Efficacy and Safety of a Combination of Enteral and Parenteral Nutrition Support in the Postoperative Period for Patients with Gastrointestinal Cancer: A Systematic Review and Meta... by Meixiang Cai, Bo Yang, Yaping Zheng, Lei Ding

“…Background: Postoperative nutritional support in gastrointestinal cancer, including enteral nutrition (EN), parenteral nutrition (PN), and combined nutrition strategies, is vital for enhancing recovery and patient outcomes. …”
Get full text

Survey and Identification of Fusarium Head Blight Pathogens of Wheat in the Western Cape Region of South Africa by Ali Al-Hashimi, Augustine Innalegwu Daniel, Omolola Aina, Morné Du Plessis, Marshall Keyster, Ashwil Klein

“…These findings provide significant insights into the distribution of <i>Fusarium</i> species and their associated trichothecene chemotypes in the Western Cape, which is crucial for developing effective FHB management strategies and ensuring food security and safety.…”
Get full text

Reconstruction of Alzheimer’s Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient by Sijun Liu, Yuying Zhao, Xiaoying Su, Chengcheng Zhou, Peifen Yang, Qiusan Lin, Shijun Li, Hanxu Tan, Qi Wang, Changjun Wang, Qingguang Wu

“…The establishment of human-induced pluripotent stem cell (iPSC) models from sporadic Alzheimer’s disease (sAD) patients is necessary and could potentially benefit research into disease etiology and therapeutic strategies. However, the development of sAD iPSC models is still limited due to the multifactorial nature of the disease. …”
Get full text

Expression profile of Bcl‐2 family proteins in newly diagnosed multiple myeloma patients by Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Ignacio J. Cardona‐Benavides, Myriam Cuadrado, Isabel Isidro, María‐José Calasanz, Manuela Fernandez, Ramón García‐Sanz, Noemi Puig, M. Teresa Cedena, Bruno Paiva, Laura Rosiñol, Joaquín Martínez‐López, Joan Bladé, Juan J. Lahuerta, Jesús F. San Miguel, María V. Mateos, Luis A. Corchete, Norma C. Gutiérrez, GEM/PETHEMA cooperative study group

“…We shed light on the impact of these proteins on MM prognosis, which could help to consider the levels of proteins involved in apoptosis in the development of new therapeutic strategies.…”
Get full text

Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

“…Although improving TEX and enhancing effector function are promising strategies for strengthening immunotherapy, their role in the pathogenesis of TNBC remains unclear. …”
Get full text

State of the Art Compendium: Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease by Denis E O’Donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…Patients with advanced COPD and respiratory failure require a comprehensive management plan that incorporates structured end-of-life care. Management strategies, consisting of combined modern pharmacotherapy and nonpharmacotherapeutic interventions (eg, pulmonary rehabilitation and exercise training) can effectively improve symptoms, activity levels and quality of life, even in patients with severe COPD.…”
Get full text

Serum Cystatin S (CST4): A Novel Prognostic Marker for Gastric Cancer by Chao Gu, Shan Chen, Lining Huang, Chenliang Cao, Renshun Yuan, Zhongyang Kou, Weiwei Chen, Haihua Shi, Xiaodong Gu

“…Conclusion: Cystatin S is an effective biomarker for GC prognostic assessment, assisting in the evaluation of prognosis and the selection of treatment strategies for patients with GC.…”
Get full text

Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis by Nirajan Niroula, Priya Ghodasara, Nelson Marreros, Bailey Fuller, Haley Sanderson, Slim Zriba, Stew Walker, Todd K. Shury, Jeffrey M. Chen

“…Thus, effective BTB control strategies in WBNP bison are urgently needed. To this end, we aerosol challenged young bison with different doses of virulent M. bovis and observed disease-associated delayed-type hypersensitivity, gross lung and lymph node pathology and histopathology, as well as M. bovis burden in target organs, thus confirming the establishment of BTB in challenged animals. …”
Get full text

Tacrolimus- and Mycophenolate-Mediated Toxicity: Clinical Considerations and Options in Management of Post-Transplant Patients by Alan D. Kaye, Shivam S. Shah, Coplen D. Johnson, Adalyn S. De Witt, Austin S. Thomassen, Charles P. Daniel, Shahab Ahmadzadeh, Sridhar Tirumala, Kristin Nicole Bembenick, Adam M. Kaye, Sahar Shekoohi

“…Therapeutic drug monitoring (TDM) and pharmacogenomics have emerged as essential strategies for mitigating these toxicities. TDM ensures tacrolimus trough levels are maintained within a therapeutic range, minimizing the risks of nephrotoxicity and rejection. …”
Get full text

Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Cosmo Nazzareno Santoni, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

“…Our findings highlight the importance of continued surveillance. Long-term strategies for monitoring and maintaining effective immunity against SARS-CoV-2 are critical to inform the role of NPIs to effectively manage future variants with potentially higher intrinsic transmissibility and severe outcomes.…”
Get full text

Diet-microbiome covariation across three giraffe species in a close-contact zone by Elin Videvall, Brian A. Gill, Michael B. Brown, Hannah K. Hoff, Bethan L. Littleford-Colquhoun, Peter Lokeny, Paul M. Musili, Tyler R. Kartzinel

