Survey of willingness to participate in clinical trials and influencing factors among cancer and non-cancer patients by Teck Long King, Shirin Hui Tan, Shirley Siang Ning Tan, Wei Hong Lai, Mohamad Adam Bujang, Pei Jye Voon

“…This study underscores the challenges in engaging Malaysian patients in clinical trials, particularly in Sarawak, emphasising the need for targeted strategies to raise awareness, effective communication, and enhancing public confidence in clinical trials.…”
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Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy by Dongming Li, Donghui Cao, Yangyu Zhang, Xinyi Yu, Yanhua Wu, Zhifang Jia, Jing Jiang, Xueyuan Cao

“…Targeting GLS can facilitate the implementation of individualized and combined treatment strategies.…”
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<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis by Marcello Candelli, Marta Sacco Fernandez, Cristina Triunfo, Andrea Piccioni, Veronica Ojetti, Francesco Franceschi, Giulia Pignataro

“…As global temperatures continue to rise, understanding the epidemiology of <i>V. vulnificus</i> and developing innovative therapeutic strategies are critical to mitigating its growing public health impact.…”
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The effectiveness of dance interventions on the cognitive functioning of people with dementia or cognitive impairment: A systematic review by Dauda Salihu, Surajo Kamilu Sulaiman, Umar Muhammad Bello, Osama Mohamed Elsayed Ramadan, Hadiza Yahaya, Muhammad Chutiyami

“…This study supports the use of dance as an effective non-pharmacological approach in dementia care and merits its consideration in treatment strategies and further research studies. …”
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Knowledge, attitude, and practice toward vitiligo among vitiligo patients: a mediation analysis by Hua Feng, Xiulian Xu, Shuzhen Qi, Kun Chen, Mei Ju, Xiaofang Li, Shuxian Shang

“…Given the chronic nature of vitiligo and its slow treatment response, tailored health education strategies focusing on improving knowledge and attitudes are essential for standardizing treatment and enhancing patient adherence.…”
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Estimation of Dietary Acrylamide Exposure of Ethiopian Population Through Coffee Consumption by Dhaba Mengesha, Negussie Retta, Henok Ashagrie Deribew, Markos Makiso Urugo, Paulos Getachew

“…The findings suggest that reducing acrylamide content in coffee through preventive actions and mitigation strategies is advisable to minimize potential health risks.…”
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Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer by Zhao Sicheng, Zhao Sicheng, Zhang Jingcheng, Zhang Jingcheng, Zhang Shuo, Zhang Shuo, Lou Jiaheng, Lou Jiaheng, Cai Yan, Cai Yan, Bai Xing, Bai Xing, Jiang Tao, Jiang Tao, Jiang Tao, Zhang Guangji, Zhang Guangji, Zhang Guangji

“…Finally, prognosis analysis and gene mutation analysis using TCGA-STAD data indicate an adverse prognosis associated with the key gene set in GC.ConclusionThis study provides new insights into the association between AF and GC and offers novel clues for understanding its impact on the pathogenesis and therapeutic strategies of GC.…”
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Impact of climate change over distribution and potential range of chestnut in the Iberian Peninsula by Pedro Álvarez-Álvarez, Adrián Aviñoa-Arias, Adrián Aviñoa-Arias, Emilio Díaz-Varela, José Vicente López-Bao, José Carlos Pérez-Girón

“…We highlight the need to develop mitigation strategies to facilitate chestnut resilience in the face of threats related to climate change.…”
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Is Self-Reported Physical Activity Participation Associated with Lower Health Services Utilization among Older Adults? Cross-Sectional Evidence from the Canadian Community Health S... by Koren L. Fisher, Elizabeth L. Harrison, Bruce A. Reeder, Nazmi Sari, Karen E. Chad

“…Nonleisure PA appeared to be a stronger predictor of all types of HSU, particularly in the two oldest age groups. Considering strategies that focus on reducing time spent in sedentary activities may have a positive impact on reducing the demand for health services.…”
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International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids by Ralf Jäger, Jeffery L. Heileson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio

“…The following conclusions represent the official position of the ISSN: Athletes may be at a higher risk for ω-3 PUFA insufficiency.Diets rich in ω-3 PUFA, including supplements, are effective strategies for increasing ω-3 PUFA levels.ω-3 PUFA supplementation, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been shown to enhance endurance capacity and cardiovascular function during aerobic-type exercise.ω-3 PUFA supplementation may not confer a muscle hypertrophic benefit in young adults.ω-3 PUFA supplementation in combination with resistance training may improve strength in a dose- and duration-dependent manner.ω-3 PUFA supplementation may decrease subjective measures of muscle soreness following intense exercise.ω-3 PUFA supplementation can positively affect various immune cell responses in athletic populations.Prophylactic ω-3 PUFA supplementation may offer neuroprotective benefits in athletes exposed to repeated head impacts.ω-3 PUFA supplementation is associated with improved sleep quality.ω-3 PUFA are classified as prebiotics; however, studies on the gut microbiome and gut health in athletes are currently lacking.…”
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Impact of Mobile Phone Usage on Sleep Quality Among Medical Students Across Latin America: Multicenter Cross-Sectional Study by Juan S Izquierdo-Condoy, Clara Paz, H A Nati-Castillo, Ricardo Gollini-Mihalopoulos, Telmo Raul Aveiro-Róbalo, Jhino Renson Valeriano Paucar, Sandra Erika Laura Mamami, Juan Felipe Caicedo, Valentina Loaiza-Guevara, Diana Camila Mejía, Camila Salazar-Santoliva, Melissa Villavicencio-Gomezjurado, Cougar Hall, Esteban Ortiz-Prado

