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2681
Peptide hormones in plants
Published 2025-01-01“…The roles of peptide hormones are implicated in, but not limited to, processes such as self-incompatibility, pollination, fertilization, embryogenesis, endosperm development, stem cell regulation, plant architecture, tissue differentiation, organogenesis, dehiscence, senescence, plant-pathogen and plant-insect interactions, and stress responses. …”
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2682
Gamma delta T cells in acute myeloid leukemia: biology and emerging therapeutic strategies
Published 2024-02-01“…Insights from murine models and clinical data in humans show improved overall survival, leukemia-free survival, reduced risk of relapse, enhanced graft-versus-leukemia effect, and decreased graft-versus-host disease in patients with AML who have higher reconstitution of γδ T cells following allogeneic hematopoietic stem cell transplantation. Clinical trials leveraging γδ T cell biology have used unmodified and modified allogeneic cells as well as bispecific engagers and monoclonal antibodies. …”
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2683
Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome
Published 2014-01-01“…Six patients received hematopoietic stem cell transplantations and four of them had immune reconstructions and clinical remissions. …”
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2684
Application of Three-Dimensional Imaging to the Intestinal Crypt Organoids and Biopsied Intestinal Tissues
Published 2013-01-01“…The 3D structure of the crypt organoids from the intestinal stem cell culture and intestinal tissues from the donors and recipients after intestinal transplantation was observed using a 3D imaging system and compared with 2D histopathology and immunohistochemistry. …”
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2685
SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2
Published 2025-01-01“…Abstract Human pluripotent stem cell-derived β-cells (SC-β-cells) represent an alternative cell source for transplantation in diabetic patients. …”
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2686
Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging
Published 2025-01-01“…This review examines the molecular and cellular features common to both OSAHS and VA, highlighting decreased melatonin secretion, impaired autophagy, increased apoptosis, increased inflammation and pyroptosis, increased oxidative stress, accelerated telomere shortening, accelerated stem cell depletion, metabolic disorders, imbalanced protein homeostasis, epigenetic alterations, and dysregulated neurohormonal signaling. …”
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2687
Dysbiosis and extraintestinal cancers
Published 2025-02-01“…The oncogenic cascade always engages in the disruption of hormonal regulation and inflammatory responses, the induction of genomic instability and mutations, and the dysregulation of adult stem cell proliferation. This review aims to comprehensively summarize the existing evidence that points to the potential role of dysbiosis in the malignant transformation of extraintestinal organs such as the liver, breast, lung, and pancreas. …”
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2688
Adaptive evolution of SARS-CoV-2 during a persistent infection for 521 days in an immunocompromised patient
Published 2025-01-01“…Here we present a case study of a patient undergoing allogeneic hematopoietic stem cell transplantation with a 521-day follow-up of a SARS-CoV-2 infection with the BF.7.21 variant. …”
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2689
The Proviral Reservoirs of Human Immunodeficiency Virus (HIV) Infection
Published 2024-12-01“…Uncovering the causes of this phenomenon will bring humanity closer to curing HIV infection, potential approaches to which include stem cell transplantation, clustered regularly interspaced short palindromic repeats (CRISPR)/cas9, “Shock and kill”, “Block and lock”, and the application of broad-spectrum neutralizing antibodies (bNAbs).…”
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2690
Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders
Published 2024-12-01“…Immunomodulators, gene and RNA-based therapeutics, and stem cell methods have all shown promise for more specific and effective interventions. …”
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2691
Utility of Endoscopic Examination in the Diagnosis of Acute Graft-versus-Host Disease in the Lower Gastrointestinal Tract
Published 2017-01-01“…Of 1231 patients who underwent allogeneic hematopoietic stem cell transplantation between January 2005 and December 2014, 186 of whom underwent colonoscopy and biopsy and had no cytomegalovirus infection. …”
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2692
VEGF Promotes Proliferation of Human Glioblastoma Multiforme Stem-Like Cells through VEGF Receptor 2
Published 2013-01-01“…In this study, human GBSCs were isolated from surgical specimens of glioblastoma and cultured in medium favored for stem cell growth. Neural Colony-Forming Cell Assay and ATP assay were performed to measure GBSC proliferation under normoxia (20% O2) and hypoxia (1% O2). …”
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2693
Erythropoietin, Forkhead Proteins, and Oxidative Injury: Biomarkers and Biology
Published 2009-01-01“…Here we present the exciting as well as the complex role that EPO and FoxOs possess to uncover the benefits as well as the risks of these agents for cell biology and clinical care in processes that range from stem cell development to uncontrolled cellular proliferation.…”
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2694
An Analysis of the Progression of Conjunctivalisation after Transplantation of Cultivated Corneal Epithelium
Published 2021-01-01“…Forty-eight eyes underwent autologous transplantation of cultivated corneal epithelium to treat partial or total limbal stem cell deficiency caused by chemical or thermal injury. …”
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2695
Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside
Published 2011-01-01“…Chronic Graft Versus Host Disease (cGVHD) is a major complication of allogeneic stem-cell transplantation (SCT). In many inflammatory fibrotic diseases, such as Systemic Scleroderma (SSc) and cGVHD with fibrotic features, an abnormal activation of transforming growth factor (TGFβ) and platelet-derived growth factor receptor (PDGF-R) pathways have been observed. …”
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2696
Machine Learning and Medical Data: Predicting ICU Mortality and Re-admission Risks
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2697
Plants and fungi metabolites as novel autophagy inducers and senescence inhibitors
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2698
Concurrent Central Diabetes Insipidus and Acute Myeloid Leukemia
Published 2021-01-01“…The patient received induction chemotherapy followed by allogeneic hematopoietic stem cell transplantation but experienced disease relapse and passed away nine months after initial diagnosis. …”
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2699
Acute Coronary Syndrome as an Unusual Initial Presentation of T-Prolymphocytic Leukemia: A Case Report and Review of the Literature
Published 2024-01-01“…The patient was then eligible to undergo a consolidating allogeneic stem cell transplant (alloSCT). The reported case shows that T-PLL can also become initially symptomatic through an acute coronary syndrome on the basis of complex coronary heart disease. …”
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2700
Mucormycosis Leading to Cerebral Edema and Cerebellar Tonsillar Herniation after Allogeneic Bone Marrow Transplant: A Case Report
Published 2019-01-01“…Mucormycosis following hematopoietic stem cell transplant (HSCT) carries a very high mortality rate. …”
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