Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes by Juan P. Cata, Claudius Conrad, Katy Rezvani

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Optimization of a micro-scale air–liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2 by Chandani Sen, Tammy M. Rickabaugh, Arjit Vijey Jeyachandran, Constance Yuen, Maisam Ghannam, Abdo Durra, Adam Aziz, Kristen Castillo, Gustavo Garcia, Arunima Purkayastha, Brandon Han, Felix W. Boulton, Eugene Chekler, Robert Garces, Karen C. Wolff, Laura Riva, Melanie G. Kirkpatrick, Amal Gebara-Lamb, Case W. McNamara, Ulrich A. K. Betz, Vaithilingaraja Arumugaswami, Robert Damoiseaux, Brigitte N. Gomperts

“…To date, a few primary human stem cell-based models of the proximal airway have been reported for drug discovery but scaling them up to a higher throughput platform remains a significant challenge. …”
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Integrin α8 is a useful cell surface marker of alveolar lipofibroblasts by Atsuki Fukada, Yasunori Enomoto, Ryo Horiguchi, Yoichiro Aoshima, Shiori Meguro, Hideya Kawasaki, Isao Kosugi, Tomoyuki Fujisawa, Noriyuki Enomoto, Naoki Inui, Takafumi Suda, Toshihide Iwashita

“…We analyzed their characteristics, including lipid content, transcriptome profiles, and alveolar stem cell niche capacity. ITGA8+ fibroblasts showed higher positivity of intracellular lipid droplets compared to SCA-1+ fibroblasts (91.0 ± 1.5% vs. 5.0 ± 0.5% in LipidTOX staining; 91.3 ± 1.4% vs. 7.1 ± 1.7% in Oil Red O staining). …”
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New Insight for the Diagnosis of Gastrointestinal Acute Graft-versus-Host Disease by Florent Malard, Mohamad Mohty

“…Allogeneic stem cell transplantation (allo-SCT) is a curative therapy for different life-threatening malignant and nonmalignant hematologic disorders. …”
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Novel insights into mechanisms and therapeutics for presbycusis by Xiaoying Lin, Yiyuan Xu, Chunmei Fan, Guanbin Zhang

“…Building upon these discussions, promising interventions like gene therapy and stem cell (SC) therapy are proposed for their potential value in restoring cochlear function; thus aiming to pave new avenues for prevention and cure of presbycusis.…”
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Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review by Sumit Bharti, Deepak Bhasin, Gautam Goyal, Priya Sharma

“…It is well known that immunodeficiency after radiotherapy, chemotherapy, or haematopoietic stem cell transplantation impairs the antitumour activity of the innate and adaptive immune systems, predisposing the immune system to fail to detect and eliminate newly mutated cells. …”
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Necrotizing Liver Granuloma/Abscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granul... by Sanem Eren Akarcan, Neslihan Karaca, Guzide Aksu, Halil Bozkaya, Mehmet Fatih Ayik, Yasemin Ozdemir Sahan, Mehmet Arda Kilinc, Zafer Dokumcu, Cenk Eraslan, Emre Divarci, Hudaver Alper, Necil Kutukculer

“…The devastating course of disease regardless of the mutation emphasizes the importance of early diagnosis and intervention of hematopoietic stem cell transplantation as soon as possible in children with CGD.…”
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Two Rare Complications in One Patient: Acquired von Willebrand Syndrome Associated with Intracranial Plasmacytoma by H. Auge, C. Yguel, E. Schmitt, B. Frotscher, H. Busby-Venner, R. Morizot, C. Moulin, P. Feugier, A. Perrot, L. Filliatre-Clement

“…The patient received induction therapy with bortezomib, thalidomide, and dexamethasone (VTD), followed by high-dose melphalan chemotherapy and autologous stem cell transplantation, and then VTD consolidation, and finally maintenance with lenalidomide. …”
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Demographic Profile and Clinical Characteristics of Fuchs Endothelial Corneal Dystrophy in Thai Patients: A Retrospective Cohort in a Tertiary Referral Center by Wannapanich T, Puangsricharern V, Satitpitakul V, Kittipibul T, Suphapeetiporn K

“…Trakanta Wannapanich,1,2 Vilavun Puangsricharern,1,3 Vannarut Satitpitakul,1,3 Thanachaporn Kittipibul,1,3 Kanya Suphapeetiporn4– 6 1Center of Excellence for Cornea and Stem Cell Transplantation, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 2Excellence Center for Cornea and Stem Cell Transplantation, Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; 3Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 4Department of Pediatrics, Faculty of Medicine, Chulalongkorn University Bangkok, Bangkok, Thailand; 5Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand; 6Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCorrespondence: Vilavun Puangsricharern, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand, Email vilavun@hotmail.com Kanya Suphapeetiporn, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand, Email kanya.su@chula.ac.thPurpose: To describe the demographic profile, clinical characteristics, and treatment trends of Fuchs endothelial corneal dystrophy (FECD) in Thai patients, reflecting the evolving landscape of corneal transplantation in this region.Patients and Methods: This retrospective cohort study included 900 patients (1,743 eyes) diagnosed with FECD at a tertiary referral center in Thailand between January 2017 and June 2023. …”
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Ocular Signs and Ocular Comorbidities in Monoclonal Gammopathy: Analysis of 80 Subjects by Kitti Kormányos, Klaudia Kovács, Orsolya Németh, Gábor Tóth, Gábor László Sándor, Anita Csorba, Cecília Nóra Czakó, Achim Langenbucher, Zoltán Zsolt Nagy, Gergely Varga, László Gopcsa, Gábor Mikala, Nóra Szentmáry

