The Role of Cytokines in Nephrotic Syndrome by Elham Ahmadian, Yalda Rahbar Saadat, Elaheh Dalir Abdolahinia, Milad Bastami, Mohammadali M. Shoja, Sepideh Zununi Vahed, Mohammadreza Ardalan

“…Glucocorticoids are the primary therapy for INS; however, steroid-resistant NS (SRNS) patients are at a higher risk of drug-induced side effects and harbor poor prognosis. …”
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Infliximab Salvage Therapy after Cyclosporine in an Acute Flare of Chronic Ulcerative Colitis by ECS Lam, RJ Bailey

“…Although infliximab (Remicade, Schering Canada Inc, Quebec) therapy has been well studied in steroid refractory Crohn’s disease, its use remains controversial in chronic ulcerative colitis. …”
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Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study by Ivan Taietti, Federico Zini, Emilio Amleto Conti, Enrica Cristini, Irene Borzani, Giulia Ramponi, Claudia Bracaglia, Raffaele Pecoraro, Riccardo Papa, Jessica Tibaldi, Serena Pastore, Gabriele Simonini, Marco Cattalini, Antonella Meini, Achille Marino, Stefano Lanni, Francesca Minoia, Giovanni Filocamo

“…Prospective large sample studies are required to better understand the impact of steroid exposure and its complex interplay with other potential contributing factors.…”
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Krebs von den Lungen-6 surveillance in immune checkpoint inhibitor-induced pneumonitis by Isamu Okamoto, Kazuya Tsubouchi, Ryosuke Matsukane, Shoji Nakamura, Haruna Minami, Yasuto Yoneshima, Kojiro Hata, Sai Yasukochi, Kimitaka Suetsugu, Takeshi Hirota

“…After irAE treatment, KL-6 levels in steroid-responsive patients remained unchanged; however, steroid-unresponsive patients had a significant increase in KL-6 levels at 1 month (1078 U/mL, p=0.031) compared with at irAE onset (678.0 U/mL). …”
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Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency by Anna Roppelt, Ulyana Markina, Irina Beloglazova, Irina Beloglazova, Vasily Parshin, Dmitry Kanner, Dmitry Pershin, Mariia Fadeeva, Elena Raykina, Maxim Aleksenko, Alexander Karaulov, Mariana Lysenko, Mariana Lysenko, Daria Fomina, Daria Fomina, Daria Fomina

“…The patient has been receiving systemic steroid treatment for decades, which has resulted in hormone dependence as well as therapy-related adverse side effects. …”
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Peroxisome Proliferator-Activated Receptor-𝛾 Is a Potent Target for Prevention and Treatment in Human Prostate and Testicular Cancer by Masahide Matsuyama, Rikio Yoshimura

“…Peroxisome proliferator-activated receptor-𝛾 (PPAR)-𝛾 is a ligand-activated transcriptional factor belonging to steroid receptor superfamily. PPAR-𝛾 plays a role in both adipocyte differentiation and tumorigenesis. …”
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Solid Lipid Nanoparticles Based on L-Cysteine for Progesterone Intravaginal Delivery by Roberta Cassano, Sonia Trombino

“…For this reason, a material capable of ensuring the permanence of the formulation in the administration site for the time needed to guarantee the transmucosal absorption of the steroid was synthetized in order to reduce the number of administrations and to ensure an effective concentration of drug at the site of action. …”
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Immunosuppressive therapy of patients with pemphigus with ineffectiveness of systemic corticosteroids by Vadim V. Chikin, Arfenya E. Karamova

“…As a result of the analysis, it was shown that case reports and non-compatarive studies demonstrate the effectiveness and steroid-sparing effect of azathioprine, dapsone, methotrexate, mycophenolate mofetil, cyclosporine and cyclophosphamide in the treatment of patients with pemphigus vulgaris. …”
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Immune-Mediated Neutropenia and Thrombocytopenia in a Patient with Ulcerative Colitis: An Unusual Hematological Association with IBD by Young-In Kim, Aaron Brzezinski, Joseph Brandwein, Jeffrey P Baker

“…The patient was treated with high-dose steroid, intravenous gamma-globulin and eventually splenectomy. …”
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Adalimumab (TNFα Inhibitor) Therapy Exacerbates IgA Glomerulonephritis Acute Renal Injury and Induces Lupus Autoantibodies in a Psoriasis Patient by S. S. Wei, R. Sinniah

