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29021
Provider Preference, Logistical Challenges, or Vaccine Hesitancy? Analyzing Parental Decision-Making in School Vaccination Programs: A Qualitative Study in Sydney, Australia
Published 2025-01-01“…This study provides valuable insights into social determinants of vaccine acceptance and offers actionable strategies for improving vaccine uptake in school-based programs.…”
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29022
Predicting the effects of introducing an emergency transport system in low-income and middle-income countries: a spatial-epidemiological modelling study
Published 2024-04-01“…Alternative modelling strategies may be able to fill this gap.Methods We have developed a spatial-epidemiological model of emergency transport for life-threatening conditions. …”
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29023
Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil
Published 2025-01-01“…These findings highlight key challenges in DHI implementation, including the need for robust outreach, iterative improvements, and strategies to sustain engagement. Addressing digital access, literacy inequities, and strengthening regulations are critical for the future success and equity of DHIs in public health systems. …”
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29024
Circulating Levels of Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Schizophrenia: a systematic review and meta-analysis
Published 2025-01-01“…Future research should focus on elucidating the mechanisms underlying altered GDNF levels and exploring its implications for treatment strategies.…”
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29025
A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on Candida auris and Candida albicans
Published 2025-06-01“…., farnesol), HSL reduces several C. auris survival strategies, which may significantly influence the nature of P. aeruginosa–C. auris co-habitation. …”
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29026
Regulation of MAP2, GFAP, and calcium in the CA3 Region Following Kainic Acid Exposure to organotypic hippocampal slice culture [version 3; peer review: 2 approved]
Published 2025-01-01“…It is necessary to develop further research regarding regulation of calcium, MAP2, and GFAP at a spatial time after exposure to kainic acid and strategies to reduce damage caused by excitotoxicity.…”
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29027
Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics
Published 2024-12-01“…The reasons for this include a lack of specific therapy options, increasing antiparasitic drug resistance, a lack of control strategies, and the absence of an approved vaccine. …”
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29028
Contemporaneous Emotion Regulation Theoretical Models: A Systematic Review
Published 2022-03-01“…Discussion: There is a consensus on the use of emotion regulation strategies to adapt to environmental demands, achieve goals and increase well-being. …”
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29029
Systematic identification and quantification of factors and their interactions with age, sex, and panel wave influencing cognitive function in Korean older adults
Published 2025-02-01“…Thus, identifying these factors including their interactions with age, sex, and panel wave and conducting a systematic quantification of their influences on cognitive function are both necessary for developing efficient intervention strategies.MethodsTo identify the influencing factors and their interactions, we applied a systematic stepwise variable selection using 2,535 community-dwelling older adults who participated in the Korean Longitudinal Study of Aging from Wave 5 (2014) to Wave 8 (2020). …”
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29030
Risk Factor Analysis in Vascular Access Complications for Hemodialysis Patients
Published 2025-01-01“…<b>Conclusions</b>: These findings suggest that clinical interventions, such as stricter perioperative glycemic and blood pressure control, and personalized surgical strategies for patients with high BMI or comorbidities, could significantly reduce the incidence of vascular access complications and improve outcomes in this high-risk population.…”
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29031
Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy
Published 2025-02-01“…Objective: This study endeavors to elucidate the multifaceted roles of cancer-associated fibroblasts within the tumor microenvironment of prostate cancer, with a focus on their implications for disease prognosis and the potential for novel immunotherapeutic strategies. Methods: Leveraging advanced single-cell RNA sequencing technology, we meticulously characterized the diverse CAF subpopulations within prostate cancer samples. …”
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29032
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
Published 2024-12-01“…The study examines the possible impact of PEA on personalized medicine strategies and its potential for translation into clinical practice. …”
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29033
The Feasibility of Telephone-delivered Self-management Intervention in Multiple Sclerosis
Published 2025-01-01“…The telephone-delivered self-management intervention, delivered through educational video files and telephone calls, included evidence-based cognitive behavioral therapy and psychological strategies to assist participants. The intervention was delivered in 8 weekly sessions. …”
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29034
MUC2 expression modulates immune infiltration in colorectal cancer
Published 2025-01-01“…A deeper understanding of the interaction of cancer cells with other cells in the tumor microenvironment is crucial to devise effective therapeutic strategies. MUC2, a major component of the protective mucus layer in the gastrointestinal tract, has been implicated in CRC progression and immune response regulation.MethodIn this study, we sought to elucidate the relationship between MUC2 expression and immune infiltration within CRC using in vitro models involving two well-established cell lines, HT-29 and LS-174T. …”
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29035
Roles of core nosZ denitrifiers in enhancing denitrification activity under long-term rice straw retention
Published 2025-02-01“…The denitrification process is known to contribute to soil nitrogen (N) loss, which is strongly affected by fertilization strategies; however, the effects of distinct straw retention modes on soil denitrification activity have rarely been discriminated and the underlying mechanisms remain unclear. …”
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29036
Formation of Adaptive Trophic Niches of Euryphagous Fish Species in Response to Off-Seasonal Water Level Regulation in Hongze Lake
Published 2024-12-01“…These insights are essential for refining water management policies and developing sustainable fishery management strategies of Hongze Lake and other water-level-regulated systems.…”
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29037
Global Distribution and Projected Variations of Compound Drought‐Extreme Precipitation Events
Published 2024-07-01“…This study contributes to a better understanding of the patterns of CDEP and helps to develop more targeted risk management strategies.…”
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29038
‘If one doesn't happen, the other will’: forensic mental health service patients’ experiences of co-occurring self-harm and aggression
Published 2025-01-01“…Results Six themes were generated: self-harm and aggression as emotional regulation strategies, the consequences of witnessing harmful behaviours, relationships with others and the self, trapped within the criminal justice system, the convergence and divergence of self-harm and aggression, and moving forward as an FMHS patient. …”
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29039
Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing
Published 2024-12-01“…These findings strengthen the hypothesis for the MR-mediated mAb interaction and contribute to a deeper understanding of the MR-mAb interaction, which could affect the criticality of high-mannose containing mAbs development strategies of IgG-based molecules and improve their PK profiles.…”
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29040
Groundwater for drinking and sustainable agriculture and public health hazards of nitrate: Developmental and sustainability implications for an arid aquifer system
Published 2025-03-01“…These findings highlight the need for integrated strategies for sustainable groundwater management worldwide.…”
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