Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model by Sugeun Gwon, Seong-Ah Shin, Moonsu Kim, Sun Young Moon, Seyeon Choi, Minji Kim, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee

“…Current therapeutic interventions include antihistamines and steroids; however, they induce several side effects. …”
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In Vitro Antibacterial Activity of Crude Extracts of Artocarpus heterophyllus Seeds against Selected Diarrhoea-Causing Superbug Bacteria by Asio Eve, Adamu Almustapha Aliero, Doreen Nalubiri, Rasheed Omotayo Adeyemo, Saheed Adekunle Akinola, Theophilus Pius, Saphurah Nabaasa, Susan Nabukeera, Bashir Alkali, Ibrahim Ntulume

“…The results of phytochemical screening revealed the presence of tannins, flavonoids, reducing sugars, cardiac glycosides, saponins, and steroids from the prepared crude extracts. The ethanolic and hexanolic extracts had activity on multidrug-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, and methicillin-susceptible Staphylococcus aureus with the mean and standard error zone of inhibition that ranged from 8.5 ± 0.5 to 16.5 ± 0.25 mm; however, the extracts were found not to have activity on resistant E. coli and Salmonella typhimurium. …”
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Macrophage activation syndrome in a patient with systemic lupus erythematous triggered by tuberculous meningitis by Noura Alowais, Noura Zamani, Faisal Elbadawi, Hassan Ahmed, Pankhi Dutta, Aesha Sharif

“…She was immediately started on pulse doses of steroids and anti-tuberculosis medications in which significant clinical improvement was observed. …”
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Ethanolic Extract of <i>Averrhoa carambola</i> Leaf Has an Anticancer Activity on Triple-Negative Breast Cancer Cells: An In Vitro Study by Oscar F. Beas-Guzmán, Ariana Cabrera-Licona, Gustavo A. Hernández-Fuentes, Silvia G. Ceballos-Magaña, José Guzmán-Esquivel, Luis De-León-Zaragoza, Mario Ramírez-Flores, Janet Diaz-Martinez, Idalia Garza-Veloz, Margarita L. Martínez-Fierro, Iram P. Rodríguez-Sanchez, Gabriel Ceja-Espíritu, Carmen Meza-Robles, Víctor H. Cervantes-Kardasch, Iván Delgado-Enciso

“…<b>Results</b>: Phytochemical screening revealed that the ethanolic extract was rich in flavonoids, saponins, and steroids, demonstrating an antioxidant capacity of 45%. …”
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Screening of the Dichloromethane: Methanolic Extract of Centella asiatica for Antibacterial Activities against Salmonella typhi, Escherichia coli, Shigella sonnei, Bacillus subtili... by Berick Moturi Sieberi, George Isanda Omwenga, Rachael Kitondo Wambua, Judith Chemutai Samoei, Mathew Piero Ngugi

“…Phytochemical screening of the DCM-MeOH extract revealed the presence of alkaloids, flavonoids, phenolics, terpenoids, cardiac glycosides, saponins, steroids, and tannins. The present study indicates that the tested plant can be an important source of antibacterial agents and recommends that the active phytoconstituents be isolated, identified, and screened individually for activities and also subjected further for in vivo and toxicological studies.…”
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Influence of Mesalazine on Ferroptosis-Related Gene Expression in In Vitro Colorectal Cancer Culture by Joanna Słoka, Barbara Strzałka-Mrozik, Sebastian Kubica, Ilona Nowak, Celina Kruszniewska-Rajs

“…In this study, we applied the concept of drug repositioning, selecting mesalazine (MES), a non-steroidal anti-inflammatory drug (NSAID), for investigation. …”
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Characterization of an Endemic Plant Origanum grosii from Morocco: Trace Element Concentration and Antihyperglycemic Activities by H. El hassouni, M. Bouhrim, R. El hajji, M. Bnouham, A. Ziyyat, A. Romane

“…On the other hand, tannins, flavonoids, triterpenes, and steroids were the major families strongly present in this species. …”
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A Comprehensive Comparison of Clinical Presentation and Outcomes of Kidney Transplant Recipients with COVID-19 during Wave 1 versus Wave 2 at a Tertiary Care Center, India by Sanjiv Jasuja, Gaurav Sagar, Anupam Bahl, Neharita Jasuja, Rajesh Chawla, Avdhesh Bansal, Manjit. S. Kanwar, Sudha Kansal, Nikhil Modi, Athar P. Ansari, Viny Kantroo, Purnima Dhar, Chitra Chatterjee, Nitin Ghonge, Samir Tawakley, Shalini Verma

“…Strategies to modify immunosuppressants such as discontinuation of antinucleoside drugs with or without change in calcineurin inhibitors and the use of steroids were similar during both waves. Overall patient mortality was 27.5%. …”
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Efficacy and safety of non-pharmacological, pharmacological and surgical treatments for hand osteoarthritis in 2024: a systematic review by Féline P B Kroon, Margreet Kloppenburg, Ida K Haugen, Ingvild Kjeken, Nina Østerås, Anne Therese Tveter, Geir Smedslund, Daniel Huseby Bordvik, Kristine Aasness Fjeldstad, Ingrid Skaalvik

