Lymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs by Yangkang Zheng, Lin Cong, Li Zhao, Pengyu Wang, Lianping Xing, Junling Liu, Hao Xu, Ning Li, Yongjian Zhao, Luying Yuan, Qi Shi, Xueqing Sun, Qianqian Liang, YongJun Wang

“…Moreover, unblocked lymphatic drainage decreases neutrophils and increases M2-type macrophages of the hematoma niche to support osteoblast (OB) survival and bone marrow-derived mesenchymal stem cell (BMSC) proliferation via transporting damage-associated molecular patterns (DAMPs) in male rats. …”
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An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…Although the patient underwent allogenic hematopoietic stem cell transplantation, she died of viral encephalomyelitis at 7 months after diagnosis of t-MN. …”
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Nestin Forms a Flexible Cytoskeleton by Means of a Huge Tail Domain That Is Reversibly Stretched and Contracted by Weak Forces by Ayana Yamagishi, Rina Tokuoka, Kazuki Imai, Mei Mizusawa, Moe Susaki, Koki Uchida, Saku T. Kijima, Akira Nagasaki, Daijiro Takeshita, Chiaki Yoshikawa, Taro Q. P. Uyeda, Chikashi Nakamura

“…Nestin is a type VI intermediate filament protein and a well-known neural stem cell marker. It is also expressed in high-grade cancer cells, forming copolymerized filaments with vimentin. …”
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Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice by Olga Astakhova, Anna Ivanova, Ilia Komoltsev, Natalia Gulyaeva, Grigori Enikolopov, Alexander Lazutkin

“…Besides inducing neurodegeneration, TBI alters stem cell activity and neurogenesis within primary neurogenic niches. …”
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Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation by Wen-Cheng Chung, Wei Wang, Lavanya Challagundla, Charles D. Moore, Sean E. Egan, Keli Xu

“…Here we report that deletion of Jagged1 in the mammary epithelium of virgin mice led to expansion of the mammary stem cell (MaSC) compartment and defective luminal differentiation associated with decreased expression of the progesterone receptor (PR). …”
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Preparation and Evaluation of Gelatin-Chitosan-Nanobioglass 3D Porous Scaffold for Bone Tissue Engineering by Kanchan Maji, Sudip Dasgupta, Krishna Pramanik, Akalabya Bissoyi

“…GCB 30 scaffold was shown to be noncytotoxic and supported mesenchymal stem cell attachment, proliferation, and differentiation as indicated by MTT assay and RUNX-2 expression. …”
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Macular Changes in a Mucopolysaccharidosis Type I Patient with Earlier Systemic Therapies by Augusto Magalhães, Ana Maria Cunha, Rodrigo Vilares-Morgado, Elisa Leão-Teles, Esmeralda Rodrigues, Manuel Falcão, Ângela Carneiro, Jorge Breda, Fernando Falcão-Reis

“…To describe retinal findings in a patient with mucopolysaccharidosis type I (MPS I) that underwent an early treatment with hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT). …”
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Aggressive Disease Course of Multiple Myeloma with Concomitant ALK-Negative Anaplastic Large Cell Lymphoma: A Case Report with an Unusual Presentation by Michela Staderini, Lara Mannelli, Elisabetta Antonioli, Benedetta Puccini, Valentina Berti, Francesco Mungai, Federica Vergoni, Valentina Carrai, Luigi Rigacci, Alberto Bosi

“…The therapeutic program initially included chemotherapy (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone; CHOEP), radiotherapy on the leg, bortezomib, and then consolidation with autologous hematopoietic stem cell transplantation. Despite being on bortezomib treatment and waiting for transplantation, the patient experienced an early myeloma progression that turned out to be refractory to second-line lenalidomide-based treatment. …”
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Deep Learning for Predicting Spheroid Viability: Novel Convolutional Neural Network Model for Automating Quality Control for Three-Dimensional Bioprinting by Zyva A. Sheikh, Oliver Clarke, Amatullah Mir, Narutoshi Hibino

