency of injury, warranting further investigation.…”
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Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question by Brandon A. Kohrt, Dristy Gurung, Ritika Singh, Sauharda Rai, Mani Neupane, Elizabeth L. Turner, Alyssa Platt, Shifeng Sun, Kamal Gautam, Nagendra P. Luitel, Mark J.D. Jordans

“…Rethinking research strategies to evaluate accuracy of diagnosis is vital to improve training, supervision and delivery of mental health services around the world.…”
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Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson DiseaseSummary by Donghu Zhou, Huaduan Zi, Xiaoxi Yang, Xiaojin Li, Yanmeng Li, Anjian Xu, Bei Zhang, Wei Zhang, Xiaojuan Ou, Jidong Jia, Jian Huang, Hong You

“…These findings provide a foundation for the development of innovative therapeutic strategies that target abnormal splicing events in a range of hereditary diseases, including Wilson disease.…”
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Aberrant Expression of JAM2 Inhibits Invasion and Migration in Lung Adenocarcinoma by Jun Chen, Yuan Cui, Zhimeng Chen, Hao Ding, Chang Li, Sheng Ju, Cheng Ding, Chun Xu, Jun Zhao, Xin Tong

“…Its downregulation in LUAD, potential role as a prognostic gene, and influence on cell migration, invasion, and inflammatory infiltration make it a valuable target for further research and development of therapeutic strategies.…”
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Real-world clinical outcome of unresectable locally advanced & de-novo metastatic pancreatic ductal adenocarcinoma: a multicentre retrospective study by Mohamed Aseafan, Ali H. Alfakeeh, Emad Tashkandi, Mervat Mahrous, Mohammed Alghamdi, Bader Alshamsan, Marwan Al-Hajeili, Safwan Bakhsh, Kanan Alshammari, Fahad A. Almugbel, Abdulhameed H. Alfagih, Ahmed Allehebi, Mohamed Montaser, Mohamed Hamdy Elsafty, Khaled Abd Elaziz Elnaghi, Ibrahim Issa, Eesa Bakshi, Sadeem AlSubaie, Bandar AlMutairi, Hoda Mokhtar, Mohamed Aboelatta, Nedal Bukhari, Ali M. Alzahrani, Tusneem Elhassan, Ali Alqahtani, Shouki Bazarbashi

“…However, both treatments reflect the persistent poor prognosis of PDAC, underscoring the need for novel therapeutic strategies. Further research is warranted to optimize treatment selection and improve survival outcomes in this population.…”
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Proteinuria and the risk of Incident atrial fibrillation according to glycemic stages: a nationwide population-based cohort study by Muhan Yeo, So-Ryoung Lee, Eue-Keun Choi, JungMin Choi, Kyung-Yeon Lee, Soonil Kwon, Hyo-Jeong Ahn, Bong-Seong Kim, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip

“…Tailoring clinical strategies to proteinuria level could potentially mitigate this risk, improving patient outcomes. …”
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Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st... by Ming Yan, Zhijie Xu, Andrew Farmer, Yu Xia, Mi Yao, Lingyan Wu, Xinmei Zhou, Liyan Han

“…Future research could develop and evaluate implementation strategies to address specific challenges and barriers to allow PCPs to make effective medication decisions for patients with multimorbidity.…”
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Perspectives of the COVID-19 pandemic and vaccination among racially and ethnically diverse gay, bisexual, and other men who have sex with men with and without HIV in the US South:... by Jake S. Waldman, Jorge Alonzo, Lilli Mann-Jackson, Sandy K. Aguilar-Palma, Manuel Garcia, Benjamin D. Smart, Scott D. Rhodes

“…Sixteen themes emerged that were categorized into five domains: trust/mistrust of politicians, healthcare professionals, and the US government (n = 4 themes); engagement in COVID-19 prevention strategies (n = 2 themes); attitudes towards COVID-19 vaccination (n = 3 themes); access to and use of health care (n = 4 themes); and impact of COVID-19 on social determinants of health and mental health (n = 3 themes). …”
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Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma by Brandon Wee Siang Phon, Shalini Sundramurthi Chelliah, Dina El-Rabie Osman, Saatheeyavaane Bhuvanendran, Ammu Kutty Radhakrishnan, Muhamad Noor Alfarizal Kamarudin

“…Conclusions: These findings reinforce the important role played by ABC transporters, particularly by ABCA13, ABCB9, and ABCB1, which could be potential targets that warrant further evaluations for alternate strategies to augment the effects of existing alkylating agents and xenobiotic drugs.…”
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Investigating the Relationship between Automatic Negative Thoughts and Experiential Avoidance with Psychological Distress and the Mediating Role of Cognitive Emotion Regulation in... by Ahmad Alipour, Afsaneh Rahimi, Shahin Shadnia, Mitra Rahimi, Peyman Erfan Talab Evini, Sayed Masoud Hosseini, Babak Mostafazadeh

“…By the clinical management of automatic negative thoughts and shifting individuals’ cognitive emotion regulation toward adaptive strategies, there is potential for a substantial reduction in suicidal ideation and attempts which can be evaluated in future clinical trials. …”
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INTERPROFESSIONAL COLLABORATION AND HEALTHCARE ORGANIZATION: an exploratory investigation into the challenges and opportunities for rehabilitation professionals. by Simone Sottana, Andrea Vianello, Matteo Tognin, Deborah Mazzarotto, Marco Ceccato, Daria Visintin, Riccardo Martignon, Francesca Magaton Rizzi, Noemi Pasquon, Lucia Savietto

“…The analysis highlighted the intricate nature of interprofessional collaboration as an ever-evolving phenomenon that necessitates the formulation of educational and organizational strategies capable of transcending existing barriers while embracing professional diversity. …”
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