Two Patients with Therapy-Resistant Pemphigus Vulgaris and Severe Underlying Disease Showing Good Response to a New IVIg Preparation by Katharina Hogrefe, Julia K. Winkler, Alexander H. Enk

“…Standard therapy with steroids often administered together with another immunosuppressant does not respond in all patients or may not be a good therapeutic option in patients with severe underlying diseases. …”
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A Rare Case of Digital Ischemia and Gangrene in ANCA-Associated Vasculitis with Review of the Literature by Richard A. Lau, Ramandeep Bains, Duminda Suraweera, Jane Ma, Emil R. Heinze, Andrew L. Wong, Philip J. Clements

“…The patient responded well to therapy including high dose steroids and cyclophosphamide, with improvement of all organs involved and had no further digital ischemia or gangrene on follow-up. …”
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A Case of Spondyloarthritis in Patient Affected by Unicentric Castleman’s Disease Effectively Managed with Surgery Resection and Tocilizumab Treatment by M. Filippini, S. Cartella, O. Bonzanini, E. Morello, A. Tincani

“…The symptoms were very severe and resistant to anti-inflammatory drugs and steroids. She had a history of hyaline-vascular unicentric Castleman’s disease (HBV, HIV, and HHV-8 negative) treated with surgery resection. …”
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Red sorghum (Sorghum bicolor) leaf sheaths as source stable pigments by Oscar Zannou, Yann Emmanuel Miassi, Kossivi Fabrice Dossa, Marcel Houngbédji, Oyeniran Bernadin Agani, Yénoukounmè E. Kpoclou, D. Sylvain Dabadé, Midimahu Vahid Aïssi, Ilkay Koca, Adéchola P. P. Kayodé, Charis M. Galanakis

“…Anthocyanidins (luteolinidin, apigeninidin, apigeninidin-flavene dimer, apigeninidin-7-o-methylflavene dimer and 7-o-methylapigeninidin) as well as other flavonoids, phenolic acids, alkaloids, saponins, steroids and tannins have been reported as dominant phytochemicals in the leaf sheaths of red sorghum. …”
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Ocular Rosacea Causing Corneal Melt in an African American Patient and a Hispanic Patient by Joanna S. Saade, Bachir Abiad, Jonathan Jan, Dana Saadeh, James P. McCulley, Jeremy Bartley

“…The patient did well 4 weeks after starting antibacterial, oral steroids, and rosacea treatment. Discussion. Ocular rosacea can present in Hispanic and African American patients with severe manifestations such as corneal perforation.…”
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Phytochemicals, Heavy Metals, and Antioxidant Vitamins Assessment in Tomatoes (Solanum lycopersicum) Cultivated Near Cement Company Firm of Sokoto, Nigeria by Kabiru Sirajo, Zulkallaini Shehu, Anas Bello, Ibrahim Mas’ud, Kabiru Muhammad Nata’ala

“…The study confirmed the presence of flavonoids, saponins, alkaloids tannins, steroids, and volatile oils. The heavy metals detected (Cu, Zn, Cd and Cr) were found below the WHO safe limits guidelines apart from Cr which exceed WHO safe limit guidelines. …”
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Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two ca... by Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu

“…Splenectomy and thrombopoietin receptor agonists are recommended for patients who do not respond to steroids or immunosuppressive treatments. Chronic thromboembolic pulmonary hypertension is a rare disease that results from a persistent, organized thromboembolic obstruction of the pulmonary arteries due to an incompletely resolved pulmonary embolism.Case presentationsWe report two cases of chronic thromboembolic pulmonary hypertension induced by a thrombotic mechanism after treatment with splenectomy and Eltrombopag, a thrombopoietin receptor agonist, for refractory primary immune thrombocytopenia. …”
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A Rare Presentation of Checkpoint Inhibitor Induced Distal RTA by Andrew V. Doodnauth, Miriam M. Klar, Zohra R. Malik, Krunal H. Patel, Samy I. McFarlane

