Methods of saponin purification from Quillaja sp. for vaccine adjuvant production by Victor Morais, Norma Suarez, Fernando Silveira

“…Saponins are natural glycosides found in many plant species; they have a hydrophobic region, consisting of a steroid or triterpenoid skeleton called an aglycone, and a hydrophilic region, consisting of sugar chains attached to the aglycone through ether or ester linkages. …”
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Oral Tuberculosis: A Rare Manifestation of Disseminated Disease in a Patient with Dermatomyositis on Chronic Corticosteroids by Dina Khateeb, Mohleen Kang, Eugenio Capitle, Mirela Feurdean

“…We present a case of a patient with dermatomyositis on chronic steroid therapy, who presented with tuberculosis involving the tongue as the only clinical manifestation of disseminated disease. …”
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Paroxysmal Amnesia Attacks due to Hashimoto’s Encephalopathy by Pelin Nar Senol, Aylin Bican Demir, Ibrahim Bora, Mustafa Bakar

“…Hashimoto’s encephalopathy is a rare disease which is thought to be autoimmune and steroid responsive. The syndrome is characterized by cognitive impairment, encephalopathy, psychiatric symptoms, and seizures associated with increased level of anti-thyroid antibodies. …”
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Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay by Or Steg Saban, Shannon M. Vandriel, Syeda Aiman Fatima, Celine Bourdon, Amrita Mundh, Vicky L. Ng, Simon C. Ling, Robert H.J. Bandsma, Binita M. Kamath

“…Mixed effect models assessed the impact of time and daily steroid exposure on z-scores. Kaplan-Meier survival methods were used to estimate the cumulative incidence of new-onset growth impairments. …”
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Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

“…The differential metabolites were primarily enriched in the steroid hormone biosynthesis, bile secretion and ovarian steroidogenesis, according to KEGG analysis. …”
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Severe Corticosteroid-Induced Ocular Hypertension Requiring Bilateral Trabeculectomies in a Patient with Takayasu’s Arteritis by Anna Maria Gruener, Pranev Sharma, Sally Ameen, Faisal Ahmed

“…The systemic side effects of corticosteroids are well known, yet steroid-induced OHT and glaucoma remain silent causes of ocular morbidity. …”
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Synchronous Occurrence of Collagenous and Pseudomembranous Colitis by Z Vesoulis, G Lozanski, T Loiudice

“…The patient partially responded to a three-week regimen of metronidazole, and symptoms resolved completely with subsequent steroid therapy. At follow-up endoscopy four months later, colon biopsies demonstrated persistence of subepithelial collagen but no pseudomembranes. …”
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DNA methylation, histone acetylation in the regulation of memory and its modulation during aging by Padmanabh Singh, Vijay Paramanik

“…These epigenetic modifications, in turn, are regulated by physiology and metabolism. Steroid hormone estrogen and metabolites such as S-adenosyl methionine and acetyl CoA directly impact DNA and histones’ methylation and acetylation levels. …”
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Mucormycosis in COVID-19 Patients – A Case Series from a Dental College in South India by Annapoorani Sevagaperumal, A. Christy Winnifred, T. Jones R. Deva Thambi

“…COVID-19 infection results in an immunocompromised state due to the steroid therapy administered to patients and the infection itself. …”
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The Future of Asthma Treatment by Louis-Philippe Boulet

“…In the past few years, significant progress has been made in the treatment of asthma with the development of bronchodilators with longer durations of action, more concentrated inhaled steroid formulations and new modes of administering antiasthma medication. …”
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Rituximab in Refractory Myasthenia Gravis – Challenges and Lessons Learnt by Karthika A Valaparambil, Soumya Sundaram, Sruthi S Nair

“…Sustained improvement at 12 months was seen in seven patients and steroid dose could be reduced in them. Four worsened on therapy (including one death following prolonged ventilation and septicemia). …”
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IgG4 Cholangiopathy by Yoh Zen, Yasuni Nakanuma

“…IgG4-cholangiopathy should be diagnosed based on serological examinations including serum IgG4 concentrations, radiological features, and histological evidence of IgG4+ plasma cell infiltration. Steroid therapy is very effective even at disease relapse. …”
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Updates in Reproduction Coming from the Endocannabinoid System by Rosaria Meccariello, Natalia Battista, Heather B. Bradshaw, Haibin Wang

“…The tone of these lipid mediators—deeply modulated by the activity of biosynthetic and hydrolyzing machineries—regulates reproductive functions from gonadotropin discharge and steroid biosynthesis to the formation of high quality gametes and successful pregnancy. …”
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Medicinal Effect, In Silico Bioactivity Prediction, and Pharmaceutical Formulation of Ageratum conyzoides L.: A Review by Jasvidianto C. Kotta, Agatha B. S. Lestari, Damiana S. Candrasari, Maywan Hariono

“…The essential oil contains phytochemicals such as phenol, phenolic ester, and coumarin, whereas many compounds can been identified in the whole part such as terpenoid, steroid, chromene, pyrrolizidine alkaloid, and flavonoid. …”
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Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy by Mojirayo A. Sarumi, James W. Hole, Robert B. Gherman

“…At 36 weeks’ gestation, a previously healthy 23-year-old gravida with fetal intrauterine growth restriction was admitted to the hospital for steroid administration. Twenty-six hours after the first dose of betamethasone, a maternal bradycardia was initially noted and eventually nadired at 41 beats per minute. …”
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TINU: A Multisystemic Inflammatory Disorder—Case Report and Literature Review by Juan Montejo-Hernández, Jorge Rico-Fontalvo, Jose Cabrales, Shuchi Anand, María Cristina Martínez-Ávila, Claudia Duran-Merino, Luis Arias-Restrepo, Camilo Andrés Gómez Duran

“…Treatment is indicated in patients with progressive renal insufficiency, consisting of steroid therapy. Most patients recover kidney function. …”
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Effect of Estradiol-17β Injection on Gonad Development of White Shrimp (Litopenaeus vannamei) by . Tarsim, M. Zairin Junior, E. Riani

“…The occurrence of vertebrate-type steroid hormones in crustaceans have been reported, however, their physiological role are not sufficiently understood. …”
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Rumen-Degradable Starch Improves Rumen Fermentation, Function, and Growth Performance by Altering Bacteria and Its Metabolome in Sheep Fed Alfalfa Hay or Silage by Wenliang Guo, Meila Na, Shuwei Liu, Kenan Li, Haidong Du, Jing Zhang, Renhua Na

“…The metabolomics analysis showed that feeding AS upregulated the rumen tryptophan metabolism and steroid hormone biosynthesis, while the purine metabolism, linoleic acid metabolism, and amino acid biosynthesis were downregulated. …”
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Integrated metabolome and transcriptome analysis reveals key genes and pathways associated with egg yolk percentage in chicken by Wen Li, Yuxing Luo, Shoujia Zhu, Mengyuan Wang, Xuli Zhao, Zhonghua Ning

“…Metabolic pathway enrichment revealed that steroid hormone biosynthesis, glycerophospholipid metabolism, and betaine metabolism were predominant in the liver; pyruvate, taurine, and hypotaurine metabolism in the ovary; and phenylalanine metabolism in the magnum. …”
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The use of different 17β-estradiol hormone doses and water temperatures to control cannibalism in catfish Clarias gariepinus seed by Hylda Khairah Putri, Muhammad Zairin Jr., Odang Carman, Iis Diatin

“…Testosterone is a maternal steroid hormone that is transferred directly by the parent to the egg. …”
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