“…A comprehensive dataset of mouse mesenchymal stem cell (mMSC) spheroids of varying sizes with corresponding viability percentages, which was obtained through CCK-8 assays, was established and used to train and validate the model. …”
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Assessing Donor Site Morbidity and Impact on Quality of Life in Free Flap Microsurgery: An Overview by Florin-Vlad Hodea, Cristian-Sorin Hariga, Eliza-Maria Bordeanu-Diaconescu, Andrei Cretu, Catalina-Stefania Dumitru, Vladut-Alin Ratoiu, Ioan Lascar, Andreea Grosu-Bularda

“…Furthermore, the integration of regenerative medicine strategies, such as stem cell therapy and fat grafting, and technological innovations, including virtual reality rehabilitation and biofeedback devices, has shown promise in enhancing recovery and minimizing long-term complications. …”
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Large-scale manufacturing and characterization of CMV-CD19CAR T cells by Stephen J Forman, Xiuli Wang, Ryan Urak, Miriam Walter, Min Guan, Tianxu Han, Vibhuti Vyas, Sheng-Hsuan Chien, Brenna Gittins, Mary C Clark, Sally Mokhtari, Angelo Cardoso, Don J Diamond, John Zaia, Ryotaro Nakamura

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Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis by Maria Papathanasiou, Aiste‐Monika Jakstaite, Sara Oubari, Johannes Siebermair, Reza Wakili, Julia Hoffmann, Alexander Carpinteiro, Tim Hagenacker, Andreas Thimm, Christoph Rischpler, Lukas Kessler, Tienush Rassaf, Peter Luedike

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Steroid hormone-induced wingless ligands tune female intestinal size in Drosophila by Lisa Zipper, Bernat Corominas-Murtra, Tobias Reiff

“…Mating increases production of the steroid hormone Ecdysone released by the Drosophila ovaries that stimulates intestinal stem cell (ISC) divisions. Here, we uncover the transcription factor crooked legs (crol) as an intraepithelial coordinator of Ecdysone-induced ISC mitosis. …”
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Swept Source Optical Coherence Tomography Angiography for Contact Lens-Related Corneal Vascularization by Marcus Ang, Yijun Cai, Anna C. S. Tan

“…This early clinical study suggests that the swept-source OCTA used may be useful for examining corneal vascularization, which may have potential for clinical applications such as detecting early limbal stem cell damage.…”
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Association of co-existing vitamin B6 and B12 deficiency with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome: a case report by Stephan Hu, Sharon Brown-Kunin, Paul Martin, Yujie Wang

“…He underwent an autologous stem cell transplant and has had improvement in his symptoms. …”
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Development of a spontaneous model of renal interstitial fibrosis in NOD/SCID mice: Aging-induced pathogenesis. by Lihua Qiu, Zhaoxia Ma, Jinyan Li, Zhen Wu, Longmei Dai, Ruimin Long, Linlin Hu, Jianxiu Sun, Min Hu, Yanjiao Li

“…Implanted allogeneic or xenogeneic cells are cleared by the immune system when stem cell therapy is applied in nonimmunodeficient animal fibrosis models, affecting the effect of the intervention and making it difficult to demonstrate the survival, proliferation, differentiation, or secretion of the delivered autologous human-derived cells. …”
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Clinical manifestation and laboratory data of illicit drugs versus other substances intoxication in children by Leila Barati, Mohammadali Vakili, Omid Mehrpour, Mehrdad Teimoorian

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CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Ugo Testa, Simona Sica, Elvira Pelosi, Germana Castelli, Giuseppe Leone

“…For B-ALL patients who relapse early after allo-HSCT or those with insufficient T-cell numbers for an autologous approach, using T cells from the original stem cell donor offers the opportunity for the successful generation of CAR-T cells and for an effective therapeutic approach. …”
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一例重型斑驳病患者的KIT基因突变检测 by 邓伟平, 陈敏华, 戴少霞

“…该突变位于KIT基因编码蛋白的细胞外配体结 合区域，第287位的缬氨酸突变为谷氨酸，可能导致了与249位谷氨酸相排斥，破坏了D3结构域中βD 和βD/βE稳定性，最 终影响SCF（stem cell factor）的结合功能。【结论】KIT基因的新生突变可能是引起本重型斑驳病患者发病的原因。…”
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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

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