“…This report presents a case of a 68-year-old woman with a known history of metastatic melanoma undergoing treatment with ipilimumab+nivolumab, who developed distal renal tubular acidosis requiring stress dose steroids and sodium bicarbonate for treatment. We describe the clinical characteristics, potential mechanisms, and management of this case, highlighting the need among clinicians utilizing immune check inhibitors to be aware of this immune-related disease entity.…”
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Perfusion Imaging in Autoimmune Encephalitis by Deepak Vallabhaneni, Muhammad Atif Naveed, Rajiv Mangla, Awss Zidan, Rashi I. Mehta

“…Following treatment failure with acyclovir, antibiotics, and steroids, the patient was found to be positive for GAD65 antibodies and diagnosed with autoimmune encephalitis. …”
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Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis by Amit Frenkel, Aviel Roy-Shapira, Brotfain Evgeni, Koyfman Leonid, Abraham Borer, Moti Klein

“…Initially, he responded to steroids and antihistamines, but several attempts to withdraw treatment resulted in recurrence. …”
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Aspergillus fumigatus Endophthalmitis with Necrotizing Scleritis following Pars Plana Vitrectomy by Anna M. Gruener, Felicity Allen, Miles R. Stanford, Elizabeth M. Graham

“…He was initially treated with systemic steroids for surgically induced necrotizing scleritis following routine pars plana vitrectomy. …”
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Elevated Troponin Serum Levels in Adult Onset Still’s Disease by Carlo Umberto Manzini, Lucio Brugioni, Michele Colaci, Maurizio Tognetti, Amelia Spinella, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…The timely treatment with steroids (3 cases) or ibuprofen (1 case) leads to the remission of clinicoserological manifestations within few weeks. …”
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Long-Term Followup of Adolescent and Young Adult Females with Hypergonadotropic Hypogonadism by Tsimaris Pantelis, Vrachnis Nikolaos, Iliodromiti Zoe, Deligeoroglou Efthymios

“…The condition characterized by elevated gonadotrophins (gonadotropins elevated into the menopausal range), low sex steroids, and menstrual disorders was previously termed Premature Ovarian Failure (POF). …”
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Sclerosus and atrophic genital Lichen or vulvar craurosis. About a case by Graciela Caridad Cabrera Acea, Julia M. Hernández Mompié, Cynthia Gómez Cabrera

“…It was treated with local high potency steroids, conjugated estrogens and psychological support. …”
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Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading as Elusive Sepsis by Sumon Roy, Vinay P. Goswamy, Kirolos N. Barssoum, Devesh Rai

“…Vancomycin was switched to Linezolid and she improved on high dose steroids. The persistent fevers throughout this hospital course were thought to be an elusive endocarditis before DRESS syndrome fully manifested. …”
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The possibility of effective using the conservative and the minimally invasive treatment methods at various stages of the Dupuytren disease by Ekaterina K. Ovchinnikova, Sergey I. Gilfanov

“…Among them there are the combined use of conservative methods, the radiation therapy, the injections of collagenase and steroids, the use of immunodepressive medicines and the needle aponeurotomy. …”
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Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise by Hassam Ali, Rahul Pamarthy, Nayab Ahsan, null WashmaAwan, Shiza Sarfraz

“…It responds inconsistently to steroids, but plasma exchange and immunosuppressive therapies have shown promising results. …”
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Assessment of the impact of COVID-19 on the hearing organ by Jan Piotrowski, Bianka Nowińska, Izabela Hądzlik

“…Treatment options include administration of steroids and intratympanic injections of triamcinolone. …”
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Penile Livedoid Vasculopathy: First Reported Case by Ahmad Hallak, William Bennett, Mohammed Adib Tanbir, Supriya R. Donthamsetty, Bethaney Vincent

“…His penile ulcer continued to enlarge despite steroids and antibiotics. Due to diagnostic uncertainty, a biopsy was performed which revealed hyaline thrombi within the lumens of small vessels within the upper to mid dermis, fibrinoid material in the walls of these blood vessels and within the perivascular stroma with overlying and adjacent epidermal spongiosis, and mild perivascular lymphocytic infiltrate with a few scattered neutrophils most consistent with livedoid vasculitis. …”
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Targeting Drug Delivery to the Lungs by Inhalation by C. O'Callaghan

“…For example, ephidrine for nasal decongestion, beta-2 agonists for bronchodilatation, and inhaled steroids to suppress the inflammation seen in asthmatic airways. …”
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