“…The findings advocate for the need to address mobile phone usage to mitigate its negative implications on student health and academic performance. Strategies to enhance digital literacy and promote healthier usage habits could benefit medical education and student well-being.…”
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Transcriptional time-course analysis during ash dieback infection revealed different responses in tolerant and susceptible Fraxinus excelsior genotypes by Víctor Chano, Renata Callegari Ferrari, Tania Domínguez-Flores, Karuna Shrestha, Barbara Fussi, Hannes Seidel, Oliver Gailing, Katharina B. Budde

“…This hints to individual responses in the natural tolerance to ADB, possibly revealing diversified strategies across ash genotypes.…”
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L-Theanine Extends the Lifespan of <i>Caenorhabditis elegans</i> by Reducing the End Products of Advanced Glycosylation by Zhihang Huang, Haiming Jing, Yan Pan, Hongxia Cai, Wenjing Zhang, Jingyuan Zhu, Nan Zhang, Dan Wu, Wentao Xu, Hexiang Qiu, Huihui Bao, Guojun Li, Junyu Ning, Bo Xian, Shan Gao

“…These findings provide new insights for developing anti-aging strategies and lay the groundwork for further research on the potential benefits of L-theanine in mammals. …”
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Evaluation of the ABC pathway in patients with atrial fibrillation: A machine learning cluster analysis by Jingyang Wang, Haiyang Bian, Jiangshan Tan, Jun Zhu, Lulu Wang, Wei Xu, Lei Wei, Xuegong Zhang, Yanmin Yang

“…Conclusion: Our study suggested specific optimization strategies of risk stratification and integrated management for different groups of AF patients considering multiple clinical, genetic and socioeconomic factors.…”
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Co-occurrence of depression, anxiety and increased alcohol use during the late stage of the COVID-19 pandemic in Saskatchewan, Canada: a cross-sectional survey by Erika Dyck, James Dixon, Nazeem Muhajarine, Daniel A Adeyinka, Md Sabbir Ahmed, Ali Bukhari, Jim Clifford, Gabriela Novotna

“…Data driven interventions, for example, improving mental health and substance use treatment and counselling services, harm reduction strategies, especially targeting people living in food insecure households, are needed.…”
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Association of Myasthenia Gravis With Autoimmune Thyroid Disease: A Bidirectional Mendelian Randomization Study by Yao Wang, Ke Wang, Jing Lu, Peng Xu, Dongmei Zhang, Xinzhi Chen, Jian Wang

“…Consequently, proactive treatment strategies targeting either MG or autoimmune thyroid disorders may help mitigate the risk of comorbidities in affected patients.…”
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Repetitive Transcranial Magnetic Stimulation: Is it an Effective Treatment for Cancer Pain? by Yanyuan Du, Yaoyuan Li, Jieqing Hu, Ruiying Fang, Yuming Liu, Liu Cai, Ying Song, Susu Ma, Jin Gao, Hanyue Zhang, Baihui Li, Hongtai Xiong, Huibo Yu, Shenglei Yang, Shuduo Zhu, Honggang Zheng

“…Continued research and clinical application are expected to establish rTMS as an essential component of comprehensive cancer pain treatment strategies, significantly enhancing the overall well-being of patients with cancer.…”
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Cerebral hemiatrophy unveiled: An in-depth radiological perspective on the diagnosis and clinical implications of Dyke-Davidoff-Masson syndrome by Rakshanda Agrawal, MBBS, Vaishali Dhawan, MBBS, Pratapsingh Parihar, MBBS, Anjali Kumari, MBBS, Komal Mishra, MBBS

“…Early recognition and diagnosis allow for optimized therapeutic strategies, including seizure management with antiepileptic medications and physiotherapy for motor deficits. …”
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The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways by Ju Ang Kim, Soomin Im, Jiwon Lim, Jung Min Hong, Hye Jung Ihn, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Eui Kyun Park

“…These findings strongly suggest that DOCK5 negatively regulates osteoblast differentiation and bone regeneration through signaling pathways involving TAK1, MKK3/6, and p38, providing new insights into potential therapeutic strategies for bone regeneration.…”
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The case for development of a core outcome set (COS) and supplemental reporting guidelines for influenza vaccine challenge trial research in swine by Sheila Keay, Famke Alberts, Annette M. O’Connor, Robert Friendship, Terri O’Sullivan, Zvonimir Poljak

“…Here, we illustrate each concern using data collected tangentially during the systematic review and propose two corrective strategies, both of which have broad applicability across veterinary intervention research; (i) develop a Core Outcome Set (COS) to reduce unnecessary clinical heterogeneity in future research and (ii) encourage funders and journal editors to require submitted research protocols and manuscripts adhere to established reporting guidelines. …”
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