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RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study by Yanju Li, Xu Yang, Feiqing Wang, Feiqing Wang, Jianing Zhao, Chike Zhang, Dan Wu, Bo Yang, Rui Gao, Peng Zhao, Yun Zan, Min Su, Zhixu He, Yang Liu, Yang Liu, Yang Liu, Jishi Wang, Dongxin Tang

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Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation by Edith Pituskin, Stephen Foulkes, Rachel J. Skow, Thomas McMurtry, Calvin Kruger, Janet E. Bates, Daena Lamoureux, Joseph Brandwein, Elena Lieuw, Cynthia Wu, Nancy Zhu, Peng Wang, Daniel Sawler, Minakshi Taparia, Marlene Hamilton, Tiffany Comfort-Riddle, Tara Meyer, Gabor T. Gyenes, Ian Paterson, Carla M. Prado, Mark J. Haykowsky, Justin G. Greiner, Margaret L. McNeely, Puneeta Tandon, Richard B. Thompson

“…Abstract Background Hematopoietic stem cell transplantation (HSCT) is a common therapy for many hematologic malignancies. …”
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Integrated analysis of ATAC-seq and RNA-seq reveals ADSCP2 regulates oxidative phosphorylation pathway in hypertrophic scar fibroblasts by Qian Li, Zhe Quan, Ling Chen, Yiliang Yin, Xin Chen, Jingyun Li

“…A potential peptide, ADSCP2 (adipose-derived stem cell peptide 2, the peptide fragment of ALCAM protein), derived from adipose-derived stem cell-conditioned medium, has been identified as having the potential to mitigate hypertrophic scar formation by targeting pyruvate carboxylase. …”
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胚胎干细胞体外诱导分化为 CD34+造血前体细胞 by 周其锋, 冯炼强, 李树浓

“…【目的】胚胎干细胞( embryonic stem cell, ES)体外诱导分化,制备CD34+造血前体细胞。【方法】胚胎干细胞在含甲基纤维素培 养液中分化形成胚胎体( embryoid body, EB) ,然后加入造血刺激因子诱导产生 CD34+造血前体细胞,间接免疫荧光及流式细胞仪检测分化结 果。…”
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Messenger RNA in differentiating muscle cells—my experience in François Gros’ lab in the 1970s and 80s by Buckingham, Margaret

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Correction: Chang et al. Fabrication of Stromal Cell-Derived Factor-1 Contained in Gelatin/Hyaluronate Copolymer Mixed with Hydroxyapatite for Use in Traumatic Bone Defects. <i>Mic... by Yun-Liang Chang, Chia-Ying Hsieh, Chao-Yuan Yeh, Chih-Hao Chang, Feng-Huei Lin

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Current developments in personalized treatment strategies for elderly acute myelogenous leukemia patients by Xueting Hou, Jizhang Bao

“…Acute myelogenous leukemia(AML) is a life-threatening hematologic malignancy that predominantly affects the elderly.Currently, chemotherapy and hematopoietic stem cell transplantation are the primary treatment modalities for AML, though their clinical application is limited in older patients.Recent years have seen the development of novel molecular targeted therapies, such as isocitrate dehydrogenase 1/2 (IDH1/2) and Feline macrophage stimulator-like tyrosine kinase 3 (FLT3) inhibitors, as well as individualized approaches like chimeric antigen receptor T-cell (CAR-T) therapy.However, due to patient heterogeneity and drug resistance, treatment outcomes for elderly AML remain unsatisfactory, underscoring the need for more precise and safer individualized treatment strategies.The combination of chemotherapy with novel targeted or immunotherapies shows promise as a future treatment direction.This research reviews the latest advances in the treatment of elderly AML, with a focus on achieving more individualized and safer therapeutic approaches.…”
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Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity? by Andrea Zajacova, MD, Hélène Schoemans, MD, PhD, Mark Greer, MD, MRCP, Hildegard Greinix, MD, Peter Jaksch, MD, Osnat Shtraichman, MD, Rayid Abdulqawi, MD, PhD, Are M. Holm, MD, PhD, Robin Vos, MD, PhD, Saskia Bos, MD, PhD

“…Chronic graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation, with pulmonary chronic graft-versus-host disease (PcGvHD) particularly associated with a dismal prognosis. …”
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Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults by Eric J Bow, Gerald Evans, Jeff Fuller, Michel Laverdière, Coleman Rotstein, Robert Rennie, Stephen D Shafran, Don Sheppard, Sylvie Carle, Peter Phillips, Donald C Vinh

“…Over the past few years, a new and broader understanding of the epidemiology and pathogenesis of C/IC has emerged and has been coupled with the availability of new antifungal agents and defined strategies for targeting groups at risk including, but not limited to, acute leukemia patients, hematopoietic stem cell transplants and solid organ transplants, and critical care unit patients. …”
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The Role of Bacteria and Pattern Recognition Receptors in GvHD by E. Holler, K. Landfried, J. Meier, M. Hausmann, G. Rogler

“…Graft-versus-Host Disease (GvHD) is the most serious complication of allogeneic stem cell transplantation (SCT) and results from an activation of donor lymphocytes by recipient antigen-presenting cells (APCs). …”
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