“…Moreover, striking levels of diet variation were revealed among neighboring populations of giraffe from the same species, and thus baseline knowledge of their resource-use diversity could support ongoing efforts to geographically tailor management strategies aimed at conserving local food staples under environmental change.…”
Get full text

Cross‐Sectional Imaging Modalities in Correlation to the Thrombolysis in Cerebral Infarction Score: The Next Frontier in Adjunctive Endovascular Stroke Therapy by Johannes Kaesmacher, Kilian M. Treurniet, Manon Kappelhof, Tomas Dobrocky, Johanna Ospel, Adnan Mujanovic, Jens Fiehler, Bernard Yan, Mayank Goyal, Albert J. Yoo, Bruce Campbell, Osama O. Zaidat, Jeffrey L. Saver, Nerses Sanossian, Radoslav Raychev, Yvo B. W. E. M. Roos, Urs Fischer, Charles B. L. M. Majoie, Jan Gralla, David S. Liebeskind

“…As such, the current definition of eTICI grading is only suitable to estimate the efficacy of reperfusion strategies occurring after the baseline catheter angiogram. …”
Get full text

Exploring the relationship between mental health status and life events in children and adolescents: the role of mediating factors by Jiemei Xie, Jiemei Xie, Guoqiang Cheng, Mingliang Zhou, Qisheng Liang, Qianjin Wang, Qianjin Wang, Qianjin Wang

“…These findings can inform strategies to help mitigate the emotional impact of negative life events, enhance mental health, and provide a scientific basis for developing effective interventions.…”
Get full text

Big Data Governance Challenges Arising From Data Generated by Intelligent Systems Technologies: A Systematic Literature Review by Yunusa Adamu Bena, Roliana Ibrahim, Jamilah Mahmood, Arafat Al-Dhaqm, Ahmad Alshammari, Maged Nasser, Muhammed Nura Yusuf, Matthew O. Ayemowa

“…It provides a structured roadmap for organizations to benchmark governance practices, prioritize improvements, and implement effective strategies. The model was validated through a pilot study conducted with a public higher learning institution, demonstrating its practical applicability and effectiveness in real-world scenarios. …”
Get full text

Single-Institution Experience With Nononcologic Total Femoral Replacement by Ryan Ouillette, MD, Kevin Chen, BA, Matthew Dipane, BA, Alexander Christ, MD, Edward McPherson, MD, Alexandra Stavrakis, MD

“…Clinicians should weigh potential complications when considering TFR, emphasizing patient counseling and risk mitigation strategies.…”
Get full text

HLA-G high-expressor 3’UTR markers are linked to gastric cancer development and survival by Christian Vaquero-Yuste, Ignacio Juarez, Marta Molina-Alejandre, Elisa María Molanes-López, Alberto Gutiérrez-Calvo, Adela López-García, Inmaculada Lasa, Remedios Gómez, Antonio Arnaiz-Villena, Jose Manuel Martín-Villa

“…Further elucidation of HLA-G-related pathways could lead to personalized treatment strategies and improved patient outcomes in gastric cancer.…”
Get full text

Anxiety as a mediator between symptom distress and quality of life in peritoneal dialysis patients: insights from mediation analysis and nonlinear models by Sixia Chen, Yun Wang, Sheng Feng, Mingli Shen, Fan Zhang, Kai Song, Wenwen Li, Yun- Wang

“…Future research should explore longitudinal designs and standardized intervention strategies.…”
Get full text

The value-added model of the supply chain of petrochemical industries with a sustainable development approach by ali amiri, seyed abbas heydari, vahidreza Mirabi

“…Cultural factors: Deep understanding of local culture in target countries and matching strategies and approaches with cultural values ​​and beliefs can help improve performance and interactions. …”
Get full text

The potential of fungi-bacterial biofilm, compost, and LOF compared with chemical fertilization in supporting the growth of pakcoi (Brassica rapa var chinensis) by Rosariastuti Retno, Rosada Hanifati, Sutami, Irawan Evi, Nugraha Setyo, Simamarta Rumella, Haryuni

“…These findings support climate change mitigation strategies by reducing chemical fertilizers that contribute to carbon emissions while adopting sustainable agricultural practices that utilize biofilms and organic materials to increase productivity while maintaining ecosystem health.…”
Get full text

Household transmission of SARS-CoV-2 in five US jurisdictions: Comparison of Delta and Omicron variants. by Julia M Baker, Jasmine Y Nakayama, Michelle O'Hegarty, Andrea McGowan, Richard A Teran, Stephen M Bart, Lynn E Sosa, Jessica Brockmeyer, Kayla English, Katie Mosack, Sanjib Bhattacharyya, Manjeet Khubbar, Nicole R Yerkes, Brooke Campos, Alina Paegle, John McGee, Robert Herrera, Marcia Pearlowitz, Thelonious W Williams, Hannah L Kirking, Jacqueline E Tate

“…Comparing household transmission rates by SARS-CoV-2 variant may provide relevant information about current risks and prevention strategies. This investigation aimed to estimate differences in household transmission risk comparing the SARS-CoV-2 Delta and Omicron variants using data from contact tracing and interviews conducted from November 2021 through February 2022 in five U.S. public health jurisdictions (City of Chicago, Illinois; State of Connecticut; City of Milwaukee, Wisconsin; State of Maryland; and State of Utah). …”
Get full text