Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer by Liping Luo, Juan Ji, Juan Dong, Maotao He, Wenjun Jiang, Yang Liu, Weidong Wang

“…This finding could facilitate the advancement of novel cancer treatment strategies.…”
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Detection and Phylogenetic Analysis of an Exotic Strain of Porcine Epidemic Diarrhea Virus and Its Effect on an Affected Herd Immunized Against the Endemic Strain in Thailand by Christopher James Stott, Patumporn Jermsutjarit, Pornchai Pornpanom, Hongyao Lin, Angkana Tantituvanont, Dachrit Nilubol

“…This study highlights the importance of monitoring emerging strains and provides valuable insights for enhancing preventive strategies and advancing phylogenetic research.…”
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Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancer by Wen Yin, Yanting Ao, Qian Jia, Chao Zhang, Liping Yuan, Sha Liu, Wanmeng Xiao, Gang Luo, Xiaomin Shi, Chen Xin, Maolin Chen, Muhan Lü, Zehui Yu

“…In summary, we developed a prognostic marker associated with inflammatory genes to provide new directions for subsequent studies and to help clinicians assess the prognosis of CRC patients as well as to develop personalized treatment strategies.…”
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Talking with pregnant women exposed to cannabis use after cannabis legalization: Experiences of professionals working in Québec's social and healthcare system by Karen A. Dominguez-Cancino, Rose Chabot, Yolaine Frossard de Saugy, Kristelle Alunni-Menichini, Lysiane Robidoux-Léonard, Genève Guilbert-Gauthier, Karine Bertrand, Christophe Huỳnh, Pablo Martínez, Helen-Maria Vasiliadis, Nadia L'Espérance, Victoria Massamba, Julie Loslier, José Ignacio Nazif-Munoz

“…It discusses the importance of integrating harm reduction strategies with person-centered approaches to address cannabis use. …”
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Polymorphisms in immunosuppression-related genes are associated with AML by Mingying Li, Mingying Li, Jingjing Ye, Jingjing Ye, Mengyuan Chang, Mengyuan Chang, Lei Feng, Lei Feng, Tingting Liu, Tingting Liu, Di Zhang, Di Zhang, Yuyan Wu, Yuyan Wu, Yuechan Ma, Yuechan Ma, Guangqiang Meng, Guangqiang Meng, Chunyan Ji, Chunyan Ji, Tao Sun, Tao Sun

“…Despite new immunotherapeutic strategies entering standard clinical care for various tumors, progress in AML remains poor. …”
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Quality-by-Design Principles Applied to the Establishment of a Pharmaceutical Quality Control Laboratory in a Resource-Limited Setting: The Lab Water by Sultan Suleman, Sileshi Belew, Dereje Kebebe, Markos Duguma, Henok Teshome, Gemmechu Hasen, null Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer

“…The results of routine analysis of water quality revealed that HPLC global peak area at 210 and 254 nm could serve as one of the discriminatory control strategies to evaluate the capability of water purification system to produce the desired quality of lab water; and thus, we proposed a specification limit of 5,000 mAU∗s and 5,500 mAU∗s for global peak area at 254 and 210 nm, respectively, as system suitability parameter.…”
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A multi-stage deep learning network toward multi-classification of polyps in colorectal images by Shilong Chang, Kun Yang, Yucheng Wang, Yufeng Sun, Chaoyi Qi, Wenlong Fan, Ying Zhang, Shuang Liu, Wenshan Gao, Jie Meng, Linyan Xue

“…In convolution, our approach not only demonstrates a significant improvement over existing methods by effectively emulating the step-by-step diagnostic process of endoscopists, but also promises to greatly enhance early detection and treatment strategies for CRC, ultimately improving patient outcomes.…”
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Identifying Zoonotic Parasites in Domiciled and Non‐Domiciled Dogs (Canis lupus familiaris) Within an Urban Zone of the Eastern State of Mexico by José Salcedo‐Jiménez, Yazmín Alcala‐Canto, Julio Segura‐Tinoco, Ernestina Valadez‐Moctezuma, Juan José Pérez‐Rivero

“…Implementing prevention, control and awareness strategies is crucial to reduce the spread of these parasites.…”
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Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes by Ali Tawbeh, Catherine Gondcaille, Fatima-Ezzahra Saih, Quentin Raas, Damien Loichot, Yannick Hamon, Céline Keime, Alexandre Benani, Francesca Di Cara, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

“…This dysfunction might contribute to the early neurodegenerative events in X-ALD by triggering and sustaining neuroinflammatory cascades. Therapeutic strategies that target microglial activation and secretion profiles could hold promise in managing peroxisomal disorders such as X-ALD.…”
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Fluorescence Lifetime Imaging of NAD(P)H in Patients’ Lymphocytes: Evaluation of Efficacy of Immunotherapy by Diana V. Yuzhakova, Daria A. Sachkova, Anna V. Izosimova, Konstantin S. Yashin, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev, Artem M. Mozherov, Vladislav I. Shcheslavskiy, Marina V. Shirmanova