“…He made a remarkable recovery after adalimumab cessation and steroid treatment. To our knowledge, this is a unique case of a psoriasis patient presenting with seropositive lupus markers without classical lupus nephritis renal failure and had renal biopsy proven IgA glomerulonephritis after receiving adalimumab.…”
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Kikuchi-Fujimoto Disease: A Case Report and Literature Review by Vikrant Veer, Albert Lim, Wolfgang Issing

“…This condition is mainly self-limiting; hence, management is limited to supportive care. Steroid therapy could be used in severe cases. KFD is relatively unknown in the UK and this case report aims to highlight its occurrence in our population.…”
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Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female by Hassan Riad, Hamda Al Ansari, Khaled Mansour, Haya Al Mannai, Hussein Al Sada, Samya Abu Shaikha, Sharifa Al Dosari

“…Pruritus was partially controlled by topical potent steroid and the case was resolved spontaneously after eight months.…”
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Melkersson-Rosenthal Syndrome: A Rare Cause of Recurrent Facial Nerve Palsy and Acute Respiratory Distress Syndrome by Behiye Deniz Kosovali, Asiye Yavuz, Fatma Irem Yesiler, Mustafa Kemal Bayar

“…After weaning from ventilatory support, peripheral facial paralysis was diagnosed and steroid treatment was added to her therapy. On dermatologic examination, oedema on her face, pustular lesions on her skin, and fissure on her tongue were detected. …”
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Inhibition of the production of mediators of inflammation by corticosteroids is a glucocorticoid receptor-mediated process by G. S. Madretsma, A. P. M. van Dijk, C. J. A. M. Tak, J. H. P. Wilson, F. J. Zijlstra

“…MNC were incubated with DEX and LPS or A23187 in the absence or presence of RU486, a potent steroid antagonist. DEX caused a concentration dependent inhibition of TNF-∝, IL-6 and PGE2 production but had no effect on LTB4 production. …”
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PD-1 Checkpoint Blockade in Patients for Acute Myeloid Leukemia after HSCT Relapse Resulted in Severe GVHD and sHLH by Zhi zhuo Du, Mi Zhou, Jing Ling, Lan Cao, Lingjun Kong, Shengqin Cheng, Peifang Xiao, Shaoyan Hu

“…Treatment with MP does not alleviate symptoms because of steroid resistance. Hyperbilirubinemia, rash with blisters, and watery diarrhea showed severe aGVHD. …”
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Chickenpox pneumonia. Case presentation. Dora Ngiza hospital, Port Elizabeth, South Africa. by Gilberto Serrano Ocaña, Juan Carlos Ortiz Sablon, Ilen Ochoa Tamayo

“…The deterioration of the cell-mediated immunity caused by coexisting diseases, HIV infection, cancer, hemato-oncology illnesses, steroid use, as well as advanced age, smoking, chronic obstructive pulmonary disease and hemorrhagic nature of the Skin lesions, are risk factors for developing Varicella-Zoster pneumonia. …”
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Antiproteinase 3 Positive Eosinophilic Granulomatosis with Polyangiitis Presenting with Heart Failure and Intraventricular Thrombosis by Dan Zhu, Yiming Luo, Xiangyuan Liu, Lingyun Zu

“…Interestingly, the thrombus was resolved rapidly with steroid and cyclophosphamide in the setting of interrupted anticoagulation. …”
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Successful Treatment of Genitofemoral Neuralgia Using Ultrasound Guided Injection: A Case Report and Short Review of Literature by Harsha Shanthanna

“…As a therapeutic procedure, it was injected with local anesthetic and steroid using ultrasound guidance. The initial injection led to pain relief of 3 months. …”
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Dengue hemorhagic fever associated hemophagocytc lymphohistiocytosis in primigravida: A case report by Pyrus Bhellum, Rakesh Kumar, Rishabh Bora, Bharat Kumar

“…The patient recovered successfully after initiation of intravenous steroids. Oral steroids were subsequently tapered over an next eight-week period, leading to a successful recovery. …”
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Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult by Tommy L. H. Chan, Ana M. Cartagena, Anne Marie Bombassaro, Seyed M. Hosseini-Moghaddam

“…However, cerebellar symptoms did not improve until a tapering course of steroid therapy was initiated.…”
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