“…Concerning pharmacological interventions, there was low-certainty evidence for a moderate short-term effect of oral non-steroidal anti-inflammatory drugs (NSAIDs) on pain, high- and moderate-certainty evidence for a small short-term effect of topical NSAIDs and oral glucocorticoids on function, respectively, and low-certainty evidence that oral glucocorticoids had a small short-term effect on function. …”
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Intraoperative visualisation and treatment of salivary glands in Sjögren’s syndrome by contrast-enhanced ultrasound sialendoscopy (CEUSS): protocol for a phase I single-centre, sin... by Arjan Vissink, K Hakki Karagozoglu, Tim Forouzanfar, Henk S Brand, Derk Hendrik Jan Jager, Marco Helder, Joseph Bot, Otto Kamp, Seunghee Cha, Gary Weisman, Imke Bartelink

“…In this technique, the ducts of the salivary glands are irrigated with saline and steroids. This allows for dilatation of ductal strictures and removal of debris. …”
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Evaluation of Melongosides as Potential Inhibitors of NS2B-NS3 Activator-Protease of Dengue Virus (Serotype 2) by Using Molecular Docking and Dynamics Simulation Approach by Partha Biswas, Ommay Hany Rumi, Dhrubo Ahmed Khan, Md Nasir Ahmed, Nusratun Nahar, Rownak Jahan, Md Nazmul Hasan Zilani, Tridib K Paul, Anamul Hasan, Tohmina Afroze Bondhon, Khoshnur Jannat, Md Nazmul Hasan, Mohammed Rahmatullah

“…The present study aimed to determine, in silico, the binding energies of the steroidal saponins, melongosides, to NS2B-NS3 activator protease of DENV-2, which plays an essential role in the viral replication. …”
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In Vitro Anthelmintic Activity and Phytochemical Screening of Crude Extracts of Three Medicinal Plants against Haemonchus Contortus in Sheep at Haramaya Municipal Abattoir, Eastern... by Hassen Shamil Mumed, Dereje Regassa Nigussie, Kedir Sali Musa, Abdallahi Abdurahman Demissie

“…The study revealed the presence of secondary metabolites such as tannins, flavonoids, steroids, and terpenoids in all extracts, which are considered to be the chemical components that are responsible for the wide therapeutic activities of several medicinal plants. …”
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Anti-inflammatory effect of Plantago asiatica crude extract in rat gout arthritis model by Bingjun Qian, Jun Hu, Li Dai, Yue Zhou, Haixia Xu

“…PAE treatment significantly reversed patho- genic joint space narrowing and swelling, reversed the MSU-induced changes in inflammatory factors, and in general imparted effects very similar to those seen with colchicine (COL; known non-steroidal anti-inflammatory drug for clinical treatment of GA). …”
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Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…Phenolics, flavonoids, alkaloids, steroids, and saponins were present in the aqueous extract. …”
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Impact of topical cetylated fatty acid cream on hand osteoarthritis: a randomized, double-blind clinical trial by Sitthiphong Suwannaphisit, Nitiphoom Sinnathakorn, Pormes Suwanno, Warangkana Fongsri, Boonsin Tangtrakulwanich

“…Abstract In addition to topical non-steroidal anti-inflammatory drugs that are used in hand osteoarthritis, there are other drugs that can reduce pain in osteoarthritis, such as topical cetylated fatty acids. …”
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COVID-19 Infection Clinical Profile, Management, Outcome, and Antibody Response in Kidney Transplant Recipients: A Single Centre Experience by Sanjiv Jasuja, Gaurav Sagar, Anupam Bahl, Shalini Verma

“…The treatment options and used were steroids (100%), convalescent plasma (32.8%), ivermectin (58.2%), doxycycline (55.2%), remdesivir (34.3%), tocilizumab (10.4%), antibiotics (61.2%), anti-fungals (26.9%), low molecular weight heparin (45.3%), and oral anti-coagulants (26.9%). …”
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Effect of Sechium edule extract on blood sugar levels and pancreatic histopathology in male Rats with type II diabetes mellitus by Marti Silfia, Gusbakti Rusip, Linda Chiuma, Ade Indra Mukti, Lia Restumulia

“…The results demonstrated that Siamese pumpkin extract contains active compounds such as alkaloids, saponins, flavonoids, steroids, triterpenoids, tannins, and glycosides. Among the treatment groups, the administration of chayote extract at a dose of 42 mg/kgBW resulted in the most significant reduction in blood glucose levels compared to the lower doses. …”
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New methods of treatment for severe and moderate postoperative pain syndrome in patients with cancer by D.V. Dmytriiev, M.M. Barsa

“…Both groups received medications in accordance with multimodal analgesia protocols (paracetamol 1 g four times daily, dexketoprofen 50 mg three times daily, additional doses of non-steroidal anti-inflammatory drugs (NSAIDs) as needed) and morphine as needed at a maximum dose of 40 mg/day. …”
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Investigating the Effect of Testosterone Supplement on Heart and Muscle Damage in Rats Applied with Swimming Exercise by Ömer Kulaksız, Sefa Lök

“…Anabolic Androgenic Steroids which are a synthetic derivative of testosterone are known to be used by some sportsmen in order to improve performance. …”
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Assessing the stability of psychobiological stress reactivity during adolescence: mixed-effect modelling of cortisol responses to laboratory stressors [version 2; peer review: 2 ap... by Elizabeth Susman, Jen O'Shea, Samantha Dockray

“…It is associated with rapid development in the hypothalamus, which is central in the production of both stress and sex steroids. While patterns of stress reactivity are calibrated in early life, this time of rapid development may provide a means for these patterns to change. …”
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