“…Background: The wide variability in clinical responses to anti-tumor immunotherapy drives the search for personalized strategies. One of the promising approaches is drug screening using patient-derived models composed of tumor and immune cells. …”
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Building a near-infrared (NIR) soil spectral dataset and predictive machine learning models using a handheld NIR spectrophotometerZenodo by Colleen Partida, Jose Lucas Safanelli, Sadia Mannan Mitu, Mohammad Omar Faruk Murad, Yufeng Ge, Richard Ferguson, Keith Shepherd, Jonathan Sanderman

“…Two model types, Cubist and partial least squares regression (PLSR) were developed using two strategies: (1) using an average of the spectral scans across devices for each sample and, (2) using the replicate spectral scans across devices for each sample. …”
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Ironing out differences in attenuation and blooming artifact in acute stroke thrombi by Aglae Velasco Gonzalez, Dennis Görlich, Boris Buerke, Cristina Sauerland, Norbert Meier, Manfred Fobker, Ray McCarthy, Astrid Jeibmann, Walter Heindel, Andreas Faldum, Harald Kugel

“…Furthermore, these results open the possibility for future research aimed at developing pH-modulated therapeutic strategies based on the acid-base state of thrombi.…”
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Feather hydrolysate as a promising nitrogenârich fertilizer for greenhouse lettuce cultivation by Lisiane Sobucki, Rodrigo Ferraz Ramos, Elci Gubiani, Gustavo Brunetto, Douglas Rodrigo Kaiser, Daniel Joner Daroit

“…Since waste management strategies include the use of organic wastes as soil fertilizer, PL, FM, and FH were evaluated as fertilizers for lettuce in comparison to urea. …”
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Perceived barriers to reaching equity in effective access to diagnosis and treatment for women with breast cancer in Chile by Carla Campaña, Báltica Cabieses, Alexandra Obach, Francisca Vezzani

“…Theoretical sampling guided the selection of diverse participant profiles, comprising breast cancer patients, healthcare professionals and a civil society leader. The strategies for the recruitment process included social networks, civil society organizations, health professionals, and the snowball technique. …”
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Alterations of lung and gut microbiota in sodium butyrate alleviating heat stress-induced lung injury of broilers by Qiang Niu, Yiwen Lu, Meijuan Ren, Jiale Zhu, Yan Zhao, RuMeng Zhang, Xiaojun Yang, Qingzhu Sun

“…This study provides critical insights for developing dietary strategies to reduce heat stress and promote broiler health.…”
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Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors by Tanja Eichhorn, Ingrid Linsberger, Lucia Lauková, Carla Tripisciano, Birgit Fendl, René Weiss, Franz König, Gerhard Valicek, Georg Miestinger, Christoph Hörmann, Viktoria Weber

“…The timely recognition of sepsis and the prediction of its clinical course are challenging due to the complex molecular mechanisms leading to organ failure and to the heterogeneity of sepsis patients. Treatment strategies relying on a “one-fits-all” approach have failed to reduce mortality, suggesting that therapeutic targets differ between patient subgroups and highlighting the need for accurate analysis of the molecular cascades to assess the highly variable host response. …”
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Genomic insights and comparative analysis of Colletotrichum species associated with anthracnose fruit rot and crown rot of strawberry in North Carolina by Tika B. Adhikari, Norman Muzhinji, Ashley N. Philbrick, Frank J. Louws, Frank J. Louws

“…., elucidate their evolutionary history, and enhance the understanding of fungal biology and ecology, which is crucial for developing effective disease management strategies.…”
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H₂S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins by Rahib K. Islam, Erinn Donnelly, Erminia Donnarumma, Fokhrul Hossain, Jason D. Gardner, Kazi N. Islam

“…Endogenously produced hydrogen sulfide (H₂S) is critical for cardiovascular homeostasis. Therapeutic strategies aimed at increasing H₂S levels have proven cardioprotective in models of acute myocardial infarction (MI) and heart failure (HF). …”
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Curtailing the spread of COVID-19 in Nigeria using digital framework and data driven approaches by Bolanle Adefowoke Ojokoh, Benjamin S. Aribisala, Oluwafemi A. Sarumi, Tobore V. Igbe, Abimbola H. Afolayan, Arome J. Gabriel, Abiola Ezekiel Taiwo, Olatunji M. Omisore, Uchechukwu M. Chukwuocha, Olusola T. Babalola, Tolulope A. Adebayo

“…It investigated the potential impact of the use of these apps on reducing infection rates and improving public health strategies. Additionally, this study provided insights into the practical implementation of such frameworks and the challenges associated with their nationwide deployment. …”
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A systematic literature review of forecasting and predictive models for enterococci intrusion in aquatic ecosystems by Philomina Onyedikachi Peter, Edoardo Bertone, Rodney A. Stewart

“…Furthermore, it offers evidence-based recommendations for selecting appropriate models to predict ENT levels, empowering researchers and water resource managers to design more effective water quality management strategies. These insights may contribute to reducing the prevalence of waterborne diseases associated with recreational water use, ultimately promoting safer and more sustainable aquatic environments.…”
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